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Search Results: 1 - 10 of 297330 matches for " Lynae J. Hanks "
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Macronutrient Intake Influences the Effect of 25-Hydroxy-Vitamin D Status on Metabolic Syndrome Outcomes in African American Girls
Anna L. Newton,Lynae J. Hanks,Ambika P. Ashraf,Elizabeth Williams,Michelle Davis,Krista Casazza
Cholesterol , 2012, DOI: 10.1155/2012/581432
Abstract: The objectives were to determine the effect of macronutrient modification on vitamin D status and if change in 25-hydroxy-vitamin D concentration influences components of metabolic syndrome in obese African American girls. Methods. Five-week intervention using reduced CHO (43% carbohydrate; 27% fat: SPEC) versus standard CHO (55% carbohydrate; 40% fat: STAN) eucaloric diet. Subjects were 28 obese African American females, aged 9–14 years. Dual energy X-ray absorptiometry and meal test were performed at baseline and five weeks. Results. Approximately 30% of girls had metabolic syndrome. Serum 25OHD increased in both groups at five weeks [STAN: 20.3 ± 1.1 to 22.4 ± 1.1 (<0.05) versus SPEC: 16.1±1.0 to 16.8±1.0 (=0.05)]. The STAN group, increased 25OHD concentration over five weeks (<0.05), which was positively related to triglycerides (<0.001) and inversely associated with total cholesterol (<0.001) and LDL (<0.001). The SPEC group, had increase in 25OHD (=0.05), which was positively related to fasting insulin (<0.001) and insulin sensitivity while inversely associated with fasting glucose (<0.05). The contribution of vitamin D status to metabolic syndrome parameters differs according to macronutrient intake. Improvement in 25OHD may improve fasting glucose, insulin sensitivity, and LDL; however, macronutrient intake warrants consideration.
Macronutrient Intake Influences the Effect of 25-Hydroxy-Vitamin D Status on Metabolic Syndrome Outcomes in African American Girls
Anna L. Newton,Lynae J. Hanks,Ambika P. Ashraf,Elizabeth Williams,Michelle Davis,Krista Casazza
Cholesterol , 2012, DOI: 10.1155/2012/581432
Abstract: The objectives were to determine the effect of macronutrient modification on vitamin D status and if change in 25-hydroxy-vitamin D concentration influences components of metabolic syndrome in obese African American girls. Methods. Five-week intervention using reduced CHO (43% carbohydrate; 27% fat: SPEC) versus standard CHO (55% carbohydrate; 40% fat: STAN) eucaloric diet. Subjects were 28 obese African American females, aged 9–14 years. Dual energy X-ray absorptiometry and meal test were performed at baseline and five weeks. Results. Approximately 30% of girls had metabolic syndrome. Serum 25OHD increased in both groups at five weeks [STAN: 20.3 ± 1.1 to 22.4 ± 1.1 ( ) versus SPEC: to ( )]. The STAN group, increased 25OHD concentration over five weeks ( ), which was positively related to triglycerides ( ) and inversely associated with total cholesterol ( ) and LDL ( ). The SPEC group, had increase in 25OHD ( ), which was positively related to fasting insulin ( ) and insulin sensitivity while inversely associated with fasting glucose ( ). The contribution of vitamin D status to metabolic syndrome parameters differs according to macronutrient intake. Improvement in 25OHD may improve fasting glucose, insulin sensitivity, and LDL; however, macronutrient intake warrants consideration. 1. Introduction The steady rise in prevalence of pediatric obesity over the past three decades has been accompanied by accumulation of risk factors for metabolic syndrome (MetSyn) in childhood and adolescence. The occurrence of hypovitaminosis D (expressed as levels <20?ng/mL of circulating 25-hydroxy vitamin D (25OHD)) has been increasingly documented in the same population [1, 2]. Moreover, children/adolescents with hypovitaminosis D have been reported to experience greater instances of hypertension, hypertriglyceridemia, hyperglycemia, and low high-density lipoprotein cholesterol (HDL) [1, 3, 4]. Further, it has been proposed that elevated parathyroid hormone (PTH), consequential to chronic low vitamin D level, is mechanistically involved in the adverse perturbations of risk factors underlying MetSyn [5]. Given the emerging identification of vitamin D as an integral player in numerous metabolic pathways, it stands to reason that vitamin D status in the pediatric populace may play a role in the prevalence of metabolic disease risk factors [6, 7]. The relationship between 25OHD status and metabolic health is not equally distributed across groups. In particular, the relationship is more apparent among African American (AA) females, particularly those who are overweight/obese
Mammoths, Mastodonts & Elephants Biology, Behaviour, and the Fossil Record/Gary Haynes
J. Hanks
African Zoology , 2011,
Abstract: In a decade of fieldwork and research, much of it taking place in Zimbabwe's Hwange National Park, Gary Haynes came to realise that most of the alleged facts about proboscideans are fabrications whose foundations are exceptionally shaky. Using a combination of an incredibly diligent literature search, and his own meticulously recorded fieldwork, Haynes has attempted to 'reconstruct' the behaviour of extinct mammoths and mastodonts based on what can be observed of modern elephants and the concept that a living species is a good parallel to an extinct one. He has succeeded admirably, and has produced a work of scholarship to be savoured not only by palaeontologists, but by all who are interested in the anatomy, behaviour and ecology of Africa's megafauna.
Understanding Jet Energy Loss with Angular Correlation Studies in PHENIX
J. A. Hanks
Physics , 2010,
Abstract: Angular correlation studies provide powerful insight into the energy loss of hard scattered partons as they traverse the partonic medium produced in heavy ion collisions at RHIC. These results are generally compared to jet correlations in p+p collsisions where all correlation strength is attributed to vacuum fragmentation. Strong modification to di-jet correlations has been observed in A+A collisions at RHIC, most notably for the away side jet. Many different effects, including the opacity of the medium, its response to energy deposited by partons as they propagate, and modifications to the parton fragmentation, are involved in producing the final correlation stuctures. Understanding the interplay between these various effects is essential to developing a complete picture of the medium. Measurements of jet correlations involving direct photons provide a unique probe of jet fragmentation effects, as photons are not strongly interacting. Additionally, systematic studies of the away side structure as a function of $p_{T}$, as well as attempts to include additional high $p_{T}$ trigger requirements, can help to distinguish different energy loss mechanisms. We discuss recent PHENIX results from these detailed studies of jet correlations in A+A and p+p collisions.
ABC transporter FtsABCD of Streptococcus pyogenes mediates uptake of ferric ferrichrome
Tracey S Hanks, Mengyao Liu, Michael J McClure, Benfang Lei
BMC Microbiology , 2005, DOI: 10.1186/1471-2180-5-62
Abstract: Recombinant FtsB, the lipoprotein component of FtsABCD, was found to bind Fe3+ ferrichrome in a 1:1 stoichiometry. To investigate whether FtsABCD transports Fe3+ ferrichrome, GAS isogenic strains defective in lipoprotein gene ftsB and permease gene ftsC were generated, and the effects of the mutations on uptake of Fe3+ ferrichrome were examined using radioactive 55Fe3+ ferrichrome. FtsB was produced in the wild-type strain but not in the ftsB mutant, confirming the ftsB inactivation. While wild-type GAS took up 3.6 × 104 Fe3+ ferrichrome molecules per bacterium per min at room temperature, the ftsB and ftsC mutants did not have a detectable rate of Fe3+ ferrichrome uptake. The inactivation of ftsB or ftsC also decreased 55Fe3+ ferrichrome uptake by >90% under growth conditions in the case of limited uptake time. Complementation of the ftsB mutant with a plasmid carrying the ftsB gene restored FtsB production and 55Fe3+ ferrichrome association at higher levels compared with the parent strain. The inactivation of mtsA and htsA and Fe-restricted conditions enhanced the production of FtsB and Fe3+ ferrichrome uptake.The FtsB protein bound Fe3+ ferrichrome, and inactivation of ftsB or ftsC, but not htsA or mtsA, diminished Fe3+ ferrichrome uptake, indicating that FtsABCD, but not HtsABC and MtsABC, is the transporter that takes up Fe3+ ferrichrome in GAS. Fe acquisition systems are virulence factors in many bacterial pathogens and are attractive vaccine candidates. The elucidation of the FtsABCD specificity advances the understanding of Fe acquisition processes in GAS and may help evaluating the GAS Fe acquisition systems as vaccine candidates.Ferric iron (Fe3+), the stable iron form in an oxidative environment, has extremely low solubility in water under physiological conditions, and mammalian hosts thus do not have sufficient free Fe3+ to support bacterial growth [1]. The major sources of iron in vivo for bacteria are host heme-proteins and other iron complexes [1,2].
Pain Assessment and Management in Aging
Hanks-Bell, M., Halvey, K., Paice, J
Online Journal of Issues in Nursing , 2004,
Abstract: Pain in the absence of disease is not a normal part of aging, yet it is experienced daily by a majority of older adults in the United States. Older adults are at high risk for undertreatment of pain due to a variety of barriers. These include lack of adequate education of health care professionals, cost concerns and other obstacles related to the health care system, and patient related barriers, such as reluctance to report pain or take analgesics. Unrelieved pain in the older adult has significant functional, cognitive, emotional, and societal consequences. Pain control begins with a thorough assessment, including an extensive history and physical examination. This information guides the plan of care, including both pharmacologic and nonpharmacologic therapies. Pharmacologic therapies include non-opioids, opioids, and adjuvant analgesics. Nonpharmacologic techniques include cognitive-behavioral strategies, such as distraction, guided imagery, education, and prayer, and physical measures, including heat, massage, bracing, and assistive devices. Health care professionals must be cognizant of the special pain-related needs of this fastest growing segment of the population.
Compiling a monolingual dictionary for native speakers.
P Hanks
Lexikos , 2010,
Abstract: This article gives a survey of the main issues confronting the compilers of monolingual dictionaries in the age of the Internet. Among others, it discusses the relationship between a lexical database and a monolingual dictionary, the role of corpus evidence, historical principles in lexicography vs. synchronic principles, the instability of word meaning, the need for full vocabulary coverage, principles of definition writing, the role of dictionaries in society, and the need for dictionaries to give guidance on matters of disputed word usage. It concludes with some questions about the future of dictionary publishing.
Compiling a Monolingual Dictionary for Native Speakers
Patrick Hanks
Lexikos , 2011, DOI: 10.5788/20-0-157
Abstract: ABSTRACT: This article gives a survey of the main issues confronting the compilers of monolingual dictionaries in the age of the Internet. Among others, it discusses the relationship between a lexical database and a monolingual dictionary, the role of corpus evidence, historical principles in lexicography vs. synchronic principles, the instability of word meaning, the need for full vocabulary coverage, principles of definition writing, the role of dictionaries in society, and the need for dictionaries to give guidance on matters of disputed word usage. It concludes with some questions about the future of dictionary publishing. OPSOMMING: Die samestelling van 'n eentalige woordeboek vir moedertaalsprekers. Hierdie artikel gee 'n oorsig van die hoofkwessies waarmee die samestellers van eentalige woordeboeke in die eeu van die Internet te kampe het. Dit bespreek onder andere die verhouding tussen 'n leksikale databasis en 'n eentalige woordeboek, die rol van korpusgetuienis, historiese beginsels vs sinchroniese beginsels in die leksikografie, die onstabiliteit van woordbetekenis, die noodsaak van 'n volledige woordeskatdekking, beginsels van die skryf van definisies, die rol van woordeboeke in die maatskappy, en die noodsaak vir woordeboeke om leiding te gee oor sake van betwiste woordgebruik. Dit sluit af met 'n aantal vrae oor die toekoms van die publikasie van woordeboeke. Sleutelwoorde: EENTALIGE WOORDEBOEKE, LEKSIKALE DATABASIS, WOORDEBOEKSTRUKTUUR, WOORDBETEKENIS, BETEKENISVERANDERING, GEBRUIK, GEBRUIKSAANTEKENINGE, HISTORIESE BEGINSELS VAN DIE LEKSIKOGRAFIE, SINCHRONIESE BEGINSELS VAN DIE LEKSIKOGRAFIE, REGISTER, SLANG, STANDAARDENGELS, WOORDESKATDEKKING, KONSEKWENSIE VAN VERSAMELINGS, FRASEOLOGIE, SINTAGMATIESE PATRONE, PROBLEME VAN KOMPOSISIONALITEIT, LINGUISTIESE PRESKRIPTIVISME, LEKSIKALE GETUIENIS
Measuring Bremsstrahlung Photons in 200 GeV p+p Collisions
Ali Hanks
Physics , 2007, DOI: 10.1142/S0218301307007659
Abstract: Direct photon production is an important observable in heavy ion collisions as photons are penetrating and therefore largely insensetive to final state effects that lead to jet quenching. Measurements of the fragmentation component to prompt photon yields in p+p and Au+Au collisions will provide both an important test of pQCD predictions and of predictions for modifications of this component in heavy ion collisions. By selecting photons associated with jets on the near side using hadron-photon correlations, fragmentation photons can be measured directly.
Temporal Reasoning About Uncertain Worlds
Steve Hanks
Computer Science , 2013,
Abstract: We present a program that manages a database of temporally scoped beliefs. The basic functionality of the system includes maintaining a network of constraints among time points, supporting a variety of fetches, mediating the application of causal rules, monitoring intervals of time for the addition of new facts, and managing data dependencies that keep the database consistent. At this level the system operates independent of any measure of belief or belief calculus. We provide an example of how an application program mi9ght use this functionality to implement a belief calculus.
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