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Search Results: 1 - 10 of 104200 matches for " Lingyi Zhang "
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A Comparative Study to Understanding about Poetics Based on Natural Language Processing  [PDF]
Lingyi Zhang, Junhui Gao
Open Journal of Modern Linguistics (OJML) , 2017, DOI: 10.4236/ojml.2017.75017
Abstract: This paper tries to find out five poets’ (Thomas Hardy, Wilde, Browning, Yeats, and Tagore) differences and similarities through analyzing their works on nineteenth Century by using natural language understanding technology and word vector model. Firstly, we collect enough poems from these five poets, build five corpus respectively, and calculate their high-frequency words, by using Natural Language Processing method. Then, based on the word vector model, we calculate the word vectors of the five poets’ high-frequency words, and combine the word vectors of each poet into one vector. Finally, we analyze the similarity between the combined word vectors by using the hierarchical clustering method. The result shows that the poems of Hardy, Browning, and Wilde are similar; the poems of Tagore and Yeats are relatively close—but the gap between the two is relatively large. In addition, we evaluate the stability of our approach by altering the word vector dimension, and try to analyze the results of clustering in a literary (poetic) perspective. Yeats and Tagore possessed a kind of mysticism poetics thought, while Hardy, Browning, and Wilde have the elements of realism combined with tragedy and comedy. The results are similar comparing to those we get from the word vector model.
Research on the Interaction between Producer Services and Manufacturing Industry in Shaanxi Province  [PDF]
Lingyi Kong, Xiao Liang
American Journal of Industrial and Business Management (AJIBM) , 2018, DOI: 10.4236/ajibm.2018.85087
Abstract: With the deepening of social division of labor, producer services are gradually separated from manufacturing industry and play a more and more important role in the national economy. In particular, with the rapid development of scientific research, business, law, finance and other industries, the industrial association between the productive service industry and the manufacturing industry becomes more closely. The interactive state between the producer services and manufacturing industry has a direct impact on the industrial upgrading and structural adjustment of all sectors of the national economy, which has become an important way for the economic development of our country in the future. Taking Shaanxi Province as an example, this paper first analyzes the development of producer services and manufacturing in Shaanxi. On this basis, the VAR model is built to analyze the added value of two industries in Shaanxi Province. Finally, according to the empirical results, we put forward relevant countermeasures and suggestions.
BAP31 is frequently overexpressed in patients with primary colorectal cancer and correlates with better prognosis
LingYi Dong,KeWei Jiang,YanBin Zhang,Hui Zhang,HongQing Zhuo,ZhiRong Cui,YingJiang Ye,Shan Wang
Chinese Science Bulletin , 2011, DOI: 10.1007/s11434-011-4610-0
Abstract: We previously showed that B cell receptor associated protein 31(BAP31) was significantly upregulated in colorectal cancer compared with normal mucosa epithelia. However, its expression pattern and pathological role in colorectal cancer are not clearly understood. In this study, we investigated whether the expression of BAP31 was associated with the clinicopathological parameters of colorectal cancer. The expression pattern of BAP31 was detected by immunohistochemistry on a tissue microarray in both primary tumor and paired distant normal mucosa samples from 120 consecutive colorectal cancer patients. Furthermore, BAP31 protein expression was also determined in twenty colorectal adenomas and eight liver metastasis samples. There was positive expression of BAP31 in 64.17% of primary tumors and 6.67% in distant normal mucosa (P=0.000). Negative expression of BAP31 was correlated with distant metastasis (P=0.036) and lower tumor differentiation grade (P=0.001). Patients with BAP31-negative expression showed significantly lower overall survival rate (P=0.003) compared to patients with BAP31-positive expression. Our results demonstrate that BAP31 may serve as a candidate prognostic marker in colorectal cancer and negative BAP31 expression may lead to more aggressive invasion of colorectal cancer.
Genomic characterization of ribitol teichoic acid synthesis in Staphylococcus aureus: genes, genomic organization and gene duplication
Ziliang Qian, Yanbin Yin, Yong Zhang, Lingyi Lu, Yixue Li, Ying Jiang
BMC Genomics , 2006, DOI: 10.1186/1471-2164-7-74
Abstract: We identified all S. aureus tar and tag gene orthologs in the selected S. aureus strains which would contribute to teichoic acids sythesis.Based on our identification of genes orthologous to tarI, tarJ, tarL, which are specific to tar pathway in B. subtilis W23, we also concluded that tar is the major teichoic acid biogenesis pathway in S. aureus. Further analyses indicated that the S. aureus tar genes, different from the divergon organization in B. subtilis, are organized into several clusters in cis. Most interesting, compared with genes in B. subtilis tar pathway, the S. aureus tar specific genes (tarI,J,L) are duplicated in all six S. aureus genomes.In the S. aureus strains we analyzed, tar (teichoic acid ribitol) is the main teichoic acid biogenesis pathway. The tar genes are organized into several genomic groups in cis and the genes specific to tar (relative to tag): tarI, tarJ, tarL are duplicated. The genomic organization of the S. aureus tar pathway suggests their regulations are different when compared to B. subtilis tar or tag pathway, which are grouped in two operons in a divergon structure.Staphylococcus. Aureus (S. aureus) is a Gram-positive bacterium, which causes a variety of suppurative infections and toxinoses in humans. The death rate associated with S. aureus infection is still high even with antimicrobial drug treatments due to the development of antibiotic resistance in Methicillin Resistant Staphylococcus Aureus (MRSA) strains. Current developments in antimicrobial therapeutics show little efficacy in treating S. aureus and this bacterium remains a major human health threat. S. aureus, and in particular its cell wall, remain a major target of glycopeptide antibiotics and focus of bacteriology research.Teichoic acids, polymers of alternating phosphate and alditol groups, in addition to peptidoglycan are an essential component of bacterial cell walls. Teichoic acid biosynthesis in S. aureus has not been well characterized. B. subtilis and S. aur
Method of Leakage Power Simulation and Calculation Based on Full Custom IP Design

Zhang Feng,Zhou Yumei,Huang Lingyi,

半导体学报 , 2004,
Abstract: 提出了一种自顶向下的基于晶体管级的全定制IP漏电流功耗计算方法,该方法计算快速高效,实用性强,取代了以往完全依靠软件仿真进行功耗计算的技术.在设计龙芯 号CPU中的全定制IP时应用了此方法,该芯片采用的是中芯国际0 .18μm CMOS工艺技术.为了验证该方法,把计算结果与Synopsys公司的Nanosim仿真结果进行对比,误差只有10 %左右.由于软件仿真需要大量的测试激励与计算时间,而该方法不需要外加测试激励便可以计算出全定制IP漏电流功耗,并能快速找到其模块所在位置,使设计周期大为缩短,因此完全可以针对这种计算方法开发相应软件及进行应用
A New Fast Simulation and Calculation Model Based On SRAM

Zhang Feng,ZHOU Yumei,Huang Lingyi,

半导体学报 , 2005,
Abstract: 根据静态随机存储器(SRAM)电路及版图的设计特点,提出了一种新的可用于SRAM设计的快速仿真计算模型.该模型仿真快速准确,能克服Spice仿真软件对大容量SRAM版图后仿真速度较慢的缺点,在很大程度上缩短了设计周期.同时,它的仿真结果同Synopsys公司的Nanosim软件仿真结果相比偏差小于5%.该模型在龙芯Ⅱ号CPU的SRAM设计中得到了应用;芯片采用的是中芯国际0.18μm CMOS工艺.流片验证了该模型对于大容量的SRAM设计是准确而有效的.
Current progress and prospects of induced pluripotent stem cells
LingYi Chen,Lin Liu
Science China Life Sciences , 2009, DOI: 10.1007/s11427-009-0092-6
Abstract: Induced pluripotent stem (iPS) cells are derived from somatic cells by ectopic expression of few transcription factors. Like embryonic stem (ES) cells, iPS cells are able to self-renew indefinitely and to differentiate into all types of cells in the body. iPS cells hold great promise for regenerative medicine, because iPS cells circumvent not only immunological rejection but also ethical issues. Since the first report on the derivation of iPS cells in 2006, many laboratories all over the world started research on iPS cells and have made significant progress. This paper reviews recent progress in iPS cell research, including the methods to generate iPS cells, the molecular mechanism of reprogramming in the formation of iPS cells, and the potential applications of iPS cells in cell replacement therapy. Current problems that need to be addressed and the prospects for iPS research are also discussed.
Economic Determinants of Happiness
Teng Guo,Lingyi Hu
Statistics , 2011,
Abstract: Many scholars have recently begun to dispute the assumed link between individual wellbeing and economic conditions and the extent to which the latter matters (Easterlin, 1995; Stevenson and Wolfers 2008; Tella and MacCulloch 2008). This dilemma is empirically demonstrated in the Latin America Public Opinion Project (LAPOP, 2011), which surveyed North and Latin America in terms of perceived life satisfaction. Higher measures found in the less developed countries of Brazil, Costa Rica, and Panama than in North America pose an intriguing quandary to traditional economic theory. In light of this predicament this paper aims to construct a sensible measure of the national happiness level for the United States on a year by year basis; and regress this against indicators of the national economy to provide insight into this puzzling enigma between national happiness and economic forces
Preparation and evaluation of an eremomycin-bonded chiral monolithic column for capillary electrochromatography

LEI Wen,ZHANG Lingyi,WAN Li,ZHU Yaxian,QIN Sasa,ZHANG Weibing,

色谱 , 2010,
Abstract: Based on the high activity of epoxy group of glycidyl methacrylate monolith, eremomycin-bonded chiral stationary phase (CSP) which has 22 different types of chiral centers was prepared by a one-step derivatization process. The preparation conditions were optimized and the preparation can be carried out in a wide pH range (6.0~9.0). The optimized concentration of eremomycin reactant solution was 42 g/L. The optimized method was simple and mild. Prepared CSP was evaluated by separating racemic mixtures of five amino acids and a chiral drug (rosiglitazone) in capillary electrochromatography mode and all of enantiomers were baseline separated. Analysis time of each pair of enantiomers was less than 4 min, so that rapid analysis can be achieved. The effects of organic modifier, buffer pH, and buffer concentration on the separation were investigated. It shows that eremomycin-bonded CSP has good chiral recognition ability. Chiral recognition mechanisms of different solutes on eremomycin-bonded CSP are discussed.
Improvement of interface in comprehensive two-dimensional liquid chromatography and its application in the research of proteomics

LI Duxin,ZHANG Lingyi,LI Tong,DU Yiping,ZHANG Weibing,

色谱 , 2010,
Abstract: A two-dimensional liquid chromatography (2D-LC) system was constructed with improved trap column interface. Weak anion exchange (WAX) LC was used as the first dimension separation mode and reversed-phase (RP) LC as the second dimension. Two 35 mm long columns (column 1 and column 2) were used as trap columns to retain the fraction from the first dimension, and forward-flushing was employed to pre-separate the components when the trap column was connected to the second dimension. The interface greatly increases the efficiency of the second dimension column without losing the separation speed. Rat serum sample was separated on this system to evaluate the performance of the constructed system. The viscous fingering (VF) phenomenon was generated attribute to the difference in the velocities of the mobile phases of the two dimensions. The separation efficiency was theoretically increased by 70% when the 35 mm trap columns were used in the forward-flush mode.
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