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Search Results: 1 - 10 of 78366 matches for " Lulu Chen "
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The Mode Research of China’s Urban Land Assets Securitization  [PDF]
Lulu Chen, Danyu Chen
Open Journal of Social Sciences (JSS) , 2016, DOI: 10.4236/jss.2016.45001
Abstract:

Urban land purchasing and reserving system is an innovation in urban land usage in china, despite several financial problems with it. Land securitization is the best choice for carrying out the urban land reserve system. In the framework of urban land purchasing and reserving system, the urban land securitization was divided into two subunits, land real assets securitization and land credit assets securitization, according to whether the assets are entity or not. According to the types of securities, the former includes land bonds, investment funds and land trust plan three modes, while the latter includes balance-in mode, balance-out mode, quasi-off-balance-sheet mode and off-shore four modes. Discussion the aforementioned operation modes lead to suggestions for improving urban land securitization.

A novel procedure for absolute real-time quantification of gene expression patterns
Yingqing Lu, Lulu Xie, Jiani Chen
Plant Methods , 2012, DOI: 10.1186/1746-4811-8-9
Abstract: We propose a solution here with a novel procedure, which may accurately quantify the total cDNA conventionally prepared from a biological sample at the resolution of ~70 pg/μl, and reliably estimate the absolute numbers of transcripts in a picogram of cDNA. In comparison to the relative quantification, cDNA-based absolute (CBA) qPCR method is found to be more sensitive to gene expression variations caused by factors such as developmental and environmental variations. If the number of target transcript copies is further normalized by reference transcripts, cell-level variation pattern of the target gene expression may also be detectable during a developmental process, as observed here in cases across species (Ipomoea purpurea, Nicotiana benthamiana) and tissues (petals and leaves).By allowing direct comparisons of results across experiments, the new procedure opens a window to make inferences of gene expression patterns across a broad spectrum of living systems and tissues. Such comparisons are urgently needed for biological interpretations of gene expression variations in diverse cells.Being a key stage of functional realization of genome, gene expression has been increasingly quested for more details in various investigations [1-4]. Relative to still costly implementations of omics approaches, real-time quantitative polymerase chain reaction (qPCR) technique remains a top choice for comparison of gene expressions in cases of a small gene number but variable sample sizes because of the sensitivity of florophors, the efficiency of PCR [5], and the relatively low cost. Albeit having widespread usages in laboratories [6], qPCR may have some difficulties in interpretations of its results since gene expressions have been estimated as fold changes [7], which may be hard to compare across tissues and experiments without a common basis.Depending on the appropriate internal control (reference) genes, the relative qPCR method estimates fold change of expression difference bet
Isolation of plasma from whole blood using a microfludic chip in a continuous cross-flow
Xing Chen,DaFu Cui,LuLu Zhang
Chinese Science Bulletin , 2009, DOI: 10.1007/s11434-008-0551-7
Abstract: A novel microfluidic chip is developed for crossflow filtration plasma from the whole blood which is carried out in a continuous manner. This microfluidic chip was made of a silicon substrate sealed with a compound cover. The silicon substrate fabricated by micro-electro-mechanical system (MEMS) technology consisted of microposts array, microchannels and reservoirs. Then the silicon substrate was characterized by Scaning Electron Microscopy (SEM). The performance of the microfluidic chip was valued by the experiments of plasma isolation. During more than one hour of continuous blood infusion through the chip, there were no problems of jamming or clogging, and the plasma selectivity of 97.78% was achieved. Due to the chip’s simple structure and control mechanism with a continuous, real time operating manner, this microfluidic chip is easily expected to be integrated into micro total analytical system (μTAS) which will create a microanalysis system for point-of-care diagnostics.
Isolation of plasma from whole blood using a microfludic chip in a continuous cross-flow

Xing Chen,DaFu Cui,LuLu Zhang,

科学通报(英文版) , 2009,
Abstract: A novel microfluidic chip is developed for crossflow filtration plasma from the whole blood which is carried out in a continuous manner. This microfluidic chip was made of a silicon substrate sealed with a compound cover. The silicon substrate fabricated by micro-electro-mechanical system (MEMS) technology consisted of microposts array, microchannels and reservoirs. Then the silicon substrate was characterized by Scaning Electron Microscopy (SEM). The performance of the microfluidic chip was valued by the experiments of plasma isolation. During more than one hour of continuous blood infusion through the chip, there were no problems of jamming or clogging, and the plasma selectivity of 97.78% was achieved. Due to the chip’s simple structure and control mechanism with a continuous, real time operating manner, this microfluidic chip is easily expected to be integrated into micro total analytical system (μTAS) which will create a microanalysis system for point-of-care diagnostics. Supported by National Natural Science Foundation of China (Grant No. 60701019 and 605010200), National High Technology Research and Development Program of China (Grant No. 2006AAQ4Z355) and the Knowledge Innovation Program of Chinese Academy of Sciences
Analysis on Lung Cancer Survival from 2001 to 2007 in Qidong, China
Jian ZHU,Yonghui ZHANG,Yongsheng CHEN,Lulu DING
Chinese Journal of Lung Cancer , 2011,
Abstract: Background and objective Lung cancer is one of the most important malignancies in China. Survival rates of lung cancer on the population-based cancer registry for the years 2001-2007 in Qidong were analysed in order to provide the basis for the prognosis assessment and the control of this cancer. Methods Total 4,451 registered lung cancer cases was followed up to December 31st, 2009. Death certificates only (DCO) cases were excluded, leaving 4,382 cases for survival analysis. Cumulative observed survival rate (OS) and relative survival rate (RS) were calculated using Hakulinen’s method performed by the SURV 3.01 software developed at the Finnish Cancer Registry. Results The 1-, 3-, and 5-year OS rates were 23.73%, 11.89%, 10.01%, and the RS rates were 24.86%, 13.69%, 12.73%, respectively. The 1-, 3-, and 5-year RS of males vs females were 23.70% vs 27.89%, 12.58% vs 16.53%, and 11.73% vs 15.21%, respectively, with statisitically significant differences (χ2=13.77, P=0.032). RS of age groups of 15-34, 35-44, 45-54, 55-64, 65-74 and 75+ were 35.46%, 17.66%, 11.97%, 13.49%, 10.61%, 15.14%, respectively. Remarkable improvement could be seen for the 5-year RS in this setting if compared with that for the years 1972-2000. Conclusion The lung cancer survival outcomes in Qidong have been improved gradually for the past decades. Further measures on the prevention, diagnosis and treatment of lung cancer should be taken.
Use of the Local False Discovery Rate for Identification of Metabolic Biomarkers in Rat Urine Following Genkwa Flos-Induced Hepatotoxicity
Zuojing Li, Qing Li, Lulu Geng, Xiaohui Chen, Kaishun Bi
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0067451
Abstract: Metabolomics is concerned with characterizing the large number of metabolites present in a biological system using nuclear magnetic resonance (NMR) and HPLC/MS (high-performance liquid chromatography with mass spectrometry). Multivariate analysis is one of the most important tools for metabolic biomarker identification in metabolomic studies. However, analyzing the large-scale data sets acquired during metabolic fingerprinting is a major challenge. As a posterior probability that the features of interest are not affected, the local false discovery rate (LFDR) is a good interpretable measure. However, it is rarely used to when interrogating metabolic data to identify biomarkers. In this study, we employed the LFDR method to analyze HPLC/MS data acquired from a metabolomic study of metabolic changes in rat urine during hepatotoxicity induced by Genkwa flos (GF) treatment. The LFDR approach was successfully used to identify important rat urine metabolites altered by GF-stimulated hepatotoxicity. Compared with principle component analysis (PCA), LFDR is an interpretable measure and discovers more important metabolites in an HPLC/MS-based metabolomic study.
Density-dependent deformed relativistic Hartree-Bogoliubov theory in continuum
Ying Chen,Lulu Li,Haozhao Liang,Jie Meng
Physics , 2012, DOI: 10.1103/PhysRevC.85.067301
Abstract: The deformed relativistic Hartree-Bogoliubov theory in continuum with the density-dependent meson-nucleon couplings is developed. The formulism is briefly presented with the emphasis on handling the density-dependent couplings, meson fields, and potentials in axially deformed system with partial wave method. Taking the neutron-rich nucleus $^{38}$Mg as an example, the newly developed code is verified by the spherical relativistic continuum Hartree-Bogoliubov calculations, where only the spherical components of the densities are considered. When the deformation is included self-consistently, it is shown that the spherical components of density-dependent coupling strengths are dominant, while the contributions from low-order deformed components are not negligible.
Research on the Business Model of Insurance Companies Developing the Old-Age Care Communities—Taking China Life as an Example  [PDF]
Lulu Shi, Yifeng Wang
American Journal of Industrial and Business Management (AJIBM) , 2018, DOI: 10.4236/ajibm.2018.89129
Abstract: In recent years, Chinese population is tilted towards older people, and it is very limited for the state to invest in the elderly care facilities. Encouraged by the national policy, many insurance companies have embarked on constructing and operating the retirement community. However, the profit model of these insurance companies is not clear yet, and the return on investment is low, in which China Life is quite typical. Therefore, taking China Life as the research object and Osterwalder’s nine-element theory as a tool, the paper analyzes the existing business model of China Life developing the old-age care communities, and uses the business model canvas to reconstruct a new business model. Finally, the paper presents three management suggestions—that is—joint ventures with professional management institutions, innovative insurance products linked to pension communities, and the securitization of old-age assets. That will provide references for other insurance companies developing old-age care communities.
Impoverishment Risks in DIDR in Dar es Salaam City: The Case of Airport Expansion Project  [PDF]
Dawah Lulu Magembe-Mushi
Current Urban Studies (CUS) , 2018, DOI: 10.4236/cus.2018.64024
Abstract:
Contrary to the State’s rhetoric of inclusive governance, urban poor is excluded from planning for infrastructure development and resettlement processes, leading to a lack of understanding of their needs by the state resulting to their subsequent impoverishment after resettlement. This paper discusses impoverishment risks experienced by massive population resettlements from airport expansion project in Dar es Salaam City, Tanzania. The risks experienced were outcomes of procedures followed and policies/acts adopted in the implementation process. Literature on impoverishment risks experienced during displacement shows that poorly managed displacement processes and lack of adherence to policies and guidelines exposed the affected population to impoverishment risks for both short and long terms. The actualization of the risks depends on the preparedness of the project implementers or the government’s enforcement bodies in implementing the resettlement project. This paper draws empirical evidences obtained from studies conducted in 2014 and 2017. It discusses eleven impoverishment risks experienced by both the displaced and hosting communities at different periods and magnitudes. The paper argues that the displaced poor households have been further impoverished in the course of resettlement process as a result of limited attention to the risks of impoverishment both in policies and in local government practices. This paper realises that there is an urgent need for a resettlement policy which insists on participation of the affected communities that would eliminate impoverishment risks.
The Development of 7E Chromosome-Specific Molecular Markers for Thinopyrum elongatum Based on SLAF-seq Technology
Shiqiang Chen, Zefeng Huang, Yi Dai, Shuwen Qin, Yingying Gao, Lulu Zhang, Yong Gao, Jianmin Chen
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0065122
Abstract: Thinopyrum elongatum is an important relative of wheat, it is favored by many researchers for the disease resistant genes that exist in its E genome. Some studies have showed that the 7E chromosome of Th. elongatum contains resistance genes related to Fusarium head blight and wheat rust. Therefore, developing 7E chromosome-specific molecular markers linked to resistance genes will provide an important tool for exploring and using the resistant genes of Th. elongatum. In addition, it would greatly contribute in the effort to cultivate disease-resistant wheat varieties. Featured in high throughput, high-accuracy and low-cost, SLAF-seq technology has been widely used in molecular breeding, system evolution, and germplasm resource detection. Based on SLAF-seq, 518 specific fragments on the 7E chromosome of Th. elongatum were successfully amplified. A total of 135 primers were designed according to 135 randomly selected fragments, and 89 specific molecular markers of Th. elongatum were developed, with efficiencies up to 65.9%. These markers were all detected in a variety of materials, and they are all proved to be specific and stable. These markers can be used not only for detecting the 7E chromosome of Th. elongatum but also for providing an important theoretical and practical basis for wheat breeding by marker-assisted selection (MAS). This paper reports the first application of SLAF-seq technology with a high success rate in developing specific molecular markers for Th. elongatum, providing a strong case for the application of this new technology.
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