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Search Results: 1 - 10 of 11820 matches for " Laura Milazzo "
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BIOLOGY OF HUMAN MALARIA PLASMODIA INCLUDING PLASMODIUM KNOWLESI
Spinello Antinori,Laura Galimberti,Laura Milazzo,Mario Corbellino
Mediterranean Journal of Hematology and Infectious Diseases , 2012, DOI: 10.4084/mjhid.2012.
Abstract: Malaria is a vector-borne infection caused by unicellular parasite of the genus Plasmodium. Plasmodia are obligate intracellular parasites that in humans after a clinically silent replication phase in the liver are able to infect and replicate within the erythrocytes. Four species (P.falciparum, P.malariae, P.ovale and P.vivax) are traditionally recognized as responsible of natural infection in human beings but the recent upsurge of P.knowlesi malaria in South-East Asia has led clinicians to consider it as the fifth human malaria parasite. Recent studies in wild-living apes in Africa have revealed that P.falciparum, the most deadly form of human malaria, is not only human-host restricted as previously believed and its phylogenetic lineage is much more complex with new species identified in gorilla, bonobo and chimpanzee. Although less impressive, new data on biology of P.malariae, P.ovale and P.vivax are also emerging and will be briefly discussed in this review.
Factors influencing the length of the incision and the operating time for total thyroidectomy
Fabrizio Consorti, Francesca Milazzo, Mariagiovanna Notarangelo, Laura Scardella, Alfredo Antonaci
BMC Surgery , 2012, DOI: 10.1186/1471-2482-12-15
Abstract: The aim of the study was to assess the correlation between incision length and operation duration with a set of biometric and clinical factors and establish a rationale for the decision on the length of incision in open surgery.Ninety-seven consecutive patients scheduled for total thyroidectomy were prospectively evaluated. All operations were performed by the same team and the surgeon decided the length of the incision according to his personal judgement. Patients who had previously undergone neck surgery were excluded.The length of the incision was strongly correlated with gender, thyroid volume, neck circumference and clinical diagnosis and weakly correlated with the body mass index. Operation duration was only weakly correlated with gender and neck circumference. Multiple linear regression revealed that the set of factors assessed explained almost 60?% of the variance in incision length but only 20?% of the variance in operation duration. When patients were classified according to the distribution of their thyroid volume, cases within one standard deviation of the mean did not show a significant difference in terms of operation duration with incisions of various lengths.Although thyroid volume was a major factor in driving the decision with respect to the length of the incision, our study shows that it had only minor effect on the duration of the operation. Many more open thyroidectomies could therefore be safely performed with shorter incisions, especially in women. Duration of the operation is probably more closely linked to the inherent technical difficulty of each case.The classical Kocher incision for thyroid surgery, which is approximately 10?cm long, has been the gold standard for more than a century. Since the introduction of Minimally Invasive (MI) surgery of the neck in the second half of the 1990s [1], several different techniques have been proposed, which have been classified as pure endoscopic techniques, video-assisted techniques and minimally inva
La Akrasia y el principio de continencia en davidson: Una actualización de su pensamiento
Milazzo,Rosario;
EPISTEME , 2008,
Abstract: this paper aims to inquire into the davidson?s conception of akrasia exposed in how is weakness of the will possible? (1966). davidson aims at theorizing about the dark problem of akrasia, which is characterized as an aristotelian conception. part of davidson?s strategy for facing the difficulties of this subject is to propose a separation of the problem from akrasia, the morality, since he argues that akrasia is a problem of the philosophy of action, not a problem of moral philosophy. in this context, davidson suggests the existence of a principle which orients the performance of rational man: the principle of continence. however, how to do that principle someone?s own remains unanswered. we will try to show, how the thought of davidson about this subject has evolved.
On upper chromatic number for SQS(10) and SQS(16)
Lorenzo Milazzo
Le Matematiche , 1995,
Abstract: A mixed hypergraph is characterized by the fact that it possesses anti-edges as well as edges. In a colouring of a mixed hypergraph, every anti-edge has at least two vertices of the same colour and every edge has at least two vertices coloured differently. The upper chromatic number X is the maximal number of colours for which there exists a colouring using all the colours. The concepts of mixed hypergraph and upper chromatic number are applied to STS and SQS. In fact it is possible to consider a Steiner system as a mixed hypergraph when all the blocks are anti-edges (Co-STSs, Co-SQSs) or at the same time edges and anti-edges (BSTSs, BSQSs). In this paper the necessary conditions in order to colour Co-STSs, BSTSs and Co-SQSs, BSQSs are given and the values of upper chromatic number for Co-SQS(10), BSQS(10) and for BSQSs(16), obtained from a doubling construction, are determined.
Common blocks for ASQS(12)
Lorenzo Milazzo
Le Matematiche , 1997,
Abstract: An ASQS(v) is a particular Steiner system featuring a set of v vertices and two separate families of blocks, B and G, whose elements have a respective cardinality of 4 and 6. It has the property that any three vertices of X belong either to a B-block or to a G-block. The parameter cb is the number of common blocks in two separate ASQSs, both defined on the same set of vertices X . In this paper it is shown that cb ≤ 29 for any pair of ASQSs(12).
Teaching Roman Law in Iceland
Milazzo, Francesco
Nordicum-Mediterraneum , 2006,
Abstract:
Gábor Hamza, Le développement du droit privé européen. Le r le de la tradition romaniste dans la formation du droit privé moderne (Budapest : Biblioteca Iuridica of E tv s Loránd University, 2005)
Milazzo, Nino
Nordicum-Mediterraneum , 2009,
Abstract:
Filippo Marotta Rizzo, Lu scavittu e altre novelle, with prefaces by Titta Scidà and Carlo Marullo di Condojanni (Catania: Maimone, 2004), pp. 79
Milazzo, Francesco
Nordicum-Mediterraneum , 2009,
Abstract:
Multifractal analysis of three-dimensional grayscale images: Estimation of generalized fractal dimension and singularity spectrum
Lorenzo Milazzo
Physics , 2013,
Abstract: A multifractal analysis is performed on a three-dimensional grayscale image associated with a complex system. First, a procedure for generating 3D synthetic images (2D image stacks) of a complex structure exhibiting multifractal behaviour is described. Then, in order to characterize the 3D system, the theoretical calculation of the generalized fractal dimension and two different approaches for evaluating the singularity spectrum are presented.
Within-Host Dynamics of the Hepatitis C Virus Quasispecies Population in HIV-1/HCV Coinfected Patients
Flavia Bernini,Erika Ebranati,Chiara De Maddalena,Renata Shkjezi,Laura Milazzo,Alessandra Lo Presti,Massimo Ciccozzi,Massimo Galli,Gianguglielmo Zehender
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0016551
Abstract: HIV/HCV coinfected individuals under highly active antiretroviral therapy (HAART) represent an interesting model for the investigation of the role played by the immune system in driving the evolution of the HCV quasispecies. We prospectively studied the intra-host evolution of the HCV heterogeneity in 8 coinfected subjects, selected from a cohort of 32 patients initiating HAART: 5 immunological responders (group A) and 3 immunological non-responders (group B), and in two HCV singly infected controls not assuming drugs (group C). For all these subjects at least two serial samples obtained at the first observation (before HAART) and more than 1 year later, underwent clonal sequence analysis of partial E1/E2 sequences, encompassing the whole HVR1. Evolutionary rates, dated phylogenies and population dynamics were co-estimated by using a Bayesian Markov Chain Monte Carlo approach, and site specific selection pressures were estimated by maximum likelihood-based methods. The intra-host evolutionary rates of HCV quasispecies was 10 times higher in subjects treated with HAART than in controls without immunodeficiency (1.9 and 2.3×10?3 sub/site/month in group A and B and 0.29×10?3 sub/site/month in group C individuals). The within-host Bayesian Skyline plot analysis showed an exponential growth of the quasispecies populations in immunological responders, coinciding with a peak in CD4 cell counts. On the contrary, quasispecies population remained constant in group B and in group C controls. A significant positive selection pressure was detected in a half of the patients under HAART and in none of the group C controls. Several sites under significant positive selection were described, mainly included in the HVR1. Our data indicate that different forces, in addition to the selection pressure, drive an exceptionally fast evolution of HCV during HAART immune restoration. We hypothesize that an important role is played by the enlargement of the viral replicative space.
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