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Search Results: 1 - 10 of 5286 matches for " Luciana Castaneda "
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Fernanda Guimar?es de Andrade,Luciana Castaneda,Paula Mello,Heitor Silveira
Perspectivas Online : Biológicas e Saúde , 2012,
Abstract: O acesso a informa es sobre funcionalidade vem sendo uma prioridade no tratamento da Doen a deParkinson. A Classifica o Internacional de Funcionalidade (CIF) é uma ferramenta com grandeaplicabilidade para a orienta o dos processos de funcionalidade. O objetivo e verificar aspectos daFuncionalidade e a Fatores Ambientais em pacientes com DP. Metodologia: a amostra foi composta por 11individuos com DP. A média de idade foi 66(±10) anos e tempo médio de doen a 7,6(±64) anos. Foiaplicado um questionário com as op es de resposta sim/n o para verificar limita es na atividade, restri oa participa o e facilitadores dos fatores ambientais do Checklist da CIF. A tarefa de andar foi relatada comolimita o por 91% dos indivíduos, seguido de realiza o de tarefas domésticas (73%); restri o na recrea oe lazer foi verificada em 73% da amostra. Todos os individuos apontaram como facilitador as atitudesindividuais dos profissionais de saúde e 91% o apoio dos profissionais de saúde. Considerando asimplica es da DP nos aspectos motores, nas atividades de vida diária e participa o social, os resultadosmostram que a CIF parece ter boa capacidade e sensibilidade para abordar aspectos da funcionalidade emindivíduos com a doen a. Em virtude do tamanho pequeno da amostra, futuros estudos s o necessários paraextrapola o dos resultados.
People and their Pasts edited by Paul Ashton and Hilda Kean
Christopher Castaneda
Public History Review , 2009,
Potential Impact of a New GEM-based Detector on CMS Triggering
A. Castaneda
Physics , 2013,
Abstract: With the increases in the LHC instantaneous luminosity, maintaining effective triggering and avoiding dead time will become especially challenging. As the sensitivity of many physics studies, depends critically on the ability to maintain relatively low muon momentum thresholds, the identification of potential improvements in triggering is particularly important. The addition of a new muon detector to the existing CMS muon system in the very forward region allows for a substantial improvement in the performance of muon triggering. Integration of the new detector and the existing Cathode Strip Chamber system can improve the muon trigger momentum resolution due to an increase in the lever arm for the measurement of the muon bending angle.
Exotic Higgs Searches in CMS
A. Castaneda
Physics , 2013,
Abstract: We present some of the most recent results from the CMS Collaboration on searches for Higgs-like particles in models beyond the Standard Model. Several rare and exotic decay modes of the Higgs boson are explored. The results of the searches are relevant for establishing whether the 125 GeV particle observed in Higgs boson searches at the LHC has the properties expected for a Standard Model Higgs boson.
Skeletal muscle sodium glucose co-transporters in older adults with type 2 diabetes undergoing resistance training
Francisco Castaneda, Jennifer E. Layne, Carmen Castaneda
International Journal of Medical Sciences , 2006,
Abstract: We examined the expression of the sodium-dependent glucose co-transporter system (hSGLT3) in skeletal muscle of Hispanic older adults with type 2 diabetes. Subjects (65±8 yr) were randomized to resistance training (3x/wk, n=13) or standard of care (controls, n=5) for 16 weeks. Skeletal muscle hSGLT3 and GLUT4 mRNA transcript levels were determined by real time RT-PCR. hSGLT3 transcripts increased by a factor of ten following resistance training compared to control subjects (0.10, P=0.03). There were no differences in GLUT4 mRNA expression levels between groups. Protein expression levels of these transporters were confirmed by immunohistochemistry and Western blotting. hSGLT3 after resistance exercise was found not to be co-localized with the nicotinic acetylcholine receptor. The change in hSGLT3 transcript levels in the vastus lateralis muscle was positively correlated with glucose uptake, as measured by the change in muscle glycogen stores (r=0.53, P=0.02); and with exercise intensity, as measured by the change in muscle strength (r=0.73, P=0.001). Group assignment was be the only independent predictor of hSGLT3 transcript levels, explaining 68% of its variability (P=0.01). Our data show that hSGLT3, but not GLTU4, expression was enhanced in skeletal muscle after 16 weeks of resistance training. This finding suggests that hSGLT3, an insulin-independent glucose transporter, is activated with exercise and it may play a significant role in glycemic control with muscle contraction. The hSGLT3 exact mechanism is not well understood and requires further investigation. However its functional significance regarding a reduction of glucose toxicity and improvement of insulin resistance is the subject of ongoing research.
Review: Andrew Carnegie, by David Nasaw
Castaneda, Christopher J.
Journal of Historical Biography , 2009,
New applications of pseudoanalytic function theory to the Dirac equation
Antonio Castaneda,Vladislav V. Kravchenko
Mathematics , 2005, DOI: 10.1088/0305-4470/38/42/003
Abstract: In the present work we establish a simple relation between the Dirac equation with a scalar and an electromagnetic potentials in a two-dimensional case and a pair of decoupled Vekua equations. In general these Vekua equations are bicomplex. However we show that the whole theory of pseudoanalytic functions without modifications can be applied to these equations under a certain not restrictive condition. As an example we formulate the similarity principle which is the central reason why a pseudoanalytic function and as a consequence a spinor field depending on two space variables share many of the properties of analytic functions. One of the surprising consequences of the established relation with pseudoanalytic functions consists in the following result. Consider the Dirac equation with a scalar potential depending on one variable with fixed energy and mass. In general this equation cannot be solved explicitly even if one looks for wave functions of one variable. Nevertheless for such Dirac equation we obtain an algorithmically simple procedure for constructing in explicit form a complete system of exact solutions (depending on two variables). These solutions generalize the system of powers of z in complex analysis and are called formal powers. With their aid any regular solution of the Dirac equation can be represented by its Taylor series in formal powers.
Developing Standards for Language Teacher Education Programs in Indonesia: Professionalizing or Losing in Complexity?
Luciana Luciana
TEFLIN Journal , 2004,
Abstract: Setting standards for language teacher education programs, materials, and evaluation sparks some hope in attempts to improve the quality of the programs. Yet, this very fact augmented by my examination of ten language teacher education programs in Java, Bali, and Lampung (FKIP and PGRI) triggers a critical look at the idea of standard development. In particular, I would like to explore whether it can lead to a better professionalism or we are just lost in the complexity of the standardization itself. This paper consists of four sections. Departing from an overview of language teacher education programs in Indonesia and the theoretical foundations, some major problems in this area are identified. Following this, the discussion is focused on the idea of standard development for language teacher education programs in Indonesia. Eventually, some suggestions are put forth to highlight the need for establishing coherent curriculum framework bridging the two realms of language teacher education and school milieu as well as providing learners with knowledge base that enables them to cope with complex demands of school settings and more essentially, to act as an agent in the social change process.
Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways
Francisco Castaneda, Sigrid Rosin-Steiner
International Journal of Medical Sciences , 2006,
Abstract: As we previously demonstrated in human hepatocellular carcinoma (HepG2) cells, ethanol at low concentration triggers the Fas apoptotic pathway. However, its role in other intracellular signaling pathways remains unknown. Therefore, the aim of the present study was to evaluate the role of low concentration of ethanol on different intracellular signaling pathways. For this purpose, HepG2 cells were treated with 1 mM ethanol for 10 min and the phosphorylation state of protein kinases was determined. In addition, the mRNA levels of transcription factors and genes associated with the Fas apoptotic pathway were determined. Our data demonstrated that ethanol-induced phosphorylation of protein kinases modulates both anti-apoptotic and pro-apoptotic mechanisms in HepG2 cells. Pro-apoptosis resulted mainly from the strong inhibition of the G-protein couple receptor signaling pathway. Moreover, the signal transduction initiated by ethanol-induced protein kinases phosphorylation lead to increased expression of the transcription factors with subsequent expression of genes associated with the Fas apoptotic pathway (Fas receptor, Fas ligand, FADD and caspase 8). These results indicate that low concentration of ethanol exert their effect by predominant activation of pro-apoptotic events that can be divided in two phases. An early phase characterized by a rapid transient effect on protein kinases phosphorylation, after 10 min exposure, with subsequent increased expression of transcription factors for up to 6 hr. This early phase is followed by a second phase associated with increased gene expression that began after 6 hr and persisted for more than 24 hr. This information provided a novel insight into the mechanisms of action of ethanol (1mM) in human hepatocellular carcinoma cells.
Long-Term Efficacy and Safety of Botulinum Toxin Injections in Dystonia
Juan Ramirez-Castaneda,Joseph Jankovic
Toxins , 2013, DOI: 10.3390/toxins5020249
Abstract: Local chemodenervation with botulinum toxin (BoNT) injections to relax abnormally contracting muscles has been shown to be an effective and well-tolerated treatment in a variety of movement disorders and other neurological and non-neurological disorders. Despite almost 30 years of therapeutic use, there are only few studies of patients treated with BoNT injections over long period of time. These published data clearly support the conclusion that BoNT not only provides safe and effective symptomatic relief of dystonia but also long-term benefit and possibly even favorably modifying the natural history of this disease. The adverse events associated with chronic, periodic exposure to BoNT injections are generally minor and self-limiting. With the chronic use of BoNT and an expanding list of therapeutic indications, there is a need to carefully examine the existing data on the long-term efficacy and safety of BoNT. In this review we will highlight some of the aspects of long-term effects of BoNT, including efficacy, safety, and immunogenicity.
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