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Search Results: 1 - 10 of 198009 matches for " Lalitha N "
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A Behavioral Model For Stock Prices
N Lalitha,D N Rao
Contemporary Issues and Ideas in Social Sciences , 2007,
Abstract: Multi-factor models have been popularly used to explainasset market behavior. The Fama and French three-factor modelfitted on the sample set of new economy stocks for the studyperiod of late nineties to early 2000s, however, fails to giveadequate explanation of the stock market behavior. A behavioralmodel built on the assumption of bounded rationality and biases ininvestor behavior seems to offer a better explanation of the stockprice behavior.
Development and validation of RP-HPLC method for estimation of Cefotaxime sodium in marketed formulations
Lalitha N,Sanjay Pai PN
Journal of Basic and Clinical Pharmacy , 2010,
Abstract: A RP-HPLC assay method has been developed and validated for cefotaxime. An isocratic RP-HPLC was developed on a SS Wakosil II- C8 column (250 mm ×4.6 mm i.d., 5 μm) utilizing a mobile phase of ammonium acetate buffer (pH 6.8) and acetonitrile (85:15 v/v) with UV detection at wavelength 252 nm at the flow rate 0 .8 ml/min. The proposed method was validated for sensitivity, selectivity, linearity, accuracy, precision, ruggedness, robustness and solution stability. The response of the drug was linear in the concentration range of 10-70 μg/ml. Limit of detection and Limit of quantification was found to be 0.3 μg/ml and 0.6 μg/ml respectively. The % recovery ranged within 97-102 %. Method, system, interday and intraday precision was found to be within the limits of acceptance criteria. Method was found to be rugged when analysis was carried out by different analyst. The method was found to be sensitive and efficient with 2216 theoretical plates, 0.1128 mm HETP and tailing factor 1. The method was suitable for the quality control of cefotaxime in injection formulations.
Analytical Solution for Bending Stress Intensity Factor from Reissner’S Plate Theory  [PDF]
Lalitha Chattopadhyay
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.35060
Abstract: Plate-type structural members are commonly used in engineering applications like aircraft, ships nuclear reactors etc. These structural members often have cracks arising from manufacture or from material defects or stress concentrations. Designing a structure against fracture in service involves consideration of strength of the structure as a function of crack size, dimension and the applied load based on principles of fracture mechanics. In most of the engineering structures the plate thickness is generally small and in these cases though the classical plate theory has provided solutions, the neglect of transverse shear deformation leads to the limitation that only two conditions can be satisfied on any boundary whereas we have three physical boundary conditions on an edge of a plate. In this paper this incompatibility is eliminated by using Reissner plate theory where the transverse shear deformation is included and three physically natural boundary conditions of vanishing bending moment, twisting moment and transverse shear stress are satisfied at a free boundary. The problem of estimating the bending stress distribution in the neighbourhood of a crack located on a single line in an elastic plate of varying thickness subjected to out-of-plane moment applied along the edges of the plate is examined. Using Reissner’s plate theory and integral transform technique, the general formulae for the bending moment and twisting moment in an elastic plate containing cracks located on a single line are derived. The thickness depended solution is obtained in a closed form for the case in which there is a single crack in an infinite plate and the results are compared with those obtained from the literature.
A Cluster of Cases of Mycobacterium chelonei Keratitis following Penetrating Keratoplasty
Srinivasan M,Prajna Lalitha,Prajna N Venkatesh
Indian Journal of Ophthalmology , 2005,
Abstract: Cluster infection with Mycobacterium chelonei following penetrating keratoplasty is described. All the donor eyes were harvested from the same collection centre. This underscores the importance of adherence to sterile protocols.
Codes with Locality for Two Erasures
N. Prakash,V. Lalitha,P. Vijay Kumar
Computer Science , 2014,
Abstract: In this paper, we study codes with locality that can recover from two erasures via a sequence of two local, parity-check computations. By a local parity-check computation, we mean recovery via a single parity-check equation associated to small Hamming weight. Earlier approaches considered recovery in parallel; the sequential approach allows us to potentially construct codes with improved minimum distance. These codes, which we refer to as locally 2-reconstructible codes, are a natural generalization along one direction, of codes with all-symbol locality introduced by Gopalan \textit{et al}, in which recovery from a single erasure is considered. By studying the Generalized Hamming Weights of the dual code, we derive upper bounds on the minimum distance of locally 2-reconstructible codes and provide constructions for a family of codes based on Tur\'an graphs, that are optimal with respect to this bound. The minimum distance bound derived here is universal in the sense that no code which permits all-symbol local recovery from $2$ erasures can have larger minimum distance regardless of approach adopted. Our approach also leads to a new bound on the minimum distance of codes with all-symbol locality for the single-erasure case.
Stability-Indicating Reverse Phase HPLC Method for the Determination of Cefazolin
N Lalitha, P Sanjay, M.G Vyshak, U Kadri
Tropical Journal of Pharmaceutical Research , 2010,
Abstract: Purpose: The aim of the present study was to establish the inherent stability of cefazolin through stress studies under a variety of ICH recommended test conditions and, also to develop a stability indicating assay. Methods: A stability-indicating HPLC assay method was developed and validated for cefazolin using an isocratic RP-HPLC method which employed an SS Wakosil II- C18 column (250 mm × 4.6 mm i.d., 5 μm) with a mobile phase consisting of phosphate buffer (pH 6.8) and methanol (5:2 v/v), and UV detection at 254 nm at a flow rate of 1 ml/min. The stress testing of cefazolin was carried out under acidic, alkaline, neutral, oxidation and thermal conditions. Results: The drug peak was well resolved from the peaks of the degradation products. The proposed method was validated for sensitivity, selectivity, linearity, accuracy, precision and solution stability. From the degradation studies it was found that the drug was thermally stable but unstable in acidic, alkaline, neutral and oxidative conditions. The response of drug was linear in the concentration Range of 1 - 50 μg/ml with the number of theoretical plates, and tailing factor being 1341 and 1, respectively. Limit of detection and limit of quantification were 0.1 and 0.2, μg/ml respectively while recovery ranged from 95 - 100%. Method precision and precision of the system were within the limits of acceptance criteria. Conclusion: This study presents a simple and validated stability-indicating HPLC method for the estimation of cefazolin in the presence of degradation products. The developed method is specific, accurate, precise and robust. All the degradation products formed during forced degradation studies were well separated from the analyte peak.
Determination of ambroxol hydrochloride using dithiocarbamic acid colorimetric method
Pai PNS,Lalitha N,Balakrishna B,Rao G
Indian Journal of Pharmaceutical Sciences , 2006,
Abstract: A new simple, colorimetric method was developed on the basis of a chemical reaction of amine group in ambroxol hydrochloride with carbon disulphide to form dithiocarbamic acid, which on further reaction with cupric chloride forms a colored copper chelate. The yellowish-orange chromophore has absorption maxima of 448 nm and obeys Beer′s law in the concentration range of 10-100 μg/ml. Results of the analysis were statistically validated by recovery studies. The method was found to be suitable for routine determination of ambroxol hydrochloride in tablet formulation.
DMT of Wireless Networks: An Overview (Invited Paper)
K. Vinodh,N. Prakash,V. Lalitha,P. Vijay Kumar
Journal of Communications , 2010, DOI: 10.4304/jcm.5.4.265-281
Abstract: The efficient operation of single-source, single-sink wireless networks is considered with the diversity-multiplexing gain tradeoff (DMT) as the measure of performance. Whereas in the case of a point-to-point MIMO channel the DMT is determined by the fading statistics, in the case of a network, the DMT is additionally, a function of the time schedule according to which the network is operated, as well as the protocol that dictates the mode of operation of the intermediate relays. In general, it is only possible at present, to provide upper bounds on the DMT of the network in terms of the DMT of the MIMO channel appearing across cuts in the network. This paper presents a tutorial overview on the DMT of half-duplex multi-hop wireless networks that also attempts to identify where possible, codes that achieve the DMT. For example, it is shown how one can construct codes that achieve the DMT of a network under a given schedule and either an amplify-and-forward or decode-andforward protocol. Also contained in the paper, are discussions on the DMT of the multiple-access channel as well as the impact of feedback on the DMT of a MIMO channel.
Staphylococcus aureus eye infections in two Indian hospitals: emergence of ST772 as a major clone
Nadig S,Velusamy N,Lalitha P,Kar S
Clinical Ophthalmology , 2012,
Abstract: Savitha Nadig1, Nithya Velusamy2, Prajna Lalitha2, Sarita Kar3, Savitri Sharma3, Gayathri Arakere11Society for Innovation and Development, Indian Institute of Science, Bengaluru, Karnataka, 2Aravind Eye Hospital, Madurai, Tamil Nadu, 3LV Prasad Eye Institute, Bhubaneswar, Odisha, IndiaPurpose: The purpose of this study was to perform molecular characterization of Staphylococcus aureus isolates causing a variety of eye infections from two major eye care hospitals in India.Methods: Twenty-four isolates from Aravind Eye Hospital, Madurai, India, and nine isolates from LV Prasad Eye Institute, Bhubaneswar, India, representing severe to nonsevere eye infections like microbial keratitis to lacrimal sac abscess, were characterized. Staphylococcal cassette chromosome mec typing, multilocus sequence typing, accessory gene regulator typing, staphylococcal protein A typing, and pulsed field gel electrophoresis were used, along with determination of the presence of Panton–Valentine leucocidin toxin and endotoxin gene cluster among each sequence type.Results: The majority of eye infections, both severe and nonsevere, were caused by sequence type (ST)772, positive for the Panton–Valentine leucocidin gene, and carrying methicillin-resistant staphylococcal cassette chromosome mec type V cassette (22/33, 67%). Some of the other sequence types that caused severe eye infections were ST1 (9%), 5 (3%), 72 (6%), 88 (3%), 121 (3%), and 672 (3%). This is the first report of the presence of ST1 and 88 in India.Conclusion: Although the number of isolates included in this study was small, most of the eye infections were caused by community-associated S. aureus where patients had no history of hospitalization or treatment in the past year. In the case of six severe infections, patients were admitted for surgeries and there is probability of hospital infection. In addition, only methicillin-resistant S. aureus isolates carrying staphylococcal cassette chromosome mec type V were detected. Epidemic methicillin-resistant Staphylococcus aureus 15 (ST22) is a major ST found in health care as well as community settings in non-eye infections in India, but only one methicillin-sensitive S. aureus isolate belonging to ST22 was detected. Predominantly ST772, along with a few other STs, caused the 33 eye infections studied.Keywords: CA-MRSA, severe and nonsevere eye infections, ST772, PVL, agr type II
Codes with Local Regeneration
Govinda M. Kamath,N. Prakash,V. Lalitha,P. Vijay Kumar
Mathematics , 2012,
Abstract: Regenerating codes and codes with locality are two schemes that have recently been proposed to ensure data collection and reliability in a distributed storage network. In a situation where one is attempting to repair a failed node, regenerating codes seek to minimize the amount of data downloaded for node repair, while codes with locality attempt to minimize the number of helper nodes accessed. In this paper, we provide several constructions for a class of vector codes with locality in which the local codes are regenerating codes, that enjoy both advantages. We derive an upper bound on the minimum distance of this class of codes and show that the proposed constructions achieve this bound. The constructions include both the cases where the local regenerating codes correspond to the MSR as well as the MBR point on the storage-repair-bandwidth tradeoff curve of regenerating codes. Also included is a performance comparison of various code constructions for fixed block length and minimum distance.
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