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Search Results: 1 - 10 of 4773 matches for " Laurent Turchi "
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Early Gene Expression in Wounded Human Keratinocytes Revealed by DNA Microarray Analysis
Manal A. Dayem,Chimène Moreilhon,Laurent Turchi,Virginie Magnone,Richard Christen,Gilles Ponzio,Pascal Barbry
Comparative and Functional Genomics , 2003, DOI: 10.1002/cfg.239
Abstract: Wound healing involves several steps: spreading of the cells, migration and proliferation. We have profiled gene expression during the early events of wound healing in normal human keratinocytes with a home-made DNA microarray containing about 1000 relevant human probes. An original wounding machine was used, that allows the wounding of up to 40% of the surface of a confluent monolayer of cultured cells grown on a Petri dish (compared with 5% with a classical ‘scratch’ method). The two aims of the present study were: (a) to validate a limited number of genes by comparing the expression levels obtained with this technique with those found in the literature; (b) to combine the use of the wounding machine with DNA microarray analysis for large-scale detection of the molecular events triggered during the early stages of the wound-healing process. The time-courses of RNA expression observed at 0.5, 1.5, 3, 6 and 15 h after wounding for genes such as c-Fos, c-Jun, Egr1, the plasminogen activator PLAU (uPA) and the signal transducer and transcription activator STAT3, were consistent with previously published data. This suggests that our methodologies are able to perform quantitative measurement of gene expression. Transcripts encoding two zinc finger proteins, ZFP36 and ZNF161, and the tumour necrosis factor α-induced protein TNFAIP3, were also overexpressed after wounding. The role of the p38 mitogen-activated protein kinase (p38MAPK) in wound healing was shown after the inhibition of p38 by SB203580, but our results also suggest the existence of surrogate activating pathways.
La pronuncia della Grande Chambre della Corte di Strasburgo sul caso Lautsi C. Italia: post nubila Phoebus
Vincenzo Turchi
Stato, Chiese e Pluralismo Confessionale , 2011,
Abstract: SOMMARIO: 1. Premessa - 2. La giurisdizione domestica sul caso Lautsi - 3. La sentenza della Seconda Sezione della Corte - 4. La sentenza della Grande Chambre - 5. Laicità al plurale - 6. Metagiuridica del crocifisso.
New tools, new vision: Telling the next story
Peter Turchi
lo Squaderno , 2010,
Abstract: Since Maps of the Imagination, a book exploring the relationship between mapmaking and writing, was published in 2004, any number of people have asked me if recent developments in mapping have correlations in contemporary storytelling.
Knowledge Expansion of a Statistical Machine Translation System using Morphological Resources
Turchi, Marco;Ehrmann, Maud;
Polibits , 2011,
Abstract: translation capability of a phrase-based statistical machine translation (pbsmt) system mostly depends on parallel data and phrases that are not present in the training data are not correctly translated. this paper describes a method that efflciently expands the existing knowledge of a pbsmt system without adding more parallel data but using external morphological resources. a set of new phrase associations is added to translation and reordering models; each of them corresponds to a morphological variation of the source/target/both phrases of an existing association. new associations are generated using a string similarity score based on morphosyntactic information. we tested our approach on en-fr and fr-en translations and results showed improvements of the performance in terms of automatic scores (bleu and meteor) and reduction of out-of-vocabulary (oov) words. we believe that our knowledge expansion framework is generic and could be used to add different types of information to the model.
Memórias da tragédia: masculinidade e envelhecimento na Copa do Mundo de 1950
Pacheco, Leonardo Turchi;
Revista Brasileira de Ciências do Esporte , 2010, DOI: 10.1590/S0101-32892010000400003
Abstract: the intention of this article is to reflect on the making of the masculinity and perceptions of ageing in the sport field through the 1950's world cup's remembrances. in order to reveal the discourses produced by the written media were used as documents the estado de minas journal, o cruzeiro magazine and the accounts of actors that somehow attended and/or wrote about the event. we point out that although the main accusations made to justify the defeat were linked to racial deficiency and virility loss, other accusations so important as the previous were inexplicably forgotten, such as the ageing deficiency and shame
Signótica , 1999, DOI: 10.5216/sig.v11i1.7268
Abstract: O artigo procura compreender a rela o entre poesia e história em Romanceiro da Inconfidência, de Cecília Meireles, estabelecida pelo poder da metáfora. The article aims to understand the relation between poetry and history in Romanceiro da Inconfidência, by Cecília Meireles, established by metaphor’s power.
Maria Zaira Turchi
Signótica , 1990, DOI: 10.5216/sig.v2i1.7225
Abstract: A corrente de suspense na Literatura Infan -til e Juvenil Brasileira bastante f rtil, tendo em Jo £o Carlos Marinho um de seus representantes mais importantes. O presente ensaio volta-se para o estudo de sua obra, O g anio do crime, mostrando como e por que se pode consider -lo uma narrati -va de suspense a op § £o intermedi ria entre o ro -mance policial cl ssico, de enigma, e o romance, "s rie negra". O estudo se prop μe, ainda, a mos -trar como o romance, atr s do suspense que prende o jovem leitor, vai promover uma cr -tica ir ′nica e bem humorada a quest μes de nossa realidade so -cial. The suspense trend in the Brazilian Litera -tura for Youth is largely used and Jo £o Carlos Ma -rinho is one of its most important representatives. The present essay deals with the study of his work O g anio do crime, showing how and why this no -vel can be considered a narrative of suspense, pla-ced between the classical mistery novel, and the so called "black series" novel. This study intends al-so to reveal that behind the suspense that touches the young reader, the novel makes as well ironical and good humoured criticism of aspects of our so -cial reality.
As faces do amor em Otelo The faces of love in Othello
Maria Zaira Turchi
Signótica , 2010, DOI: 10.5216/sig.v22i1.12746
Abstract: O artigo analisa como em Otelo, de Shakespeare, as rela es entre amor, sexualidade, casamento representam o centro da investiga o da tragédia, num conflito que envolve amor espiritual e amor carnal – processo de idealiza o e de degrada o. The article analyses how in Shakespeare’s play Othello the relations among love, sexuality, marriage represent the heart of the tragedy, in a conflict that envolves spiritual love and sexual love – idealization and degradation.
Qualidade de vida: compromisso histórico da epidemiologia
Martelli Celina Maria Turchi
Cadernos de Saúde Pública , 1995,
O pulo do gato da pequena indústria precária
Noronha, Eduardo G.;Turchi, Lenita;
Tempo Social , 2007, DOI: 10.1590/S0103-20702007000100013
Abstract: this paper presents the main research findings of a study conducted in two industrial districts and what i refer to here as local industrial arrangements - lias. the research focuses on the transition from a situation characterized by informal or illegal production, low wages and precarious work conditions, to one characterized by high levels of productivity/quality/fair labour conditions. the findings of the empirical study reveal the importance of specific institutions in the transition from a widespread informality to the more stable and sustainable situation of the lias. in the case of jaraguá (go), it was the legal framework that enabled this change and the subsequent impact on local development, while in the case of toritama (pe), transition was stimulated by the cooperation between legal and environmental institutions.
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