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Search Results: 1 - 10 of 38189 matches for " Lin HY "
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Cloning, expression and location of RNase9 in human epididymis
J Liu, JY Li, HY Wang, CL Zhang, N Li, YQ Lin, J Liu, WT Wang
BMC Research Notes , 2008, DOI: 10.1186/1756-0500-1-111
Abstract: It was predicted that human RNase9 gene was located on chromosome 14q11.2 and encoded a 205 amino acids protein with a signal peptide of 26 amino acids at the N-terminus. The protein had eight conserved cysteine residues characteristic of the RNase A family members and several potential post-translational modification sites.At the transcriptional level, RNase9 was expressed in a wide variety of tissues, and the expression was higher in men than in boys. RNase9 was localized to the post-equatorial region of the sperms' head. Immunofluorescence staining showed that RNase9 protein was present mostly in the epithelium of the epididymal tubule. Recombinant RNase9 had no ribonuclease activity. In addition, RNase9 had no detectable effect on sperm motility and fertilization as demonstrated by blocking spermatozoa with anti-RNase9 polyclonal serum.RNase9 is expressed in a wide variety of tissues. It is located on the post-equatorial region of the sperm head and the epithelium of epididymal tubule. Although RNase9 belongs to the RNase A family, it has no ribonuclease activity.The epididymis is a long, convoluted duct. As immature spermatozoa move through the epididymis, they are transformed into fully motile and fertile sperm cells through sequential interactions with proteins present in the luminal fluid of the epididymis [1]. At least 200 proteins are present in the epididymal lumen [2]; however, the in vivo function of most of these proteins is unclear. Exploring the function of these epididymal proteins will be necessary for a full understanding of sperm maturation and potentially will lead to the identification of new drug targets for male contraception. RNase9 initially was identified in mouse epididymis through in silico analysis of expressed sequence tags (ESTs) in the UniGene library collection. Later, Devor et. al. identified human RNase9 in the human genome assembly, but the function of this gene is unknown and the characterization has yet to be done.GENSCAN http:
Production of polyploids from cultured shoot tips of Eucalyptus globulus Labill by treatment with colchicine
H Lin, M Jian, LY Liang, WJ Pei, XZ Liu, HY Zhang
African Journal of Biotechnology , 2010,
Abstract: Polyploids from cultured shoot tips of Eucalyptus globulus were produced by treatment with colchicine. Results showed that the combination of 0.5% colchicine and treating multiple shoot clumps for 4 days was the most appropriate conditions for E. globulus polyploidy induction and the effect of the use of multiple shoot clumps for colchicine polyploidy-induced was better than single buds. By comparing the polyploidy plants with normal diploid ones in morphology, leaves of polyploid plants were thicker, larger, and darker green. The chromosome number of polyploidy plants that had been identified in morphology was 2n = 4x = 44, while that of diploids was 2n = 2x = 22.
In vitro suppression of oral squamous cell carcinoma growth by ultrasound-mediated delivery of curcumin microemulsions
Lin HY, Thomas JL, Chen HW, Shen CM, Yang WJ, Lee MH
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S28510
Abstract: vitro suppression of oral squamous cell carcinoma growth by ultrasound-mediated delivery of curcumin microemulsions Original Research (2984) Total Article Views Authors: Lin HY, Thomas JL, Chen HW, Shen CM, Yang WJ, Lee MH Published Date February 2012 Volume 2012:7 Pages 941 - 951 DOI: http://dx.doi.org/10.2147/IJN.S28510 Received: 23 November 2011 Accepted: 12 January 2012 Published: 21 February 2012 Hung-Yin Lin1,2, James L Thomas3, Huan-Wen Chen1, Chih-Min Shen4, Wen-Jen Yang2, Mei-Hwa Lee4 1Department of Chemical and Materials Engineering, National University of Kaohsiung, Kaohsiung, Taiwan; 2Institute of Biotechnology, National University of Kaohsiung, Kaohsiung, Taiwan; 3Department of Physics and Astronomy, University of New Mexico, Albuquerque, NM; 4Department of Materials Science and Engineering, I-Shou University, Kaohsiung, Taiwan Abstract: There is increasing interest in using natural products as anticancer agents, as many have antioxidative properties that may help to prevent cellular damage that can lead to cancer. In addition, there is the expectation that many natural products will have low toxicity and few side effects. However, most anticancer and antioxidative agents are hydrophobic, reducing their bioavailability in vivo and making them problematic to deliver. Curcumin provides a good model system for study. In low doses it shows both anticancer and antioxidation effects, whereas in high doses and delivered locally it could be cytotoxic for cancer cells. In this paper, curcumin microemulsions were formed with food-grade chemicals, including soybean lecithin, soybean oil, and Tween 80, a Food and Drug Administration-approved surfactant. The optimized composition formed curcumin microemulsions with a mean size of 40–50 nm, carrying a concentration of curcumin as high as 15 μM. The stability of curcumin microemulsions refrigerated at 5°C over at least 968 days was assessed by size distribution and zeta potential. The effects of low-frequency ultrasound on two oral squamous cell carcinoma cell lines (OSCC-4 and OSCC-25), and the synergy between treatment with curcumin microemulsions and low-frequency sonic stimulation, were tested. Finally, microscopic imaging of the cells confirmed the toxic effects of the curcumin microemulsions, showing damaged and ruptured cells after treatment. Brief exposure to the curcumin-containing microemulsions did have cytotoxic effects, but the addition of ultrasound strongly enhanced those effects, especially on OSCC-25 cells.
Energy use and gross margin analysis for sesame production in organic and inorganic fertiliser user farms in Nigeria
HS Umar, HY Ibrahim
African Crop Science Journal , 2012,
Abstract: As the negative impacts of energy by-products affect the climate, the knowledge and efficient use of energy in crop production will minimise environmental problems and promote sustainable agriculture as an economic production system in Nigeria and else where. The aim of the study was to evaluate energy use and gross margin estimate between sesame (Sesamum indicum) production using organic and inorganic fertilisers in North-central Nigeria. A sample of 120 sesame farmers comprising of 60 organic and 60 inorganic fertilisers user-farmers was used. A structured questionnaire was used in data collection. The results show that the total energy input expended in the production of sesame using organic and inorganic fertilisers were 2,377 and 2,960 MJ ha-1 respectively. Diesel and labour energy inputs dominated the total energy inputs for the two systems. The energy outputs obtained were 13,900 and 15,000 MJ, respectively. Renewable energy input utilisation was higher (50%) in organic than in inorganic fertilised farms (24%). Energy efficiency and productivity was higher in organic than inorganic sesame farms by 14 and 13%, respectively. The gross margin earned per hectare by organic fertiliser user- farmers was lower by only 5% than that of inorganic fertiliser farmers; but returns on investments were equal at (US$0.02). Hence, since organic farms were more energy efficient and productive, and returns on investment was equal, it is recommended that sesame production using organic fertiliser should be encouraged across Nasarawa State in Nigeria, for environmental and income sustainability.
Advance of molecular marker application in the tobacco research
XZ Liu, HY Zhang
African Journal of Biotechnology , 2008,
Abstract: Tobacco (Nicotiana spp.) is one of the most important commercial crops in the world. During the last two decades, molecular markers have entered the scene of genetic improvement in different fields of agricultural research. The principles and characteristics of several molecular markers such as RFLP, RAPD, AFLP, microsatellites and minisatellites applied in tobacco genetics and breeding were reviewed. The application and development of molecular marker in tobacco genetic research was presented emphatically in the following areas: evolutionary genetics, population genetics and genotyping of cultivars, mapping and tagging of genes, and diversity analysis of germplasm. Finally, the perspective of molecular marker’s application in tobacco genetic breeding in the future was discussed.
Revision of the Eocene decapod crustaceans deposited in the Liptovské múzeum ierny Orol (Liptovsky Mikulá , Slovakia)
Matú? Hy?ny
Acta Geologica Slovaca , 2010,
Abstract: Decapod crustaceans originating from the Eocene strata of the Borové Formation of Liptovská kotlina Depression and deposited in the Liptovské múzeum – ierny Orol in Liptovsky Mikulá , Slovakia were re-examined. Two taxa, Lophoranina reussi (Raninidae) and Harpactoxanthopsis quadrilobata (Zanthopsidae), were identified. In the latter, sexual dimorphism is observable in the nature of abdomina. Additional field works in the studied area may provide more data on the already known decapod association.
Wavelet Transform for Processing Power Quality Disturbances
Chen S,Zhu HY
EURASIP Journal on Advances in Signal Processing , 2007,
Abstract: The emergence of power quality as a topical issue in power systems in the 1990s largely coincides with the huge advancements achieved in the computing technology and information theory. This unsurprisingly has spurred the development of more sophisticated instruments for measuring power quality disturbances and the use of new methods in processing and analyzing the measurements. Fourier theory was the core of many traditional techniques and it is still widely used today. However, it is increasingly being replaced by newer approaches notably wavelet transform and especially in the post-event processing of the time-varying phenomena. This paper reviews the use of wavelet transform approach in processing power quality data. The strengths, limitations, and challenges in employing the methods are discussed with consideration of the needs and expectations when analyzing power quality disturbances. Several examples are given and discussions are made on the various design issues and considerations, which would be useful to those contemplating adopting wavelet transform in power quality applications. A new approach of combining wavelet transform and rank correlation is introduced as an alternative method for identifying capacitor-switching transients.
Numerical solution of the helmholtz equation for the superellipsoid via the galerkin method
Yajni Warnapala,Hy Dinh
Communications in Numerical Analysis , 2013, DOI: 10.5899/2013/cna-00178
Abstract: The objective of this work was to find the numerical solution of the Dirichlet problem for the Helmholtz equation for a smooth superellipsoid. The superellipsoid is a shape that is controlled by two parameters. There are some numerical issues in this type of an analysis; any integration method is affected by the wave number k, because of the oscillatory behavior of the fundamental solution. In this case we could only obtain good numerical results for super ellipsoids that were more shaped like super cones, which is a narrow range of super ellipsoids. The formula for these shapes was: $x=cos(x)sin(y)^{n},y=sin(x)sin(y)^{n},z=cos(y)$ where $n$ varied from 0.5 to 4. The Helmholtz equation, which is the modified wave equation, is used in many scattering problems. This project was funded by NASA RI Space Grant for testing of the Dirichlet boundary condition for the shape of the superellipsoid. One practical value of all these computations can be getting a shape for the engine nacelles in a ray tracing the space shuttle. We are researching the feasibility of obtaining good convergence results for the superellipsoid surface. It was our view that smaller and lighter wave numbers would reduce computational costs associated with obtaining Galerkin coefficients. In addition, we hoped to significantly reduce the number of terms in the infinite series needed to modify the original integral equation, all of which were achieved in the analysis of the superellipsoid in a finite range. We used the Green's theorem to solve the integral equation for the boundary of the surface. Previously, multiple surfaces were used to test this method, such as the sphere, ellipsoid, and perturbation of the sphere, pseudosphere and the oval of Cassini Lin and Warnapala , Warnapala and Morgan .
Weak pre pseudo effect algebras and generalized weak pre pseudo effect algebras
Marek Hy?ko
Mathematics , 2015,
Abstract: Present article concerns the generalization of the results of I. Chajda and J. K\"{u}hr to a non-commutative setting resulting into so called (weak) pre pseudo effect algebras and generalized pre pseudo effect algebras.
Simulations of the Microwave Sky
Neelima Sehgal,Paul Bode,Sudeep Das,Carlos Hernandez-Monteagudo,Kevin Huffenberger,Yen-Ting Lin,Jeremiah P. Ostriker,Hy Trac
Physics , 2009, DOI: 10.1088/0004-637X/709/2/920
Abstract: We create realistic, full-sky, half-arcminute resolution simulations of the microwave sky matched to the most recent astrophysical observations. The primary purpose of these simulations is to test the data reduction pipeline for the Atacama Cosmology Telescope (ACT) experiment; however, we have widened the frequency coverage beyond the ACT bands to make these simulations applicable to other microwave background experiments. Some of the novel features of these simulations are that the radio and infrared galaxy populations are correlated with the galaxy cluster populations, the CMB is lensed by the dark matter structure in the simulation via a ray-tracing code, the contribution to the thermal and kinetic Sunyaev-Zel'dovich (SZ) signals from galaxy clusters, groups, and the IGM has been included, and the gas prescription to model the SZ signals matches the most recent X-ray observations. Regarding the contamination of cluster SZ flux by radio galaxies, we find for 148 GHz (90 GHz) only 3% (4%) of halos have their SZ decrements contaminated at a level of 20% or more. We find the contamination levels higher for infrared galaxies. However, at 90 GHz, less than 20% of clusters with M_{200} > 2.5 x 10^{14} Msun and z<1.2 have their SZ decrements filled in at a level of 20% or more. At 148 GHz, less than 20% of clusters with M_{200} > 2.5 x 10^{14} Msun and z<0.8 have their SZ decrements filled in at a level of 50% or larger. Our models also suggest that a population of very high flux infrared galaxies, which are likely lensed sources, contribute most to the SZ contamination of very massive clusters at 90 and 148 GHz. These simulations are publicly available and should serve as a useful tool for microwave surveys to cross-check SZ cluster detection, power spectrum, and cross-correlation analyses.
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