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Search Results: 1 - 10 of 240383 matches for " Luiz C. Correa "
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Altera??es bucais e cuidados orais no paciente transplantado de medula óssea
Luiz, Ana C.;Eduardo, Fernanda P.;Bezinelli, Letícia M.;Correa, Luciana;
Revista Brasileira de Hematologia e Hemoterapia , 2008, DOI: 10.1590/S1516-84842008000600012
Abstract: general care in bone marrow transplant (bmt) patients includes routine dental evaluations, which must be included in a multi-professional context. the oral cavity is a site that favors infections with high potential for consequent bacteremia and so infectious lesions must be treated or controlled by the dentist. the aim of this review is to discuss key questions in national and international literature with reference to oral inflammatory conditions of bmt patients, both those with predisposition to complications during the transplant and those that emerge during and after myelosuppression therapy. the literature emphasizes advanced periodontal disease, which is a chronic infectious condition that must be avoided or controlled during bmt, particularly because of the presence of s. viridans. the risk factors for oral mucositis, graft-versus-host disease (gvhd) and xerostomia have not yet been defined, particularly for oral mucositis and gvhd. promising alternatives in the treatment of oral mucositis, including cryotherapy, administration of growth factors and laser therapy, are emphatically mentioned. in children, craniofacial and dental alterations, particularly resulting from radiotherapy are relevant. the increased risk of caries is controversial, and among fungal and viral lesions, oral and oropharyngeal infections by candida and the herpes virus are identified as being of considerable clinical importance.
Amniotic membrane as a potent source of stem cells and a matrix for engineering heart tissue  [PDF]
Julio Cesar Francisco, Ricardo Correa Cunha, Rossana Baggio Simeoni, Luiz Cesar Guarita-Souza, Reginaldo Justino Ferreira, Ana Carolina Irioda, Carolina Maria C. Oliveira Souza, Garikipati Venkata Naga Srikanth, Soniya Nityanand, Juan Carlos Chachques, Katherine Athayde Teixeira de Carvalho
Journal of Biomedical Science and Engineering (JBiSE) , 2013, DOI: 10.4236/jbise.2013.612147

Existing therapies for the treatment of chronic heart failure still have some limitations and there is a pressing need for the development of new therapeutic modalities. The amniotic membrane has been used for the treatment of various diseases, such as conjunctive defects; however, the mechanisms behind its repair functions are still unclear. Regenerative medicine is seeking newer alternatives and among them, biomaterials have emerged in recent years for developing and manipulating molecules, cells, tissues or organs grown in laboratories in order to replace human body parts. Many such materials have been used for this purpose, either synthetically or biologically, in order to provide new medical devices. This review provides a wider view of the regeneration potential of the use of amniotic membrane as a potential biomaterial to facilitate the implementation of new research in surgical procedures. Amniotic membrane appears to be an alternative source of stem cells as well as an excellent biomaterial for cell-based therapeutic applications in engineering heart tissue.


Dengue: inquérito sorológico pós-epidêmico em zona urbana do Estado de S o Paulo (Brasil)
Lima Virgília L C de,Figueiredo Luiz T M,Correa F Heleno R,Leite Odair F
Revista de Saúde Pública , 1999,
Abstract: OBJETIVO: Avaliar o tamanho real da epidemia sobre dengue ocorrida na zona urbana do Município de Santa Bárbara D'Oeste, SP, Brasil, de abril a junho de 1995. MéTODOS: Foi realizado um inquérito soroepidemiológico pós-epidêmico 5 meses após o final da epidemia da dengue. Foram processados 1.113 soros através de amostragem aleatória domiciliar da popula o da cidade pesquisada. As taxas de infec o em diferentes partes da cidade foram relacionadas com os graus de infesta o por Aedes aegipty e com a quantidade de casos notificados durante a epidemia. RESULTADOS E CONCLUS ES: Foi encontrada varia o concomitante e diretamente proporcional entre as taxas de infec o pelo vírus da dengue, em diferentes partes da cidade, e os graus de infesta o domiciliar por Aedes aegipty, bem como em rela o ao número de casos notificados durante a epidemia. Encontrou-se prevalência de 630 por 100 mil habitantes, representando valor 15 vezes superior ao de incidência de casos confirmados laboratorialmente durante a epidemia. Através de compara o retrospectiva com dados de notifica o compulsória, observou-se que a vigilancia epidemiológica n o detectou a maioria das pessoas soro-reativas. Apesar disso, notificou grande quantidade de casos que n o eram de indivíduos com dengue, tipificando um valor preditivo positivo baixo (15,6%) para o diagnóstico clínico de dengue quando o resultado laboratorial (HAI) é tomado como padr o-ouro.
Taxa de cambio e pre?os de exporta??o no Brasil: avalia??o empírica dos coeficientes de pass-through setoriais
Correa, André Luiz;
Economia e Sociedade , 2012, DOI: 10.1590/S0104-06182012000100003
Abstract: this work empirically analyses the impacts that changes in exchange rates had on export prices in brazil, by sector, from 1995 to 2005. the main theoretical references take into account microeconomic aspects of international trade, such as market structure and the role of transnational corporations. pass-through coefficients were calculated, and factor analysis techniques were also applied with the aim of finding sector specific patterns. the findings suggest that the exchange rate pass-through to export prices of less complex goods, such as commodities, tends to be higher. regarding more complex goods, for example, automobiles and machinery, the results indicate reduced pass-through, notwithstanding the high pass-through to prices of electronics and other vehicles.
Resultados do tratamento cirúrgico na acromegalia com um único neurocirurgi?o e meta-análise cumulativa
Boeving, Anke;Borba, Luiz Alencar;Rodrigues, Adriane Maria;Orichowski, Elisa Brunner;Paz Filho, Gilberto Jorge da;Santos, Carlos M. Correa dos;Boguszewski, César Luiz;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2006, DOI: 10.1590/S0004-27302006000500009
Abstract: the aim of this retrospective study was to evaluate the results of transsphenoidal surgery in a group of patients with acromegaly who were operated by the same neurosurgeon. our results were compared to those from a cumulative meta-analysis of 10 series (1,632 patients) published between 1992-2005. we followed 28 patients (17m/11f; 44.1 ± 12.7 yr; 27 with macroadenomas; 86% being invasive) during 21.4 ± 17.6 months after treatment. patients were classified according to disease activity as follows: 1) controlled (cd): basal or mean gh < 2.5 ng/ml or nadir gh (ogtt) < 1 ng/ml and normal igf-1; 2) uncontrolled (ucd): basal or mean gh > 2.5 ng/ml or nadir gh > 1 ng/ml and elevated igf-1; 3) inadequately controlled (icd): normal gh and elevated igf-1 or elevated gh and normal igf-1. after surgery, gh levels decreased from 61.7 ± 101.1 ng/ml to 7.2 ± 13.7 ng/ml (p< 0.001) and mean igf-1 from 673.1 ± 257.7 ng/ml to 471.2 ± 285 ng/ml (p= 0.01). biochemical remission rate was 57% [10 (35.5%) patients with cd and 6 (21.5%) with icd], similar to the mean remission rate observed in the meta-analysis of surgical outcome of macroadenomas. seven of 28 patients were submitted to surgical re-intervention (4 had been previously operated elsewhere and 3 by our neurosurgeon), with cd observed in 5 (71.5%) on follow-up. cavernous sinuses invasion was more prevalent in ucd and icd, whereas infundibular stalk deviation occurred only in patients with ucd. remission rate was significantly higher in series where all surgical procedures were performed by the same surgeon (66% vs. 49%; p< 0.05). thus, the surgeon's experience significantly improves the surgical outcome in acromegaly, especially in patients harboring large and invasive tumors, and re-intervention performed by an experienced surgeon should be considered in the algorithms for clinical management of this disease.
Dissecting Major Signaling Pathways throughout the Development of Prostate Cancer
Henrique B. da Silva,Eduardo P. Amaral,Eduardo L. Nolasco,Nathalia C. de Victo,Rodrigo Atique,Carina C. Jank,Valesca Anschau,Luiz F. Zerbini,Ricardo G. Correa
Prostate Cancer , 2013, DOI: 10.1155/2013/920612
Abstract: Prostate cancer (PCa) is one of the most common malignancies found in males. The development of PCa involves several mutations in prostate epithelial cells, usually linked to developmental changes, such as enhanced resistance to apoptotic death, constitutive proliferation, and, in some cases, to differentiation into an androgen deprivation-resistant phenotype, leading to the appearance of castration-resistant PCa (CRPCa), which leads to a poor prognosis in patients. In this review, we summarize recent findings concerning the main deregulations into signaling pathways that will lead to the development of PCa and/or CRPCa. Key mutations in some pathway molecules are often linked to a higher prevalence of PCa, by directly affecting the respective cascade and, in some cases, by deregulating a cross-talk node or junction along the pathways. We also discuss the possible environmental and nonenvironmental inducers for these mutations, as well as the potential therapeutic strategies targeting these signaling pathways. A better understanding of how some risk factors induce deregulation of these signaling pathways, as well as how these deregulated pathways affect the development of PCa and CRPCa, will further help in the development of new treatments and prevention strategies for this disease. 1. Introduction The long-term ineffectiveness of current treatments for prostate cancer (PCa) has spurred an increasing interest in understanding the molecular mechanisms that underlie PCa tumorigenesis [1]. Currently, PCa is considered the most common nonmelanoma neoplasia among men [2–4]. According to the current trends in population growth, the incidence of PCa will exceed 1.7 million new cases by 2030 [5]. In the United States, nearly 2.8 million men are potentially living with this condition, and approximately 240,000 new cases were diagnosed in 2012 [3]. PCa predominately affects elderly men with higher incidence [6], and it is more prevalent in Western countries [7], where the average life expectation is over 75 years old. In developing countries like Brazil, PCa has recently surpassed the population incidence of breast cancer, and it has become the most common tumor malignancy, with approximately 50,000 new cases occurring per year [4, 5]. Yet, there is a considerable heterogeneity in the mortality rates and incidence among different countries, probably due to the variable penetrance of some risk factors such as age, race, genetics (family history), diet and environmental factors [8], and also behavioral factors, like frequent consumption of dairy products and meat
A língua portuguesa no contexto do magistério de 1o e 2o graus
Manoel Luiz Gon?alves Correa
Alfa : Revista de Linguística , 2001,
Abstract: O presente artigo procura tra ar um panorama do trabalho do professor no magistério de 1o e 2o graus, buscando mostrar em que condi es ele toma contato com as contribui es vindas de outros centros irradiadores de conhecimento, especialmente com aquelas vindas da universidade. Estabelecido o contexto no qual o professor atua e no qual toma contato com essas contribui es, o artigo trata, ao mesmo tempo, da confus o corrente entre o uso da express o "Língua Portuguesa" como disciplina curricular e o seu uso como objeto de estudo, e do descompasso entre as concep es por professores de 1o e 2o graus e na circunstancia de ser concebido por pesquisadores.
Bovine pericardium retail preserved in glutaraldehyde and used as a vascular patch
Wladimir F Saporito, Adílson C Pires, Sérgio H Cardoso, Jo?o A Correa, Luiz de Abreu, Vitor E Valenti, Luciano MR Miller, Eduardo Colombari
BMC Surgery , 2011, DOI: 10.1186/1471-2482-11-37
Abstract: Fourteen young pigs, six females and eight males, weighting 10.3 - 18.4 kg were used in our study. We implanted three remnants in each pig, two in the abdominal aorta and one was juxtaposed to the peritoneum. The smooth face (SF) and rough face (RF) of each remnant were implanted turned to the vessel inner portion and one remnant was juxtaposed to the peritoneum. The animals were sacrificed in 4.5 - 8 months after surgery (75 - 109 kg). The remnants were assessed for aorta wall, fibroses formation in inner apposition and calcification related to the face turned to the vessel inner portion.The rough face showed a lower dilatation level compared to the face implanted in adjacent aorta. There was no difference between intensity and/or incidence of graft calcification when the superficies were compared. The bovine pericardium preserved in glutaraldehyde did not show alterations in its structure when implanted with different faces turned to the inner portion of vessel.When turned to the inner portion of the vessel, the rough face of the remnant presented a lower dilatation in relation to the adjacent aorta and a better quality of endothelium layer and did not show a difference between intensity and/or incidence of graft calcification.The use of biological tissues such as vascular substitutes dates back to early days of cardiovascular surgery, when an autologous vein was used as an arterial substitute. The use of prostheses and orthoses have become necessary to the development of cardiovascular surgery, since the correction of complex congenital heart disease and valvular heart disease require the use of these materials as vascular substitutes [1]. Carpentier et al [2], with the introduction of glutaraldehyde at low concentration for the preservation of biological tissues, started a new period by introducing the concept of bioprosthesis, which despite being a biological tissue, it loses its antigenicity, does not induce the formation of antibodies and produces the disrupt
Monosomy 7 in donor cell-derived leukemia after bone marrow transplantation for severe aplastic anemia: report of a new case and review of the literature
Otero, Luize;Souza, Daiane Correa de;Tavares, Rita de Cássia;Gomes, Bernadete Evangelho;Padilha, Telma Fran?a;Bouzas, Luiz Fernando;Fernandez, Teresa de Souza;Abdelhay, Eliana;
Genetics and Molecular Biology , 2012, DOI: 10.1590/S1415-47572012005000056
Abstract: monosomy 7 arises as a recurrent chromosome aberration in donor cell leukemia after hematopoietic stem cell transplantation. we report a new case of donor cell leukemia with monosomy 7 following hla-identical allogenic bone marrow transplantation for severe aplastic anemia (saa). the male patient received a bone marrow graft from his sister, and monosomy 7 was detected only in the xx donor cells, 34 months after transplantation. the patient's bone marrow microenvironment may have played a role in the leukemic transformation of the donor hematopoietic cells.
Evaluation of efficacy of preservatives associated with Achillea millefolium L. extract against Bacillus subtilis
Salvagnini, Luiz E.;Migliato, Ketylin F.;Isaac, Vera L.B.;Correa, Marcos A.;Salgado, Hérida R.N.;Pietro, Rosemeire C.L.R.;
Brazilian Journal of Microbiology , 2006, DOI: 10.1590/S1517-83822006000100014
Abstract: the antimicrobial efficacy of three preservatives used in cosmetic formulations was evaluated. phenova? and imidazolidinyl urea inhibited the growth of bacillus subtilis when added to leaf extract of achillea millefolium l., whereas 0.2% nipagin?/ nipasol? in propylene glycol did not.
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