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Search Results: 1 - 10 of 44920 matches for " Ling Huang "
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Hydrophilic Silica/Copolymer Nanoparticles and Protein-Resistance Coatings  [PDF]
Hongpu Huang, Ling He
Journal of Materials Science and Chemical Engineering (MSCE) , 2016, DOI: 10.4236/msce.2016.41004

Hydrophilic silica/copolymer nanoparticles of SiO2-g-P(PEGMA)-b-P(PEG) are prepared by silica surface-initiating atom transfer radical polymerization (SI-ATRP) of poly (ethylene glycol) methyl ether methacrylate (PEGMA) and poly(ethylene glycol) methacrylate (PEG), by using Three molar ratios of SiO2-Br/PEGMA/PEG as 1/42.46/19.44, 1/42.46/38.88 and 1/42.46/77.76. Their temperature sensitive behaviour, pH response and surface properties as protein-resistance coatings are characterized. 220 nm core-shell nanoparticles as P(PEGMA)-b-P(PEG) shell grafted on SiO2 core are formed in water solution, which gained LCST at 60C - 77C and good dispersion in water when pH > 5.0. The water-casted films by SiO2-g-P(PEGMA)-b-P(PEG) obtain a little rough surface (Ra = 26.8 - 29.7 nm). While, the introduction of P(PEG) segments could slight increase the protein-repelling adsorption of SiO2-g-P(PEGMA)-b-P(PEG) films (f = ?6.96 Hz ~ ?7.25 Hz) compared with SiO2-g-P(PEGMA) films (f = ?9.5 Hz). Therefore, SiO2-g-P(PEGMA)-b-P(PEG) could be used as protein-resistance coatings.

Emotional Speech Synthesis Based on Prosodic Feature Modification  [PDF]
Ling He, Hua Huang, Margaret Lech
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.510B015

The synthesis of emotional speech has wide applications in the field of human-computer interaction, medicine, industry and so on. In this work, an emotional speech synthesis system is proposed based on prosodic features modification and Time Domain Pitch Synchronous OverLap Add (TD-PSOLA) waveform concatenative algorithm. The system produces synthesized speech with four types of emotion: angry, happy, sad and bored. The experiment results show that the proposed emotional speech synthesis system achieves a good performance. The produced utterances present clear emotional expression. The subjective test reaches high classification accuracy for different types of synthesized emotional speech utterances.

A Pseudospectral Approach for Kirchhoff Plate Bending Problems with Uncertainties
Ling Guo,Jianguo Huang
Mathematical Problems in Engineering , 2012, DOI: 10.1155/2012/750605
Abstract: This paper proposes a pseudospectral approach for the Kirchhoff plate bending problem with uncertainties. The Karhunen-Loève expansion is used to transform the original problem to a stochastic fourth-order PDE depending only on a finite number of random variables. For the latter problem, its exact solution is approximated by a gPC expansion, with the coefficients obtained by the sparse grid method. The main novelty of the method is that it can be carried out in parallel directly while keeping the high accuracy and fast convergence of the gPC expansion. Several numerical results are performed to show the accuracy and performance of the method.
Stimulation and conformational change of Goα induced by GAP-43
Ling Zhang,Youguo Huang
Science China Life Sciences , 2003, DOI: 10.1360/03yc9019
Abstract: GAP-43 and Go are peripheral membrane proteins enriched in neuronal growth cone. GAP-43 was highly purified from bovine cerebral cortex and myristoylated Goα was highly purified from Escherichia coli cotransformed with pQE60 Goα and pBB131 (NMT). GAP-43 stimulated GTPγS binding to Goα and the stimulation effect was dependent on concentration of GAP-43. Protein-protein binding experiments using CaM-Sepharose affinity media revealed that Goα GDP bound GAP-43 directly to form intermolecular complex. This interaction induced conformational change of Goα. In the presence of GAP-43, fluorescence spectrum of Goα GDP blue shifted 4 nm; fluorescence intensity increased 35.3% and apparent quenching constant (Ksv) increased from (1.1 ±0.22) ×105 to (4.1±0.43) × 105 (M 1). However, no obvious changes of fluorescence spectra of Goα GTPγS were observed in the absence or presence of GAP-43. Our results indicated that GAP-43 induced conformational change of Goα GDP so as to accelerate GDP release and subsequent GTPγS binding, which activates G proteins to trigger signal transduction and amplification. These results provided insights into understanding the function of G proteins in coupling between receptors and effectors and the key role of GDP/GTP exchange mode in GTPase cycle.
(2,2′-Bipyridine-κ2N,N′)hydroxido[N-(4-tolylsulfonyl)alaninato-κ2N,O1]copper(II) hemihydrate
Miao-Ling Huang
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810037529
Abstract: In the title complex, [Cu(C10H12NO4S)(OH)(C10H8N2)]·0.5H2O, the Cu(II) ion shows a distorted square-pyramidal coordination geometry with two N atoms from the 2,2′-bipyridine ligand and one N and one O atom from the N-tosyl-α-alaninato ligand forming the basis of the coordination polyhedron and another O atom of the hydroxo group acting as the apex of the pyramid. The solvent water molecule is statistically disordered over two positions.
Miao-Ling Huang
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810036135
Abstract: In the title complex, [Cu(C9H9NO4S)(C12H8N2)(H2O)], the CuII ion is coordinated in a distorted square-pyramidal geometry by the two N atoms from a 1,10-phenanthroline ligand, one N atom from the deprotonated amino group of an N-tosylglycinate ligand, one O atom from the carboxylate part of the N-tosylglycinate ligand and a water O atom. Intermolecular O—H...O hydrogen bonds involving the water H atoms link neighboring molecules into supramolecular chains along [010]. Weak π–π stacking interactions [centroid–centroid distances of 3.456 (1) and 3.691 (1) ] between the benzene rings of 1,10-phenanthroline ligands of adjacent molecules extend the chains into a layer structure parallel to (001).
Yi Ling Huang
Opticon1826 , 2010, DOI: 10.5334/opt.081001
Yi Ling Huang
Opticon1826 , 2011, DOI: 10.5334/opt.101101
Yi Ling Huang
Opticon1826 , 2010, DOI: 10.5334/opt.091001
4,4′-Bipyridine–4-(p-toluenesulfonamido)benzoic acid (1/2)
Miao-Ling Huang
Acta Crystallographica Section E , 2011, DOI: 10.1107/s1600536811034544
Abstract: In the title compound, C14H13NO4S·0.5C10H8N2, the two benzene rings are nearly perpendicular to each other [dihedral angle = 83.21 (10)°]. The bipyridine molecule is centrosymmetric, the mid-point of the C—C bond linking the pyridine rings being located on an inversion center. Intermolecular N—H...O and O—H...N hydrogen bonds and weak intermolecular C—H...O hydrogen bonds are present in the crystal structure.
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