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Search Results: 1 - 10 of 464245 matches for " Lawrence A. Olatunji "
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Effects of aqueous extract of Hibiscus sabdariffa on renal Na+-K+-ATPase and Ca2+-Mg2+-ATPase activities in Wistar rats
Lawrence A. Olatunji
Zhong Xi Yi Jie He Xue Bao , 2012,
Abstract: OBJECTIVE: To investigate the effects of oral administration of aqueous extract of Hibiscus sabdariffa on renal Na+-K+-ATPase and Ca2+-Mg2+-ATPase activities in rats.METHODS: The 25 and 50 mg/(kg·d) of aqueous extracts of H. sabdariffa were respectively given to rats in the experimental groups for 28 d, and rats in the control group received an appropriate volume of distilled water as vehicle. Na+-K+-ATPase and Ca2+-Mg2+-ATPase activities in the kidney were assayed by spectrophotometric method.RESULTS: Administrations of 25 and 50 mg/(kg·d) of aqueous extract of H. sabdariffa significantly decreased the Ca2+-Mg2+-ATPase activity in the kidney of rats (P<0.05). However, the renal Na+-K+-ATPase activity of the experimental rats was not affected by either dose of the extract. And the plasma Na+, K+ and Ca2+ levels of the experimental rats had no significant changes. Administration of either dose of the extract did not result in any significant changes in body and kidney weights, the concentrations of plasma albumin and total protein, and alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase activities. However, concentrations of creatinine and urea were significantly reduced by 50 mg/kg of the extract (P<0.05).CONCLUSION: The present study indicates that oral administration of aqueous extract of H. sabdariffa may preserve the renal function despite a decreased renal Ca2+-Mg2+-ATPase activity.
Evaluation of Tp-e Interval and Tp-e/QTc Ratio among Patients with Steady State Sickle Cell Disease  [PDF]
Olawale Mathias Akinlade, Adeseye Abiodun Akintunde, Olatunde Peter Olabode, Lawrence A. Olatunji, Oluwaseun Oyetope Akinpelu, Ayodele Olufemi Soladoye, Oladimeji George Opadijo
World Journal of Cardiovascular Diseases (WJCD) , 2019, DOI: 10.4236/wjcd.2019.96038
Abstract: Sickle cell disease (SCD) has been regarded as an inflammatory and pro-coagulatory disease with profound cardiovascular abnormalities including propensity for ventricular arrhythmogenesis. Tp-e and Tpe/QTc ratio however has?been proposed as better indicators of arrythmogenesis and has?been shown to be prolonged in many inflammatory conditions and correlate with levels of inflammatory markers. However, correlation between Tpe/QTc ratio and the level of highly sensitive C-reactive protein (hs-CRP) and plasminogen activator inhibitor (PAI) have not been reported in SCD. This study aims at evaluating Tp-e Interval and Tp-e/QTc ratio among steady state Sickle cell disease patients in relationship to the degree of anaemia, inflammatory and profibrotic markers.Methodology:?A cross-sectional hospital-based study comprises?30 sickle cell anaemia patients in steady state with anequal number of controls having genotype HbAA and HbAS respectively.Clinical, laboratory and ECG parameters were obtained.Results:?A total of 90 participants?are?with mean age 24.2
Contrators Risk Exposure in Public Educational Institution Projects in Nigeria
A.A. Olatunji
Journal of Engineering and Applied Sciences , 2012,
Abstract: The study investigated the various risks a contractor is exposed to while working on public institution projects in the Southern part of Nigeria. The study is aimed at determining the frequently occurring risks. In all, 75 questionnaires were administered to contractors by the means of one-to-one/face-to-face technique having identified the institutions to visit in the area. Data obtained for the study were analyzed using simple percentages and the mean score statistical tool. Based on the analysis of data from the field, the followings were the conclusions made from the study: Contractual risk comes first among the risk types which adversely affect contractors performance. Next to this is political risk which affects also the project cost and delay completion time in most cases. The study recommends that contingency fund for projects should be high to accommodate all types of risk on projects and that a known and documented process of awarding contract is adhered to.
Is There be Life Elsewhere in the Universe?
A.J. Olatunji
Online Journal of Earth Sciences , 2012, DOI: 10.3923/ojesci.2010.43.49
Abstract: One of the challenges facing scientists of today is how to unravel the mystery surrounding the origin of man, earth and the observable universe. It has taken them to the depth of the oceans, the earth s interior, the moon and other planets, proposal to visit the nearest stellar neighbor and explorations to the deepest parts of the universe. These challenges are as old as the primordial history of mankind himself and has continued to generate controversies among ordinary laymen, spiritualists, religious leaders and ever-increasing number of scientists world wide. This study describes salient aspects of the earth the solar system and galactic history. It explores the possibility of existence of life in other parts of the observable universe. The description is based on evidences from scientific discoveries, space probes, spiritual explanations, the spate of Unidentified Flying Objects (UFOs), the search for Extraterrestrial Intelligence (Project SETI), the possibility of Intelligent Design of the Universe (IDU) and the present state of earth man s knowledge and technology. The result of all explanations however showed that there is presently absence of evidence of life elsewhere in the universe. Though, man has not been able to establish whether there is evidence of absence of life elsewhere in the universe also. This is because man can still not predict clearly what could happen in future as man s knowledge and technology continues to increase.
Determination of Bond index of Birnin- Gwari Iron Ore in Nigeria  [PDF]
K.J. Olatunji, A.G. Durojaiye
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2010, DOI: 10.4236/jmmce.2010.97045
Abstract: Bond index is useful in designing of grinding system in mineral processing. In this study, the Bond work index of Birnin- Gwari iron ore in northern Nigeria is determined using modified Bond’s method using ‘reference ore’. Samples of iron ore were sourced using random method, reference minerals; marble and granite of known weight and iron ore of known weight were ground using the laboratory ball mill grinding machine. 80% passing size for the iron ore marble and granite samples were obtained at 100μm sieve size for the feeds and products. The work index of reference minerals; marble and granite were used to calculate the work index of iron ore. The value of 28.66 Kwh/short ton and 24.92 Kwh/short ton were obtained. The value of 20.39 Kwh/short ton was selected as it is within the range indicated by previous research work on iron ore in Nigeria.
Compositional Features and Industrial Assessment of Talcose Rocks of Itagunmodi-Igun Area, Southwestern Nigeria  [PDF]
J. O. Olajide-Kayode, O. A. Okunlola, A. S. Olatunji
Journal of Geoscience and Environment Protection (GEP) , 2018, DOI: 10.4236/gep.2018.61005
Abstract: Talcose rocks from Itagunmodi and Igun areas within the Ilesa Schist Belt, southwestern Nigeria, were studied to determine their compositional affinities and industrial properties. The talcose bodies occurred as lensoid enclaves closely associated with amphibolites and quartz-mica schist. Petrographic and X-ray diffraction-aided mineralogical studies reveal that the talcose rocks are of the talc-chlorite schist variety composed predominantly of talc (average 73.63%), subordinate chlorite (average 16.08%) and accessory lizardite (average 6.5%). Total whole rock characterization of the samples using Lithium Fusion digestion revealed high mean concentrations of SiO2 (57.53%), MgO (24.84%) and Fe2O3 (7.73%) with significant enrichment of Ni, Co and Cr; and low values of Ba, Rb, Sr, V, Cu and Pb. The talc-chlorite schists plotted in the peridotitic komatiite field of the Al2O3-(FeO + TiO2)-MgO diagram. Water Absorption Capacity ranges from 6.25% - 8.20%, Loss on Ignition is 4.8% - 6.1% while Linear Shrinkage is 1.25% - 1.70% and firing colour is brown to dark-brown. The overall compositional features of the talcose rocks of the area, which were hitherto uncharacterized, show their suitability as raw materials for paint, coloured pottery, ceramic insulation, textile, rubber and plastic manufacture with varying beneficiation requirements. Their high trace element content however, makes them unsuitable for use in pharmaceutical and cosmetic applications.
Propylethanoate Derivative from Coconut Coir
Ibidun James,A. Olatunji Gabriel,Atolani Olubunmi
Research Journal of Applied Sciences , 2012,
Abstract: The extraction of the mesocarpic fibre (coir) of dried coconut (Cocos nucifera) husk was carried out with n-hexane, ethyl acetate and ethanol in succession using soxhlet extraction method. The crude extract from the coir was separated into fractions using column chromatography and each fraction purified using thin layer chromatography tlc. The components were characterized with the aid of UV-Visible and FT-IR spectroscopic techniques. The structure of the isolated compound was elucidated using various techniques of 1H-NMR and 13C-NMR. The new compound, not yet reported in literature is identified as propyl (2-nitromethylphenyl) ethanoate.
Drowning in Data : VO to the rescue
A. Lawrence
Physics , 2009,
Abstract: Astronomical datasets are growing in size and diversity, posing severe technical problems. At the same time scientific goals increasingly require the analysis of very large amounts of data, and data from multiple archives. The Virtual Observatory (VO) initiative aims to make multiwavelength science and large database science as seamless as possible. It can be seen as the latest stage of a long term trend towards standardisation and collectivisation in astronomy. Within this inevitable trend, we can avoid the high energy style of building large fixed hierarchical teams, and keep the individualist style of astronomical research, if the VO is used to build a facility class data infrastructure. I describe how the VO works and how it may change in the Web 2.0 era.
Quasars, Starbursts, and the Cosmic Energy Budget
A. Lawrence
Physics , 2001,
Abstract: Observations in the far-infrared are the best way to make an unbiased survey of active galaxies in the loosest sense - but separating the true quasars from the starburst may be difficult. There is in fact much evidence to suggest that starburst and AGN activity are intimately connected, and FIRST will help us to explore this link. Since the last major FIRST conference in Grenoble, this issue has become even more central to modern astrophysics, with the realisation of the dominance of the FIR background, the discovery of high redshift SCUBA sources, and the emergence of the black hole mass deficit problem. What dominates the cosmic energy budget - nuclear fusion or accretion ?
The Ghost in the Machine
A. Lawrence
Physics , 2002,
Abstract: I examine simple tests for the presence of accretion disks in AGN - changes of surface brightness with viewing angle, changes of colour temperature with luminosity, and behaviour during variability. AGN observations pass the first two tests but fail the third, unless there is some previously unobserved source of heating - the ``ghost in the machine''.
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