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Search Results: 1 - 10 of 341261 matches for " L.E.; Honrubia "
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Capacidad diagnóstica del GDx VCC para el diagnóstico del glaucoma
Borque,E.; Ferreras,A.; Polo,V.; Larrosa,J.M.; Pablo,L.E.; Honrubia,F.M.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2008, DOI: 10.4321/S0365-66912008000600005
Abstract: purpose: to assess the diagnostic ability of scanning laser polarimetry (gdx vcc) to differentiate between normal and glaucomatous eyes. methods: 417 eyes of 417 consecutive subjects were prospectively selected. they were classified into 60 healthy controls, 218 ocular hypertensive eyes, 68 glaucoma suspects, and 71 glaucomatous eyes, depending on intraocular pressure, optic nerve head morphology and standard automated perimetry results. all underwent a scanning laser polarimetry with the gdx vcc. retinal nerve fiber layer (rnfl) parameters of the gdx-vcc were compared among the four groups. receiver operating characteristic (roc) curves were plotted between normal and glaucomatous eyes. the best parameters were defined according to the area under the roc curve and the best sensitivity/specificity balance. results: most parameters of gdx-vcc exhibited differences between the glaucoma group and the rest of the groups. some parameters were also different between healthy patients and glaucoma suspects. the best parameter was the nerve fiber indicator (nfi; area under the roc curve: 0.876). nfi, superior normalized area, and inferior normalized area yielded the highest sensitivities at 85% and 90% fixed specificity. conclusions: most rnfl parameters measured with the gdx-vcc provided good diagnostic ability for open-angle glaucoma. the best gdx-vcc parameter in differentiating between normal and glaucomatous eyes was the nfi.
Relación entre la perimetría automatizada convencional y los parámetros de la capa de fibras nerviosas de la retina obtenidos con la polarimetría láser
López-Pe?a,M.J.; Ferreras,A.; Polo,V.; Larrosa,J.M.; Pablo,L.E.; Honrubia,F.M.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2010, DOI: 10.4321/S0365-66912010000100005
Abstract: purpose: to determine the relationship between the structural parameters of the retinal nerve fiber layer (rnfl) obtained by using the scanning laser polarimetry with variable corneal compensation (gdx vcc) and the results of standard automated perimetry (sap), in normal, ocular hypertensive, preperimetric glaucomas and glaucoma subjects. methods: a total of 423 eyes of 423 consecutive subjects were prospectively included in the study and classified depending on the basal intraocular pressure, optic nerve head appearance and sap results into four groups: 87 normal eyes, 192 ocular hypertensive eyes, 70 preperimetric glaucomas and 74 glaucomatous eyes. pearson′s correlation coefficients, between mean deviation (md), pattern standard deviation, number of points altered in each quadrant, and number of points altered at different probability levels of sap and structural parameters of rnfl obtained by using gdx vcc, were calculated in the different diagnostic groups. in the glaucoma group correlations between the 52 points tested by 24- 2 sita standard and gdx parameters were also calculated. regression curves were plotted for the strongest correlations. results: weak or non-significant correlations were found in the normal, ocular hypertensive and preperimetric glaucoma groups. however, the glaucoma group presented weak to moderate correlations between several gdx vcc parameters and the sap variables analysed. the strongest correlation was observed between the standard deviation tsnit and the md (0.460). conclusions: rnfl parameters measured with the gdx vcc presented weak to moderate correlations with the visual field indices and the number of altered points in the glaucoma group.
Efeito da adi??o de sulfito sobre a produ??o de alcoóis superiores durante a fermenta??o alcoólica
Gutierrez, L.E.;
Anais da Escola Superior de Agricultura Luiz de Queiroz , 1988, DOI: 10.1590/S0071-12761988000100022
Abstract: the effect of sulfited medium and its ph on the etanol, acetaldehyde and higher alcohols production during fermentation of cane molasse by saccharomyces cerevisiae was studied. there was no significant effect of sulfite on ethanol production. the results showed a significant increase in acetaldehyde and a reduction in higher alcohols content with the increase of sulfite concentration. the increase in the ph of sulfited medium caused an increase in acetaldehyde and higher alcohols content and did not affect ethanol production.
Efeito dos ácidos fórmico e propi?nico sobre a produ??o de alcoóis superiores durante a fermenta??o alcoólica
Gutierrez, L.E.;
Anais da Escola Superior de Agricultura Luiz de Queiroz , 1988, DOI: 10.1590/S0071-12761988000100023
Abstract: the effect of different concentrations of formic and propionic acids on the ethanol and higher alcohols production was studied with synthetic medium. there were no significant differences among ethanol , n-propilic, isobutilic and isoamilic alcohols in all treatments. however a reduction of isoamilic alcohol content was observed at higher levels of formic and propionic acids.
Acúmulo de trealose em linhagens de Saccharomyces durante fermenta??o alcoólica
Gutierrez, L.E.;
Anais da Escola Superior de Agricultura Luiz de Queiroz , 1990, DOI: 10.1590/S0071-12761990000200018
Abstract: this study was carried out to compare the effects of several factors (temperature, ph, sucrose concentration, 2,4-dinitrophenol and nitrogen sources) on trehalose production by saccharomyces uvarum iz-1904 and saccharomyces cerevisiae (m-300-a and baker's yeast) during alcoholic fermentation. trehalose production was lower with the yeast lz-1904 than with m-300-a or baker's yeast. more trehalose was formed at 34°c than at 25°c. for m-300-a and baker's yeast trehalose accumulation was higher at ph 4.5 than at ph 3.0. addition of 18ppm 2.4-dinitrophenol strongly decreased the amount of trehalose formed by baker's yeast, but was ineffective for iz-1904. increase of sucrose concentration led to a higher production of trehalose.
Efeito da adi??o de sulfato de am?nio sobre a produ??o de ácido succínico durante a fermenta??o alcoólica
Gutierrez, L.E.;
Anais da Escola Superior de Agricultura Luiz de Queiroz , 1988, DOI: 10.1590/S0071-12761988000100027
Abstract: succinic acid production by yeasts during alcoholic fermentation of cane molasse supplemented with 25, 50 and 100 ppm of nitrogen in the form of ammonium sulfate was determined by gas-liquid chromatography. ethanol production was not effected by the different levels of nitrogen, but there was a significant reduction in the content of succinic acid which was inversely related with the ammonium sulfate concentration in the medium.
Effect of some vitamins and micronutrient deficiencies on the production of higher alcohols by Saccharomyces cerevisiae
Gutierrez, L.E.;
Scientia Agricola , 1993, DOI: 10.1590/S0103-90161993000300024
Abstract: a study was carried out in order to determine the effect of vitamins (biotin, thiamine, pantotheniic acid and pyridoxal) and micronutrient (zinc, boron, manganese and iron) deficiencies on higher alcohol production during alcoholic fermentation with the industrially used yeast saccharomyces cerevisiae m-300-a. zinc deficiency induced a reduction on the levels of isobutyl and isoamyl alcohols. an increase on isobutyl alcohol (fivefold) and a reduction of isoamyl alcohol (two fold) and n-propyl alcohol (three fold) contents resulted from pantotheiiic acid deficiency, whereas pyridoxal deficiency caused an increase on the levels of isobutyl and isoamyl alcohols. biotin was not essential for the growth of this strain.
Changes in trehalose content of baker's yeast as affected by octanoic acid
Gutierrez, L.E.;
Scientia Agricola , 1993, DOI: 10.1590/S0103-90161993000300020
Abstract: octanoic acid inhibited ethanolic fermentation by saccharomyces cerevisiae (bakers yeast) and the trehalose accumulation, however did not affect the endogenous degradation of trehalose. this inhibition may be explained by the binding of octanoic acid to hexokinase or other proteins of plasma membrane because they are not necessary for endogenous fermentation. the degradation of trehalose may be due to an activation of trehalase.
Produ??o de álcoois superiores por linhagens de Saccharomyces durante a fermenta??o alcoólica
Gutierrez, L.E.;
Scientia Agricola , 1993, DOI: 10.1590/S0103-90161993000300021
Abstract: the production of higher alcohols by saccharomyces cerevisiae m-300-a, saccharomyces uvarum iz-1904 and baker's yeast (5. cerevisiae) was studied under several temperature conditions, sucrose level, ph, nitrogen sources and with 2-4 dinitrophenol (dnp). the yeast iz-1904 showed lower production of higher alcohols than other yeasts in all conditions studied. with the increase of temperature and higher level of sucrose an increase of isoamyl alcohol production was observed. a lower formation of higher alcohols was observed at ph 4.5 than at ph 3.0. with the addition of dnp occurred a significant reduction in isoamyl alcohol content. the yeasts did not show the sanie production of higher alcohols in relation to urea and ammonium sulfate.
Kayan phonemics.
L.E. Cubit
Bijdragen tot de Taal-, Land- en Volkenkunde , 1964,
Abstract:
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