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Search Results: 1 - 10 of 402229 matches for " M Ansari-Lari "
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Hematological Changes in Nurses Handling Antineoplastic Drugs
M Ansari-Lari,M Saadat
Iranian Journal of Public Health , 2002,
Abstract: A cross-sectional study to determine whether occupational exposure to antineoplastic drugs can cause hematologic changes was performed. Blood samples were collected from a group of 24 hematology/oncology nurses who were exposed to antineoplastic drugs during a mean preiod of 5.5 years (standard error =1.1). The control group, matched by sex, and age, consisted of 18 nurses, worked on other sections. Within the normal range we found significant differences between the exposed and the control group in the absolute mean number of the total white blood cells (t=-2.50; df=40; P<0.05) and neutrophils (t=-1.72; df=40; P<0.05; one tailed test). The findings suggested, that the hematologic changes can serve as biological markers for medical surveillance and early detection of health problems due to handling antineoplastic drugs.
"Sister Chromatid Exchanges and Micronuclei in Lymphocyte of Nurses Handling Antineoplastic Drugs"
M Ansari-Lari,M Saadat,M Shahryari,DD Farhud
Iranian Journal of Public Health , 2001,
Abstract: Individuals handling antineoplastic drugs or their wastes may absorb these potent genotoxic agents. The effects of handling antineoplastic drugs were examined in a group of 24 nurses working in the hematology and oncology departments of two different university hospitals in Shiraz (Iran) and in a group of 18 unexposed nurses as control group. The cytogenetic repercussions of exposure were assessed by examining sister chromatid exchanges (SCEs) and micronuclei (Mn) in circulating lymphocytes. A significant increased frequencies of SCE and Mn is observed in circulating lymphocytes. A significant increased frequencies of SCE and Mn is observed in nurses in daily contact with antineoplastic drugs as compared to control group.
Genetic Polymorphism of Glutathione S-transferase T1, M1 and Asthma, A Meta-analysis of the Literature
Mostafa Saadat,Maryam Ansari-Lari
Pakistan Journal of Biological Sciences , 2007,
Abstract: Published studies have confirming or refusing an association between either glutathione S-transferase T1 (GSTT1) or M1 (GSTM1) polymorphism and asthma risk. Therefore the present meta-analysis was done. Literature-based meta-analysis was supplemented by tabular data from investigators of all relevant studies of two GST polymorphism (GSTM1 and GSTT1) available before May 2006, with investigation of potential sources of heterogeneity. Included in the resent study were 14 studies, involving a total 2292 asthma patients and 5718 controls. We found substantial evidence of heterogeneity between the studies. Exclusion of two studies with lowest quality scores resulted in a dramatic decrease in heterogeneity. The overall OR of the asthma risk associated with GSTM1 null genotype was 1.20 (95% CI: 1.08-1.35). Stratifying the meta-analysis by age and smoking status of subjects, the pooled ORs for GSTM1 null genotype were 1.56 (95% CI: 1.25-1.94) in adults and 1.95 (95% CI: 1.21-3.13) in non-smokers. The GSTT1 null genotype was associated with asthma risk in non-smoker adults (OR = 2.06, 95% CI: 1.21-3.71). To investigate whether profile of GST genotypes are associated with the risk of the asthma, further analysis combining the GSTT1 and GSTM1 genotypes were also carried out. Subjects with null genotypes for both GSTM1 and GSTT1 were at a significant higher risk for developing
Causes of culling in dairy cows and its relation to age at culling and interval from calving in Shiraz, Southern Iran
Maryam Ansari-Lari,Mehdi Mohebbi-Fani,Abbas Rowshan-Ghasrodashti
Veterinary Research Forum , 2012,
Abstract: This study was designed to investigate causes of culling in industrial dairy herds in Fars province and to describe the pattern of reason-specific culling with respect to age of animal and interval from calving to culling. A total number of 9 dairy herds were selected for the study and information about culling reasons, birth date, last calving date and culling date was collected for culled cows during 2005- 2006. Infertility (32.6% of all culls) was the most prevalent reason of culling followed by mastitis (6.5%). The time interval from last calving to culling averaged 240 days (SD = 176) and nearly 28% of cows were culled in the first 100 days after calving. Mean age of animals at culling was 6 years (SD = 2.7) and median was 5.7 years. In Cox proportional hazard model for calving to culling interval, infertility (hazard ratio [HR] = 0.26) showed lower risk whereas mastitis (HR = 2.40), left displaced abomasum (HR = 2.60) and peripartum problems (HR = 2.60) had higher risk of culling compared with voluntary cull. In the Cox model for age at culling, risk of culling was significantly higher for infertility (HR = 1.70), left displaced abomasum (HR = 3.15), and peripartum problems (HR = 2.10) compared with voluntary culling. In conclusion, farmers tend to keep infertile cows for longer period from calving to culling while infertile cows are generally culled at younger age. Also, early culling appeared to have a high proportion of culls in the studied herds.
Analysis Neotectonic Activities in Khafr Basin  [PDF]
Ahmad Ansari Lari, Maryam Ansari, Soraya Ansari
Open Journal of Geology (OJG) , 2016, DOI: 10.4236/ojg.2016.66040
Abstract: As Iran is located on one of the two earthquake-prone belts in the world, and existence of faults and earthquakes is normal in Iran tableland. The main reason of earthquake is Neotectonic movements which can be effective in other natural disasters such as range movements. Due to the severe shortage of historical and seismic data and device in different parts of the world, particularly Iran, need for introducing more researchers and planners of Iran to tectonics and active tectonic areas is more visible. This study is an investigation of Neotectonic activities in Khafr basin area, Fars province. To achieve the aims of this study morphometric parameters were used. Investigations showed that severity and role of tectonic activities in different parts of the basin isdifferent, results of geomorphic and tectonic assessments indicate these differences.Stream length-gradient index (SL)on the main stream is inactive and sub streams are semi active, the ratio of the basin (BS)is 2.27, drainage basin asymmetry index (AF)is in semi active class, the ratio of width to depth of Valley (VF
Diuretic Effects of Several Chemical and Herbal Compounds in Adult Laying Hens
A. Esfandiary,H. Rajaian,K. Asasi,M. Ansari Lari
International Journal of Poultry Science , 2010,
Abstract: Diuretic agents have been used in the treatment of several situations such as cardiopulmonary and urinary diseases in humans and animals, but they have not been extensively studied in poultry. Some Iranian poultry producers traditionally use urotropin (hexamine), alhagi (Camelorum fisch) and malt beverage to get therapeutic effect in broiler or laying hens. Diuretics may be used after drug therapy in order to get rid of tissue residues and in some toxicity conditions in birds. The purpose of this study was to evaluate the diuretic properties of several herbal and chemical agents in adult laying hens. Adult laying hens were randomly divided into 9 groups, each group consisting of 5 birds. Specific doses of diuretics were administrated to anesthetized hens (with xylazine and ketamine) following 24 h off-feed period. Urine samples were collected for 2 h after drug administration. Blood samples were also taken at 90 min. The concentrations of chloride, albumin, glucose, creatinine, uric acid and urea nitrogen were measured in serum and urine samples. Urine volume and specific gravity, sodium and potassium concentrations were also determined in urine. Statistical analysis of data showed that furosemide had a positive significant effect on urine volume compared to other agents. Urotropin also increased the urine volume but this effect was not significant. With respect to the effects on electrolytes (sodium, potassium and chloride), intramuscular furosemide, oral urotropin and hydrochlorothiazide exerted some changes, but no consistent pattern was observed with respect to the other factors measured in serum and/or in urine. Diuretic effect was more pronounced following intramuscular administration of furosemide.
Evaluation of Sialic Acid and Acute Phase Proteins (Haptoglobin and Serum Amyloid A) in Clinical and Subclinical Bovine Mastitis
S. Nazifi*, M. Haghkhah1, Z. Asadi, M. Ansari-Lari2, M. R. Tabandeh3, Z. Esmailnezhad and M. Aghamiri
Pakistan Veterinary Journal , 2011,
Abstract: The present study was conducted to evaluate the concentrations of sialic acids (total, lipid bound and protein bound) and their correlation with acute phase proteins (haptoglobin and serum amyloid A) in clinical and subclinical mastitis of cattle. Thirty subclinical mastitic cows with positive California mastitis test (CMT) test and no clinical signs of mastitis, 10 clinical mastitic cows and 10 healthy cows with negative CMT test and normal somatic cell count were selected. Milk and blood samples were collected after confirmation of clinical and subclinical mastitis by somatic cell count and bacterial identification. Serum haptoglobin (Hp), serum amyloid A (SAA), total sialic acid (TSA), lipid bound sialic acid (LBSA) and protein bound sialic acid (PBSA) were measured by validated standard methods. Haptoglobin and SAA increased significantly in both types of mastitis compared with control group (P<0.001). However, the ratio of HP/SAA was significantly different from the control group only in clinical mastitis. The results showed that TSA and LBSA were significantly different in control group compared with clinical and subclinical mastitis (P<0.001). Protein bound sialic acid did not change in subclinical mastitis in comparison with control group (P=0.86). There was positive correlation between LBSA and PBSA in clinical mastitis (r=0.72, P=0.02) whereas significant negative correlation was observed between LBSA and PBSA in subclinical mastitis (r=-0.62, P<0.001). Results also showed no correlation between Hp and SAA with each other or with any other parameters in study groups.
Status of General Practice and Challenges to Healthcare System of Pakistan  [PDF]
Rashid M. Ansari, Yusra Ansari, Saiqaa Y. Ansari
Open Journal of Preventive Medicine (OJPM) , 2015, DOI: 10.4236/ojpm.2015.512052
Abstract: This article provides insight into the status of general practice in Pakistan and challenges to its health care system. The country ranked 122nd on the overall health system attainment and ranked 7th in the world on diabetes prevalence. The public sector health care system in Pakistan is encountered with many problems such as structural fragmentation, resource scarcity, inefficiency and lack of functional specificity, gender insensitivity and inaccessibility. The general practice status in Pakistan requires immediate attention to face the challenges created by chronic diseases in the country. Of particular mention are the patient-doctor interaction, healthcare system delivery, access to the doctors and better utilization of primary health care services.
Primary Healthcare System of Pakistan: Challenges to Self-Management of Type 2 Diabetes  [PDF]
Rashid M. Ansari, Hassan Hosseinzadeh, Nicholas Zwar
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2016, DOI: 10.4236/ojemd.2016.67023
Abstract: This review article is aimed at describing the primary healthcare system of Pakistan and its challenges in the face of epidemic of type 2 diabetes, focusing particularly on the middle-aged population of rural area of Pakistan. The main concern in Pakistan is that its middle-aged population is facing the onslaught of obesity and overweight due to lack of physical activity. In addition unhealthy eating habits making it more difficult for this population to control their weight. All these factors are contributing to a high risk of type 2 diabetes for the population of Pakistan. This article provides insight into the primary health care system of Pakistan and highlights its deficiencies by identifying that its primary healthcare system has a poor utilization of health care services, the poor accessibility to health system and poor management of diabetes by the healthcare system, gender disparity and inequity in the health care system. The primary objective of this study is to provide an overview of self-management of diabetes among the middle-aged population of Pakistan and to identify the overall deficiencies in the primary healthcare system, its delivery and access to the system, barriers to self-management of diabetes and quality of life in that region.
A Case of S L E Complicated by a Peritonitis " Lupus Prritonitis "
M.M. Lari,P. Isfahanizadeh
Acta Medica Iranica , 1976,
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