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Search Results: 1 - 10 of 98 matches for " Lodi "
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Aggregation modes of anionic oxacarbocyanines with polycations in solution and in ESAMs
Andrea Lodi,Glauco Ponterini
International Journal of Photoenergy , 2006, DOI: 10.1155/ijp/2006/72383
Abstract: Interaction of oxacarbocyanines D-G with three polycations in aqueous solutions results in the formation of two types of likely small, distorted aggregates rather than the classical J aggregates. On the contrary, the latter are extensively and almost exclusively obtained in electrostatically self-assembled multilayers (ESAMs) prepared by alternate polycation/dye adsorption on quartz substrates. The J-aggregate growth on supported polycations is qualitatively shared by the four cyanines, a fact that reveals the crucial role of the double anionic substitutions on the dyes. On the other hand, films with D and E, which are known to have a stronger tendency to give dimers in water, exhibit higher J-band intensities and stability upon drying relative to those with F and G. Based on these observations, we suggest that energetic factors associated with cofacial dye/dye van der Waals interactions, ultimately related with the degree of planarity of the conjugated chromophores, may still play a major role in controlling aggregation equilibria in these complex systems.
Plurilingüismo e surdez: uma leitura bakhtiniana da história da educa??o dos surdos
Lodi, Ana Claudia Balieiro;
Educa??o e Pesquisa , 2005, DOI: 10.1590/S1517-97022005000300006
Abstract: the history of the education of deaf people is marked by conflict and controversy. it is observed that although the discussions carried out in the last five centuries make reference to education, the questions related to the educational sphere itself have never been emphasized. in other words, the teaching methods and the practices were subjected to the linguistic factor and approached with the purpose of describing and sustaining the defense of the development of oral or sign language. in the present article discussions shall be made from the viewpoint of bakhtin's theory, considering the main facts occurred in the history of the education of deaf people throughout the centuries. the various ideologies that have permeated the discourses about deafness will be explained, as will the historical struggle between the brazilian sign language (libras) and the portuguese language, focusing on the processes determining the lack of incentive, for more than a century, to the use of libras in the educational processes of deaf people. the consequences of this history for our current reality will be pointed out. lastly, a brief exposition of a research carried out by the author will be made, pointing to processes that suggest that a transformation of the education of and by deaf people should be made, particularly with regard to the development of the subjects as readers, giving elements to the definition of new studies in the educational sphere.
A leitura em segunda língua: práticas de linguagem constitutivas da(s) subjetividade(s) de um grupo de surdos adultos
Lodi, Ana Claudia;
Cadernos CEDES , 2006, DOI: 10.1590/S0101-32622006000200005
Abstract: based on the realization of bilingual reading workshops, this work discusses some aspects that constitute the subjectivity(ies) of a group of adult deaf. grounded on discursive interactions in brazilian sign language (libras), such space allowed a transformation of the social places assumed by the subjects because it permitted the establishment of dialogs between life stories and the different social relationships constructed within and by the group. assuming that subjectivity is always relative, determined by the various looks of the others and constructed in distinct social-ideological places and times, and that it constitutes a plural event discursively marked, in which the self completes itself dialogically in its relationship(s) to the others, the discussions presented in this study highlight the need to rethink the educational spaces as loci of discursive interactions and thus of transformation and constitution of the subjects.
Uma leitura enunciativa da língua brasileira de sinais: o gênero contos de fadas
Lodi, Ana Claudia Balieiro;
DELTA: Documenta??o de Estudos em Lingüística Teórica e Aplicada , 2004, DOI: 10.1590/S0102-44502004000200005
Abstract: this article refers to an initial study of the discoursive processes of the brazilian sign language (libras) in the fairy tales genre under the light of the enunciative theory of bakhtin. current analysis data, although in its early stages, pointed out some relevant discoursive aspects about libras, mainly those related to the constitution of its interdiscursive dynamic. it refers to the understanding of how the different voices present in the text are built, how they differ in their compositional aspects, how they assimilate the discourse of other, and how they interrelate to each other and to the full context regarding the approach of the theme.
Magnetic Resonance Spectroscopy Detectable Metabolomic Fingerprint of Response to Antineoplastic Treatment
Alessia Lodi, Sabrina M. Ronen
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0026155
Abstract: Targeted therapeutic approaches are increasingly being implemented in the clinic, but early detection of response frequently presents a challenge as many new therapies lead to inhibition of tumor growth rather than tumor shrinkage. Development of novel non-invasive methods to monitor response to treatment is therefore needed. Magnetic resonance spectroscopy (MRS) and magnetic resonance spectroscopic imaging are non-invasive imaging methods that can be employed to monitor metabolism, and previous studies indicate that these methods can be useful for monitoring the metabolic consequences of treatment that are associated with early drug target modulation. However, single-metabolite biomarkers are often not specific to a particular therapy. Here we used an unbiased 1H MRS-based metabolomics approach to investigate the overall metabolic consequences of treatment with the phosphoinositide 3-kinase inhibitor LY294002 and the heat shock protein 90 inhibitor 17AAG in prostate and breast cancer cell lines. LY294002 treatment resulted in decreased intracellular lactate, alanine fumarate, phosphocholine and glutathione. Following 17AAG treatment, decreased intracellular lactate, alanine, fumarate and glutamine were also observed but phosphocholine accumulated in every case. Furthermore, citrate, which is typically observed in normal prostate tissue but not in tumors, increased following 17AAG treatment in prostate cells. This approach is likely to provide further information about the complex interactions between signaling and metabolic pathways. It also highlights the potential of MRS-based metabolomics to identify metabolic signatures that can specifically inform on molecular drug action.
Stem cells in clinical practice: applications and warnings
Daniele Lodi, Tommaso Iannitti, Beniamino Palmieri
Journal of Experimental & Clinical Cancer Research , 2011, DOI: 10.1186/1756-9966-30-9
Abstract: We have searched Pubmed/Medline for clinical trials, involving the use of human stem cells, using the key words "stem cells" combined with the key words "transplantation", "pathology", "guidelines", "properties" and "risks". All the relevant clinical trials have been included. The results have been divided into different categories, basing on the way stem cells have been employed in different pathological conditions.The word "stemness" defines a series of properties which distinguish a heterogeneous variety of cell population. However, in the absence of a current consensus on a gold standard protocol to isolate and identify SCs, the definition of "stemness" is in a continuous evolution [1-3].Biologically, stem cells (SCs) are characterized by self-renewability [4], that is the ability not only to divide themselves rapidly and continuously, but also to create new SCs and progenitors more differentiated than the mother cells. The asymmetric mitosis is the process which permits to obtain two intrinsically different daughter cells. A cell polarizes itself, so that cell-fate determinant molecules are specifically localized on one side. After that, the mitotic spindle aligns itself perpendicularly to the cell axis polarity. At the end of the process two different cells are obtained [5-7].SCs show high plasticity, i.e. the complex ability to cross lineage barriers and adopt the expression profile and functional phenotypes of the cells that are typical of other tissues. The plasticity can be explained by transdifferentiation (direct or indirect) and fusion. Transdifferentiation is the acquisition of the identity of a different phenotype through the expression of the gene pattern of other tissue (direct) or through the achievement of a more primitive state and the successive differentiation to another cell type (indirect or de-differentiation). By fusion with a cell of another tissue, a cell can express a gene and acquire a phenotypic element of another parenchyma [3].SCs mo
Fatal cold agglutinin-induced haemolytic anaemia: a case report
Gianluca Lodi, Daniela Resca, Roberto Reverberi
Journal of Medical Case Reports , 2010, DOI: 10.1186/1752-1947-4-252
Abstract: A 48-year-old Caucasian man presented to our hospital with symptoms of extreme asthenia caused by severe anaemia. The transfusion of red blood cells (O Rh-positive), started as prescribed by the emergency guidelines in force without pre-transfusion tests, induced fatal haemolysis because of the presence of high levels of anti-H antibodies in his blood, that reacted with the large amount of H antigen in universal (0) red blood cells.Emergency transfusion of universal red blood cells (0 Rh-positive or negative) is usually accepted by the international guidelines in force in emergency departments. In this report we describe a rare complication caused by the very high concentration in the recipient of cold agglutinins and the activation of the complement system, responsible for red blood cell lysis and consequent fatal cardiovascular shock. We conclude that emergency transfusion of universal red blood cells (0 Rh-positive or negative) may be dangerous and its risk should be assessed against the risk of delaying transfusion until the pre-transfusion tests are completed.Cold agglutinins were first described by Landsteiner in 1903 [1]. Their pathological action against red blood cells (haemolytic anaemia) and blood vessels (Raynaud's syndrome) was described some years later by Clough and Iwai [2,3]. In 1953 Schubothe coined the term: Cold Agglutinin Disease (CAD) [4].CAD is characterized by an auto-antibody [5] which is able to agglutinate red blood cells (RBCs) at temperatures lower than that of the body, and subsequently to activate the complement system responsible for lysis of RBCs.Patients show haemolytic anaemia of varying degrees of severity, as well as episodes of hemoglobinuria and acrocyanosis, which arise or worsen upon exposure to low temperatures.Cold agglutinin antibodies are mainly specific for the I/i and H RBCs membrane systems [6], and their production can be stimulated by Mycoplasma pneumoniae or infection by the Epstein-Barr virus, as well as by lymphop
Occurrence of Anisakis physeteris Baylis, 1923 and Pseudoterranova sp. (Nematoda) in Pygmy Sperm Whale Kogia breviceps (De Blainvillei, 1838) (Physeteridae) in Northeastern Coast of Brazil
Portes Santos Cláudia,Lodi Liliane
Memórias do Instituto Oswaldo Cruz , 1998,
Group size and composition of Tursiops truncatus (Cetacea: Delphinidae) in a coastal insular habitat off southeastern Brazil
Liliane Lodi,Cassiano Monteiro-Neto
Biotemas , 2012,
Abstract: The aim of the present study was to describe the size and composition of groups of common bottlenose dolphins (Tursiops truncatus) in the Cagarras Archipelago (23°01’S, 43°12’W), Rio de Janeiro, Brazil based on six years of observation (2004 and 2006 to 2010). The group size (n = 51) ranged between three and 30 individuals (mean = 13.7 ± 7.1), and the frequency distribution of group size showed modes at six individuals and 19 individuals. The largest average group size occurred in 2004 (mean 21.4 ± 3.3) and the smallest in 2008 (mean 4.4 ± 0.8). The number of individuals/group decreased over the years and this decrease could be correlated with habitat quality. The average number of immature individuals (neonates, calves and juveniles), expressed as a proportion of the total group size, varied between 0.31 (2006) and 0.4 (2010). This proportion did not vary significantly among years. These results suggest that the Cagarras Archipelago should be considered critical habitat for the survival and /or population growth of T. truncatus in southeastern Brazil.
Always Best Packet Switching: the Mobile VoIP Case Study
Vittorio Ghini,Giorgia Lodi,Fabio Panzieri
Journal of Communications , 2009, DOI: 10.4304/jcm.4.9.700-713
Abstract: Currently, a mobile device equipped with multiple heterogeneous wireless Network Interface Cards (NICs), cannot take fully advantage of its capabilities as the conventional mobility management approach allows it to select and use only one of its NICs at a time. In contrast to this approach, we propose the so-called Always Best Packet Switching (ABPS) model that allows applications to use simultaneously all the available NICs, and switch each given IP datagram through the most suitable NIC, depending on the characteristics of the datagram itself. Specifically, we show that the ABPS model enables mobile applications to create policies for load balancing and recovery purposes in order to support effectively mobile multimedia services. In particular, in this paper we describe a cross-layer mechanism, termed Robust Wireless Multi-Path Channel (RWMPC) that adopts the ABPS model in order to meet effectively interactivity and low packet loss Quality of Service (QoS) requirements of Voice over IP (VoIP) applications, running on mobile hosts equipped with multiple WLAN NICs. By Exploiting the RWMPC services, VoIP applications can establish and maintain separate wireless links with different access points providing access to, possibly independently managed, wireless networks, and select for each UDP datagram the best link to be used for communication purposes. In essence, the RWMPC mechanism monitors each link in use, and notifies the application if detects that a datagram has been lost. In this case, the application retransmits the datagram using an alternative link, available through one of the interfaces homed in the mobile host. We have carried out an experimental evaluation of our mechanism in a real wireless scenario through the emulation of a VoIP application. The results we have obtained from this evaluation are discussed in this paper and confirm the effectiveness of our approach.
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