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Search Results: 1 - 10 of 485911 matches for " López-Sáez "
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Análisis palinológico del túmulo de Los Tiesos (Mediana de Voltoya, ávila).
López-Sáez, José Antonio
Munibe Antropologia-Arkeologia , 2011,
Abstract: El análisis palinológico del túmulo de Los Tiesos demuestra la existencia, durante el III milenio cal. BC, de un paisaje de dehesa con claro origen antropozoógeno sin evidencias de agricultura. Estos hechos permiten interpretar el monumento como un lugar de paso del ganado trasterminante en el marco cronocultural considerado.
Estudio palinológico de los sedimentos arqueológicos del yacimiento del Llanete de los Moros (Córdoba)
López García, Pilar,López-Sáez, José Antonio
Trabajos de Prehistoria , 1994,
Abstract: This paper present a pollen analysis from excavation at the Bronze Age site of Llanete de los Moros, with special reference to Vitis and Olea, and the presence of anthropic plants enabling the definition of distinct periods of the Holocene. The action of man seems to be present throughout the diagram. Se presentan los resultados del análisis paleopalinológico llevado a cabo en el yacimiento arqueológico del Llanete de los Moros, con una cronología arqueológica, encuadrable en la Edad del Bronce, y que lo sitúa climáticamente en el Subboreal-Subatlántico. Se pone de manifiesto una amplia representación de especies nitrófilas así como una cobertura arbórea poco manifiesta. Se comenta la presencia de Vitis y Olea.
Profesionales de la salud en países de la Unión Europea: el programa de intercambio HOPE Health professionals in countries of the European Union: the HOPE Exchange Programme
Ma Asunción López-Sáez y López de Teruel
Index de Enfermería , 2011,
Abstract:
Posible valor pronóstico de la hipertensión arterial en mujeres postmenopáusicas con cáncer de mama: Estudio piloto
López-Sáez,J. B.; Quintela Senra,D.; Senra Varela,A.;
Anales de Medicina Interna , 2001, DOI: 10.4321/S0212-71992001000300006
Abstract: background: the objective of this work was to determine the blood pressure of postmenopausal women with breast cancer in complete clinical remission of long duration. material and methods: it in a pilot study of case and controls, in which we meassure the blood pressure (bp) of 83 postmenopausal women, with breast cancer histologically confirmed, in complete clinical remission of long duration, recruited by consecutive sampling, to compare it with that of 70 normal postmenopausal women of the same age used as controls. they ara calculated the body mass index (bmi), the corporal surface, the confidence intervals (ci) of the means, the correlation between the bmi and the bp in both groups (breast cancer patients and normal control) and between the free disease interval and the systolic and diastolic blood pressures. results: the mean of the systolic bp in 93 breast cancer patients in complete clinical remission was 163 mm hg (95% ci 155-171) and in 70 normal controls was 134 mm hg (95% ci 129-139). the difference between both groups in statistically significant (p<0.001). the mean of the diastolic bp in the breast cancer patient in complete remission it was 98 mm hg (94-104) and in the normal controls was 78 mm hg (74-82). the difference between both groups was statistically significant (p<0.001). conclusions: this arterial hypertension, independent of the bmi and from the duration of the free disease interval, is associated with a long duration of the complete remission in postmenopausal breast cancer patients and consequently with a good prognostic of this disease.
Paleoenvironment during the upper Pleistocene at Vaucluse: palynological analysis of the lower layers of l′abri de la Combette (Bonnieux, Vaucluse, France)
López-Sáez, José Antonio,Texier, Pierre Jean,Thi Mai, Bui
Trabajos de Prehistoria , 1998,
Abstract: The palynological study of the La Combette rockshelter gives us information on the evolution of the vegetation surrounding the rock shelter area during the Upper Pleistocene (isotopic stage 3). Although widely dominated by Pinus sylvestris t. , mediterranean species are also present in the different climatic phases revealed by the catalysis. This confirms the refuge character of the area. [es] Paleoambiente durante el Pleistoceno Superior en Vaucluse: análisis palinológico de los niveles inferiores del abrigo de la Combette (Bonnieux, Vaucluse, Francia). El estudio palinológico del Abrigo de La Combette nos informa sobre la evolución seguida por la vegetación en el entorno del yacimiento durante el Pleistoceno Superior, Würm antiguo (inicio del estadio isotópico 3). Se ponen de manifiesto diversas fases climáticas caracterizadas, en general, por el dominio de Pinus sylvestris t. así como por la notable presencia de especies mediterráneas. Se constata el carácter de refugio de la zona estudiada. [fr] L'étude palynologique de l'abri de La Combette nous informe sur l'évolution de la végétation autour du site pendant le Pléistocène supérieur, au Würm ancien (début du stade isotopique 3). Les différentes phases climatiques mises en évidence sont caractérisées par la dominance du pin sylvestre et la présence notable d'espèces méditerranéennes. On constate le caractère refuge du site.
G2 repair and chromosomal damage in lymphocytes from workers occupationally exposed to low-level ionizing radiation
PINCHEIRA,J; LóPEZ,I; SANHUEZA,S; FERRUZ,P; NAVRRETE,MH; SANTOS,MJ; LóPEZ-SáEZ,JF;
Biological Research , 1999, DOI: 10.4067/S0716-97601999000400009
Abstract: the effect of the g2 repair of chromosomal damage in lymphocytes from workers exposed to low levels of x- or g-rays was evaluated. samples of peripheral blood were collected from 15 radiation workers, 20 subjects working in radiodiagnostics, and 30 healthy control donors. chromosomal aberrations (ca) were evaluated by scoring the presence of chromatid and isochromatid breaks, dicentric and ring chromosomes in lymphocytes with/without 5mm caffeine plus 3mm-aminobenzamide (3-ab) treatment during g2. our results showed that the mean value of basal aberrations in lymphocytes from exposed workers was higher than in control cells (p< 0.001). the chromosomal damage in g2, detected with caffeine plus 3-ab treatment was higher than the basal damage (untreated conditions), both in control and exposed populations (p< 0.05). in the exposed workers group, the mean value of chromosomal abnormalities in g2 was higher than in the control (p< 0.0001). no correlation was found between the frequency of chromosome type of aberrations (basal or in g2), and the absorbed dose. nevertheless, significant correlation coefficients (p< 0.05) between absorbed dose and basal aberrations yield (r = 0.430) or in g2 (r = 0.448) were detected when chromatid breaks were included in the total aberrations yield. under this latter condition no significant effect of age, years of employment or smoking habit on the chromosomal aberrations yield was detected. however, analysis of the relationship between basal aberrations yield and the efficiency of g2 repair mechanisms, defined as the percentage of chromosomal lesions repaired in g2, showed a significant correlation coefficient (r = -0.802; p< 0.001). these results suggest that in addition to the absorbed dose, the individual g2 repair efficiency may be another important factor affecting the chromosomal aberrations yield detected in workers exposed to low-level ionizing radiation
Retrospectiva del bosque de pino y encino de la Sierra Madre Occidental, Sonora, noroeste de México, hace 1000 a?os
Ortega-Rosas, Carmen Isela;Pe?alba, M. Cristina;López-Sáez, José Antonio;Van Devender, Thomas R.;
Acta botánica mexicana , 2008,
Abstract: the ciénega de camilo is a sphagnum palustre seep in a canyon in dense pine-oak forest with four species of pine and seven of oak in the sierra madre occidental of eastern sonora, mexico. analyses of pollen and non-pollen palynomorphs in two sediment cores show that pine-oak forest has been at the site during the last thousand years. when sedimentation began about 1000 years ago (1058 ±60 and 870 ±70 cal. bp (calibrated years before present)), pine was more abundant than today with an additional species with large pollen grains now present at higher elevation. the abundance and diversity of ferns were higher. non-pollen palynomorphs suggest moister (presence of copepoda), and eu- to mesotrophic conditions at the base, followed by drier conditions (unidentified amerospores, type 55a, zygnemataceae, and pediastrum), leading to the most recent mesotrophic-ombrotrophic environment characterized by pleospora, type 82e, and the sphagnum palustre seep. the inferred wet period at around 1000 cal. bp followed by drier and warmer climates is contemporaneous with the maximum development of the sonoran and chihuahuan desert archeological cultures.
Retrospectiva del bosque de pino y encino de la sierra madre occidental, sonora, noroeste de México, hace 1000 a os
Carmen Isela Ortega-Rosas,M. CrIstIna Pe?alba,José Antonio López-Sáez,Thomas R. Van Devender
Acta botánica mexicana , 2008,
Abstract: La Ciénega de Camilo es un humedal con Sphagnum palustre localizado en un bosque denso de pino y encino con cuatro especies de Pinus y siete de Quercus, en la Sierra Madre Occidental, en la región este de Sonora. Los análisis de polen y palinomorfos no polínicos de dos núcleos de sedimento muestran que el bosque de pino y encino ha existido en el lugar durante el último milenio. Sin embargo, hace alrededor de mil a os (1058 ±60 y 870 ±70 a os cal. BP (a os calibrados antes del presente)), el pino era más abundante que hoy día, y además crecía una especie de pino adicional, posiblemente del grupo de Pinus strobiformis, que hoy prospera a mayores elevaciones, en un clima más fresco y húmedo. Había abundancia y diversidad de helechos. Los palinomorfos no polínicos sugieren condiciones más húmedas (presencia de Copepoda) y eu- a mesotróficas en la base, seguidas por condiciones más secas (amerosporas indiferenciadas, tipo 55A, Zygnemataceae y Pediastrum), conducentes al medio ambiente mesotrófico-ombrotrófico más reciente caracterizado por Pleospora y tipo 82E, que refleja la ciénega de Sphagnum palustre. Se infiere que hubo un período húmedo hace alrededor de 1000 a os (14C BP), contemporáneo con el máximo desarrollo de las culturas arqueológicas de los desiertos Sonorense y Chihuahuense, que fue seguido por un clima progresivamente más seco y cálido.
Role of Angiotensin-(1-7) on Renal Hypertrophy in Streptozotocin-Induced Diabetes Mellitus  [PDF]
Dante Amato, Alma R. Nú?ez-Ortiz, José del Carmen Benítez-Flores, David Segura-Cobos, Pedro López-Sánchez, Beatriz Vázquez-Cruz
Pharmacology & Pharmacy (PP) , 2016, DOI: 10.4236/pp.2016.79046
Abstract:
Participation of angiotensin II in chronic kidney diseases including diabetic nephropathy (DN) has been extensively described. Similarly, several studies support a protective role for angiotensin-(1-7). However, other studies suggest that some of the cellular effects of angiotensin-(1-7) may be deleterious. The objective of this study was to determine the role of exogenous angiotensin-(1-7) on renal hypertrophy development in rats with streptozotocin-induced diabetes. A control group and three groups of rats with streptozotocin-induced diabetes: untreated diabetic rats, diabetic rats treated with captopril, and diabetic rats treated with angiotensin-(1-7), were studied. After two weeks of treatment, the kidneys were removed under anesthesia with pentobarbital. The kidneys were weighed and the renal cortex was separated for analysis of AT1R, TGF-β1, MASR, and ACE2 expression by western blot. Rats in the three groups with diabetes had hyperglycemia, increased food and water consumption, and higher urinary volume than control rats. Treatment with captopril or angiotensin-(1-7) reversed streptozotocin-induced renal hypertrophy, measured by kidney weight, protein/DNA ratio in renal cortex, glomerular area, or proximal tubular cells area, proteinuria, and creatinine clearance reduction. AT1R, TGF-β1, and MAS receptor expression in renal cortex of diabetic rats increased significantly as compared to controls (p < 0.05); treatment with captopril or angiotensin-(1-7) reversed such increments. ACE2 in the renal cortex decreased in diabetic rats, but it was increased after treatment with captopril or angiotensin-(1-7). These findings suggest that exogenous administration of angiotensin-(1-7) may be renoprotective in early stages of diabetes mellitus.
Effect of Cyclooxygenase-2 Blockade on Renal Hypertrophy Development during Early Diabetes Mellitus  [PDF]
Beatriz Vázquez-Cruz, Josseline Rangel-Veladiz, David Segura-Cobos, Pedro López-Sánchez, Maximiliano Ibarra-Barajas, Dante Amato
Pharmacology & Pharmacy (PP) , 2013, DOI: 10.4236/pp.2013.43042
Abstract:

Diabetes mellitus is the leading cause of diabetic nephropathy; the early phase of diabetes is associated with kidney growth and hyperfiltration; several factors modulate these changes, among them, prostaglandins and angiotensin II. Previous studies have shown that cyclooxygenase-2 is implicated in experimental models of diabetes. The aim of this work was to study the effect of celecoxib treatment on renal hypertrophy development in early diabetes mellitus. In our rats with early streptozotocin-induced diabetes there was renal hypertrophy, and increased renal expression of cyclooxygenase-2, AT1 receptor, and transforming growth factor-β1. Treatment with the selective cyclooxygenase-2 inhibitor celecoxib reduced the urinary excretion of prostaglandins such as prostaglandin E2, 6-keto prostaglandin F1α, and thromboxane B2. Kidney hypertrophy was reversed by the treatment, and the renal expression of cyclooxygenase-2, AT1 receptor, and transforming growth factor-β1 decreased. The renoprotective effects of celecoxib were independent of the changes in plasma glucose levels. These results confirm that cyclooxygenase-2 inhibition in rats with streptozotocin-induced diabetes decrease renal hypertrophy; this effect in turn, may be mediated by reduction of the expression of AT1 receptors and transforming growth factor-b1 in the kidney.

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