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Search Results: 1 - 10 of 126973 matches for " LI Zhonghao "
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Cellulose/Gold Nanocrystal Hybrids via an Ionic Liquid/Aqueous Precipitation Route
Zhonghao Li,Andreas Taubert
Molecules , 2009, DOI: 10.3390/molecules14114682
Abstract: Injection of a mixture of HAuCl4 and cellulose dissolved in the ionic liquid (IL) 1-butyl-3-methylimidazolium chloride [Bmim]Cl into aqueous NaBH4 leads to colloidal gold nanoparticle/cellulose hybrid precipitates. This process is a model example for a very simple and generic approach towards (noble) metal/cellulose hybrids, which could find applications in sensing, sterile filtration, or as biomaterials.
Lessons from a “Failed” Experiment: Zinc Silicates with Complex Morphology by Reaction of Zinc Acetate, the Ionic Liquid Precursor (ILP) Tetrabutylammonium Hydroxide (TBAH), and Glass
Zhonghao Li,Yaroslav Z. Khimyak,Andreas Taubert
Materials , 2008, DOI: 10.3390/ma1010003
Abstract: At elevated temperatures, the ionic liquid precursor (ILP) tetrabutylammonium hydroxide reacts with zinc acetate and the glass wall of the reaction vessel. While the reaction of OH- with the glass wall is not surprising as such and could be considered a failed experiment, the resulting materials are interesting for a variety of applications. If done on purpose and under controlled conditions, the reaction with the glass wall results in uniform, well-defined hemimorphite Zn4Si2O7(OH)2·nH2O and willemite Zn2SiO4 microcrystals and films. Their morphology can be adjusted by variation of the reaction time and reaction temperature. The hemimorphite can be transformed to Zn2SiO4 via calcination. The process is therefore a viable approach for the fabrication of porous films on glass surfaces with potential applications as catalyst support, among others.
CHSMiner: a GUI tool to identify chromosomal homologous segments
Zhen Wang, Guohui Ding, Zhonghao Yu, Lei Liu, Yixue Li
Algorithms for Molecular Biology , 2009, DOI: 10.1186/1748-7188-4-2
Abstract: Here we present a Java software CHSMiner that detects CHSs based on shared gene content alone. It implements fast greedy search algorithm and rigorous statistical validation, and its friendly graphical interface allows interactive visualization of the results. We tested the software on both simulated and biological realistic data and compared its performance with similar existing software and data source.CHSMiner is characterized by its integrated workflow, fast speed and convenient usage. It will be useful for both experimentalists and bioinformaticians interested in the structure and evolution of genomes.The identification of chromosomal homologous segments (CHSs) within and between genomes (known as paralogons and syntenies, respectively) is essential for comparative genomics. It can not only help evolutionary biologists to study genome evolution, such as genome duplication and rearrangement [1,2], but also help experimental biologists to transfer gene function information from one genome to another. Although extensive gene mutation, deletion, and insertion have made them not always obvious from primary sequences, chromosomal homology can still be revealed by a pair of segments sharing a group of homologous genes [3]. Most existing programs, including ADHoRe [4], FISH [5] and LineUp [6], look for CHSs based on the conservation of both gene content and order (colinearity). While the approach was sensitive enough for moderate divergence, it has been pointed out conserved gene order may be too strict for more ancient divergence [3], as inversion is another dominant force for the degeneration of CHSs. For example, the whole genome duplication in early vertebrate evolution can only be inferred by discarding gene order and considering gene content alone [7]. A pioneering implementation of this strategy was CloseUp [8], but some limitations still exist, especially with the rapid increase of genomic data. First, it used Monte Carlo simulation to estimate the statistical
JIN Man,JIANG Zhonghao,NAN Shenghui,HU Jiandong,LIAN jiansheCorrespondent:LI Geping,

金属学报(英文版) , 1995,
Tree of Life Based on Genome Context Networks
Guohui Ding, Zhonghao Yu, Jing Zhao, Zhen Wang, Yun Li, Xiaobin Xing, Chuan Wang, Lei Liu, Yixue Li
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0003357
Abstract: Efforts in phylogenomics have greatly improved our understanding of the backbone tree of life. However, due to the systematic error in sequence data, a sequence-based phylogenomic approach leads to well-resolved but statistically significant incongruence. Thus, independent test of current phylogenetic knowledge is required. Here, we have devised a distance-based strategy to reconstruct a highly resolved backbone tree of life, on the basis of the genome context networks of 195 fully sequenced representative species. Along with strongly supporting the monophylies of three superkingdoms and most taxonomic sub-divisions, the derived tree also suggests some intriguing results, such as high G+C gram positive origin of Bacteria, classification of Symbiobacterium thermophilum and Alcanivorax borkumensis in Firmicutes. Furthermore, simulation analyses indicate that addition of more gene relationships with high accuracy can greatly improve the resolution of the phylogenetic tree. Our results demonstrate the feasibility of the reconstruction of highly resolved phylogenetic tree with extensible gene networks across all three domains of life. This strategy also implies that the relationships between the genes (gene network) can define what kind of species it is.
Detection of Massive Numbers of Dvds by a UHF RFID System
Zhonghao Hu;Peter Cole
PIER B , 2011, DOI: 10.2528/PIERB10072206
Abstract: This paper aims to provide an effective solution to the problem of detecting a large number of densely stacked DVDs. The number is in the range of 2000. In order to achieve that goal, firstly the structure and the properties of materials comprising a DVD disc and a DVD case are investigated. The effect of the metal layer in the disc on the interrogating wave is evaluated via theoretical analysis and simulation. Based on that analysis and simulation, and on numerous experiments on either a single labeled DVD in free space or multiple labeled DVD in a DVD stack, two solutions are proposed whereby over 95% DVDs in a great portion of a 2000 DVD stack could be detected. Eliminating the tags which have weak performance, the percentage can be 100%. This paper not only expands the range of categories detectable by UHF RFID systems but also provides a process and method for item-level tagging in which the number of the items is in the range of thousands.
Photocatalytic Degradation of Oxalic Acid by TiO_2/Graphene Composite

朱冬韵, 廖高祖, 唐仲豪, 李来胜
Zhu Dongyun
, Liao Gaozu, Tang Zhonghao, Li Laisheng

- , 2015, DOI: 10.6054/j.jscnun.2014.12.020
Abstract: 以钛酸四丁酯和氧化石墨烯为原料,采用水热法制备了二氧化钛/石墨烯(TiO_2/RGO)复合光催化剂,用XRD、TEM、UVVis DRS对光催化剂进行了表征. 研究了其在紫外光和模拟太阳光条件下对草酸的光催化降解性能,结果表明,与TiO_2相比,TiO_2/RGO在紫外光条件下,反应10 min后对草酸的光催化降解率增加了2.97%,这主要是因为石墨烯为TiO_2提供了电子转移场所,提高了电子-空穴的分离效率;而在模拟太阳光条件下,反应10 min后TiO_2/RGO对草酸的光催化降解率增加了9.05
: A TiO_2/Graphene (TiO_2/RGO) composite was synthesized by a hydrothermal method using graphite oxide and tetrabutyl. The crystal phase and morphology were characterized by Xray diffraction, transmission electron microscope, and UVVis diffuse reflecta
Exact Solutions for Extended Higher-order Nonlinear Schrdinger Equation Including Raman Self-frequency Shift

Tian Huiping,TIAN JinPing,LI Zhonghao,Zhou Guosheng,

光子学报 , 2003,
Abstract: An extended higher-order nonlinear Schr dinger equation including the self-frequency shift effect caused by Raman gain is solved. This equation is used to describe the propagation of subpicosecond and femtosecond optical pulses in fibers. To get exact solutions, nonlinear gain and nonresonant effect are considered. As a result, the exact bright and dark solitary wave solutions are obtained. Moreover, it is pointed out that the bright solitary wave exists in negative third-order dispersion regime and the dark solitary wave exists in positive third-order dispersion regime.
Stochastic Optimization Theory of Backward Stochastic Differential Equations Driven by G-Brownian Motion
Zhonghao Zheng,Xiuchun Bi,Shuguang Zhang
Mathematics , 2013,
Abstract: In this paper, we consider the stochastic optimal control problems under G-expectation. Based on the theory of backward stochastic differential equations driven by G-Brownian motion, which was introduced in [10.11], we can investigate the more general stochastic optimal control problems under G-expectation than that were constructed in [28]. Then we obtain a generalized dynamic programming principle and the value function is proved to be a viscosity solution of a fully nonlinear second-order partial differential equation.
Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance
Katsuya Tanabe,Zhonghao Liu,Satish Patel,Bradley W. Doble,Lin Li,Corentin Cras-Méneur,Sara C. Martinez,Cris M. Welling,Morris F. White,Ernesto Bernal-Mizrachi,James R. Woodgett,M. Alan Permutt
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0060037
Abstract: Despite treatment with agents that enhance β-cell function and insulin action, reduction in β-cell mass is relentless in patients with insulin resistance and type 2 diabetes mellitus. Insulin resistance is characterized by impaired signaling through the insulin/insulin receptor/insulin receptor substrate/PI-3K/Akt pathway, leading to elevation of negatively regulated substrates such as glycogen synthase kinase-3β (Gsk-3β). When elevated, this enzyme has antiproliferative and proapoptotic properties. In these studies, we designed experiments to determine the contribution of Gsk-3β to regulation of β-cell mass in two mouse models of insulin resistance. Mice lacking one allele of the insulin receptor (Ir+/?) exhibit insulin resistance and a doubling of β-cell mass. Crossing these mice with those having haploinsufficiency for Gsk-3β (Gsk-3β+/?) reduced insulin resistance by augmenting whole-body glucose disposal, and significantly reduced β-cell mass. In the second model, mice missing two alleles of the insulin receptor substrate 2 (Irs2?/?), like the Ir+/? mice, are insulin resistant, but develop profound β-cell loss, resulting in early diabetes. We found that islets from these mice had a 4-fold elevation of Gsk-3β activity associated with a marked reduction of β-cell proliferation and increased apoptosis. Irs2?/? mice crossed with Gsk-3β+/? mice preserved β-cell mass by reversing the negative effects on proliferation and apoptosis, preventing onset of diabetes. Previous studies had shown that islets of Irs2?/? mice had increased cyclin-dependent kinase inhibitor p27kip1 that was limiting for β-cell replication, and reduced Pdx1 levels associated with increased cell death. Preservation of β-cell mass in Gsk-3β+/?Irs2?/? mice was accompanied by suppressed p27kip1 levels and increased Pdx1 levels. To separate peripheral versus β-cell–specific effects of reduction of Gsk3β activity on preservation of β-cell mass, mice homozygous for a floxed Gsk-3β allele (Gsk-3F/F) were then crossed with rat insulin promoter-Cre (RIP-Cre) mice to produce β-cell–specific knockout of Gsk-3β (βGsk-3β?/?). Like Gsk-3β+/? mice, βGsk-3β?/? mice also prevented the diabetes of the Irs2?/? mice. The results of these studies now define a new, negatively regulated substrate of the insulin signaling pathway specifically within β-cells that when elevated, can impair replication and increase apoptosis, resulting in loss of β-cells and diabetes. These results thus form the rationale for developing agents to inhibit this enzyme in obese insulin-resistant individuals to preserve β-cells and prevent diabetes onset.
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