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Search Results: 1 - 10 of 5859 matches for " Lorna Gregory "
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Representation embeddings, interpretation functors and controlled wild algebras
Lorna Gregory,Mike Prest
Mathematics , 2014,
Abstract: We establish a number of results which say, roughly, that interpretation functors preserve algebraic complexity. First we show that representation embeddings between categories of modules of finite-dimensional algebras induce embeddings of lattices of pp formulas and hence are non-decreasing on Krull-Gabriel dimension and uniserial dimension. A consequence is that the category of modules of any wild finite-dimensional algebra has width $\infty$ and hence, if the algebra is countable, there is a superdecomposable pure-injective representation. It is conjectured that a stronger result is true: that a representation embedding from ${\rm Mod}\mbox{-}S$ to ${\rm Mod}\mbox{-}R$ admits an inverse interpretation functor from its image and hence that, in this case, ${\rm Mod}\mbox{-}R$ interprets ${\rm Mod}\mbox{-}S$. This would imply, for instance, that every wild category of modules interprets the (undecidable) word problem for (semi)groups. We show that the conjecture holds for finitely controlled representation embeddings. Finally we prove that if $R,S$ are finite dimensional algebras over an algebraically closed field and $I:{\rm Mod}\mbox{-}R\rightarrow{\rm Mod}\mbox{-}S$ is an interpretation functor such that the smallest definable subcategory containing the image of $I$ is the whole of ${\rm Mod}\mbox{-}S$ then, if $R$ is tame, so is $S$ and similarly, if $R$ is domestic, then $S$ also is domestic.
Identifying microRNA/mRNA dysregulations in ovarian cancer
Gregory D Miles, Michael Seiler, Lorna Rodriguez, Gunaretnam Rajagopal, Gyan Bhanot
BMC Research Notes , 2012, DOI: 10.1186/1756-0500-5-164
Abstract: TCGA Microarray data was normalized and samples whose class labels (tumour or normal) were ambiguous with respect to consensus ensemble K-Means clustering were removed. Significantly anti-correlated and correlated genes/microRNA differentially expressed between tumour and normal samples were identified. TargetScan was used to identify gene targets of microRNA.We identified novel microRNA/mRNA mechanisms in ovarian cancer. For example, the expression level of RAD51AP1 was found to be strongly anti-correlated with the expression of hsa-miR-140-3p, which was significantly down-regulated in the tumour samples. The anti-correlation signature was present separately in the tumour and normal samples, suggesting a direct causal dysregulation of RAD51AP1 by hsa-miR-140-3p in the ovary. Other pairs of potentially biological relevance include: hsa-miR-145/E2F3, hsa-miR-139-5p/TOP2A, and hsa-miR-133a/GCLC. We also identified sets of positively correlated microRNA/mRNA pairs that are most likely result from indirect regulatory mechanisms.Our findings identify novel microRNA/mRNA relationships that can be verified experimentally. We identify both generic microRNA/mRNA regulation mechanisms in the ovary as well as specific microRNA/mRNA controls which are turned on or off in ovarian tumours. Our results suggest that the disease process uses specific mechanisms which may be significant for their utility as early detection biomarkers or in the development of microRNA therapies in treating ovarian cancers. The positively correlated microRNA/mRNA pairs suggest the existence of novel regulatory mechanisms that proceed via intermediate states (indirect regulation) in ovarian tumorigenesis.Ovarian cancers have a high mortality rate and few treatment options and the failure rate is high [1]. In spite of significant advances in detection and effort to reduce recurrence rates, the five year survival rate has remained relatively unchanged for over 50 years [2].The Cancer Genome Atlas (TCGA) [
Categorising Example Sentences in Dictionaries for Research Purposes Kategorisering van voorbeeldsinne in woordeboeke vir navorsingsdoeleindes.
Lorna Hiles
Lexikos , 2012, DOI: 10.5788/21-1-46
Abstract: Examples in dictionaries come in many different forms. They may be sentences or phrases. They may be corpus-based or made up by the lexicographer. They may contain the lemma in its uninflected form or they may contain an inflection of the lemma. In some dictionaries the function of examples is to provide contextual support to the meaning of the headword, and in others the grammatical support that they provide is more important. While there is literature on the usefulness of examples, and on whether examples should be corpus-based or not, there is very little on what makes one example more useful than another. I have set out to find out what sort of examples South African school users identify as most helpful. In this article, I look at whether examples in five South African school dictionaries do provide suitable contextual or grammatical support. I have constructed a table to classify example sentences according to different criteria. I filled in this table with randomly selected words and their examples which have been taken from five different South African school dictionaries. The goal of this research is to present characteristics of examples in a way that makes them easier to analyse and compare. This should help lexicographers in future dictionaries check whether they have written or selected the best possible examples for their users' needs. Voorbeelde in woordeboeke verskyn in baie verskillende vorme. Hulle kan sinne of frases wees. Hulle kan korpusgebaseer of deur die leksikograaf geskep wees. Hulle kan die lemma in sy onverbo vorm bevat of hulle kan 'n verbuiging van die lemma bevat. In sommige woordeboeke is die funksie van voorbeelde om kontekstuele steun vir die betekenis van die trefwoord te verskaf, in ander is die grammatiese steun wat hulle verskaf, belangriker. Terwyl daar literatuur oor die nuttigheid van voorbeelde bestaan, en of voorbeelde korpusgebaseer moet wees of nie, bestaan daar baie min oor wat een voorbeeld nuttiger maak as 'n ander. Ek het begin om uit te vind watter soort voorbeelde Suid-Afrikaanse skoolgebruikers aanwys as die nuttigste. In hierdie artikel kyk ek of voorbeelde in vyf Suid-Afrikaanse skoolwoordeboeke wel geskikte kontekstuele of grammatiese steun verskaf. Ek het 'n tabel opgestel om voorbeeldsinne volgens verskillende maatstawwe te klassifiseer. Ek het hierdie tabel voltooi met lukraak gekose woorde en hul voorbeelde wat uit vyf verskillende Suid-Afrikaanse skoolwoordeboeke geneem is. Die doel van hierdie navorsing is om eienskappe van voorbeelde op 'n manier aan te bied wat dit makliker maak om hulle
Lorna Hughes
Research in Learning Technology , 1996, DOI: 10.3402/rlt.v4i1.9960
Abstract: In these days of research-assessment exercises and cost-cutting measures, if you have not arranged beforehand for the proceedings of your conference to be published, you can expect fewer proposals for papers from experts at the cutting edge of their subject. Many departments will not normally fund attendance at conferences, especially those held abroad, unless there is a concrete outcome which can be added to the departmental publications list. This is why, over the last few years, we have seen such an increase in the number of edited conference papers. Unfortunately (and I certainly do not include this current issue of ALT-J in this statement, because the selection procedure has been really quite cruel), many of these proceedings are of low overall quality. The is no doubt partly because once your paper has been accepted for the conference, you want as much of a guarantee of publication as possible before you turn up and give it, and conference organisers are thus under pressure not to give the copper-bottomed guarantee they cannot of course give, but at least to keep you, as far as possible, in Promise Land. This situation tends to lead to diluted proceedings.
The flying Africans: extent and strength of the myth in the Americas
Lorna McDaniel
Nieuwe West-Indische Gids , 1990,
Abstract: [First paragraph] The theme of human aerial flight permeates the mythology of Black America. Examples of the metaphor are found in major musical genres, myths and poetry in Black cultures that span the Caribbean and southern North America, embracing generations to testify to the depth of the cosmological and conscious projection of systems of flight escape and homeland return. While the theme of human flight does not occur in any significant proportion in West African mythology related themes of transformation and pursuit do appear. However, in African thought, witches and spirits possess the power of flight; a flight that can be blocked by the use of salt. The belief in spirit flight, ubiquitous in the Black diaspor of the New World, parallels that in African thought, but in the New World it is enlarged to include humans as possessors of the capability of flight.
The Concept of Truth Regime
Lorna Weir
The Canadian Journal of Sociology , 2008,
Abstract: “Truth regime” is a much used but little theorized concept, with the Foucauldian literature presupposing that truth in modernity is uniformly scientific/quasi-scientific and enhances power. I argue that the forms of truth characteristic of our present are wider than Foucault recognized, their relations to power more various, and their historicity more complex. The truth regime of advanced modernity is characterized by multiple, irreducible truth formulae that co-exist and sometimes vie for dominance. A truth formula stabilizes a network of elements: a relation between representation and presentation (words and things), truth and non-truth, and the place of the subject in discourse. Our contemporary truth regime comprises radically heterogeneous truthful knowledges – science, governance, religion/politics, and common culture – that have distinct histories and relations to power.
Assessment - A Powerful Lever for Learning
Lorna Earl
Brock Education : a Journal of Educational Research and Practice , 2010,
Abstract: Classroom assessment practices have been part of schooling for hundreds of years. There are, however, new findings about the nature of learning and about the roles that assessment can play in enhancing learning for all students. This essay provides a brief history of the changing role of assessment in schooling, describes three different purposes for assessment and foreshadows some implications that shifting to a more differentiated view of assessment can have for policy, practice and research.
A critical cluster analysis of 44 indicators of author-level performance
Lorna Wildgaard
Computer Science , 2015,
Abstract: This paper explores the relationship between author-level bibliometric indicators and the researchers the "measure", exemplified across five academic seniorities and four disciplines. Using cluster methodology, the disciplinary and seniority appropriateness of author-level indicators is examined. Publication and citation data for 741 researchers across Astronomy, Environmental Science, Philosophy and Public Health was collected in Web of Science (WoS). Forty-four indicators of individual performance were computed using the data. A two-step cluster analysis using IBM SPSS version 22 was performed, followed by a risk analysis and ordinal logistic regression to explore cluster membership. Indicator scores were contextualized using the individual researcher's curriculum vitae. Four different clusters based on indicator scores ranked researchers as low, middle, high and extremely high performers. The results show that different indicators were appropriate in demarcating ranked performance in different disciplines. In Astronomy the h2 indicator, sum pp top prop in Environmental Science, Q2 in Philosophy and e-index in Public Health. The regression and odds analysis showed individual level indicator scores were primarily dependent on the number of years since the researcher's first publication registered in WoS, number of publications and number of citations. Seniority classification was secondary therefore no seniority appropriate indicators were confidently identified. Cluster methodology proved useful in identifying disciplinary appropriate indicators providing the preliminary data preparation was thorough but needed to be supplemented by other analyses to validate the results. A general disconnection between the performance of the researcher on their curriculum vitae and the performance of the researcher based on bibliometric indicators was observed.
地球学报 , 2010, DOI: 10.3975/cagsb.2010.s1.31
Abstract: AlthoughtheNaturalHistoryMuseum’spterosaurcollectionisnotlarge(approximately1060specimens),itisofgreathistoricalandscientificimportance.Mostofthematerialisfigured,andseveralholotypesarehousedhere.PterosaursfromUKlocalitiesarewellrepresented,butforeignmaterialisalsopresentasoriginalspecimensandashighqualitycasts.
Adopting Course Book To Meet The Exploration of the Expectations of the Syllabus and the Students Local Needs.A Focus on Teacher Practise.
Africa International journal of management education and Governance , 2017, DOI: -
Abstract: With the rapid English language teaching development, more and more books have made their way into the market and choosing the right course book to meet the expectations of the syllabus and the students’ local needs is becoming more and more important at all levels of English language teaching. This paper examined ways of adapting course books by teachers of English language in secondary school in Kenya, so as to meet the expectations of the syllabus and the students’ needs. With effort from text book writers, English language teaching researchers and classroom teachers, course book adaption has evolved from ad hoc to systematic action. Although most classroom teachers may not be involved in the production of the syllabus and the text books, they have the responsibility for course book adaptation. Reference to the term course book has expanded from books to all materials used in English language teaching. It has evolved into a great variety of resources used in language classrooms such as audio cassettes, videos, CD-ROMs, flash cards and other authentic materials such as newspapers, photographs, advertisements and radio/TV programmes. The findings of this paper revealed that, for a course book to help a student learn language, it has to be perceived as relevant to the student’s needs and provide new learning experiences that connect with the student’s previous knowledge. It recommended that, for effective teaching/learning to take place successfully, teachers should play an active role in adapting course books. They should throw away the so called course books in traditional pedagogy and adapt authentic materials in their practices.
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