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Search Results: 1 - 10 of 533809 matches for " M Elena; Labra G "
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Leucemia linfoma T del adulto en Chile.: Estudio clínico-patológico y molecular de 26 pacientes Adult T cell leukemia lymphoma in Chile.: A clinico pathological and molecular study of 26 patients
M Elena Cabrera C,Silvia Labra G,Pedro Meneses C,Estella Matutes
Revista médica de Chile , 1999,
Abstract: Background: Adult T cell leukemia lymphoma is a lymphoproliferative syndrome etiologically associated to human T cell lymphotropic virus type I. Aim: To describe the clinical and laboratory features of 26 Caucasian Chilean patients, with HTLV-I positive adult T-cell leukemia lymphoma (ATLL). Material and methods: Diagnostic criteria included clinical features, cell morphology, immunophenotype, HTLV-I serology and/or DNA analysis by Southern blot or PCR. Results: According to the clinical presentation, 12 cases had the acute ATLL form, 6 had a lymphoma, 4 the chronic form and 4 had smoldering ATLL. The median presentation age was 50 years, younger than the Japanese patients, but significantly older than patients from other South American countries (eg Brasil, Jamaica, Colombia). The main clinical features: lymphadenopathy, skin lesions and hepatosplenomegaly, were similar in frequency to those of patients from other countries, except for the high incidence of associated neurological disease. Tropical Spastic Paraparesis (TSP) in our series of ATLL, was seen in one third of the patients (8/26). A T-cell immunophenotype was shown in all 26 cases and HTLV-I serology was positive in 25/26 patients. Molecular analysis on the seronegative patient showed clonal integration of proviral HTLV-I DNA into the lymphocytes DNA, and thus he may have been a poor responder to the retroviral infection. Proviral DNA integration was also demonstrated in 15/16 patients being clonal in 10, polyclonal in 3 (all smoldering cases) and oligoclonal in one. Conclusions: ATLL in Chile has similar clinical and laboratory features than the disease in other parts of the world, except for a younger age than Japanese patients but older than those from other Latin American countries and a high incidence of patients with associated TSP. Detailed morphological and immunophenotypic analysis of the abnormal circulating lymphocytes, together with the documentation of HTLV-I by serology and/or DNA analysis are key tests for the identification of this disease.
Leucemia linfoma T del adulto en Chile.: Estudio clínico-patológico y molecular de 26 pacientes
Cabrera C,M Elena; Labra G,Silvia; Meneses C,Pedro; Matutes,Estella; Cartier R,Luis; M Ford,Anthony; F Greaves,Melvyn;
Revista médica de Chile , 1999, DOI: 10.4067/S0034-98871999000800007
Abstract: background: adult t cell leukemia lymphoma is a lymphoproliferative syndrome etiologically associated to human t cell lymphotropic virus type i. aim: to describe the clinical and laboratory features of 26 caucasian chilean patients, with htlv-i positive adult t-cell leukemia lymphoma (atll). material and methods: diagnostic criteria included clinical features, cell morphology, immunophenotype, htlv-i serology and/or dna analysis by southern blot or pcr. results: according to the clinical presentation, 12 cases had the acute atll form, 6 had a lymphoma, 4 the chronic form and 4 had smoldering atll. the median presentation age was 50 years, younger than the japanese patients, but significantly older than patients from other south american countries (eg brasil, jamaica, colombia). the main clinical features: lymphadenopathy, skin lesions and hepatosplenomegaly, were similar in frequency to those of patients from other countries, except for the high incidence of associated neurological disease. tropical spastic paraparesis (tsp) in our series of atll, was seen in one third of the patients (8/26). a t-cell immunophenotype was shown in all 26 cases and htlv-i serology was positive in 25/26 patients. molecular analysis on the seronegative patient showed clonal integration of proviral htlv-i dna into the lymphocytes dna, and thus he may have been a poor responder to the retroviral infection. proviral dna integration was also demonstrated in 15/16 patients being clonal in 10, polyclonal in 3 (all smoldering cases) and oligoclonal in one. conclusions: atll in chile has similar clinical and laboratory features than the disease in other parts of the world, except for a younger age than japanese patients but older than those from other latin american countries and a high incidence of patients with associated tsp. detailed morphological and immunophenotypic analysis of the abnormal circulating lymphocytes, together with the documentation of htlv-i by serology and/or dna analysis
Encefalitis herpética neonatal: dos gemelas, dos casos
Conca M,Natalia; Labra?a C,Yenis; Bercovich W,Mariana; Cienfuegos S,Guillermo; Santolaya De P,M. Elena;
Revista chilena de infectología , 2011, DOI: 10.4067/S0716-10182011000300010
Abstract: herpes simplex encephalitis is an infrequent infection with high mortality and morbidity. antiviral therapies decrease mortality but long term sequelae are still high, so early diagnosis is important for opportune treatment. we present a pair of twins with central nervous system herpes simplex infection during the first month of life. both twins presented non-specific symptoms and consulted with 48 hours apart needing intensive care admission, the first one for noninvasive mechanical ventilation and the second for hemodynamic support. diagnosis was made by cerebrospinal fluid pcr, in the first twin at day 9 of disease and in the second at admission. both twins were treated with acyclovir, but only the second one at the beginning of her illness. initial study with electroencephalogram and magnetic resonance was normal and cerebrospinal fluid on day 18 of treatment was negative for herpes simplex virus dna detection in both patients.
Efectos proinflamatorios de la contaminación atmosférica Proinflammatory effects of air pollution in Santiago de Chile
Manuel Oyarzún G,Nelson Dussaubat D,M. Eugenia Miller A,Silvia Labra J
Revista Chilena de Enfermedades Respiratorias , 2011,
Abstract: La exposición intermitente de ratas centinela a la contaminación del tráfico vehicular de Santiago se ha asociado a disminución del crecimiento corporal después de cien días de exposición (rango: 101-111) y a da o histopatológico del pulmón a los 90 días y más, especialmente a los 180 días de exposición. Nuestro objetivo fue evaluar si la exposición al aire de una avenida con elevado tráfico vehicular durante 90 días era capaz de inducir en la rata una respuesta inflamatoria sistémica. Ratas Sprague-Dawley de 30 días de edad (n = 7) fueron directamente expuestas a respirar el aire de una avenida con elevado flujo vehicular (8 h, 5 días por semana, desde el 27 de abril hasta el 29 de julio de 2009). Las ratas control (n = 7) respiraron aire del bioterio. Las ratas se pesaron dos veces por semana y después de completar 90 días de observación, los pulmones se destinaron a estudio histopatológico. Se realizó microhematocrito y se determinó proteína C reactiva, viscosidad y F2-isoprostano plasmáticos en muestras de sangre. La exposición a PM10, PM2,5, ozono, NO2 y CO se calculó de los registros de cuatro estaciones de monitoreo de Santiago. Después de 90 días de exposición se observó un aumento significativo (p < 0,05) de la proteína C reactiva y de la viscosidad plasmática y también del microhematocrito, en relación a la serie control. No se observaron cambios significativos en F2-isoprostano plasmático, ni en la histopatología pulmonar, ni en la curva de peso corporal versus tiempo al comparar la serie expuesta con la serie control. El promedio horario de PM2,5 en las 8 horas de exposición fue alto: 38,9 μg/m3. Concluimos que 90 días de exposición intermitente a la contaminación aérea de Santiago en el modelo experimental promueve una reacción inflamatoria sistémica. Esta respuesta a la contaminación aérea podría preceder a la disminución del crecimiento corporal y al da o histológico pulmonar encontrado en otro de nuestros estudios en esta misma especie después de la exposición intermitente a la contaminación aérea de Santiago. Intermittent exposure of rats to Santiago's traffic pollution is associated to a decrease in growth after more than 100 days (range: 101-111) and to histological lung damage after 90 and particularly after 180 days. Our aim was to assess whether a 90 days exposure of rats to air from a Santiago's heavy traffic avenue, is able to induce a systemic proinflammatory reaction. Thirty-days-old Sprague-Dawley rats (n = 7) were directly exposed to air from a heavy traffic avenue (8 h, 5 days a week, from April 27 to July 29, 2009). Controls
El comercio de servicios de educación en el contexto de la OMC. Elementos para un debate desde México
Armando Labra M.
Perfiles educativos , 2003,
Abstract:
Efectos proinflamatorios de la contaminación atmosférica
Oyarzún G,Manuel; Dussaubat D,Nelson; Miller A,M. Eugenia; Labra J,Silvia; González B,Sergio;
Revista chilena de enfermedades respiratorias , 2011, DOI: 10.4067/S0717-73482011000300002
Abstract: intermittent exposure of rats to santiago's traffic pollution is associated to a decrease in growth after more than 100 days (range: 101-111) and to histological lung damage after 90 and particularly after 180 days. our aim was to assess whether a 90 days exposure of rats to air from a santiago's heavy traffic avenue, is able to induce a systemic proinflammatory reaction. thirty-days-old sprague-dawley rats (n = 7) were directly exposed to air from a heavy traffic avenue (8 h, 5 days a week, from april 27 to july 29, 2009). controls (n = 7) breathed animal room air. rats were weighed twice a week and after completing 90 days of observation, lungs were subjected to histopathology and c reactive protein, viscosity and f2-isoprostane in plasma and microhematocrit were determined in blood samples. exposure to pm10, pm2.5, ozone, no2 and co were estimated from registrations of 4 santiago's monitoring stations. plasmatic c reactive protein and viscosity and microhematocrit were significantly increased after 90 days of exposure as compared to controls (p < 0.05). no significant changes were observed in f2-isoprostane, nor in lung histopathology, nor in body weight curve versus time in exposed as compared to control series. hourly mean value of pm25 in the 8 h of exposure was high: 38.9 μg/m3. it is concluded that 90 days of intermittent exposure of rats to santiago's air pollution would promote a systemic inflammatory reaction. this response to air pollution might precede the decrease in body growth and the histological lung damage reported previously by our laboratory in the same species after intermittent santiago's urban air pollution exposure.
Institutional change and political decision-making in the creation of the Brazilian National Health Surveillance Agency
Piovesan, Márcia Franke;Labra, Maria Eliana;
Cadernos de Saúde Pública , 2007, DOI: 10.1590/S0102-311X2007000600012
Abstract: this article examines the decision-making process that led to the creation of the brazilian national health surveillance agency (anvisa) in 1999. the authors begin by discussing the history of the agency's predecessor, the health surveillance secretariat, and the need for its modernization to adjust the quality of the products under its control to domestic and international demands. from the theoretical perspective of neo-institutionalism, the article goes on to analyze the social and political context surrounding the debate on the proposed alternatives to adjust health surveillance to new rules in line with such requirements, focusing especially on the formulation of the new policy, the decision-making arena, and the actors with specific interests in the sector. the research drew on extensive documentary and media material, plus interviews with key actors. the article concludes that a determinant factor for the creation of anvisa was the favorable domestic political context, fostering a positive correlation of forces that (in an extremely short timeframe, 1998-1999) allowed the creation of the first regulatory agency in the social policies area in brazil.
First Characterization of Escherichia coli Strains Isolated from Wildlife Griffon Vulture (Gyps fulvus) in the Southeast of Spain  [PDF]
Azucena Mora, Nieves Ortega, Elena Garcia, Susana Viso, Mónica G. Candela, Ghizlane Dahbi, Francisco Cuello, María Rosa Caro
Open Journal of Veterinary Medicine (OJVM) , 2014, DOI: 10.4236/ojvm.2014.412040
Abstract: The aim of the present study was to characterize a collection of Escherichia coli strains isolated from asymptomatic griffon vulture (Gyps fulvus) during a reintroduction program in the southeast of Spain, in order to establish if griffon vulture could play a role in the spread of resistant or potentially pathogenic E. coli strains. For this purpose, 14 E. coli strains obtained from 10 griffon vulture were studied to establish their serotypes, phylogroups, virulencegene profiles and antimicrobial resistances. High heterogeneity was observed within the 14 strains isolated which belonged to three phylogroups (A, B1 and D), 8 serogroups (O2, O21, O29, O60, 073, O78, O103 and O141) and 13 different serotypes. Out of 34 genes screened, we have detected eight virulence genes that are typical of extraintestinal pathogenic E. coli (ExPEC) (fimH, fimAvMT78, iroN, iucD, cvaC, iss, traT and tsh); however, none of the studied strains showed the ExPEC status. The 14 strains were also analyzed for the production of extended-spectrum beta-lactamases (ESBLs) and for antimicrobial resistances. None of the 14 strains were ESBL-producing E. coli, but high resistance-prevalences to ampicillin and cotrimoxazole were detected. To our knowledge, this is the first characterization of E. coli strains isolated from griffon vulture and although they did not show high virulencegene scores, they showed cotrimoxazole resistance.
Linguistic issues in reports about the Lisbon Earthquake of 1755, typical of pre-journalistic speech Aspectos lingüísticos propios del discurso pre-periodístico en las relaciones sobre el Terremoto de Lisboa de 1755
Elena LEAL ABAD,Elena MéNDEZ G.a DE PAREDES
Cuadernos Dieciochistas , 2013,
Abstract: The reports that constitute the corpus of study for this work describe the devastating effects of the Lisbon earthquake of 1755. The fact that natural disasters are a thematic invariant of informative discourse will allow us better to trace the evolution of the syntax used in this type of discourse. It should be noted, however, that not all reports have the same syntactic formation: some belong fully to what we could call the discourse of modernity, more closely connected, therefore, with the language of journalistic discourse today. Others, notwithstanding the date, have a more archaic and extremely complex syntax, which cannot be taken as the origin of modern expository discourse. This analysis will provide a clear evidential basis that will serve as a starting point to then analyse the evolution of journalistic language in relation to the textual changes that would gradually consolidate new information genres. Las relaciones que constituyen el corpus de estudio para este trabajo relatan los efectos devastadores del terremoto de Lisboa de 1755. El hecho de que las catástrofes naturales sean una invariante temática del discurso informativo permitirá rastrear mejor la evolución de la sintaxis de este tipo de discurso. No obstante, hay que tener en cuenta que no todas tienen la misma conformación sintáctica: unas pertenecen de lleno a lo que podríamos llamar el discurso de la modernidad, más entroncadas, por tanto, con la lengua del discurso periodístico actual. Otras, pese a la fecha, tienen una sintaxis más arcaizante y extremadamente compleja, incapaz de ser tenidas como origen del discurso informativo. De este análisis se obtendrá una base empírica clara que servirá de punto de partida para analizar luego la evolución de la lengua periodística en relación con los cambios textuales que irán consolidando nuevos géneros informativos.
A magnetovariational study in Central Italy: Standard techniques
E. Bozzo,G. Caneva,A. Elena,M. Gambetta
Annals of Geophysics , 1994, DOI: 10.4401/ag-4175
Abstract: magnetovariational study was performed in Central Italy, with an array of magnetometers located at Radicondoli (SI), Radda in Chianti (SI), Roccalbegna (GR), Città di Castello (PG) and Pennabilli (PS) from February to May 1992. Geomagnetic transfer functions in the frequency domain were calculated using the standard least squares tecnique. The induction arrows for the periods T= 32 min and T= 128 min, the Hypothetical Event (HE) maps and two IZ/HI pseudosections across the array, show the magnetovariational effect of the upper mantle anomaly in the Tuscan-Tyrrhenian area and the contrast between different crustal types.
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