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Search Results: 1 - 10 of 10640 matches for " Linyong Du "
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Molecular Cloning, Characterization and Expression Analysis of Macrohage-Colony Stimulating Factor 2 Gene from Grass Carp (Ctenopharyngodon idellus)  [PDF]
Linyong Du, Lei Qin, Shangnian Wang, Lu Yang, Kun Yang, Xinyan Wang, Hong Zhou
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.510B046
Abstract:

Macrophage colony-stimulating factor (CSF-1/M-CSF) is a key factor for the differentiation, growth and survival of monocytes/macrophages and osteoclasts. The functions of M-CSF have been well characterized in mammals. In this study, we have cloned and sequenced the cDNA of M-CSF2 in grass carp. The grass carp M-CSF2 cDNA was 1487 bp in length, containing an open reading frame of 855 bp that encodes 284 amino acids. The deduced protein of grass carp M-CSF2 possessed same domains similar to its mammalian counterparts. Multiple alignments and phylogenetic tree indicate that the grass carp M-CSF2 exhibits close evolutionary relationship with its counterparts in other teleosts. Lastly, the tissue distribution results also showed that the grass carp M-CSF2 transcript was dominantly expressed in head kidney, kidney and spleen in vivo.

Genome-Wide Identification and Analysis of Grape Aldehyde Dehydrogenase (ALDH) Gene Superfamily
Yucheng Zhang, Linyong Mao, Hua Wang, Chad Brocker, Xiangjing Yin, Vasilis Vasiliou, Zhangjun Fei, Xiping Wang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0032153
Abstract: Background The completion of the grape genome sequencing project has paved the way for novel gene discovery and functional analysis. Aldehyde dehydrogenases (ALDHs) comprise a gene superfamily encoding NAD(P)+-dependent enzymes that catalyze the irreversible oxidation of a wide range of endogenous and exogenous aromatic and aliphatic aldehydes. Although ALDHs have been systematically investigated in several plant species including Arabidopsis and rice, our knowledge concerning the ALDH genes, their evolutionary relationship and expression patterns in grape has been limited. Methodology/Principal Findings A total of 23 ALDH genes were identified in the grape genome and grouped into ten families according to the unified nomenclature system developed by the ALDH Gene Nomenclature Committee (AGNC). Members within the same grape ALDH families possess nearly identical exon-intron structures. Evolutionary analysis indicates that both segmental and tandem duplication events have contributed significantly to the expansion of grape ALDH genes. Phylogenetic analysis of ALDH protein sequences from seven plant species indicates that grape ALDHs are more closely related to those of Arabidopsis. In addition, synteny analysis between grape and Arabidopsis shows that homologs of a number of grape ALDHs are found in the corresponding syntenic blocks of Arabidopsis, suggesting that these genes arose before the speciation of the grape and Arabidopsis. Microarray gene expression analysis revealed large number of grape ALDH genes responsive to drought or salt stress. Furthermore, we found a number of ALDH genes showed significantly changed expressions in responses to infection with different pathogens and during grape berry development, suggesting novel roles of ALDH genes in plant-pathogen interactions and berry development. Conclusion The genome-wide identification, evolutionary and expression analysis of grape ALDH genes should facilitate research in this gene family and provide new insights regarding their evolution history and functional roles in plant stress tolerance.
Arabidopsis gene co-expression network and its functional modules
Linyong Mao, John L Van Hemert, Sudhansu Dash, Julie A Dickerson
BMC Bioinformatics , 2009, DOI: 10.1186/1471-2105-10-346
Abstract: We constructed a genome-wide Arabidopsis gene co-expression network (AGCN) by using 1094 microarrays. We then analyzed the topological properties of AGCN and partitioned the network into modules by using an efficient graph clustering algorithm. In the AGCN, 382 hub genes formed a clique, and they were densely connected only to a small subset of the network. At the module level, the network clustering results provide a systems-level understanding of the gene modules that coordinate multiple biological processes to carry out specific biological functions. For instance, the photosynthesis module in AGCN involves a very large number (> 1000) of genes which participate in various biological processes including photosynthesis, electron transport, pigment metabolism, chloroplast organization and biogenesis, cofactor metabolism, protein biosynthesis, and vitamin metabolism. The cell cycle module orchestrated the coordinated expression of hundreds of genes involved in cell cycle, DNA metabolism, and cytoskeleton organization and biogenesis. We also compared the AGCN constructed in this study with a graphical Gaussian model (GGM) based Arabidopsis gene network. The photosynthesis, protein biosynthesis, and cell cycle modules identified from the GGM network had much smaller module sizes compared with the modules found in the AGCN, respectively.This study reveals new insight into the topological properties of biological networks. The preferential hub-hub connections might be necessary for the formation of modular structure in gene co-expression networks. The study also reveals new insight into the organization of gene functional modules.Biological networks characterize the interactions of biomolecules at a systems-level and can help us better understand how biomolecules interact with each other to carry out biological functions in living cells. In the representation of biological networks, it is natural to use graph to describe the interactions between biomolecules. A node in a
Cold-State Investigation on a Flame Holder  [PDF]
Yiqing Du
Journal of Power and Energy Engineering (JPEE) , 2013, DOI: 10.4236/jpee.2013.17008
Abstract:

Slitty bluff body is widely used as a high-performance flame holder in power industry. To understand the flame stability mechanism, the evolution of the near wake over a slitty bluff body in cold state was numerically investigated using the renormalization group (RNG) k-ε model at Reynolds number of 470,000. The coherent structure of the near wake was identified by the vortex shedding simulation. To explain the vortex shedding, a mechanism that single vortex of large size suddenly immerses two shear layers was proposed. To quantitatively compare the near wakes at different gap ratio, a vortex shedding character dimension was first proposed. This character dimension has positive correlation with flame stability. Particle-image velocimetry (PIV) measurements in a close wind tunnel were also carried out to confirm the observation from the numerical study. The evidence shows that the numerical results are of good agreement with the cold-state experiments.

Classification of Single Traveling Wave Solutions to the Generalized Strong Nonlinear Boussinesq Equation without Dissipation Terms in P = 1  [PDF]
Xinghua Du
Journal of Applied Mathematics and Physics (JAMP) , 2014, DOI: 10.4236/jamp.2014.23006
Abstract:

By the complete discrimination system for polynomial method, we obtained the classification of single traveling wave solutions to the generalized strong nonlinear Boussinesq equation without dissipation terms in p=1.

New Fixed Point Theorems of Mixed Monotone Operators  [PDF]
Xinsheng Du
Applied Mathematics (AM) , 2014, DOI: 10.4236/am.2014.53037
Abstract:

Mixed monotone operator is an important nonlinear operator. It exists extensively in the research of nonlinear differential and integral equations. Generally, the research of mixed monotone operators in partially ordered Banach spaces requires compactness, continuity or concavity-convexity of the operators. In this paper, without any compact and continuous assumption, we obtain some new existence and uniqueness theorems of positive fixed point of e-concave-convex mixed monotone operators in Banach spaces partially ordered by a cone, which extends the existing corresponding results.

Existence of Positive Solutions to Semipositone Fractional Differential Equations  [PDF]
Xinsheng Du
Applied Mathematics (AM) , 2016, DOI: 10.4236/am.2016.714127
Abstract: In this paper, by means of constructing a special cone, we obtain a sufficient condition for the existence of positive solution to semipositone fractional differential equation.
A Literature Review on Institutional Environment and Technological Innovation  [PDF]
Zhuoyan Du
American Journal of Industrial and Business Management (AJIBM) , 2018, DOI: 10.4236/ajibm.2018.89130
Abstract: This article is a literature review on institutional environment and technology innovation. The author discusses the origin and classification of the institutional environment, has a through understanding of the institutional environment, and examines studies about institutional environment and technology innovation from different perspectives to reach some constructive suggestions to better promote technology innovation.
The Evolutionary Road: The Common Goal of Human as a Species  [PDF]
Dongdong Du
Open Journal of Philosophy (OJPP) , 2018, DOI: 10.4236/ojpp.2018.85033
Abstract: This paper puts forward the idea of the right, evolution road of all mankind, and emphasizes that it should be regarded as the common purpose of human beings from the view of human evolution. Also from the point of philosophical, it is clarifying the concept of human path, emphasizing the individual and its existence, openness and humanity based on human nature (human emotion, love, care); the rational (thinking, reason) based on reason, experience, learning and research; and two goals: utilitarian and efficiency, the evolutionary of human beings. In the end, from the view of the question they focused on, attribution, solution and attitude towards human nature, it distinguishes the concept between “the evolutionary road of human beings” and “Noble Eightfold Path” to alert people that development, progress, evolutionary path of human is unparalleled and it is the right way for mankind. Purpose: The combination of reason and human nature, so as to enhancing human efficiency, meeting human needs, and ultimately promoting people into the correct, evolutionary path. Method: Descriptive thinking can be used.
Active ingredients and efficacies of Ganoderma lucidum cultivated on non-medicinal parts of Chinese medicinal herbs
中药非药用部位栽培灵芝的活性成分及药效变化

Yaohui Guo,Xia Luo,Mengyao Yu,Linyong Zheng,
郭耀辉
,罗霞,余梦瑶,郑林用

微生物学报 , 2011,
Abstract: Objective] Ganoderma lucidum was cultivated on non-medicinal parts of Salvia miltiorrhiza,Chrysanthemum morifolium,Ptatycodgn grandlfiorum,as all are Chinese traditional herbal medicines.We studied the changes of active ingredients and efficacies of the Ganoderma lucidum fruit bodies.Methods] The agronomic characters,polysaccharide and terpene contents,acute toxicity and efficacy of Ganoderma lucidum grown on the non-medicinal part of the three materials were compared with that grown on the ordinary formu...
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