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Search Results: 1 - 10 of 149072 matches for " LI Ke-Jiang "
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Bradykinin β2 Receptor ?58T/C Gene Polymorphism and Essential Hypertension: A Meta-Analysis
Yan-yan Li, Hui Zhang, Jian Xu, Yun Qian, Xin-zheng Lu, Bing Yang, Minglong Chen, Zhi-jian Yang, Ke-jiang Cao
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0043068
Abstract: Background Research has shown that bradykinin β2 receptor (BDKRB2) ?58T/C gene polymorphism is correlated with the risk of essential hypertension (EH), but the results remain inconclusive. Objective and Methods The objective of this study was to explore the association between BDKRB2?58T/C gene polymorphism and EH. A meta-analysis of 11 studies with 3882 subjects was conducted. Pooled odds ratios (ORs) for the association between BDKRB2?58T/C gene polymorphism and EH and their corresponding 95% confidence intervals (CIs) were estimated using the random effects model. Results The BDKRB2?58T/C gene polymorphism was significantly correlated with EH under an allelic genetic model (OR = 1.24, 95% CI = 1.05–1.46; P = 0.01), a dominant genetic model (OR = 0.65, 95% CI = 0.47–0.90; P = 0.01), a recessive genetic model (OR = 1.146, 95% CI = 1.035–1.269; P = 0.009), a homozygote genetic model (OR = 1.134, 95% CI = 1.048–1.228; P = 0.002), and a heterozygote genetic model (OR = 1.060, 95% CI = 1.009–1.112; P = 0.019). Conclusions The BDKRB2?58T/C gene polymorphism is associated with increased EH risk. The results of this study suggest that carriers of the ?58C allele are susceptible to EH.
Monitoring and evaluation of sewage quality in Heilonggang Region
黑龙港蓄污区污水水质监测与评价研究

LI Ke-Jiang,CAO Cai-Yun,ZHENG Chun-Lian,WANG You-Zeng,
李科江
,曹彩云,郑春莲,王有增

中国生态农业学报 , 2005,
Abstract: 运用单项指数和综合指数相结合方法,对黑龙港蓄污区污水水质监测与评价结果表明,该水体为严重污染水体,且重金属为最主要污染因子,其中Pb、Cd和Hg超标量高达3~23倍。根据国家农业灌溉水质标准,该水体不宜用于农业灌溉。
STUDIES ON ULTRASONIC DEGRADATION AND BLOCK COPOLYMERIZATION OF HYDROXYETHYL CELLULOSE AND POLY(ETHYLENE OXIDE)
羟乙基纤维素和聚氧化乙烯在超声波辐照下的降解与嵌段共聚的研究

CHEN Ke-jiang,SHEN Ye,LI Hui-lin,XU Xi,
陈克强
,沈埜,李惠林,徐僖

高分子学报 , 1985,
Abstract: 本文分别研究了在超声波辐照下羟乙基纤维素(HEC)和聚氧化乙烯(PEO)在水溶液中的降解规律,HEC与PEO在水溶液中的超声波辐照共聚反应。用DTA、IR、MS、X射线衍射和偏光显微镜初步研究了共聚物的结构,证明所得产物主要是嵌段共聚物。将浓度为0.5%的HEC/PEO水溶液在25±1℃,频率为18.2kHz,超声波强度(以逆变器主迴路输入电流表示)为2.5A下辐照10分钟,共聚物产率为55.07%。
Association of SNP Rs6903956 on Chromosome 6p24.1 with Angiographical Characteristics of Coronary Atherosclerosis in a Chinese Population
Chang-Yan Guo, Yan Gu, Li Li, En-Zhi Jia, Chun-Jian Li, Lian-Sheng Wang, Zhi-Jian Yang, Ke-Jiang Cao, Wen-Zhu Ma
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0043732
Abstract: Objective To explore the association between rs6903956 and severity of coronary artery disease (CAD) in a Chinese population. Methods A cohort of 1075 consecutive patients who underwent coronary arteriography for suspected or known coronary atherosclerosis was enrolled in our study. Coronary atherosclerosis severity was defined by Gensini's Score System and counts of diseased vessels. Results Gensini score frequencies and counts of diseased vessels differed among GG, AG, AA genotype groups at the rs6903956 locus (p = 0.025 for Gensini score frequencies vs. p = 0.024 for counts of diseased vessels, respectively). A univariate logistic regression analysis revealed that the genotype distribution of this SNP was associated significantly with angiographical characteristics of coronary atherosclerosis risk (p = 0.030, odds ratio (OR) = 1.444, 95% confidence interval (CI) = 1.036~2.013 for AG vs. GG; p = 0.021, OR = 5.896, 95% CI = 1.299~26.750 for AA vs. GG and p = 0.007, OR = 1.564, 95% CI = 1.132~2.162 for combined (AG+AA) vs. GG). A multivariate logistic regression analysis indicated that the genotype distribution of the rs6903956 polymorphism be associated significantly with the angiographical characteristics of coronary atherosclerosis risk (p = 0.004, OR = 1.578, 95% CI = 1.155~2.154 for GG vs. AG vs. AA; p = 0.013, OR = 1.541, 95% CI = 1.097~2.163 for GG vs. GA+ AA). A stratification analysis revealed that male subjects and smoking subjects had a higher frequency of the rs6903956 heterozygous mutant among higher Gensini score subjects than among lower Gensini score subjects (p = 0.023, OR = 1.579, 95% CI = 1.064~2.344 for male subgroup; p = 0.005, OR = 2.075, 95% CI = 1.249~3.448 for smoking subgroup). Conclusions Allele A is a risk factor for CAD and the G-to-A allele substitution may underlie the association between rs6903956 and CAD.
Time Distribution of the Onset of Chest Pain in Subjects with Acute ST-Elevation Myocardial Infarction: An Eight-Year, Single-Center Study in China
En-Zhi Jia, Zhen-Xia Xu, Hong-Zhou Cai, Chang–Yan Guo, Li Li, Tie-Bing Zhu, Lian-Sheng Wang, Ke-Jiang Cao, Wen-Zhu Ma, Zhi-Jian Yang
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0032478
Abstract: Objective The objective of this study was to explore the time distribution patterns of the onset of chest pain in subjects with acute ST-elevation myocardial infarction in a Chinese population. Methods A total of 1467 patients with acute ST-elevation myocardial infarction were enrolled from 2003 to 2010. The hourly, daily, monthly, seasonal and day-of-week fluctuations in the prevalence of acute ST-elevation myocardial infarction were analyzed. Results A peak was found between the morning hours of 07:31 and 08:30. A second peak was observed between 14:31 and 15:30, and a third peak was found between 23:31 and 00:30 (p<0.001). The monthly maximum was recorded in November and the minimum was in April (p<0.001). The number of daily cases was greatest in autumn and lowest in the spring (p = 0.001). Day-of-the-week variations of ST-elevation acute myocardial infarction were not found, except in patients more than 75-years-old. Conclusions Periodic variations in the frequency of ST-elevation acute myocardial infarction in Chinese patients showed significant differences with regard to diurnal, monthly and seasonal patterns. The exact mechanisms underlying these circadian variations require further study.
Impact of saline water irrigation with different salinities on yield and physiological indices of wheat
不同矿化度咸水灌溉对小麦产量和生理特性的影响

CAO Cai-Yun,ZHENG Chun-Lian,LI Ke-Jiang,DANG Hong-Kai,LI Wei,MA Jun-Yong,
曹彩云
,郑春莲,李科江,党红凯,李 伟,马俊永

中国生态农业学报 , 2013,
Abstract: To make full use of salt water resources in minimizing the severity of scarcity of fresh water resources in the Low Hebei Plain, the impacts of salt water irrigation on wheat yield and selected leaf physiological indices were analyzed. The indices included relative electrical conductivity, MDA (malondialdehyde) content, Pro (proline) content, and concentrations of K+, Ca2+ and Na+, as well as K+/Na+ ratio. And their relationships with salt tolerance of wheat varieties were discussed too. The analysis was based on data from a long-term field trial of salt water irrigation. In the trial, the split-plot design was used with irrigation water salinity as main plots and wheat variety the sub-plots. The results showed that cell membrane permeability, MDA content, Pro content and Na+ concentration increased in leaves with increasing salinity of irrigation water. However, K+/Na+ ratio and Ca2+ concentration declined for increasing salinity treatments. Based on yield and salt tolerance index analysis, the "Shijiazhuang 8" variety was more salt-tolerant than "Heng 4399". For the physiological indices, "Shijiazhuang 8" cell membrane was more stable than "Heng 4399" cell membrane. For "Heng 4399", membrane permeability increased sharply at a irrigation water salinity of 2 g·L-1. Sharp increase in membrane permeability of "Shijiazhuang 8" was only noted at a irrigation water salinity of 4 g·L-. In comparison with "Heng 4399", salt tolerance characteristics of "Shijiazhuang 8" were related to its ability to maintain higher levels of K+ and K+/Na+ and lower levels of Pro, however, it was less related with Na+ and Ca2+ concentrations. For MDA level, "Shijiazhuang 8" was lower during reviving and booting periods compared with "Heng 4399", but higher during heading and milking periods. Yields of both "Shijiazhuang 8" and "Heng 4399" decreased significantly when irrigation water salinity was above 4 g·L-1, but the decrease was always less in "Shijiazhuang 8" than in "Heng 4399" under similar treatments. With the continuous use of saline water irrigation, it was necessary to keep irrigation water salinity under 4 g·L-1. Also choosing salt tolerant varieties was very critical for high harvest in the Low Hebei Plain.
Effect of long-term fertilization on photosynthetic property and yield of summer maize (Zea mays L.)
长期定位施肥对夏玉米光合特性及产量的影响研究

CAO Cai-Yun,ZHENG Chun-Lian,LI Ke-Jiang,MA Jun-Yong,CUI Yan-Hong,
曹彩云
,郑春莲,李科江,马俊永,崔彦宏

中国生态农业学报 , 2009,
Abstract: Based on a long-term fertilization split design experimentation, the effect of combined chemical fertilizer and straw application on photosynthetic property and yield of summer maize was determined. The main treatment in the study was chemical fertilization, and maize-straw fertilization was the sub-treatment. The variables investigated include leaf area, leaf area index and chlorophyll content. The results indicate that though long-term maize-straw application positively influences maize yield, a large-scale yield increase mainly relies on chemical fertilization. Yield for the combined application of maize-straw and chemical fertilizer is much higher than that for individual applications of the fertilizers. The indices for photosynthesis, leaf area, leaf area index increase with increasing application of chemical fertilizer, and the leaf area index keeps around 3.5 at the late filling stage. Long-term application of maize-straw increases leaf area and grain number hence yields. In comparison with chemical fertilizer, maize-straw application only or no fertilization decrease the chlorophyll content. The combination of maize-straw and chemical fertilizer further increases grain number and 1000-grain weight, delays leaf decrepitude and prolongs leaf functional period, eventually increases summer maize yield. Combined application of chemical fertilizer and crop straw is a better fertilization mode for high summer maize yield in the study area.
Effects of winter drought resistant strategies on wheat water consumption and growth characteristics
冬季抗旱措施对小麦耗水特征与生育性状的影响

DANG Hong-Kai,ZHENG Chun-Lian,MA Jun-Yong,CAO Cai-Yun,WANG Gui-Feng,LI Wei,LI Ke-Jiang,
党红凯
,郑春莲,马俊永,曹彩云,王桂锋,李 伟,李科江

中国生态农业学报 , 2012,
Abstract: Water resource deficiency is one of major limitations to winter wheat production in Hebei Lowland Plain Areas. Drought resistant strategies are critical for high yield and quality wheat grain production. The effects of drought resistant measures (sprinkler irrigation at winter plus 75 mm irrigation at revival stage, flood irrigation at winter plus 75 mm irrigation at revival stage, and cattle manure mulching at winter plus 90 mm irrigation at revival stage) with three treatment times in winter (Jan. 28, Feb. 12 and Feb. 27) on water consumption and growth characteristics of "Heng 4399" wheat cultivar was determined in this study under high-yield cultivation conditions in 2010-2011 growth season with 47.7 mm of precipitation. The results showed that total water consumption of wheat for the whole growth period was 384.93~464.24 mm. WUE (water use efficiency) was 15.23~20.87 kg·hm-2·mm-1. Periods with the highest water consumption were generally from double ridge to filling and then from sowing to wintering. At same treatments time, treatments with high irrigation amounts increased total water consumption while reducing irrigation WUE. Concurrent comparisons of different treatments showed that WUE under cattle manure mulching was higher than that under other drought resistant measures. Compared with flood irrigation, sprinkler irrigation saved more water and was also more suitable to wheat growth water needs. For the indices of soil water ratio, WUE and IWUE (irrigation water use efficiency), sprinkler irrigation was better than flood irrigation. For the same treatment at different times, there an increasing grain-yield trend was noted with delayed treatment. At a same time, the effects of different treatments on dry-matter accumulation and redistribution were different. Cattle manure mulching and CK treatments increased the relocation of dry-matter accumulated before anthesis to wheat grain. Flood and sprinkler irrigations increased dry-matter accumulation after anthesis and also dry-matter relocation ratio to grain. The above findings provided the theoretical basis for developing winter drought resistant strategies in winter wheat cultivation.
Effect of irrigation water salt content on cotton growth and yield
不同矿化度咸水造墒灌溉对棉花生长发育和产量的影响

LI Ke-Jiang,MA Jun-Yong,CAO Cai-Yun,ZHENG Chun-Lian,ZHANG Cang-Gen,NIU Ying-Jie,
李科江
,马俊永,曹彩云,郑春莲,张苍根,牛英洁

中国生态农业学报 , 2011,
Abstract: A split-plot design was adopted in an irrigation experiment before cotton sowing with irrigation water amount as the main treatment and water mineral salinity as sub-treatments. The experiment results showed that the rate of cotton emergence decreased with increased irrigation water salt content. The rate of cotton emergence was over 90% at 4 g·L-1 of irrigation water salinity. At 6 g·L-1 of irrigation water salinity, cotton emergence was 85%, but delayed. The optimum irrigation range was 22.5~34.0 mm. Inhibitory actions of water salt on cotton growth and development at early stage was more obvious than at late stage. There was no significant difference in cotton yield between the fresh water and salt water (<3.38 g·L-1) irrigation. At irrigation water salinity >3.38 g·L-1, cotton yield linearly dropped. Yield was, however, much higher at irrigation water salinity <8 g·L-1 than that under rainfed conditions.
N-acetylcysteine blocked hypoxia-reoxygenation induced apoptosis through ROS-p38 MAPK signaling pathway in neonatal rat cardiomyocytes

Feng-Xiang Zhang,Ming-Long Chen,Bing Yang,Ke-Jiang Cao,

老年心脏病学杂志(英文版) , 2009,
Abstract: Objective Previous investigations have shown that N-aeetylcysteine (NAC) could regulate diverse cell type's apoptosis. The purpose of this study was to evaluate the mechanism of NAC reversed apoptosis ofcardiomyocytes induced by hypoxia-reoxygenation (H/R). Methods Cardiomyocytes were treated with hypoxia 6 h and reoxygenation 72 h in the absence and presence of NAC (100 μmol/ L). The ROS was assayed by using Image-iTTM LIVE green reactive oxygen species detection kit. The viability of cell was assayed with trypan blue. Early stages ofapoptosis were assessed by flow cytometry using Annexin V, and late stages ofapoptosis were assessed using TUNEL system. Bcl2 and bax mRNA levels were determincd by real-time quantitative PCR. Bcl2, bax, p38 and pp38 protein levels were determined by western blot. Results We found that H/R could markedly increase ROS generation and induce the apoptosis of cardiomyocytes (P<0.01). NAC (100 p tool/L) significantly reduced the generation of ROS and apoptosis (P all <0.01). NAC also significantly reduced the protein ratio of pp38 and p38 and increased the RNA and protein ratio of bcl2 and bax (P all <0.01). Conclusion The results showed that NAC significantly reduced apoptosis through inhibiting the phosphorylation of p38 signal pathway, which has potential value for clinical cardiac diseases.
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