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Search Results: 1 - 10 of 244005 matches for " L. Zhao "
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Sustainable approaches towards novel nitrogen-doped carbonaceous structures
L. Zhao
Boletin del Grupo Espa?ol del Carbon , 2012,
Abstract: This work will focus on novel carbonaceous materials which were produced in a sustainable fashion, using cheap starting precursors and uncomplicated synthetic approaches.
Architectural Features of Stilted Buildings of the Tujia People: A Case Study of Ancient Buildings in the Peng Family Village in Western Hubei Province, China  [PDF]
Kui Zhao, William L. Tilson, Dan Zhu
Journal of Building Construction and Planning Research (JBCPR) , 2013, DOI: 10.4236/jbcpr.2013.14014
Abstract: This paper describes and analyzes the stilted buildings of the Tujia people (an ethnic group living in mainland China), a distinctive building style unique to them, from the perspectives of site selection, spatial layout, construction techniques, and cultural inheritance. The cluster of stilted buildings (Diaojiao Lou in Mandarin Pinyin) in the Pengjia Village (meaning most of the villagers share the surname of Peng) is presented as a case study in this paper. The paper makes a case for their preservation as authentic carriers of the Tujia people’s cultural history, which is quickly disappearing due to development pressures. Three preservation strategies are discussed to meet this preservation goal. The first is to provide a detail analysis of the construction language to guarantee authenticity in the documentation, preservation and restoration processes of the stilted buildings. The second is to keep alive the expert knowledge and skill of traditional artisans by involving them in the construction of new structures using diaojiaolou techniques. The third strategy is to encourage local people to “dress-up” discordant buildings constructed mid to late 20th century with well-mannered facades using traditional details such as suspension columns, shuaqi, and six-panel and bang doors. Taking as a whole, these strategies are presented to help local residents, preservation experts, developers and policy makers sustain the irreplaceable cultural heritage and economic independence of the Tujia people.
The Pattern and Cost of Palliative Surgeries in Patients with Metastatic Melanoma  [PDF]
Zhongyun Zhao, Song Wang, Beth L. Barber
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.63027
Abstract:

Objective: To investigate the pattern of palliative surgeries and associated costs in patients with metastatic melanoma in the USA. Methods: This was a retrospective claims-based study of patients identified using administrative claims from MarketScan®?databases among patients with metastatic melanoma diagnosed between 2005 and 2011. Patient characteristics, patterns and cost of surgery, and length of hospital stay were evaluated. Results: Of the 2399 patients identified, 888 (37.0%) underwent at least one surgical procedure either in the outpatient or inpatient setting. The subgroup of patients who underwent surgery included significantly more patients with distant skin metastases compared to the subgroup who did not receive surgery; whereas significantly more patients in the non-surgery group had brain or bone metastases. Surgery performed in the outpatient setting was predominantly on the skin, whereas surgery on the brain was generally performed in the inpatient setting. The mean cost of the surgical procedures performed in the outpatient setting was $3393 (median: $1419) per procedure, which varied according to the location of the metastasis. For surgical procedures that were performed in the inpatient setting, the mean length of stay in hospital due to surgery was 4.4 (± 5.1) days, at a mean cost of $37,649 (median: $28,067) per hospitalization. Conclusions: Surgery is prevalent and costly in patients with metastatic melanoma.

MPSO Algorithm Based QoS Parameter Optimization for LTE Networks  [PDF]
F. L. Zhao, G. T. Chen
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2017, DOI: 10.4236/ijcns.2017.105B001
Abstract:
QoS Optimization is an important part of LTE SON, but not yet defined in the specification. We discuss modeling the problem of QoS optimization, improve the fitness function, then provide an algorithm based on MPSO to search the optimal QoS parameter value set for LTE networks. Simulation results show that the algorithm converges more quickly and more accurately than the GA which can be applied in LTE SON.
A self-assembling peptide RADA16-I integrated with spider fibroin uncrystalline motifs
Sun L, Zhao X
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S27428
Abstract: self-assembling peptide RADA16-I integrated with spider fibroin uncrystalline motifs Original Research (2742) Total Article Views Authors: Sun L, Zhao X Published Date February 2012 Volume 2012:7 Pages 571 - 580 DOI: http://dx.doi.org/10.2147/IJN.S27428 Received: 18 October 2011 Accepted: 24 November 2011 Published: 02 February 2012 Lijuan Sun1,2, Xiaojun Zhao1,3 1West China Hospital Laboratory of Nanomedicine and Institute for Nanobiomedical Technology and Membrane Biology, Sichuan University, Chengdu 610041, Sichuan, China; 2Dept of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, Guangdong, China; 3Center for Biomedical Engineering NE47-378, Massachusetts Institute of Technology, Cambridge, MA 02139-4307, USA Abstract: Mechanical strength of nanofiber scaffolds formed by the self-assembling peptide RADA16-I or its derivatives is not very good and limits their application. To address this problem, we inserted spidroin uncrystalline motifs, which confer incomparable elasticity and hydrophobicity to spider silk GGAGGS or GPGGY, into the C-terminus of RADA16-I to newly design two peptides: R3 (n-RADARADARADARADA-GGAGGS-c) and R4 (n-RADARADARADARADA-GPGGY-c), and then observed the effect of these motifs on biophysical properties of the peptide. Atomic force microscopy, transmitting electron microscopy, and circular dichroism spectroscopy confirm that R3 and R4 display -sheet structure and self-assemble into long nanofibers. Compared with R3, the -sheet structure and nanofibers formed by R4 are more stable; they change to random coil and unordered aggregation at higher temperature. Rheology measurements indicate that novel peptides form hydrogel when induced by DMEM, and the storage modulus of R3 and R4 hydrogel is 0.5 times and 3 times higher than that of RADA16-I, respectively. Furthermore, R4 hydrogel remarkably promotes growth of liver cell L02 and liver cancer cell SMCC7721 compared with 2D culture, determined by MTT assay. Novel peptides still have potential as hydrophobic drug carriers; they can stabilize pyrene microcrystals in aqueous solution and deliver this into a lipophilic environment, identified by fluorescence emission spectra. Altogether, the spider fibroin motif GPGGY most effectively enhances mechanical strength and hydrophobicity of the peptide. This study provides a new method in the design of nanobiomaterials and helps us to understand the role of the amino acid sequence in nanofiber formation.
Influence of cross-shelf water transport on nutrients and phytoplankton in the East China Sea: a model study
L. Zhao,X. Guo
Ocean Science Discussions (OSD) , 2010, DOI: 10.5194/osd-7-1405-2010
Abstract: A three dimensional coupled biophysical model was used to examine the supply of oceanic nutrients to the shelf of the East China Sea (ECS) and its role in primary production over the shelf. The model consisted of two modules: the hydrodynamic module was based on a nested model with a horizontal resolution of 1/18 degree, whereas the biological module was a low trophic level ecosystem model including two types of phytoplankton, three elements of nutrients, and biogenic organic material. Model results suggested that seasonal variation in chlorophyll-a had a strong regional dependence over the shelf of the ECS. The area with high chlorophyll-a appears firstly at the outer shelf in winter, and gradually migrates toward the inner shelf (offshore region of Changjiang estuary) from spring to summer. Vertically, chlorophyll-a was generally homogenous from the coastal zone to the inner shelf. In the middle and outer shelves, high chlorophyll-a appeared in the surface in spring but moved to the subsurface from summer to early autumn. The annual averaged onshore flux across the shelf break was estimated to be 1.53 Sv for volume, 9.4 kmol s 1 for DIN, 0.7 kmol s 1 for DIP, and 18.2 kmol s 1 for silicate, which are supplied mainly from the northeast of Taiwan and southwest of Kyushu. From calculations that artificially increased the concentration of nutrients in the Kuroshio water, the additional oceanic nutrients were distributed in the bottom layer from the shelf break to the region offshore of Changjiang estuary from spring to summer, and appeared in the surface layer from autumn to winter. The contribution of oceanic nutrients to primary production over the shelf was found not only in the surface layer (mainly at the outer shelf and shelf break in winter and in the region offshore of Changjiang estuary in summer) but also in the subsurface layer over the shelf from spring to autumn.
Corrigendum to "Influence of cross-shelf water transport on nutrients and phytoplankton in the East China Sea: a model study" published in Ocean Sci., 7, 27–43, 2010
L. Zhao,X. Guo
Ocean Science (OS) & Discussions (OSD) , 2011, DOI: 10.5194/os-7-111-2011
Abstract: No abstract available.
Influence of cross-shelf water transport on nutrients and phytoplankton in the East China Sea: a model study
L. Zhao,X. Guo
Ocean Science (OS) & Discussions (OSD) , 2011, DOI: 10.5194/os-7-27-2011
Abstract: A three dimensional coupled biophysical model was used to examine the supply of oceanic nutrients to the shelf of the East China Sea (ECS) and its role in primary production over the shelf. The model consisted of two parts: the hydrodynamic module was based on a nested model with a horizontal resolution of 1/18 degree, whereas the biological module was a lower trophic level ecosystem model including two types of phytoplankton, three elements of nutrients, and biogenic organic material. The model results suggested that seasonal variations occurred in the distribution of nutrients and chlorophyll a over the shelf of the ECS. After comparison with available observed nutrients and chlorophyll a data, the model results were used to calculate volume and nutrients fluxes across the shelf break. The annual mean total fluxes were 1.53 Sv for volume, 9.4 kmol s 1 for DIN, 0.7 kmol s 1 for DIP, and 18.2 kmol s 1 for silicate. Two areas, northeast of Taiwan and southwest of Kyushu, were found to be major source regions of oceanic nutrients to the shelf. Although the onshore fluxes of nutrients and volume both had apparent seasonal variations, the seasonal variation of the onshore nutrient flux did not exactly follow that of the onshore volume flux. Additional calculations in which the concentration of nutrients in Kuroshio water was artificially increased suggested that the oceanic nutrients were distributed in the bottom layer from the shelf break to the region offshore of the Changjiang estuary from spring to summer and appeared in the surface layer from autumn to winter. The calculations also implied that the supply of oceanic nutrients to the shelf can change the consumption of pre-existing nutrients from rivers. The response of primary production over the shelf to the oceanic nutrients was confirmed not only in the surface layer (mainly at the outer shelf and shelf break in winter and in the region offshore of the Changjiang estuary in summer) but also in the subsurface layer over the shelf from spring to autumn.
Expression of heat shock protein genes in insect stress responses
L Zhao,WA Jones
Invertebrate Survival Journal , 2012,
Abstract: The heat shock proteins (Hsps) that are abundantly expressed in insects are important modulators of insect survival. The expression of different Hsp genes are induced and modulated in insects in response to environmental inputs including abiotic stresses such as heat shock, ultraviolet radiation, chemical pesticides, as well as biotic stresses such as viruses, bacteria, fungi and other insects. This minireview will provide useful information related to the expression of Hsp genes in response to abiotic and biotic stressors as well as developmental regulation and modulation of Hsp genes involved with insect survival.
Klein-tunneling-enhanced directional coupler for Dirac electron wave in graphene
L. Zhao,Wenhui Duan
Physics , 2011,
Abstract: Using the coupled-mode theory in guided-wave optics and electronics, we explore a directional coupling structure composed of two parallel waveguides electrostatically induced by the split-gate technique in bulk graphene. Our results show that Klein tunneling can greatly enhance the coupling strength of the structure. By adjusting a gate voltage, the probability density of Dirac electron wave function initially in one waveguide can be completely transferred into the other waveguide within several hundred nanometers. Our findings could not only lead to functional coherent coupling devices for quantum-based electronic signal processing and on-chip device integration in graphene, but also shrink the size of the devices to facilitate the fabrication of graphene-based large-scale integrated logic circuits.
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