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Search Results: 1 - 10 of 210351 matches for " Lyn Di Iorio Sandín "
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Latino rage: the life and work of ed rivera
Lyn Di Iorio Sandín
Centro Journal , 2002,
Abstract: In her personal reflection on-and critical reading of-Ed Rivera′s literary work, the author searches out an aspect of the fragmented Latino psyche. Because "Latino rage" expresses itself indirectly, it is overlooked not only by mainstream America, but also by Latinos themselves. The first part of her essay, "Egolessness," shows how Ed's humility which his friends saw as his defining trait masked anger. The second part of the essay, "The Saintly J baro and the Madwoman in the Boh o," demonstrates that the character of the madwoman in Ed′s novel Family Installments (1982) represents the repressed and angry aspect of Latino identity. "In Hiding," the final section of the essay, analyzes how the protagonist of Ed's novel rages against the passivity and humility, bred into him, by projecting them onto his father, whom he then angrily rejects. The essay holds up Ed Rivera′s life and work as a kind of mirror for Latinos. Like his novel s protagonist, Ed only partially expressed his rage, which tended to haunt his life and work, preventing him from fulfilling his brilliant promise as a writer.
Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility
Daniela Formicola, Andrea Aloia, Simone Sampaolo, Olimpia Farina, Daria Diodato, Lyn R Griffiths, Fernando Gianfrancesco, Giuseppe Di Iorio, Teresa Esposito
BMC Medical Genetics , 2010, DOI: 10.1186/1471-2350-11-103
Abstract: The association of polymorphic variants of GRIA1-GRIA4 genes which encode for the four subunits (GluR1-GluR4) of the alpha-amino-3- hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor for glutamate was tested in migraineurs with and without aura (MA and MO) and healthy controls.Two variants in the regulative regions of GRIA1 (rs2195450) and GRIA3 (rs3761555) genes resulted strongly associated with MA (P = 0.00002 and P = 0.0001, respectively), but not associated with MO, suggesting their role in cortical spreading depression. Whereas the rs548294 variant in GRIA1 gene showed association primarily with MO phenotype, supporting the hypothesis that MA and MO phenotypes could be genetically related. These variants modify binding sites for transcription factors altering the expression of GRIA1 and GRIA3 genes in different conditions.This study represents the first genetic evidence of a link between glutamate receptors and migraine.Migraine is a multifactorial disorder in which genetic factors play a relevant role in both predisposing and determining underlying mechanisms. Approaches to identified genes for monogenic subtypes migraine (e.g. Familial Hemiplegic Migraine - FHM) has been successful (CACNA1A, ATP1A2, SCN1A genes causing FMH 1, 2 and 3 respectively) [1-4]. Conversely, finding genes for the most frequent types of migraine (with and without aura) and defining their pathogenic role has proven much more difficult [5]. However, synaptic hyper-excitability has been invocated as one major pathogenic mechanism in both common and monogenic forms of migraine, and data from animal (experimental cortical spreading depression; c-fos protein expression at the trigeminal nucleus caudalis, plasma protein extravasations at level of dura-mater circulation, electrophysiological studies) [6,7] and human (assessment of glutamate concentration in plasma, platelets and cerebrospinal fluid in migraneurs vs. control, glutamate and migraine symptoms; glutamate and sensitization
The melatonergic system: effects on sleep and implications for the treatment of psychiatric disorders
De Berardis D, Acciavatti T, Di Iorio G, Corbo M, Serroni N, Campanella D, Di Emidio F, Piersanti M, Cavuto M, Martinotti G, Moschetta FS, Di Giannantonio M
ChronoPhysiology and Therapy , 2011, DOI: http://dx.doi.org/10.2147/CPT.S16972
Abstract: tonergic system: effects on sleep and implications for the treatment of psychiatric disorders Review (2147) Total Article Views Authors: De Berardis D, Acciavatti T, Di Iorio G, Corbo M, Serroni N, Campanella D, Di Emidio F, Piersanti M, Cavuto M, Martinotti G, Moschetta FS, Di Giannantonio M Published Date December 2011 Volume 2011:1 Pages 59 - 67 DOI: http://dx.doi.org/10.2147/CPT.S16972 Domenico De Berardis1,2, Tiziano Acciavatti1, Giuseppe Di Iorio1, Mariangela Corbo1, Nicola Serroni2, Daniela Campanella2, Fabiola Di Emidio2, Monica Piersanti3, Marilde Cavuto4, Giovanni Martinotti5, Francesco Saverio Moschetta2, Massimo Di Giannantonio1 1Department of Neurosciences and Imaging, Chair of Psychiatry, University “G. D'Annunzio”, Chieti; 2NHS, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital “G. Mazzini”; 3NHS, Pharmaceutical Service, Hospital “G. Mazzini”, Teramo; 4IASM, L'Aquila; 5Institute of Psychiatry, Catholic University Medical School, Rome, Italy Abstract: The circadian pacemaker or biological clock, located in the hypothalamic suprachiasmatic nucleus, is the generation site of circadian rhythms. The light/dark cycle is the circadian pacemaker's dominant synchronizing agent, though it is also influenced by neurotransmitters and the phase-shifting effects of various chemical and pharmacological components, of which melatonin (N-acetyl-5-methoxytryptamine) is the most well established. In recent years, melatonin and melatonin analogs have been commercialized in many countries, mainly with hypnotic purposes. A new compound, agomelatine, has been recently synthesized and studied. Among melatonin analogs, this drug possesses unique pharmacological and clinical features; it is an antagonist at 5-HT2B and 5-HT2C receptors and has well established antidepressant and anxiolytic properties. Agomelatine opens new perspectives in the chronobiotic treatment of depression. The purpose of the present review was to elucidate the effects of the melatonergic system on sleep and the implications for the treatment of psychiatric disorders.
Sistemática y distribución geográfica de Heterachthes flavicornis (Coleoptera: Cerambycidae)
Di Iorio, Osvaldo R.;
Iheringia. Série Zoologia , 2004, DOI: 10.1590/S0073-47212004000400009
Abstract: revision of 973 specimens of heterachthes flavicornis (thomson, 1865), mostly emerged from a same individual of different host plant species, shows that this species has a high phenotypical variation in the color of elytra, antennae and legs. this variability is not related to the geographical distribution or to the host plants. heterachthes flavicornis sexsignatus (thomson,1865), and heterachthes flavicornis bonariensis (thomson,1865) are considered into the synonymy of heterachthes flavicornis (thomson, 1865).
La Psicología Institucional en la Argentina: un acercamiento a la práctica
Universitas Psychologica , 2009,
Abstract: the current work presents the main aspects of the labor we usually develop as institutional psychologists, which is required by different consultant organizations. the originality of this consult is based on the nature of the consultant organization: a religious community. up to now, the lager number or the requested consults came from organizations within the education or health fields. the transmission of such experience becomes essential and enriching, bearing in mind the recent development of the institutional psychology field. besides, this transmission makes possible a feedback process to the research-action scope proposed here for the institutional phenomenon approach.
The paradox of our outcomes, and the use of qualitative methodology as a way to understand the realities of emerging countries  [PDF]
María Sandín Vázquez
Open Journal of Nursing (OJN) , 2012, DOI: 10.4236/ojn.2012.23034
Abstract: It is a fact that global health indicators in vulnerable populations are not improving, despite all resources concentrated in this area. Therefore, as a teacher and researcher in an international doctorate in Public Health, I took advantage of the contact with health professionals from Colombia, Peru and Bolivia (they were all my students) to try to better understand which factors may be affecting this paradox from the perspective of the major actors and therefore through a qualitative methodology. The main conclusion is that the health goals for the target populations (emerging and developing countries) are not the same as the goals for the planners and administrators of public health budgets. So if we want to improve health outcomes, it is time to let talk the people involved, and to let the administrators listen.
Lanthanum carbonate is not associated with QT interval modification in hemodialysis patients
Biagio Di Iorio, Emanuele Cucciniello
Clinical Pharmacology: Advances and Applications , 2010, DOI: http://dx.doi.org/10.2147/CPAA.S10218
Abstract: nthanum carbonate is not associated with QT interval modification in hemodialysis patients Original Research (2903) Total Article Views Authors: Biagio Di Iorio, Emanuele Cucciniello Published Date June 2010 Volume 2010:2 Pages 89 - 93 DOI: http://dx.doi.org/10.2147/CPAA.S10218 Biagio Di Iorio1, Emanuele Cucciniello1 1Unità Operativa Complessa di Nefrologia, PO “A Landolfi”, ASL Avellino – Solofra (AV), Italy Abstract: Lanthanum carbonate is an efficacious noncalcium, nonresin phosphate-binder that is being increasingly used in chronic kidney disease stage 5 (CKD-5) dialysis patients. Available evidence has indicated that QT interval changes correlate with mortality in healthy subjects and in dialysis patients. Experimental studies have suggested the possibility that lanthanum carbonate may produce prolongation of the QT interval. This is not accepted by other authors. There is no data confirming this in prospective clinical studies. The goal of this study was to verify the effect of lanthanum carbonate on the QT interval of the electrocardiogram (EKG) tracing. Material and methods: We studied 25 hemodialyzed patients. After a six-month run-in period, with aluminum-hydroxide, lanthanum carbonate was administered at increasing doses: 500 mg twice a day for week 1; 750 mg, twice daily during week 2; 1000 mg twice daily during week 3; and 1000 mg three times daily during week 4. EKGs were recorded on patients prior to and 3 hours following each dialysis treatment. Assessments were made of differences in body weight; systolic blood pressure; diastolic blood pressure; length of PR and QRS complex; heart rate; QT; QT-c; QT-d; and axis of wave P, QRS complex and T using lanthanum carbonate at increasing doses. Results: QT-c is before dialysis session during run-in 431 ± 20 msec with variation by -9 to + 1 msec (P = not significant [NS]) during lanthanum use; and 437 ± 25 msec after dialysis session with variation by -6 to -1 msec (P = NS) during lanthanum use. Any difference was observed during study among before and after dialysis session in QT-c (difference by 0.09 to 3.2%) (P = NS); and QT-d (difference by 8.6 to 9.1%) (P = NS). Conclusion: Our study shows that lanthanum carbonate administration, at increasing doses, did not modify the EKG parameters. This effect is observed both in predialysis and in postdialysis recordings. Further studies are necessary with more prolonged observations.
Semantic Publishing Challenge -- Assessing the Quality of Scientific Output
Christoph Lange,Angelo Di Iorio
Computer Science , 2014,
Abstract: Linked Open Datasets about scholarly publications enable the development and integration of sophisticated end-user services; however, richer datasets are still needed. The first goal of this Challenge was to investigate novel approaches to obtain such semantic data. In particular, we were seeking methods and tools to extract information from scholarly publications, to publish it as LOD, and to use queries over this LOD to assess quality. This year we focused on the quality of workshop proceedings, and of journal articles w.r.t. their citation network. A third, open task, asked to showcase how such semantic data could be exploited and how Semantic Web technologies could help in this emerging context.
Una nueva biología para una nueva sociedad
Máximo Sandín
Política y Sociedad , 2002, DOI: -
Abstract: Sin resumen
Welfare and Social Capital in Link ping, 1600–1620
Annika Sandén
Hygiea Internationalis : an Interdisciplinary Journal for the History of Public Health , 2008,
Abstract: This article deals with early seventeenth century local government, both the secular and religious, in order to present the concepts of ”the good society”, and the strategies that were used to achieve and retain this ideal. Most people were excluded from the ranks of decision-makers and had little or no possibility to influence the decisions that were made concerning their interests, such as the unwed mothers, hired hands and female servants. Still, those in society with a presumed low social capital also clearly valued the rituals of the town council and the church, and used the formal institutions to improve their conditions. The conclusion can thus be drawn that there was great confidence in the formal institutions and that they were used by more than those who belonged to the upper social strata. The local Swedish government of the town Link ping provided public resources which were beneficial to common people. This article illustrates how this functioned in practice.
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