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Search Results: 1 - 10 of 22143 matches for " Lopes Marta Heloísa "
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Vacina inativada contra a hepatite A: revis?o da literatura e considera??es sobre seu uso
Santos, Márcio Vieira;Lopes, Marta Heloísa;
Revista da Sociedade Brasileira de Medicina Tropical , 1997, DOI: 10.1590/S0037-86821997000200010
Abstract: a new, safe, highly immunogenic and probably long term effective inactivated hepatitis a virus vaccine has been licensed for clinical use. clinical trials in developed countries have demonstrated its efficacy in preventing hepatitis a in high risk groups, such as travelers to regions where hav infection is endemic and day care children and staff, its efficacy in postexposure conditions and in community outbreaks. the authors review the basic and changing features of the disease and its epidemiology in especific geographical regions trying to elucidate its use in the control of the disease in developing countries, especially in brazil. taking in consideration its efficacy, safety and immunogenicity, the inactivated hepatitis a vaccine may be of extreme value in terms of individual protection. because this vaccine is so new, there are no formal recomendations for its use in developing countries, and appropriate public health use of hepatitis a vaccine requires up-to-date epidemiological information.
Vacina inativada contra a hepatite A: revis o da literatura e considera es sobre seu uso
Santos Márcio Vieira,Lopes Marta Heloísa
Revista da Sociedade Brasileira de Medicina Tropical , 1997,
Abstract: O desenvolvimento, licenciamento e comercializa o recentes de uma vacina inativada contra a hepatite A (VIHA) têm possibilitado a obten o de imuniza o ativa, segura e provavelmente duradoura contra essa doen a. Estudos conduzidos em países desenvolvidos demonstram sua utilidade clínica na preven o da hepatite A (HA) em viajantes susceptíveis que se dirigem a áreas de alta endemicidade, em crian as pré-escolares e trabalhadores de creches, além de avaliar o uso pós-exposi o e em em surtos epidêmicos. Os autores enfocam aspectos epidemiológicos atuais da hepatite A em diferentes regi es visando, através do conhecimento da epidemiologia da doen a, esclarecer a utilidade que a VIHA teria no controle dessa doen a nos países em desenvolvimento, especialmente no Brasil. Com base na sua eficácia, seguran a e imunogenicidade, a VIHA se mostra de extremo valor a nível de prote o individual. Porém, devido ao pouco tempo de uso clínico desta vacina, n o encontramos disponíveis recomenda es formais para o seu uso nos países em desenvolvimento, especialmente a nível de Saúde Pública. Dados epidemiológicos atualizados sobre a HA nas diversas regi es brasileiras s o essenciais para o desenvolvimento de uma estratégia racional de imuniza o.
Occurrence of early adverse events after vaccination against influenza at a brazilian reference center
Lopes, Marta Heloísa;Mascheretti, Melissa;Franco, Marilia Miranda;Vasconcelos, Ricardo;Gutierrez, Eliana Battaggia;
Clinics , 2008, DOI: 10.1590/S1807-59322008000100005
Abstract: introduction: since 1999, the ministry of health in brazil has conducted campaigns of vaccination against influenza targeted towards the elderly, chronically-diseased people and health care workers. the vaccine against influenza is associated with adverse events of minor importance. objective: to investigate the early adverse events related to the vaccine against influenza. casuistics and methods: one hundred and ninety seven elderly individuals and health care workers vaccinated against influenza were included. an inquiry regarding adverse events related to the vaccine was applied seven days after the vaccination. results: local adverse events were reported by 32.5% and systemic effects by 26.4% of the vaccinated subjects. pain in the region of the injection, headache, myalgia, malaise, and coryza were more frequent in the workers than in the elderly (p<0.05). there was no statistically significant difference in the occurrence of fever. conclusions: the belief of part of the population that credits frequent and uncomfortable adverse events to the vaccine was not confirmed. the subjective adverse events were more frequent in the health care workers, which can influence, in a negative way, the disclosure of the benefits of this vaccine due to their role as opinion makers.
Effectiveness of influenza vaccination in elderly outpatients in S?o Paulo city, Brazil
GUTIERREZ, Eliana Battaggia;LI, Ho Yeh;SANTOS, Ana Catarina De Seixas;LOPES, Marta Heloísa;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2001, DOI: 10.1590/S0036-46652001000600003
Abstract: to investigate the effectiveness of the influenza vaccine in a population of elderly outpatients, we compared the occurrence and frequency of influenza like illness (ili), respiratory illness and hospitalization in vaccinated and non-vaccinated subjects. all the outcomes were clinically defined. the two groups were similar with respect to demographics, health situation and habits. the influenza vaccine contributed to the protection of the elderly investigated, since the vaccinated subjects referred a significantly lower number of ili than the non-vaccinated. there is a need for more studies about the effectiveness of the influenza vaccine in our country in elderly and other groups of our population.
Effectiveness of influenza vaccination in elderly outpatients in S o Paulo city, Brazil
GUTIERREZ Eliana Battaggia,LI Ho Yeh,SANTOS Ana Catarina De Seixas,LOPES Marta Heloísa
Revista do Instituto de Medicina Tropical de S?o Paulo , 2001,
Abstract: To investigate the effectiveness of the influenza vaccine in a population of elderly outpatients, we compared the occurrence and frequency of influenza like illness (ILI), respiratory illness and hospitalization in vaccinated and non-vaccinated subjects. All the outcomes were clinically defined. The two groups were similar with respect to demographics, health situation and habits. The influenza vaccine contributed to the protection of the elderly investigated, since the vaccinated subjects referred a significantly lower number of ILI than the non-vaccinated. There is a need for more studies about the effectiveness of the influenza vaccine in our country in elderly and other groups of our population.
Comparison of indirect immunofluorescence test for measles antibodies with haemagglutination inhibition and plaque neutralization tests
Souza, Vanda Akico Ueda Fick de;Pannuti, Cláudio Sérgio;Godoy, Cid Vieira Franco de;Albrecht, Paul;Lopes, Marta Heloísa;Mendon?a, Jo?o da Silva;
Revista do Instituto de Medicina Tropical de S?o Paulo , 1990, DOI: 10.1590/S0036-46651990000500009
Abstract: indirect immunofluorescence (ifa), plaque reduction neutralization (prn) and haemagglutination inhibition (hi) tests for measles antibodies were carried out in 197 sera obtained from umbilical cord and vaccinated children. the ifa was also applied to blood samples collected with filter paper. ifa results demonstrated that the test is relatively simple to perform, with good reproducibility for different antigen lots. good correlation was obtained between ifa, prn and hi antibody titers. better correlation was demonstrated with ifa and prn than with hi and prn tests. sensitivity of ifa in detecting antibody was less effective than prn, however more effective than hi using rhesus monkey red blood cells. prn antibody titers over 100 were detected by ifa but not by hi (9.7% with negative results). ifa may be of considerable practical use and able to substitute hi in seroepidemiological surveys and to evaluate vaccine efficacy. it also can be simplified by employing filter paper collected samples.
Measles vaccination: influence of age on its efficacy
Lopes, Marta Heloísa;Mendon?a, Jo?o Silva de;Pannuti, Cláudio Sérgio;Albrecht, Paul;Biancalana, Maria Lúcia Neves;Mantese, Orlando César;Correa, José Fábio;Amato Neto, Vicente;
Revista do Instituto de Medicina Tropical de S?o Paulo , 1989, DOI: 10.1590/S0036-46651989000500005
Abstract: the authors compare the serologic efficacy and the clinical protection afforded by three different measles vaccination schemes in adequately nourished children in s?o paulo city, brazil. two hundred forty two children were divided into three groups. group a, comprising 117 children who had received the vaccine before 12 months of age and a second dose at 12 months of age or more. group b, comprising 46 children who had received only one dose, before 12 months of age. group c, comprising 79 children who had received only one dose, at 12 months of age or more. the geometric mean titer of antibodies in group a was 790.1; in group b, 251.1; and in group c, 550.3. there was no statistically significant difference between groups a and c. the exposure to the measles virus was probably similar in all groups, and the children in groups a and c had similar chances of acquiring the disease after vaccination whereas in group b the chances were higher when compared to the other two groups. the results obtained in this study favor the use, in developing countries, of a vaccination program against measles that includes an early first dose at eight months of age and revaccination after 12 months of age.
AVALIA??O SENSORIAL DE VINHAS RIESLING ITáLICO NACIONAIS UTILIZANDO PERFIL LIVRE
BENASSI, Marta de Toledo;DAMáSIO, Maria Helena;CECCHI, Heloísa Máscia;
Ciência e Tecnologia de Alimentos , 1998, DOI: 10.1590/S0101-20611998000300003
Abstract: there is a large bibliography on descriptive sensory analysis of wines. free-choice profiling, a new descriptive sensory technique, was applied to develop a profile with respect to appearance, aroma and taste for seven brazilian welchriesling wines. twelve panelists, without experience with the technique, were selected using triangular tests. the grid method was used to obtain the list of descriptors. the number of attributes developed for each judge vary from seven to thirteen. generalized procrustes analysis were applied to the data. during fifteen days, fifteen sessions were realized: two to select the assessors, four to develop the terminology, two to check the score sheets and seven to evaluate the wines (balanced incomplete block design). it was observed good discrimination between the samples. wines were differentiated mainly by taste attributes (acid, "astringent", alcoholic, sweet and fruity), correlated with dimension 1 (25% of variance), and one appearance attribute (yellow color), associated with dimension 2 (9% of variance).
Funda??o de assistência integral à saúde/Hospital Sofia Feldman: uma experiência de administra??o flexível?
Alves, Marília;Carvalho, Heloísa de;Amaral, Marta Araújo;
Revista Latino-Americana de Enfermagem , 1999, DOI: 10.1590/S0104-11691999000400002
Abstract: the purpose of the present study was to verify the correspondence between the administrative experience of the hospital "sofia feldman" and the theory on flexible management proposed by motta (1991) and médici & silva (1993). it also described innovation elements for institutional integration with the community, such as the substitute mother, ombudsman and systematic voluntary work, done by community association of friends and users of sofia feldman hospital. data were collected with a semi-structured interview, applied to employees of differents sectors, aiming at knowing their perception about the administrative model used. the flexible administration characteristics of the hospital were evidenced, however authors found elements of classical administration.
AVALIA O SENSORIAL DE VINHAS RIESLING ITáLICO NACIONAIS UTILIZANDO PERFIL LIVRE
BENASSI Marta de Toledo,DAMáSIO Maria Helena,CECCHI Heloísa Máscia
Ciência e Tecnologia de Alimentos , 1998,
Abstract: A literatura cita um grande número de trabalhos envolvendo análise sensorial descritiva para vinhos. Perfil Livre, uma nova técnica descritiva, foi utilizado na caracteriza o em termos de aparência, sabor e aroma para sete amostras de vinhos brancos Riesling Itálico nacionais. Doze provadores, sem experiência anterior com a técnica, foram selecionados utilizando-se teste triangular. Para o levantamento de atributos foi empregado o método rede. O número de atributos levantados por provador variou de sete a treze. Utilizou-se a análise Procrustes Generalizada para tratamento dos dados. Durante quinze dias, foram realizadas quinze sess es, sendo duas para a sele o de provadores, quatro para o levantamento de atributos, duas para checar a ficha e sete para avalia o das amostras (blocos incompletos balanceados). Foi obtida boa discrimina o entre as amostras. Os vinhos foram separados com base em atributos de sabor (doce, frutado, ácido, "adstringente" e alcoólico), correlacionados com a dimens o 1 (25% da variancia), e um atributo de aparência (cor amarela), correlacionado com a dimens o 2 (9% da variancia).
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