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Search Results: 1 - 10 of 355794 matches for " Luis Fernándo; González J. "
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Efecto del acibenzolar-s-metil sobre el desarrollo de la virosis causada por potyvirus en tomate de árbol
Mejía A.,Diana Marcela; Rodas G.,Erika Isabel; Pati?o H.,Luis Fernándo; González J.,Elena Paola;
Agronomía Colombiana , 2009,
Abstract: tree tomato virosis has become a major constraint on the production and quality of this fruit in colombia. the effect of resistance inductor acibenzolar-s-methyl- asm (boost?) on virus incidence and severity was tested by applying a 0.08% solution of this commercial product on healthy plants also inoculated with an extract of infected ones. asm applications were carried out every 20 days. the plants treated with the product prior to inoculation showed a 7 day delay in manifesting infection symptoms, and a considerable reduction in disease severity. out of this same group of treatments, the one in which asm was applied twice after inoculation, determined viral incidence to be reduced by 50%, when compared to non-resistance-induced plants (100%). the same incidence pattern was found through the area under the disease progress curve (audpc) procedure. although the potyvirus was detected through a das - elisa test, it showed no significant concentration differences among the treatments.
Efecto del acibenzolar-s-metil sobre el desarrollo de la virosis causada por potyvirus en tomate de árbol
Mejía A. Diana Marcela,Rodas G. Erika Isabel,Pati?o H. Luis Fernándo,González J. Elena Paola
Agronomía Colombiana , 2009,
Abstract: El principal limitante del cultivo de tomate de árbol en Colombia es el ataque de virus, el cual reduce la producción y calidad de la fruta. En condiciones de invernadero se evaluó el efecto del inductor de resistencia Acibenzolar-S-metil- ASM (Boost ) sobre la incidencia y severidad de la virosis en plantas inoculadas con extracto de hojas naturalmente infectadas con virus, mediante aplicación foliar de 0,08% de producto comercial por planta cada 20 días. La incidencia de la virosis se redujo en 50% cuando el inductor se aplicó antes de la inoculación con el virus, seguido de dos aplicaciones adicionales de ASM, comparado con 100% de incidencia en las plantas inoculadas solo con el extracto de plantas infectadas con el virus, tendencia encontrada también en la curva de desarrollo de la enfermedad. Se observó un retraso de 7 días en la aparición de síntomas cuando se aplicó el inductor antes de la inoculación así como se observó una reducción significativa en el grado de severidad de la enfermedad. El potyvirus fue detectado mediante la prueba ELISA; sin embargo, no se encontraron diferencias estadísticas significativas en su concentración entre los diferentes tratamientos.
Hematuria de origen papilar o medular: entidad de difícil diagnóstico
González Enguita,Carmen; Gómez Mu?oz,Jesús; Martín Vivas,Cristina; López Martín,Leticia; Susanibar Napuri,Luis Fernándo; Alexandro,Simona; Caramelo Díaz,Carlos; Vela Navarrete,Remigio;
Archivos Espa?oles de Urología (Ed. impresa) , 2008, DOI: 10.4321/S0004-06142008000500002
Abstract: objectives: renal haemangiomas of renal papillary or medullar origin are a difficult diagnosis entity, being one of the most frequent processes of chronic episodes of hematuria, secondary to benign disease, mainly in young patients (1). the objective of this paper is to show the difficulty of this diagnosis and the need to suspect it in cases with clinical history similar to the ones described in these cases. methods: we report 4 cases of spontaneous hematuria of renal origin, with clinical presentation as renal colic, from the historical case series of the fundacion jimenez díaz - capio, the last two from the years 2005-6. we present the diagnostic and therapeutic methodology employed, including angio-ct and flexible ureterorenoscopy (urs) as well as various treatment options. results: hematuria was identified as "essential" when any relation with tumor or lithiasic pathologies was ruled out, and of renal origin when the source was clearly pointed. we interpreted it was related to angiomas or microangiomas of papillary or medullar origin. in one case, the vascular malformation was interpreted as an arterial venous fistula (avf) at that level. hematuria stopped spontaneously in two cases after exploratory urs. the eldest historical case required surgical expiration of the caliceal structures. conclusion: years ago, following the professional development of urology as speciality, conventional surgery was carried out in all these cases, of very difficult diagnosis, with a very small number of cases undergoing a conservative approach based on the examination of renal cavities trying to observe and find the bleeding point. most cases underwent complete or partial nephrectomy. currently, the possibility of exploration of all renal cavities with the flexible ureterorenoscope enables a better diagnosis of the lesions and a more conservative treatment. the ultimate diagnosis of renal papillary angioma is the pathologic diagnosis, without pathognomonic data in the imaging te
Prevalencia en México de la infección y el estado de portador de la hepatitis B en adultos
Valdespino,José Luis; Conde-González,Carlos J; Olaiz-Fernández,Gustavo; Palma,Oswaldo; Sepúlveda,Jaime;
Salud Pública de México , 2007, DOI: 10.1590/S0036-36342007000900012
Abstract: objective: to estimate the prevalence of chronic hepatitis b infection and carrier status in mexico; to analyze the frequency and distribution of hepatitis b markers in relation to the demographic and geographic variables and to identify risk factors. materials and methods: a total of 12 014 sera samples from the 2000 national health survey that were randomly selected for anti-hbc and hbsag were studied. the sera were collected between november 1999 and june 2000 on a national level. results: seroprevalence for anti-hbc and hbsag were 3.3% (ci 95%: 2.8-3.9) and 0.21% (0.11-0.37), respectively. odds ratios adjusted by age for anti-hbc were: 15.3 for subjects 50 to 59 years old as compared with adults less than 29 years of age; 2.6 for residents in the southern region of the country as compared with residents in the central region; 4.6 for laborers as compared with business owners; 2.1 for women having had stillbirths; and 1.7 for adults having initiated sexual relations before 25 years of age. conclusion: the epidemiological pattern for hepatitis b in mexico is lower than the data worldwide. nevertheless, it is of concern that 1.7 million mexicans have suffered from the infection caused by this virus and 107 000 suffer from a chronic carrier status.
Frecuencia de ametropías Frequency of ametropias
Luis Curbelo Cunill,Juan R Hernández Silva,Enrique J Machado Fernández,Carmen M Padilla González
Revista Cubana de Oftalmolog?-a , 2005,
Abstract: Se realizó un estudio con una muestra aleatoria de 9 513 pacientes seleccionados (19 026 ojos) que presentaban ametropías y que asistieron a consulta de cirugía refractiva en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer"; donde se encontró una mayor frecuencia de éstas en el sexo femenino con predominio en las edades entre los 21 y los 30 a os. El astigmatismo miópico compuesto fue la ametropía más frecuente en la muestra, con diferencias de género a favor del sexo femenino; el astigmatismo hipermetrópico simple fue la única ametropía que no mostró diferencias entre los grupos de edades. Existió una correlación lineal positiva entre la edad y la intensidad de la hipermetropía y miopía en el grupo de pacientes entre los 18 y los 39 a os. Hubo predominio de las miopías y las hipermetropías ligeras y moderadas. Entre las ametropías esféricas un 36, 8 % de ojos obtuvo un rango de severidad que excedía los criterios quirúrgicos. No se encontró relación entre la magnitud del cilindro y la edad de los casos estudiados. Los astigmatismos directo, oblicuo y oblicuo directo demostraron mayor frecuencia en la muestra, donde prevaleció el ojo derecho en el tipo directo e indirecto, mientras que en el ojo izquierdo predominaron el oblicuo directo y el oblicuo inverso. La anisometropía fue poco frecuente en la muestra y alcanzó solamente el 2,1 % del total de pacientes emétropes y predominó en el grupo de 31 a 35 a A descriptive study was conducted with a randomized sample of 9 513 patients selected (19 026 eyes) that presented ametropias and that received attention at the department of refractive surgery in "Ramón Pando Ferrer" Cuban Institute of Ophthalmlogy. Ametropias were more frequent among women aged 21-30. The compound myopic astigmatism was the commonest ametropia in the sample, with difference of gender in favor of females. The simple hypermetropic astigmatism was the only ametropia that did not show differences among the age groups. There was a positive lineal correlation between age and the intensity of hypermetropia and myopia in the group of patientes aged 18-39. It was observed a predominance of myopias and mild and moderate hypermetropias. In the spheric ametropias, 36.8 % of eyes had a severity range that exceeded the surgical criteria. No relation was found between the magnitude of the cylinder and the age of the studied cases. The direct, the oblique and the direct oblique astigmatisms showed a higher frequency in the sample, where the right eye prevailed in the direct and indirect type. The direct oblique and the inverse oblique predomi
Glucagonoma syndrome: a case report
Pablo Castro, Alberto de León, Jose Trancón, Paloma Martínez, Jose A álvarez Pérez, Jose C Fernández Fernández, Carmen M García Bernardo, Luis Serra, Juan J González González
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-402
Abstract: We present the case of a 70-year-old Caucasian woman with glucagonoma syndrome due to an alpha-cell tumor located in the tail of the pancreas, successfully treated with surgical resection.Clinicians should be aware of the unusual initial manifestations of glucagonoma. Early diagnosis allows complete surgical resection of the neoplasm and provides the only chance of a cure.A glucagonoma is a slow-growing alpha-cell tumor of the pancreatic islets of Langerhans. It may appear as a benign and localized alpha-cell adenoma but at least 50% of cases will have metastatic disease when diagnosed [1]. Glucagonomas can be associated with other tumors in Multiple Endocrine Neoplasia syndrome 1 (MEN 1), but this association is rare and comprises no more than 3% of glucagonomas. Even though glucagonomas related to MEN 1 syndrome probably carry a better prognosis due to early recognition through periodic screening visits, 80% are malignant and frequently spread to the liver [2]. Glucagonoma syndrome is a rare paraneoplastic phenomenon, with an estimated incidence of one in 20 million, characterized by necrolytic migratory erythema (NME), hyperglucagonemia, diabetes mellitus, anemia, weight loss, glossitis, cheilitis, steatorrhea, diarrhea, venous thrombosis and neuropsychiatric disturbances in the setting of a glucagon-producing alpha-cell tumor of the pancreas [3]. The most common features of this syndrome are weight loss, NME and diabetes mellitus [4]. Of these, NME presents as the hallmark clinical sign of glucagonoma syndrome [3]. Its early recognition allows a prompt diagnosis of the tumor and leads to a better prognosis. Surgery is the optimal treatment for a glucagonoma. We present a patient with glucagonoma syndrome due to a well circumscribed alpha-cell tumor of the pancreas, in which surgical removal of the tumor by distal pancreatectomy with splenectomy led to resolution of the cutaneous and systemic features.A 70-year-old Caucasian woman was referred to our Department o
Relationship between morphological features and kinetic patterns of enhancement of the dynamic breast magnetic resonance imaging and clinico-pathological and biological factors in invasive breast cancer
Oscar Fernández-Guinea, Alejandro Andicoechea, Luis O González, Salomé González-Reyes, Antonio M Merino, Luis C Hernández, Alfonso López-Mu?iz, Paz García-Pravia, Francisco J Vizoso
BMC Cancer , 2010, DOI: 10.1186/1471-2407-10-8
Abstract: Dynamic MRI parameters of 68 invasive breast carcinomas were investigated. We also analyzed microvessel density (MVD), estrogen and progesterone receptor status, and expression of p53, HER2, ki67, VEGFR-1 and 2.Homogeneous enhancement was significantly associated with smaller tumor size (T1: < 2 cm) (p = 0.015). Tumors with irregular or spiculated margins had a significantly higher MVD than tumors with smooth margins (p = 0.038). Tumors showing a maximum enhancement peak at two minutes, or longer, after injecting the contrast, had a significantly higher MVD count than those which reached this point sooner (p = 0.012). The percentage of tumors with vascular invasion or high mitotic index was significantly higher among those showing a low percentage (≤ 150%) of maximum enhancement before two minutes than among those ones showing a high percentage (>150%) of enhancement rate (p = 0.016 and p = 0.03, respectively). However, there was a significant and positive association between the mitotic index and the peak of maximum intensity (p = 0.036). Peritumor inflammation was significantly associated with washout curve type III (p = 0.042).Variations in the early phase of dynamic MRI seem to be associated with parameters indicatives of tumor aggressiveness in breast cancer.Magnetic resonance imaging (MRI) plays an important role in the evaluation of the extent of breast cancer by revealing multifocal tumor growth in patients who are candidates for conservative breast surgery [1]. MRI permits us to explorer two concepts: First, we are able to analyze the morphologic characteristics of the lesions with high spatial resolution, such as the margin morphology (smooth, irregular or spiculated) or the internal architecture of the tumors (represented as internal mass enhancement: homogeneous, heterogeneous or rim enhancement) [1-3]. Second, we can also obtain dynamic data derived from the kinetic patterns of lesion enhancement after the administration of contrast material [4]. These
Patrón de ingesta en un grupo de pacientes con síndrome de intestino irritable: relación de la ingesta de fibra con los síntomas
Aller,R.; Luis,D. A. de; Izaola,O.; La Calle,F.; Olmo,L. del; Fernández,L.; Arranz,T.; González Hernández,J. M.;
Anales de Medicina Interna , 2004, DOI: 10.4321/S0212-71992004001200002
Abstract: objectives: the aim of our study was to evaluate the oral dietary intake of a group of patients with irritable bowel syndrome and to compate with international recommendations. patients and methods: a total of 53 patients with irritable bowel syndrome was enrolled in a non-propabilistic sample. patiens were diagnose with roma ii criteria. in all patients were determined, weight, height, body mass index, dietary intake of 3 days and a symptoms scoring system. results: the average age of 53 patients was 45.67±13.6 years with a distribution of sex (22 males/31 females). caloric intakes was righ in absolut terms and corrected by weight. distribution of calories was 41.5% of carbohidrates, a 19.8% of proteins, and a 38.7% of lipids, showing a high intake of lipids and low of carbohidrates. a low intake of vitamin a and d was detected. high intake of vitamin b12, vitamin c and niacine was observed. a low intake of calcium, magnesium, yodo and zinc was detected. intake of soluble fiber was lower than insoluble fiber (1.46±0.74 g/day) (19%) vs 6.21±2.67 g/day (71%). intake of fiber corrected by calories was low 4.5±1.2 g/1000 calories. in correlation analysis, insoluble fiber (r=0.46; p < 0.05) and soluble fiber (r=0.42; p < 0.05) were inverse correlated with general symptoms. conclusions: patients with irritable bowel syndrome showed a desviation of mineral and vitamin dietary . fiber intake is low, a correlation between fiber intake and general symptoms was detected.
Estudio descriptivo del comienzo de la diabetes mellitus tipo 1 y sus familiares de primer grado
Luis,D. A. de; Alonso Fernández,M.; González Sagrado,M.; Aller,R.; Izaola,O.; Martín Gil,J.; Terroba,M. C.; Cuéllar,L.;
Anales de Medicina Interna , 2004, DOI: 10.4321/S0212-71992004000800004
Abstract: background: few information about descriptive studies of autoimmunity in diabetes mellitus type 1 onset patients and family exist. the aim of our study was to analyze clinical and biochemical parameters of onset diabetes mellitus type 1 patients and first degree families. patients and methods: forty seven onset diabetes mellitus type 1 patients and 148 first degree families were studied, between january 1999 and december 2002, in the west area of valladolid. in all cases and families an anthropometric study and biochemical determination with autoimmunity levels were performed. results: average age in onset diabetes mellitus type 1 patients was 16.09 (9.36) years, without differences between males (32 cases, 68%) and females (15 cases, 32%), with an incidence of 4.66 cases/100,000 habs./year. average values of peroxidase antibodies (antipto) and glutamic descarboxilase antibodies (antigad) were higher in diabetic patients than in families. no differences were detected in insulin antibodies (iaa) and tiroglobuline antibodies (antitg). no correlation was detected between anti tpo and anti pancreas. autoantibodies did not influence in glycemic control. average dose of nph insulin and regular insulin were 27.58 (13.88) ui/d y 3.05 (4.90) ui/d, respectively. conclusions: average age of onset diabetes mellitus type 1 patients was similar than other studies, with a high frequency of males. values of antigad y antitpo were higher in diabetic patients than families. no correlation between autoimmunity and glycemic control was detected.
Inhibidores de la enzima conversora de angiotensina: Revisión de estudios multicéntricos
González García,Verónica Marlene; Fernández Machín,Luis Manuel; Ruibal León,Antonio J.; Durán Torres,Gilberto;
Revista Cubana de Medicina , 2002,
Abstract: a literature review of the angiotensin inhibitors was made. a brief historical review was made and the mechanisms of actions, the effects at different levels and the secondary reactions of these inhibitors were reviewed. different multicenter studies that have been carried out with this group of drugs were analyzed, in which we found out that such drugs favorably affect morbidity and mortality of patients with heart failure, their effects are higher in those patients with advanced degree of heart failure and that high doses should be used according to tolerance. although it is said that these inhibitors are not exchangeable, the reviewed literature did not show the superiority of one drug over the others for certain disease and/or group of patients.
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