oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Search Results: 1 - 10 of 248 matches for " Lawan Adamu "
All listed articles are free for downloading (OA Articles)
Page 1 /248
Display every page Item
Plasma Disposition of Ampicillin following Thiopentone Sodium Anaesthesia in Rabbits (Oryctolagus cuniculi)
S Sanni, FA Lawan, JY Adamu
Nigerian Veterinary Journal , 2011,
Abstract: Nigerian Veterinary Journal, Vol. 32(2): 2011; 97 - 101
Alterations in Biochemical, Hematological and Physical Parameters in Endurance Horses with Metabolic Crisis
Lawan Adamu,Noraniza,Rasedee Abdullah,Bashir Ahmad
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2012.4108.4114
Abstract: Metabolic crisis is the complex and detrimental physiological changes observed in eliminated endurance horses during endurance events. Therefore, this study aims to appraise the alterations in biochemical, hematological and physical parameters of endurance horses with metabolic crisis. About 174 endurance horses between the ages of 6-20 years were examined to be clinically healthy pre-ride and 115 were eliminated post-race as a result of metabolic crisis. Blood sample was collected and physical examinations were conducted at pre and post ride. The blood sample was analyzed for biochemical and hematological parameters. The parameters were assessed using one-way analysis of variance. Metabolic crisis leads to significant increases in heart rate (p<0.0001), capillary refill time (p<0.005) and significant decrease in gut motility (0.006). There were significant increases in RBC, Hb and PCV at (p<0.0001). There were also significant increases in WBC (p<0.0002), band neutrophil (p<0.012), segmented neutrophil (p<0.0001) and monocytes (p<0.011). Significant decreases were seen in sodium (p<0.0196) and chloride (p<0.0001). Significant increases were also assessed in plasma protein (p<0.0001), albumin (p<0.0001), lactate (p<0.0001), creatine kinase (p<0.0033), uric acid (p<0.0017), gamma glutamyl transferase (p<0.0472), urea (p<0.0014), triglyceride (p<0.0041), total protein (p<0.0001), icterus index and bilirubin (p<0.0024). Thus, these changes could be indicative of metabolic crisis and poor performance in endurance horses.
Effects of time of meat purchase on the level of microbial contamination of beef from retail points in Samaru market, Zaria-Nigeria
MK Lawan, A Temala, M Bello, J Adamu
Sokoto Journal of Veterinary Sciences , 2011,
Abstract: The meat retail selling points are the major places where people usually purchase meat from morning through to evening at retail points in Samaru, Zaria. A total of 100 meat samples were collected from five different retail meat selling points in Samaru market Zaria, Kaduna state. Twenty samples were obtained from each retail point (10 samples in the morning and 10 in the evening). The meat samples were tested for total aerobic and coliform plate counts to determine the effect of time on the level of microbial contamination. The result of the study shows that there was a statistically significant difference (P<0.05) between the aerobic plate counts of samples obtained in the morning and those of samples obtained in the evening. Similarly, there was a statistically significant difference (P<0.05) between the total coliform counts of the morning and evening samples. This suggests that there were increases in both total aerobic and coliform plates counts from the morning samples compared to evening samples. The minimum aerobic plate counts (6.0 log10 CFU/g) obtained exceeded the permissible value of (5.7log10 CFU/g) while minimum coliform counts (4.7 log10 CFU/g) exceeded the permissible value of (2.7 log10 CFU/g). This is of serious public health concern. It was concluded that there were increases in level of total aerobic and coliform counts in the meat samples obtained in the evening compared to those obtained in the morning and the minimum counts of both aerobic and coliform counts in morning and evening samples exceeded the minimum acceptable level in all the five retail points. The study demonstrated that it is better to purchase meat from retail points in the morning than evening because of the observed increase in microbial loads in the evening samples which increases the chances of meat-borne infection to consumers.
Changes in Biochemical, Hematological and Cytokine in Endurance Horses with Metabolic Crises
Lawan Adamu,Noraniza Mohd Adzahan,Rasedee Abdullah,Bashir Ahmad
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2012.3431.3436
Abstract: Metabolic crises are the convoluted and injurious physiological changes observed in eliminated endurance horses during endurance races. Therefore, this study aims to evaluate the changes in biochemical hematological and cytokine in endurance horses with metabolic crises. The 32 endurance horses between the ages of 6-20 years and weighing between 350-450 kg were examined to be clinically healthy pre-ride. The 16 horses were eliminated post-race as a result of metabolic crises. Blood sample were collected at pre and post ride. The blood samples were analyzed for biochemical, hematological and cytokine. The parameters were assessed using one-way analysis of variance. There were significant increases in RBC, Hb and PCV (p<0.0001). There were significant increases in MCV (p<0.0104) and a significant decrease in MCHC (p<0.0039). There were significant increases in WBC segmented neutrophil and monocytes (p<0.0001). Band neutrophil (p<0.0003) and lymphocytes (p<0.0043). There was a significant increase in IL-6 (p<0.0004). Significant decreases were observed in sodium and potassium (p<0.0001) and chloride (p<0.0004) while significant increases were also assessed in total protein, urea, lactate and creatine kinase (p<0.0001) AST (p<0.0049) glucose (p<0.0207) plasma protein and uric acid (p<0.0014). In conclusion metabolic crises are the major causes of eliminations and poor performance in endurance horses. Thus, this study aims to evaluate the biochemical, hematological and cytokine as indicative of metabolic crises and poor performance in endurance horses.
Polymerase Chain Reaction Detection of C. pseudotuberculosis in the Brain of Mice Following Oral Inoculation
Faez Firdaus Jesse,Lawan Adamu,Abdinasir Yusuf Osman,Ahmad Fauzan Bin Muhdi
International Journal of Animal and Veterinary Advances , 2013,
Abstract: The aim of present study was to detect the presence of C. pseudotuberculosis in the brain of the mice following oral inoculation as a model using PCR. Caseous lymphadenitis is a chronic and subclinical disease of sheep and goats which has universal distributions, presenting enormous animal and flock prevalence. Total of 16 mice were used for this study, 8 mice were inoculated orally with 1.0 mL sterile phosphate buffered saline pH 7, while another 8 mice were inoculated with 1.0 mL of 109 colony forming unit of C. pseudotuberculosis. Seven different organs were collected during post mortem for the detection ofC. pseudotuberculosis The result indicated 3 positive samples in lymph nodes, 5 in the brain and 1 in the liver. The PCR used in the present study may successfully be applied for the detection and diagnosis of C. pseudotuberculosis in the brain of the mice following oral inoculation.
Comparative performance of HbA1c 6.5% for FPG ≥ 7.0 vs 2hr PG≥ 11.1 criteria for diagnosis of Type 2 diabetes
AN Adamu
African Health Sciences , 2011,
Abstract: Background: International expert committee on the use of HbA1c to diagnose diabetes mellitus in 2009 and World Health Organization (WHO) in 2011 has advocated the use of HbA1c to diagnose diabetes mellitus. Objective: To determine and compare the relationship between the new cut off value of HbA1c with established criteria. Methods: Thirty-one hypertensive subjects attending Lagos University Teaching Hospital were recruited for HbA1c and standard oral glucose tolerance test. Fasting plasma glucose (FPG) and two-hour plasma glucose (2hrpp) value of e”126mg/dl and >200mg/dl were used as standard respectively for diagnosis of diabetes. The HbA1c of e”6.5% was used to diagnose diabetes. The performance and correlation of HbA1c with FPG and 2hrpp were calculated and results were compared. Results: Mean age of the subjects was 53.97±6.27years. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), efficiency and correlation of FPG is 50%, 68%, 27%, 85%, 64% and 0.5 respectively while the sensitivity, specificity, PPV, NPV, efficiency and correlation of 2hrpp is 73.91%, 62.5%,85%, 41.66%, 70.97% and 0.73% respectively. There was a significant difference between FPG and 2hrpp interms of sensitivity, PPV and NPV. Conclusion: The results of HbA1c with 2hrpp has better correlation, sensitivity, and PPV compared to HbA1c with FPG.
Pattern of Presentation and Outcome of Surgical Management of Primary Open Angle Glaucoma in Kano, Northern Nigeria
A Lawan
Annals of African Medicine , 2007,
Abstract: Background: Primary open angle glaucoma (POAG) is one of the leading causes of avoidable blindness. Unlike blindness from cataracts, glaucomatous optic nerve damage is irreversible, and prevention of glaucoma is one of the priorities of World Health Organization (WHO) Vision 2020 program. POAG is the commonest type of glaucoma and affects about 33.1 million people worldwide. This study is a five year review of 71 eyes of 63 patients who had trabeculectomy. The study evaluates the pattern of presentation and modality of surgical treatment in our environment. Methods: Records of all patients with primary open angle glaucoma operated over a five year period was retrieved. Information extracted included patients bio data, visual acuity, gonioscopic findings, intra ocular pressure as measured with applanation tonometer before and after surgery, and recorded in mmHg. Perimetry was done with 2 m tangent screen and recorded in a perimetry chart. All the patients had trabeculectomy with application of anti metabolite (5fluorouracil). Extra capsular cataract extraction with or, without posterior chamber intra ocular lens implantation was done on 13 patients. Biometry was not done on patients with cataract. Surgery was done on better eye first in all patients. Results: There were 71 eyes of 63 patients. The male to female ratio was 3:1. The age ranged between 18 to 75 years. 8 patients were below the age of 30 years. One third of the patients were between the ages of 50 to 59 years. At presentation 12 patients (19%) had normal vision (WHO vision category O), 26 patients (41%) were visually impaired, 12 patients (19%) were severely visually impaired and 13 patients (21%) were blind (from co existing cataracts). The cup disc(c: d) ratio assessed before surgery was 0.5 in 9 eyes (13%), 31 eyes (53%) had c: d ratio 0.6 to 0.8 and 18 eyes had c: d ratio of 0.9. All the patients had open anterior chamber angles (Schafer grade 3 and 4). Perimetric changes were; mild peripheral constriction in 5 eyes (8%), peripheral constriction with arcuate scotoma in 19 eyes (26%), constricted fields of 30° or less in 34 eyes (48%), and in 13 eyes there was inability to fixate on target. IOP before surgery was 21 to 30 mm Hg in 12 eyes (17%), and above 31 mm Hg in 69 eyes (83%). Post operative IOP of 10 to 15 mm Hg was obtained in 58 eyes (82%) and 11 eyes (15%) had IOP of 16 to 20 mm Hg. Only 2 eyes (3%) had IOP in the lower twenties. Conclusion: Primary open angle glaucoma is characterized by late presentation. Trabeculectomy with application of 5FU is the surgical treatment of choice in our environment and give good intra ocular pressure control. There is need to increase public awareness on glaucoma to limit this type of avoidable blindness
Results of Cataract Outreach Services in a State of Nigeria
Abdu Lawan
TAF Preventive Medicine Bulletin , 2010,
Abstract: AIM: A blindness prevalence survey in 1996 indicated that estimates of 40000 are blind from cataracts in Kano state, northwestern Nigeria. Many more were severely visually impaired. Eye care personnel and other resources for eye care delivery are located at the state capital. The state Ministry of Health organized an outreach program. The aim was to operate on 750 cataract patients and measure the visual acuity at two weeks follow up. METHOD: Patients were registered and examined. Cataract patients with accurate four quadrant light projection, briskly reacting pupils and normal intra ocular pressures were selected and had manual extra capsular cataract extraction with posterior chamber intra ocular lens implantation. Post operative medications were administered. Patients were reviewed at 2 weeks follow up after discharge during which their visual acuity was measured and recorded. RESULTS: 868 cataract patients were operated. Thirty two percent of the patients were blind before surgery and 77% of these had bilateral cataracts. The proportion of those who had posterior chamber intra ocular lens (PC IOL) was 85%. The proportion of patients who regained normal vision was 43% and overall, 94% had vision of 6/60 or, better after surgery compared with 20% in this category before surgery, (WHO vision category 0 and 1). CONCLUSION: Cataract outreach service is essential in reducing cataract blindness. There is need to follow up patients although the vision recorded for this study was obtained at two weeks follow up. [TAF Prev Med Bull 2010; 9(3): 225-228]
Pattern of presentation and outcome of surgical management of primary open angle glaucoma in Kano, Northern Nigeria
Lawan A
Annals of African Medicine , 2007,
Abstract: Background : Primary open angle glaucoma (POAG) is one of the leading causes of avoidable blindness. Unlike blindness from cataracts, glaucomatous optic nerve damage is irreversible, and prevention of glaucoma is one of the priorities of World Health Organization (WHO) Vision 2020 program. POAG is the commonest type of glaucoma and affects about 33.1 million people worldwide. This study is a five year review of 71 eyes of 63 patients who had trabeculectomy. The study evaluates the pattern of presentation and modality of surgical treatment in our environment. Methods : Records of all patients with primary open angle glaucoma operated over a five year period was retrieved. Information extracted included patients bio data, visual acuity, gonioscopic findings, intra ocular pressure as measured with applanation tonometer before and after surgery, and recorded in mmHg. Perimetry was done with 2 m tangent screen and recorded in a perimetry chart. All the patients had trabeculectomy with application of anti metabolite (5fluorouracil). Extra capsular cataract extraction with or, without posterior chamber intra ocular lens implantation was done on 13 patients. Biometry was not done on patients with cataract. Surgery was done on better eye first in all patients. Results : There were 71 eyes of 63 patients. The male to female ratio was 3:1. The age ranged between 18 to 75 years. 8 patients were below the age of 30 years. One third of the patients were between the ages of 50 to 59 years. At presentation 12 patients (19%) had normal vision (WHO vision category O), 26 patients (41%) were visually impaired, 12 patients (19%) were severely visually impaired and 13 patients (21%) were blind (from co existing cataracts). The cup disc(c: d) ratio assessed before surgery was 0.5 in 9 eyes (13%), 31 eyes (53%) had c: d ratio 0.6 to 0.8 and 18 eyes had c: d ratio of 0.9. All the patients had open anterior chamber angles (Schafer grade 3 and 4). Perimetric changes were; mild peripheral constriction in 5 eyes (8%), peripheral constriction with arcuate scotoma in 19 eyes (26%), constricted fields of 30° or less in 34 eyes (48%), and in 13 eyes there was inability to fixate on target. IOP before surgery was 21 to 30 mm Hg in 12 eyes (17%), and above 31 mm Hg in 69 eyes (83%). Post operative IOP of 10 to 15 mm Hg was obtained in 58 eyes (82%) and 11 eyes (15%) had IOP of 16 to 20 mm Hg. Only 2 eyes (3%) had IOP in the lower twenties. Conclusion : Primary open angle glaucoma is characterized by late presentation. Trabeculectomy with application of 5FU is the surgical treatment of c
Epidemiological Properties of Primary Open Angle Glaucoma in Nigeria
Lawan Abdu
Journal of Ophthalmology , 2013, DOI: 10.1155/2013/402739
Abstract: Background. Primary open angle glaucoma (POAG) is progressive chronic optic neuropathy in adults in which intraocular pressure (IOP) and other currently unknown factors contribute to damage. POAG is the second commonest cause of avoidable blindness in Nigeria. Pattern of Presentation. POAG is characterized by late presentation. Absence of pain which is a driving force for seeking medical help, inadequacy of trained eye care personnel, paucity of facilities, misdistribution of resources, lack of awareness, poor education, and poverty may all contribute to this. Medical and surgical treatment options available are challenging and tasking. Screening for Glaucoma. Screening is the presumptive identification of unrecognized disease (POAG) by applying test(s) which can be applied rapidly. Such test(s) should be of high reliability, validity, yield, acceptable, and cost effective. The test should ideally be sensitive, specific, and efficient. It is difficult to select a suitable test that meets these criteria. Intraocular pressure (IOP) appears to be the easiest option. But, high IOP is not diagnostic nor does normal value exclude the disease. Health education is a possible strategy in early case detection and management. Treatment of POAG. Glaucoma treatment can either be medical or surgical (this includes laser). Considering unavailability, potency, cost, and long-term effects of medication, surgery (trabeculectomy) could be a better option. Laser trabeculoplasty is available in a few centers. Viscocanalostomy is not routinely performed. Patient education is vital to success as management is for life. Conclusion. POAG remains a cause of avoidable blindness in Nigeria. There is need for long-term strategy to identify patients early and institute prompt management. Improvement in training of eye care personnel and provision of up to date equipment is essential in achieving this goal. 1. Introduction Primary open angle glaucoma (POAG) is progressive chronic optic neuropathy in adults in which intraocular pressure (IOP) and other currently unknown factors contribute to damage and in which in the absence of other identifiable causes, there is characteristic acquired atrophy of the optic nerve and loss retinal ganglion cells and their axons [1]. POAG has been associated with risk factors such as central corneal thickness, structure of the optic nerve head, age, genetic factors, race, and intraocular inflammation among others. The global estimate of people with glaucomatous optic neuropathy is 60 million, and 8.4 million are blind from the disease. The highest
Page 1 /248
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.