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Search Results: 1 - 10 of 134319 matches for " Li Guang "
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Vitamin E Therapy in Non-Alcoholic Fatty Liver Disease  [PDF]
Xiangbing Shu, Li Zhang, Guang Ji
International Journal of Clinical Medicine (IJCM) , 2014, DOI: 10.4236/ijcm.2014.53016

Non-alcoholic fatty liver disease (NAFLD) is closely related to oxidative stress. Vitamin E (VE) is an effective antioxidant, which could relieve NAFLD symptoms by improving the balance of oxidation and anti-oxidation. However, recent researches indicate that the functional mechanisms of VE are not only limited to anti-oxidation, but also include adjusting the metabolism disorders of glucose and lipid. Furthermore, the efficacy of VE remains controversial in the treatment of NAFLD by far, and the suitable condition of patient, drug dosage, drug safety and course of treatment during clinical application still need to be discussed. Therefore, this paper reviewed the recent study progresses of clinical application of VE alone and VE and other drugs.

Effects of Flow Rate and Viscosity on Slip Factor of Centrifugal Pump Handling Viscous Oils
Wen-Guang Li
International Journal of Rotating Machinery , 2013, DOI: 10.1155/2013/317473
Abstract: Slip factor is an important parameter in the hydraulic design of centrifugal pump impeller for handling viscous oils. How to extract the factor from CFD computational results and how flow rate and liquid viscosity to affect it remain unclear. In the present paper, the flip factor was estimated by means of two approaches: one is from the velocity triangles at the impeller outlet and the other is due to the impeller theoretical head of 3D turbulent viscous fluid. The velocity of water and viscous oils in the impeller and volute computed by CFD was validated with LDV measurements at the best efficiency point. The effect of exit blade angle on slip factor was clarified. It was shown that the two approaches result into two different slip factors. The factors are significantly dependent of flow rate; however, the liquid viscosity seems to take less effect on them. Volute is responsible for reduction in tangential velocity of liquid at the outlet of impeller at low flow rates. The slip factor of impeller with large exit blade angle is not sensitive to flow rate. 1. Introduction The performance of centrifugal pump handling water and viscous oils was investigated numerically by using a CFD code FLUENT based on a steady, 3D, and incompressible turbulent flow. The turbulence effect was involved with the standard turbulence model and wall roughness was taken into account with the nonequilibrium wall function in [1]. The effect of liquid viscosity on pump performance was clarified through observing the pump head and hydraulic efficiency as well as hydraulic loss coefficient in terms of flow rate. A comparison of computed and experimental overall performance of the pump was made. It was confirmed that the “sudden-rising head effect” exists and is caused from the high viscosity and certain large surface roughness. The volute results in an increasing influence on the flow around the impeller exit at a low flow rate. Slip factor is one important design parameter for deciding a correct impeller diameter of centrifugal pump. The factor can be obtained theoretically and experimentally. The typical investigations include those conducted by Kasai [2, 3], Sakai and Watanabe [4], Noorbakhsh [5], Whitfield [6], Murata et al. [7], Harada and Senoo [8], Visser et al. [9], von Backstron [10], Hassenpflug [11], Ji et al. [12], Qiu et al. [13], and so on. The slip factor depends on impeller geometry [5, 7, 9, 10, 14], flow rate [2–4, 6, 13, 15], and viscosity of the liquid pumped [16, 17]. Recently, Slip factor is increasingly estimated by using CFD approach [18–22]. Thus it is
Fitting evolutionary process of matrix protein 2 family from influenza A virus using analytical solution of differential equation  [PDF]
Shao-Min Yan, Zhen-Chong Li, Guang Wu
Journal of Biomedical Science and Engineering (JBiSE) , 2009, DOI: 10.4236/jbise.2009.28085
Abstract: The evolution of protein family is a process along the time course, thus any mathematical methods that can describe a process over time could be possible to describe an evolutionary process. In our previously concept-initiated study, we attempted to use the differential equation to describe the evolution of hemagglutinins from influenza A viruses, and to discuss various issues related to the building of differential equation. In this study, we attempted not only to use the differential equation to describe the evolution of matrix protein 2 family from influenza A virus, but also to use the analytical solution to fit its evolutionary process. The results showed that the fitting was possible and workable. The fitted model parameters provided a way to further determine the evolutionary dynamics and kinetics, a way to more precisely predict the time of occurrence of mutation, and a way to figure out the interaction between protein family and its environment.
The prevalence of virulent clonal strains of mutans streptococci in vivo and co-culture succession of the strains in vitro—Virulence potential of mutans streptococci  [PDF]
Mingyu Li, Guang-yun Lai, Jun Wang
Open Journal of Stomatology (OJST) , 2011, DOI: 10.4236/ojst.2011.12004
Abstract: Purpose:To examine selected putative virulent prop-erties of mutans streptococci in two groups with dif-ferent caries activity and to examine co-culture hy-bridization of the strains in vitro. Methods: A set of strains from caries-free subjects (115) and another set from caries-active subjects (165) were isolated. Each strain was characterized for three virulence determi-nants. The clinical bacteria were then cocultured by three strains exhibiting the highest levels of virulence. Isolate colonies of last filial generation bacteria were enrichment-incubated and estimated for virulence again. RAPD-PCR and MLEE analyses were processed for parental bacteria and last filial genera-tion one. Results: No difference associated with caries activity of the subjects from whom the isolates origi-nated. Virulent properties of a filial generation strains was not different in the same generation, but was very different from their parent strains. Conclu-sion: The coexist properties of virulent polyclonal strain of MS may hold in a very general conditional sense in a dental plaque ecosystem in vivo, however, one of the co-culture strains may became dominant and displa- ced the others as the result of continuous ecological succession in vitro.
Study on Complex System Evaluation Method Based on PCA and Grey Relative Degree  [PDF]
Yongchun Li, Baowei Song, Jun Jiang, Guang Pan, Ming Chang
Intelligent Control and Automation (ICA) , 2012, DOI: 10.4236/ica.2012.31002
Abstract: The complexity and limited data samples in evaluation of complex system are obstacles for traditional evaluation method. Based on Grey relative degree theory and principal components analysis (PCA) method, a novel systemic evaluation method is put forward in this paper. Firstly, standardization method is modified for evaluation objective, and the method includes expression (2) and (3). Secondly, for few schemes of complex system, grey relative degree, expression (5), is substituted for relation coefficient. At last, validity of the method is verified by evaluating 3 schemes of a type of UUV.
Design of New-generation Electric Vehicle Terminal  [PDF]
Lei Li, Xin Lu, Jiasheng He, Zhe Sun, Guang Yang
Energy and Power Engineering (EPE) , 2013, DOI: 10.4236/epe.2013.54B258

EVT (electric vehicle terminal) has played an important role in EV (electric vehicle) operation. Based on research status of vehicle terminal, EVT brought about in the future should have the following functions: (1) fundamental functions, including real-time monitoring of batteries, guidance in station, position guidance of charging/battery-swap infrastructures, communication with OMS (operation and management system), and so on; (2) advanced functions, including but not limited to multi-media entertainment, subscribing and payment for charging/battery-swap, identification, and safety control during driving. Complete design of new-generation EVT in software structure and hardware architecture is proposed; a new idea of the application of EVT in EV industry is put forward.

Ballistics firearm identification by digital holography
LI Dong-guang,

重庆邮电大学学报(自然科学版) , 2009,
Abstract: The need for firearm identification systems by police services continues to increase with greater accessibility to weapons in the national and international contexts. The difficulties associated with traditional imaging of ballistics specimens are numerous, and include the smallness of the samples, the nature of the surfaces and shapes for the cartridge cases and projectiles. The digital holography has been introduced to create the 3D image of the fired bullets in order to identify firearms. In digital holography a CCD camera records optically generated holograms which is then reconstructed numerically by a calculation of scalar diffraction in the Fresnel approximation. The digital photography facilitates real time transmission of the message via traditional communication methods. In this paper the principle of digital holography and its application to the 3D image encryption-decryption were reviewed. The experimental results of firearm identification recording using digital holography and their numerical reconstruction were presented.
The origin and evolution of ARGFX homeobox loci in mammalian radiation
Guang Li, Peter WH Holland
BMC Evolutionary Biology , 2010, DOI: 10.1186/1471-2148-10-182
Abstract: Phylogenetic and phylogenomic analyses suggest that ARGFX originated by gene duplication from Otx1, Otx2 or Crx during early mammalian evolution, most likely on the stem lineage of the eutherians. ARGFX diverged extensively from its progenitor homeobox gene and its exons have been functional and subject to purifying selection through much of placental mammal radiation. Surprisingly, the coding region is disrupted in most mammalian genomes analysed, with human being the only mammal identified in which the full open reading frame is retained. Indeed, we describe a transcript from human testis that has the potential to encode the full deduced protein.The unusual pattern of evolution suggests that the ARGFX gene may encode a functional RNA or alternatively it may have 'flickered' between functional and non-functional states in the evolutionary history of mammals, particularly in the period when many mammalian lineages diverged within a relatively short time span.The homeobox genes comprise a large and diverse gene superclass characterized by presence of a DNA motif encoding the homeodomain. Most homeodomain proteins function as transcription factors involved in switching other genes on or off during embryonic development, cell fate specification and cell differentiation. The pivotal importance of homeobox genes to animal development is demonstrated by the fact that mutation or experimental misexpression can cause dramatic developmental abnormalities or cancers [1-3]. The best known homeobox genes include Hox, ParaHox, NK, Otx, Pax and Dlx genes which have been extensively studied in many animal model systems including mice, zebrafish, nematodes and Drosophila. Indeed, it was comparison of homeobox genes between species that led to one of the most striking findings of twentieth century biology: the remarkable conservation of homeobox and other developmental patterning genes between very divergent animal phyla [4,5].Not all homeobox genes are ancient, however, and the ext
Cleavage Luminescence from Cleaved Indium Phosphide

LI Dong-Guang,

中国物理快报 , 2008,

Kuang Guang-li,

中国物理 B , 1999,
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