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Search Results: 1 - 10 of 300681 matches for " Lisa J. Kohler "
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Erdheim-Chester Disease Associated with Marginal Zone Lymphoma and Monoclonal Proteinemia
Peter G. Pavlidakey,Alok Mohanty,Lisa J. Kohler,Howard J. Meyerson
Case Reports in Hematology , 2011, DOI: 10.1155/2011/941637
Abstract: Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis. We report a fatal case of ECD with extensive cardiac involvement associated with a marginal zone lymphoma and monoclonal proteinemia in a young man. This is the first reported association of ECD with a monoclonal gammopathy or a lymphoma.
Seasonal Distribution and Historic Trends in Abundance of White Sharks, Carcharodon carcharias, in the Western North Atlantic Ocean
Tobey H. Curtis, Camilla T. McCandless, John K. Carlson, Gregory B. Skomal, Nancy E. Kohler, Lisa J. Natanson, George H. Burgess, John J. Hoey, Harold L. Pratt
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0099240
Abstract: Despite recent advances in field research on white sharks (Carcharodon carcharias) in several regions around the world, opportunistic capture and sighting records remain the primary source of information on this species in the northwest Atlantic Ocean (NWA). Previous studies using limited datasets have suggested a precipitous decline in the abundance of white sharks from this region, but considerable uncertainty in these studies warrants additional investigation. This study builds upon previously published data combined with recent unpublished records and presents a synthesis of 649 confirmed white shark records from the NWA compiled over a 210-year period (1800-2010), resulting in the largest white shark dataset yet compiled from this region. These comprehensive records were used to update our understanding of their seasonal distribution, relative abundance trends, habitat use, and fisheries interactions. All life stages were present in continental shelf waters year-round, but median latitude of white shark occurrence varied seasonally. White sharks primarily occurred between Massachusetts and New Jersey during summer and off Florida during winter, with broad distribution along the coast during spring and fall. The majority of fishing gear interactions occurred with rod and reel, longline, and gillnet gears. Historic abundance trends from multiple sources support a significant decline in white shark abundance in the 1970s and 1980s, but there have been apparent increases in abundance since the 1990s when a variety of conservation measures were implemented. Though the white shark's inherent vulnerability to exploitation warrants continued protections, our results suggest a more optimistic outlook for the recovery of this iconic predator in the Atlantic.
Shot noise in non-adiabatically driven nanoscale conductors
Franz J. Kaiser,Sigmund Kohler
Physics , 2007, DOI: 10.1002/andp.200710257
Abstract: We investigate the noise properties of pump currents through molecular wires and coupled quantum dots. As a model we employ a two level system that is connected to electron reservoirs and is non-adiabatically driven. Concerning the electron-electron interaction, we focus on two limits: non-interacting electrons and strong Coulomb repulsion. While the former case is treated within a Floquet scattering formalism, we derive for the latter case a master equation formalism for the computation of the current and the zero-frequency noise. For a pump operated close to internal resonances, the differences between the non-interacting and the strongly interacting limit turn out to be surprisingly small.
Fidelity freeze for a random matrix model with off--diagonal perturbation
H. -J. Stoeckmann. H. Kohler
Physics , 2006,
Abstract: The concept of fidelity has been introduced to characterize the stability of a quantum-mechanical system against perturbations. The fidelity amplitude is defined as the overlap integral of a wave packet with itself after the development forth and back under the influence of two slightly different Hamiltonians. It was shown by Prosen and Znidaric in the linear-response approximation that the decay of the fidelity is frozen if the Hamiltonian of the perturbation contains off-diagonal elements only. In the present work the results of Prosen and Znidaric are extended by a supersymmetry calculation to arbitrary strengths of the perturbation for the case of an unperturbed Hamiltonian taken from the Gaussian orthogonal ensemble and a purely unitary antisymmetric perturbation. It is found that for the exact calculation the freeze of fidelity is only slightly reduced as compared to the linear-response approximation. This may have important consequences for the design of quantum computers.
Phase readout of a charge qubit capacitively coupled to an open double quantum dot
C. Kreisbeck,F. J. Kaiser,S. Kohler
Physics , 2009, DOI: 10.1103/PhysRevB.81.125404
Abstract: We study the dynamics of a charge qubit that is capacitively coupled to an open double quantum dot. Depending on the qubit state, the transport through the open quantum dot may be resonant or off-resonant, such that the qubit affects the current through the open double dot. We relate the initial qubit state to the magnitude of an emerging transient current peak. The relation between these quantities enables the readout of not only the charge but also the phase of the qubit.
Neurocognitive performance and behavior before and after treatment for sleep-disordered breathing in children
Mark J Kohler, Kurt Lushington, J Declan Kennedy
Nature and Science of Sleep , 2010, DOI: http://dx.doi.org/10.2147/NSS.S6934
Abstract: rocognitive performance and behavior before and after treatment for sleep-disordered breathing in children Review (3656) Total Article Views Authors: Mark J Kohler, Kurt Lushington, J Declan Kennedy Published Date August 2010 Volume 2010:2 Pages 159 - 185 DOI: http://dx.doi.org/10.2147/NSS.S6934 Mark J Kohler1, Kurt Lushington2, J Declan Kennedy1 1Children’s Research Centre, University of Adelaide, North Adelaide, Australia; 2School of Psychology, Social Work and Social Policy, University of South Australia, Adelaide, Australia Abstract: Neurocognitive and behavioral problems are increasingly reported in children with sleep-disordered breathing (SDB). The impact of treatment for SDB on neurocognition and behavior is, therefore, an issue of increasing importance. To date, there has been little consideration given to the quality of studies when reviewing associated neurocognitive and behavioral problems in children with SDB, and furthermore, there has been little systematic review of treatment outcomes. The aim of this review was to provide an up-to-date and critical review of the current literature. Findings indicate a specific pattern of neurocognitive problems in children with SDB; however, the pattern of behavioral problems is less clear. Very few studies were found to provide a rigorous investigation of posttreatment neurocognitive and behavior outcomes. Despite this, relatively consistent improvements in global intelligence, attention, and visual spatial ability are shown; however, persistent deficits in other domains are also evident. For behavior, problems of hyperactivity, aggression or conduct problems, and somatic complaints improve following treatment. In contrast, symptoms of anxiety and social problems less consistently improve. These findings should aid in the development of more targeted investigations and well-designed studies exploring both the causative mechanisms and the treatment response for neurocognitive and behavior problems in children with SDB.
Comparison of airborne radar altimeter and ground-based Ku-band radar measurements on the ice cap Austfonna, Svalbard
O. Brandt,R. L. Hawley,J. Kohler,J. O. Hagen
The Cryosphere Discussions , 2008,
Abstract: We compare coincident data from the European Space Agency's Airborne SAR/Interferometric Radar Altimeter System (ASIRAS) with ground-based Very High Bandwidth (VHB) stepped-frequency radar measurements in the Ku-band. The ASIRAS instrument obtained data from ~700 m above the surface, using a 13.5 GHz center frequency and a 1 GHz bandwidth. The ground-based VHB radar measurements were acquired using the same center frequency, but with a variable bandwidth of either 1 or 8 GHz. Four sites were visited with the VHB radar; two sites within the transition region from superimposed ice to firn, and two sites in the long-term firn area (wet-snow zone). The greater bandwidth VHB measurements show that the first peak in the airborne data is a composite of the return from the surface (i.e. air-snow interface) and returns of similar or stronger amplitude from reflectors in the upper ~30 cm of the subsurface. The peak position in the airborne data is thus not necessarily a good proxy for the surface since the maximum and width of the first return depend on the degree of interference between surface and subsurface reflectors. The major response from the winter snowpack was found to be caused by units of thin crust/ice layers (0.5–2 mm) surrounded by large crystals (>3 mm). In the airborne data, it is possible to track such layers for tens of kilometers. The winter snowpack lacked thicker ice layers. The last year's summer surface, characterized by a low density large crystal layer overlaying a harder denser layer, gives a strong radar response, frequently the strongest. The clear relationship observed between the VHB and ASIRAS waveforms, justifies the use of ground-based radar measurements in the validation of air- or spaceborne radars.
Form and Function in Grammar Teaching
J. E. Lisa Meyer
TEFLIN Journal , 1998,
Abstract: :In this paper we promote the integration of form-focused grammar teaching with a communicative approach to language learn -ing. After discussion of several principles of L2 acquisition and their pedagogic implications, we recommend a four-stage lesson plan which helps the teacher to focus on a communicative function while presenting a specific grammatical structure. In the proposed lesson structure, teachers are encouraged to guide student. Exploration, dis -covery, and application of grammatical information during specific lesson stages. This type of lesson should pave the way for students to do more than master practice worksheets. One of the greatest ben -efits of this type of lesson is that it gives teachers the confidence to integrate a grammatical focus into their language lessons without violating the essence of communicative approach.
Collaborative Event Ethnography: Conservation and development trade-offs at the fourth world conservation congress
Brosius J,Campbell Lisa
Conservation & Society , 2010,
Aorta Measurements are Heritable and Influenced by Bicuspid Aortic Valve
Lisa J. Martin
Frontiers in Genetics , 2011, DOI: 10.3389/fgene.2011.00061
Abstract: Objectives: To determine whether the contributions of genetics and bicuspid aortic valve (BAV) independently influence aortic (Ao) dimensions. Background: Ao dilation is a risk factor for aneurysm, dissection, and sudden cardiac death. Frequent association of BAV with Ao dilation implicates a common underlying defect possibly due to genetic factors. Methods: Families enriched for BAV underwent standardized transthoracic echocardiography. In addition to BAV status, echocardiographic measures of Ao (annulus to descending Ao), pulmonary artery, and mitral valve annulus (MVA) diameters were obtained. Using variance components analysis, heritability was estimated with and without BAV status. Additionally, bivariate genetic analyses between Ao dimensions and BAV were performed. Results: Our cohort was obtained from 209 families enriched for BAV. After adjusting for age, body surface area, and sex, individuals with BAV had a statistically significant increase in all echocardiographic measurements (p < 0.006) except descending Ao and MVA. Individuals with BAV were at greater odds of having Ao dilation (OR = 4.44, 95% CI 2.93–6.72) than family members without BAV. All echocardiographic measurements exhibited moderate to strong heritability (0.25–0.53), and these estimates were not influenced by inclusion of BAV as a covariate. Bivariate genetic analyses supported that the genetic correlation between BAV and echo measures were not significantly different from zero. Conclusion: We show for the first time that echocardiographic measurements of Ao, pulmonary artery and MVA diameters are quantitative traits that exhibit significant heritability. In addition, our results suggest the presence of BAV independently influences the proximal Ao and pulmonary artery measures but not those in the descending Ao or MVA.
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