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Search Results: 1 - 10 of 149873 matches for " LI You-ming "
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Recurrent achalasia treated with Heller myotomy: A review of the literature
Lan Wang, You-Ming Li
World Journal of Gastroenterology , 2008,
Abstract: AIM: To evaluate the efficacy and safety of Heller myotomy (HM) for recurrent achalasia, performed after different methods of first-line treatment.METHODS: We searched for studies published in PubMed from 1966 to March 2008 on treatment of recurrent achalasia with HM after failure with different methods of first-line treatment. The efficacy of HM was assessed by a pooled estimate of response rate with individual studies weighted proportionally to sample size.RESULTS: Sixteen studies were eligible and included in the review. The results showed that HM has a better remission rate for recurrent achalasia after failure of HM [weighted mean (SD)] of 86.9% (21.8%) compared with 81.6% (23.8%) for pneumatic dilatation (PD). One study evaluated the efficacy of HM after failure of PD combined with botulinum toxin injection (83%). The most common complications were perforation and gastroesophageal reflux.CONCLUSION: HM has the best efficacy in patients with recurrent achalasia who were treated with HM as first-line treatment. Future studies should focus on how to increase the success rate and decrease the complications of HM.
The commemoration of professor Li Shixiong

LI You-ming,

地球物理学进展 , 2007,
Abstract: In this paper,the author presents professor Li Shixiong's contribution on seismic imaging,Wavelet,Independent Component Analysis(ICA) and academic study on dynamic problem under complex condition based on the realization of professor Ii Shixiong's study on oil and gas exploration,at the same time expresses the deeply respect for professor Li's spirit on exalting the judgment of young scientist and instruction on improving the production of team research.
The Outline and General Comments about the Advance of the Resevoir Geophysics Project Implemented in Daqing Oilfield

LI You-ming,

地球物理学进展 , 2006,
Abstract: Shortly after the constitution of this project,in order to verify the feasibility of the theoretical research implementation,we proposed an additional requirement of direct involving in the production of oil and gas reservoirs in the outer part and deep part of Daqing,so that the overall merit of both theoretical research and practical application of this project can be improved.With the successful construction of PC-clusters and development of the seismic data parallel processing system plus assistant software packages in 1998,we built up the 3D wave equation pre-stack depth migration algorithm and the corresponding software in 2000,which is synchronous with international seismic exploration community.Such an achievement greatly improves the capability of seismic imaging in China.In the year of 1999,we assembled an eight-node PC-cluster and processed 150 km-long seismic profiles.In paticular,on the depth map of line 82,we clearly imaged the internal structure and fault character of an uplift in a depression area.After a rearrangement of 3D seismic exploration and with many research works,a great break through was achieved accomanying the drilling of the Xushen No.1 well and leading to the discovery of the huge gas field in Daqing.This success remarkably improves the continuable development foreground of Daqing oilfield.We have also built up two reservoir geophysics research centers in Beijing and Daqing,respectively.It has been proved that proper and reasonable research organization and activity will benefit the integration and application of the products of a great scientific project,and is key to make progress with combined efforts consecutively and efficiently.
Gene therapy: Regulations, ethics and its practicalities in liver disease
Xi Jin, Yi-Da Yang, You-Ming Li
World Journal of Gastroenterology , 2008,
Abstract: Gene therapy is a new and promising approach which opens a new door to the treatment of human diseases. By direct transfer of genetic materials to the target cells, it could exert functions on the level of genes and molecules. It is hoped to be widely used in the treatment of liver disease, especially hepatic tumors by using different vectors encoding the aim gene for anti-tumor activity by activating primary and adaptive immunity, inhibiting oncogene and angiogenesis. Despite the huge curative potential shown in animal models and some pilot clinical trials, gene therapy has been under fierce discussion since its birth in academia and the public domain because of its unexpected side effects and ethical problems. There are other challenges arising from the technique itself like vector design, administration route test and standard protocol exploration. How well we respond will decide the fate of gene therapy clinical medical practice.
A systematic review and meta-analysis of the Chinese literature for the treatment of achalasia
Lan Wang, You-Ming Li, Lan Li, Chao-Hui Yu
World Journal of Gastroenterology , 2008,
Abstract: AIM: To evaluate the effect of different approaches in the treatment of achalasia in China.METHODS: We performed a systematic review and meta-analysis of Chinese literature by searching the Chinese Biomedical Database and Chinese scientific Journals database (up to March 2008). All cohort studies (controlled or uncontrolled) in which the patients were observed for more than a year were reviewed in detail. Dichotomous outcomes were reported as relative risks (RR) with 95% confidence interval (CI) for controlled trials. The efficacy in uncontrolled trials was assessed by a pooled estimate of response rate with individual studies weighted in proportion to the sample size.RESULTS: Seven controlled trials compared the effect of botulinum toxin injection (BoTx) with pneumatic dilation (PD). PD was superior to BoTx [65.2% vs 45.3%; RR 1.47 (95% CI 1.23-1.77), P < 0.0001], and had a lower clinical relapse rate (BoTx 30.2% vs PD 10%, RR 0.32 (0.16-0.65), P = 0.001). Heller myotomy (HM) had superior remission rate compared to PD [HM 94.0% vs PD 64.1%, RR 1.48 (1.15-1.99), P = 0.002]. In uncontrolled trials, the effectiveness of PD was 86.6% (23.9%) vs 94.8% (10.6%) for HM. The main complications of PD were perforation and gastroesophageal reflux disease.CONCLUSION: HM is the most effective long-term treatment for patients with achalasia in China. In the future, controlled clinical trials on the treatment of achalasia should focus on comparing laparoscopic myotomy with or without antireflux procedure, including different partial and total fundoplication techniques.
Early mortality of alcoholic hepatitis: A review of data from placebo-controlled clinical trials
Chao-Hui Yu, Cheng-Fu Xu, Hua Ye, Lan Li, You-Ming Li
World Journal of Gastroenterology , 2010,
Abstract: AIM: To investigate the early mortality of placebo-treated alcoholic hepatitis patients.METHODS: Mortality data about alcoholic hepatitis patients who participated in randomized placebo-controlled trials were searched from PubMed, EMBASE, and Cochrane Library, extracted and analyzed.RESULTS: A total of 661 placebo-treated patients in 19 trials were included. The overall mortality rate was 34.19% with a median observation time of 160 d (range 21-720 d). Hepatic failure, gastrointestinal bleeding and infection were the three main causes of death, accounting for 55.47%, 21.17% and 7.30% of all deaths, respectively. One-month mortality data about 324 placebo-treated alcoholic hepatitis patients in 10 trials were reported with a pooled mortality rate of 20.37%. The one-month mortality rate of patients with moderate to severe alcoholic hepatitis tended to be higher than that of general patients (22.69% vs 10.93%, P < 0.05), whereas no significant difference was observed between the patients from North America or Europe (22.43% vs 18.45%, P > 0.05), neither any difference was found between the studies published before and after 1990 (18.18% vs 21.88%, P > 0.05).CONCLUSION: Alcoholic hepatitis is a severe liver disease with a high mortality rate, and hepatic failure, gastrointestinal bleeding and infection are the three main causes of death.
A Geometric Rectification Algorithm of Scanned Topographic Map Based on Hough Transform
基于Hough 变换的扫描地形图几何纠正算法研究

LI Guan-yi,LIN You-ming,

遥感技术与应用 , 2006,
Abstract: 扫描的地形图存在一定的误差,可采用方里网精纠正方法对其进行几何纠正。这需要大量的控制点,一般采用图中方里网格线交点作为控制点。针对地形图网格点的提取,对Hough变换进行了改进,即采取预测网格点的方法确定搜索区域,用Hough变换提取方里网格点,然后把所有检测出的方里网格点组成三角网格,用仿射变换对地形图进行分三角网格精纠正。实验表明,该方法检测精度高,只需要少量的人工干预,即可实现所有网格点的子像元级提取。
Bis({1-[(1-iminoethyl)imino]ethyl}azanido-κ2N1,N5)nickel(II) methanol monosolvate
Yong-Qiang Xie,Jun-Jian Li,Ying Guo,You-Ming Zhang
Acta Crystallographica Section E , 2013, DOI: 10.1107/s1600536812046958
Abstract: The title compound, [Ni(C4H8N3)2]·CH3OH, contains two independent NiII atoms, each located on an inversion center and coordinated by four N atoms from two 1-[(1-iminoethyl)imino]ethyl}azanide ligands in a square-planar geometry. N—H...N, N—H...O and O—H...N hydrogen bonds link the complex molecules and methanol solvent molecules into a corrugated layer parallel to (001).
Single-center experience of 309 consecutive patients with obscure gastrointestinal bleeding
Bing-Ling Zhang, You-Hong Fang, Chun-Xiao Chen, You-Ming Li, Zun Xiang
World Journal of Gastroenterology , 2009,
Abstract: AIM: To investigate the diagnostic yield of capsule endoscopy (CE) in patients with obscure gastrointestinal bleeding (OGIB), and to determine whether the yield was affected by different bleeding status.METHODS: Three hundred and nine consecutive patients (all with recent negative gastric and colonic endoscopy results) were investigated with CE; 49 cases with massive bleeding and 260 cases with chronic recurrent overt bleeding. Data regarding OGIB were obtained by retrospective chart review and review of an internal database of CE findings.RESULTS: Visualization of the entire small intestine was achieved in 81.88% (253/309) of cases. Clinically positive findings occurred in 53.72% (166/309) of cases. The positivity of the massive bleeding group was slightly higher than that of the chronic recurrent overt bleeding group but there was no significant difference (59.18% vs 52.69%, P > 0.05) between the two groups. Small intestinal tumors were the most common finding in the entire cohort, these accounted for 30% of clinically significant lesions. In the chronic recurrent overt bleeding group angioectasia incidence reached more than 29%, while in the massive bleeding group, small intestinal tumors were the most common finding at an incidence of over 51%. Increasing patient age was associated with positive diagnostic yield of CE and the findings of OGIB were different according to age range. Four cases were compromised due to the capsule remaining in the stomach during the entire test, and another patient underwent emergency surgery for massive bleeding. Therefore, the complication rate was 1.3%.CONCLUSION: In this study CE was proven to be a safe, comfortable, and effective procedure, with a high rate of accuracy for diagnosing OGIB.
Association between Hepatic Steatosis and Entecavir Treatment Failure in Chinese Patients with Chronic Hepatitis B
Xi Jin, Yi-peng Chen, Yi-da Yang, You-ming Li, Lin Zheng, Chuan-qing Xu
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0034198
Abstract: Background The coexistence of HBV infection and nonalcoholic fatty liver disease (NAFLD) becomes characteristic of liver disease in China, with unknown bilateral influence. We aimed to investigate the effect of hepatic steatosis, a common hepatocyte change in NAFLD, on antiviral therapy in patients with chronic hepatitis B (CHB). Methods and Findings We carried out a prospective nested case control study in CHB patients receiving Entecavir for initial antiviral therapy, by recording demographic, anthropometric and clinical data at baseline, 24wk, 48wk and 96wk. Univariate analysis and multivariate logistic regression were applied to find out independent factors of hepatic steatosis and Entecavir treatment failure. The rates of HBV-DNA clearance, HBeAg seroconversion and ALT normalization were compared between CHB patients with and without steatosis by post hoc analysis. A total of 267 Chinese patients with CHB entered final analysis, with overall percentages of hepatic steatosis and HBeAg positive as 30.5% and 62.4%. Multivariate analysis showed waist circumference, serum TG and uric acid levels were independent factors of hepatic steatosis. The response rates to Entecavir were 54.9%, 63.8%, 74.2% at 24wk, 48wk and 96wk. Hepatic steatosis was revealed as an independent factor of Entecavir treatment failure by multivariate logistic regression at 24wk, 48wk and 96wk. In CHB patients with hepatic steatosis, HBV-DNA clearance and HBeAg seroconversion were both lower throughout the follow-up, but only the former reached statistical significance. Besides, ALT normalization was also significantly lower at 24wk and 48wk. Conclusion Hepatic steatosis is significantly associated with Entecavir treatment failure and metabolic factors are independent factors of hepatic steatosis in CHB patients, which called for a specified antiviral strategy in CHB patients with NAFLD.
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