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Search Results: 1 - 10 of 235996 matches for " Laura R; Palma-Coca "
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Encuesta Nacional de Cobertura de Vacunación (influenza, neumococo y tétanos) en adultos mayores de 60 a?os en México
Trejo-Valdivia,Belem; Mendoza-Alvarado,Laura R; Palma-Coca,Oswaldo; Hernández-ávila,Mauricio; Téllez-Rojo Solís,Martha María;
Salud Pública de México , 2012, DOI: 10.1590/S0036-36342012000100006
Abstract: objective: determine vaccination coverage (vc) among adults 60 years of age and older (ep), for influenza, pneumococcal and tetanus vaccines, association with socio-demographic characteristics and heterogeneity at state level. material and methods: cross-sectional analysis based on information from 18 015 households visited in a national survey. general and vaccine information (self-report) for a randomly selected elder in each household is available. results: the national vc level was found to be 56.5% (±0.97) for influenza, 44.3% (±0.98) for pneumococcus and 61.8% (±0.96) for tetanus. the vc was significantly lower for ep without health social services and higher for women. almost 20.0% of ep recognized not having vaccines at all, due mainly that they didn't know it was a duty. conclusions: important improvements are shown in vaccination coverage among elderly in mexico. differentials suggest the need to intensify information campaigns and actions that could improve the accessibility to vaccines for this population.
Prevalencia de accidentes de tránsito no fatales en México: resultados de la ENSANUT 2006
ávila-Burgos,Leticia; Medina-Solís,Carlo E; Pérez-Nú?ez,Ricardo; Híjar-Medina,Martha; Aracena-Genao,Belkis; Hidalgo-Solórzano,Elisa; Palma-Coca,Oswaldo;
Salud Pública de México , 2008, DOI: 10.1590/S0036-36342008000700007
Abstract: objective: to determine non-fatal road traffic injuries (nfrti) prevalence and its distribution in mexico. material and methods: data from ensanut survey 2006 were used. using simple random sampling, one adult, one adolescent and one child were selected in each household, constituting a final sample of 94 197 representing an n of 102 886 482 people. the dependent variable was the prevalence of road traffic injuries (rti) during the 12 months prior to the survey. results: the general accident prevalence was 6.0%; 16.7% corresponded to nfrti. men in the 20 to 44 age group living in urban areas and with high socioeconomic status had a higher rti prevalence (p<0.05). jalisco, aguascalientes and sonora were states with the highest prevalence of rti, while guerrero, michoacan and oaxaca were those with the lowest. conclusions: nfrti are frequent in mexico and they are concentrated among men in productive ages in urban areas; they are associated with socioeconomic status at the individual level and with the state's development at the population level.
A versatile vector system for generating recombinant EGFP-tagged proteins in yeast  [PDF]
Francesco Palma, Laura Chiarantini
Advances in Bioscience and Biotechnology (ABB) , 2011, DOI: 10.4236/abb.2011.21003
Abstract: This paper reports a versatile egfp-tagged pFL61-based expression vector system which allows the production on yeast of homo- and heterologous proteins fused with the Enhanced Green Fluorescent Protein (EGFP) at the C-terminus. This expression system, which involves a fluorescent protein, readily allows both to verify the expression and to localize the protein in the yeast cell. The vector carries a Not I site upstream the first codon of the egfp gene. The yeast cells harbouring this plasmid emit a feeble emission compared to the fluorescence expected. Was then investigated the effect of the Not I site, located very close to the start codon, on the expression of the reporter egfp gene using northern and western blotting, fluorescence microscopy and flow cytometry. Data indicated that this palindromic site could hide the start codon so as to negatively affect translation. This aspect confers to the proposed expression system an advantage in distinguishing clones after transformation.
Frecuencia y pesquisa de síntomas en pacientes crónicos en fases avanzadas en un hospital clínico: Existe concordancia entre pacientes y médicos? Frequency and assessment of symptoms in hospitalized patient with advanced chronic diseases: Is there concordance among patients and doctors?
Alejandra Palma,Ignacia del Río,Pilar Bonati,Laura Tupper
Revista médica de Chile , 2008,
Abstract: Physicians tend to over or underestimate symptoms reported by patients. Therefore standardized symptom scoring systems have been proposed to overcome this drawback. Aim: To estimate the prevalence and the diagnostic accuracy of physical and psychological symptoms and delirium in patients admitted to an internal medicine service at a university hospital. Material and Methods: We studied 58 patients, 45 with metastasic cancer and 13 with other advanced chronic diseases. The following scales were used: the Confusion Assessment Method for the diagnosis of delirium; the Edmonton Symptom Assessment Scale (ESAS) for pain and other physical symptoms; the Hospital Anxiety and Depression Scale to assess anxiety and depression. The ESAS was simultaneously applied to patients without delirium and their doctors to assess the level of diagnostic concordance. Results: Twenty two percent of patients had delirium. Among the 45 patients without delirium, 11 (25%) had at least eight symptoms and 39 (88.6%) had four symptoms. The prevalence of symptoms was very high, ranging from 22 to 78%. Pain, restlesness, anorexia and sleep disorders were the most common. The concordance between symptoms reported by patients and those recorded by doctor was very low, with a Kappa index between 0.001 and 0.334. Conclusions: In our sample of chronic patients, there is a very high frequency of psychological and physical symptoms that are insufficiently recorded by the medical team
ACTUALIDAD DEL CONCEPTO DE PHYLUM EN ZUBIRI
COCA,JUAN R;
Ideas y Valores , 2008,
Abstract: the aim of this article is to analyze zubiri’s concept of phylum. for this purpose, i analyze the meaning of phylum for zubiri and that of biological phylum, explaining the validity of the former with respect to the latter. the consequences of this concept for evolutionary theory are also presented.
Frecuencia y pesquisa de síntomas en pacientes crónicos en fases avanzadas en un hospital clínico: ?Existe concordancia entre pacientes y médicos?
Palma,Alejandra; del Río,Ignacia; Bonati,Pilar; Tupper,Laura; Villarroel,Luis; Olivares,Patricia; Nervi,Flavio;
Revista médica de Chile , 2008, DOI: 10.4067/S0034-98872008000500003
Abstract: physicians tend to over or underestimate symptoms reported by patients. therefore standardized symptom scoring systems have been proposed to overcome this drawback. aim: to estimate the prevalence and the diagnostic accuracy of physical and psychological symptoms and delirium in patients admitted to an internal medicine service at a university hospital. material and methods: we studied 58 patients, 45 with metastasic cancer and 13 with other advanced chronic diseases. the following scales were used: the confusion assessment method for the diagnosis of delirium; the edmonton symptom assessment scale (esas) for pain and other physical symptoms; the hospital anxiety and depression scale to assess anxiety and depression. the esas was simultaneously applied to patients without delirium and their doctors to assess the level of diagnostic concordance. results: twenty two percent of patients had delirium. among the 45 patients without delirium, 11 (25%) had at least eight symptoms and 39 (88.6%) had four symptoms. the prevalence of symptoms was very high, ranging from 22 to 78%. pain, restlesness, anorexia and sleep disorders were the most common. the concordance between symptoms reported by patients and those recorded by doctor was very low, with a kappa index between 0.001 and 0.334. conclusions: in our sample of chronic patients, there is a very high frequency of psychological and physical symptoms that are insufficiently recorded by the medical team
Epidemiología y factores de riesgo asociados al botulismo de los alimentos y al botulismo infantil: Dónde y cuándo? Epidemiology and risk factors associated to foodborne and infant botulism: Where and when?
Mariela Tornese,M. Laura Rossi,Florencia Coca,Cecilia Cricelli
Revista chilena de infectología , 2008,
Abstract: La causa más frecuente de botulismo de los alimentos es la elaboración y consumo de conservas caseras, que son procesadas de manera inapropiada, creando un ambiente anaeróbico que favorece la supervivencia de las esporas, su germinación, reproducción y síntesis de toxina. Entre 1992 y 2003, se han notificado en Argentina 34 casos de botulismo transmitido por alimentos y 275 casos de botulismo infantil. La gravedad de los síntomas depende de la ingesta de esporas viables por el paciente. Formas leves de botulismo pueden no requerir asistencia médica en absoluto, por lo que si un paciente presenta sólo náuseas y ligeros síntomas neurológicos, existe la posibilidad de que un caso de botulismo pueda no ser diagnosticado. En Argentina, la mayoría de los casos de botulismo se relacionan con alimentos de preparación casera. Es importante para la prevención, educar a los consumidores, desincentivando la ingesta de este tipo de alimentos Foodborne botulism is caused by ingestión of a preformed toxin produced in food by C. botulinum. The most frequent source is home-canned foods, in which spores that survive an inadequate cooking and canning process germinate, reproduce, and produce this toxin in the anaerobic environment of the canned food. From 1992 to 2003, 34 cases of food-borne cases and 275 cases of infant botulism were reported in Argentina. The severity of symptoms depends on the amount of toxin ingested. Mild cases may not seek medical attention at all. A patient presenting only nausea and mild neurological symptoms may not raise the physician's attention and therefore the case will not be reported. It is important to make physicians aware of this potentially fatal disease. In Argentina, most botulism cases are related to home-canned food. Therefore, botulism can be prevented through the education of consumers in order to discourage the consumption of that kind of food
First case of Trichinosis caused by consumption of undercooked horse meat in Argentina
Laura Rossi, Florencia Coca, Cecilia Cricelli, Alcides Troncoso
Journal of Infection in Developing Countries , 2007,
Abstract: Background: Trichinellosis is a helminthic infection, which has a wide geographical distribution. It is acquired by ingestion of raw or undercooked meat infected with Trichinella spp.Methodology: The present work communicates an unusual cause of human trichinosis acquired by eating horse meat which occurred in Argentina. Laboratory investigations were conducted to confirm the diagnosis and rule out other infections including malaria and leptospirosis Result: The patient showed clinical symptoms and signs of trichinellosis such as fever, myalgias, conjunctivitis, palpebral and facial oedema. Laboratory test showed elevated eosinophilia. Anti-Trichinella antibodies in the patient’s sera investigated by EIA were reactive. Epidemiology, clinical findings and laboratory features were consistent with diagnosis of trichinellosis.Conclusions: Although the first case of trichinellosis associated with horsemeat was reported in Italy in 1975 and since then other cases of trichinellosis caused by horsemeat have been reported in Europe, there has been no previous experience of trichinellosis due to horsemeat in Argentina.
Misbehaviour of XIST RNA in Breast Cancer Cells
Silvia M. Sirchia, Silvia Tabano, Laura Monti, Maria P. Recalcati, Manuela Gariboldi, Francesca R. Grati, Giovanni Porta, Palma Finelli, Paolo Radice, Monica Miozzo
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0005559
Abstract: A role of X chromosome inactivation process in the development of breast cancer have been suggested. In particular, the relationship between the breast cancer predisposing gene BRCA1 and XIST, the main mediator of X chromosome inactivation, has been intensely investigated, but still remains controversial. We investigated this topic by assessing XIST behaviour in different groups of breast carcinomas and in a panel of breast cancer cell lines both BRCA1 mutant and wild type. In addition, we evaluated the occurrence of broader defects of heterochromatin in relation to BRCA1 status in breast cancer cells. We provide evidence that in breast cancer cells BRCA1 is involved in XIST regulation on the active X chromosome, but not in its localization as previously suggested, and that XIST can be unusually expressed by an active X and can decorate it. This indicates that the detection of XIST cloud in cancer cell is not synonymous of the presence of an inactive X chromosome. Moreover, we show that global heterochromatin defects observed in breast tumor cells are independent of BRCA1 status. Our observations sheds light on a possible previously uncharacterized mechanism of breast carcinogenesis mediated by XIST misbehaviour, particularly in BRCA1-related cancers. Moreover, the significant higher levels of XIST-RNA detected in BRCA1-associated respect to sporadic basal-like cancers, opens the possibility to use XIST expression as a marker to discriminate between the two groups of tumors.
Wild potato species (Solanum section Petota Solanaceae) in the Tunari National Park, Andean Region of Cochabamba, Bolivia  [PDF]
Mario Coca Morante, Alejandro Coca-Salazar
Open Journal of Ecology (OJE) , 2014, DOI: 10.4236/oje.2014.42004
Abstract:

The Tunari National Park is located in the Tunari Mountain Range, part of the Cochabamba Range in the Bolivian Andes. The Park is home to species of wild potato (Solanum section Petota Solanaceae), but these are now threatened by human activity. The aims of the present study were: 1) to determine the distribution of wild potato species in the Park, and, 2) to determine the size of their populations. Collection routes were established within the Park, and the species present along them recorded in 2006, 2007 and 2008. Their population sizes were determined in 2008. Four wild potato species were identified: S. capsicibaccatum, S. berthaultii, S. brevicaule and S. toralapanum. S. capsicibaccatum was the most abundant and had the most extensive distribution, followed by S. berthaultii; these last two species are likely endemic. The other species, although probably also endemic, were much less widely distributed; some limiting factor(s) would therefore appear to be acting upon them. S. berthaultii

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