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Search Results: 1 - 10 of 6957 matches for " Kyung Hyun Cho "
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1,8-cineole protected human lipoproteins from modification by oxidation and glycation and exhibited serum lipid-lowering and anti-inflammatory activity in zebrafish
Kyung-Hyun Cho1,2,*
BMB Reports , 2012,
Abstract: We recently reported that a water extract of laurel or turmeric,1,8-cineole enriched fractions, showed hypolipidemic activityin the zebrafish model. Therefore, the present study investigatedthe cineole’s anti-oxidant and anti-inflammatory activitiesin lipoprotein metabolism in vitro and in vivo. Cineolehad inhibitory effects on cupric ion-mediated oxidation of lipoproteinsin general, while simultaneously enhancing ferric ionremoval ability in high-density lipoprotein (HDL). Hypercholesterolemiawas induced in zebrafish using cholesterol-feedingtreatment, 4% cholesterol, for 3 weeks. After feeding with orwithout the addition of cineole, the results revealed that cineolepossessed lipid-lowering and anti-inflammatory activitiesin hypercholesterolemic zebrafish. In addition, serum amyloidA and interleukin-6 levels were lowered and lipid accumulationwas decreased in the liver. Conclusively, 1,8-cineole wasfound to have anti-oxidant activities in lipoprotein metabolismboth in vitro and in vivo with simultaneous reduction of lipidaccumulation in the liver of zebrafish.
Abelian Chern-Simons field theory and anyon equation on a torus
Kyung-Hyun Cho,Chaiho Rim
Physics , 1993, DOI: 10.1103/PhysRevD.50.2870
Abstract: We quantize the abelian Chern-Simons theory coupled to non-relativistic matter field on a torus without invoking the flux quantization. Through a series of canonical transformations which is equivalent to solving the Gauss constraint, we obtain an effective hamiltonian density with periodic matter field. We also obtain the many-anyon Schr\"odinger equation with periodic Aharonov-Bohm potentials and analyze the periodic property of the wavefunction. Some comments are given on the different features of our approach from the previous ones.
Abelian Chern-Simons field theory and anyon equation on a cylinder
Kyung-Hyun Cho,Chaiho Rim
Physics , 1994,
Abstract: We present the anyon equation on a cylinder and in an infinite potential wall from the abelian Chern-Simons theory coupled to non-relativistic matter field by obtaining the effective hamiltonian through the canonical transformation method used for the theory on a plane and on a torus. We also give the periodic property of the theory on the cylinder.
Solvable Potentials from Supersymmetric Quantum Mechanics
Dong Sup Soh,Kyung Hyun Cho,Sang Pyo Kim
Physics , 1995,
Abstract: A recurrence relation of Riccati-type differential equations known in supersymmetric quantum mechanics is investigated to find exactly solvable potentials. Taking some simple {\it ans\"atze}, we find new classes of solvable potentials as well as reproducing the known shape-invariant ones.
On a multi-point Schwarz-Pick lemma
Kyung Hyun Cho,Seong-A Kim,Toshiyuki Sugawa
Mathematics , 2011,
Abstract: We consider the multi-point Schwarz-Pick lemma and its associate functions due to Beardon-Minda and Baribeau-Rivard-Wegert. Basic properties of the associate functions are summarized. Then we observe that special cases of the multi-point Schwarz-Pick lemma give Schur's continued fraction algorithm and several inequalities for bounded analytic functions on the unit disk.
Posturographic Evaluation of Dizziness Complaining Patients under Suspicion to Develop Parkinson's Disease  [PDF]
Hyun Cho
Neuroscience & Medicine (NM) , 2011, DOI: 10.4236/nm.2011.21004
Abstract: Although the typical clinical signs of Parkinson disease (PD) are tremor, rigidity, bradykinesia, and postural instability, PD is preceded by a preclinical phase during which neuronal degeneration develops without typical symptoms. More general nonspecific symptoms including dizziness have also been described to predate the typical PD signs for several years. All subjects were selected among patients in the Willis Hospital (Pusan, South of Korea), with complaints of diz-ziness from September 2009 to September 2010 and the baseline neurological screening and clinical ENT examination, to which the results were within the normal range. At baseline, 113 participants underwent neurological screening and provided information on dizziness. Of those participants, 103 were enrolled including 63 subjects in the control group. We used posturography. It allows quantitative assessment of vestibular-spinal component of body balance. The parame-ter of average speed of pressure center displacement to the lateral plan (VMX) and antero-posterior plan (VMY), which presented statistically significant differences between the groups except VMX with closed eyes. (p = 0.008 and p = 0.012, with closed eyes). With open eyes, only VMY showed significant difference between the groups (p = 0.010). In this study, the patients with dizziness and subjective complaints related to typical clinical signs of PD complaints presented higher instability in the orthostatic position than the control group of patients with dizziness and without such complaint. It could suggest that dizziness may be one symptom of preclinical PD and progress to overt postural instability. It is believed that a stepwise approach with a simple and inexpensive initial screening test of preclinical PD is required.
Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells
Sung-Hee Cho, Kyung-Sook Chung, Jung-Hye Choi, Dong-Hyun Kim, Kyung-Tae Lee
BMC Cancer , 2009, DOI: 10.1186/1471-2407-9-449
Abstract: We examined the effect of Compound K on the viabilities of various cancer cell lines using MTT assays. DAPI assay, Annexin V and PI double staining, Western blot assay and immunoprecipitation were used to determine the effect of Compound K on the induction of apoptosis.Compound K was found to inhibit the viability of HL-60 cells in a dose- and time-dependent manner with an IC50 of 14 μM. Moreover, this cell death had typical features of apoptosis, that is, DNA fragmentation, DNA ladder formation, and the externalization of Annexin V targeted phosphatidylserine residues in HL-60 cells. In addition, compound-K induced a series of intracellular events associated with both the mitochondrial- and death receptor-dependent apoptotic pathways, namely, (1) the activation of caspases-3, -8, and -9; (2) the loss of mitochondrial membrane potential; (3) the release of cytochrome c and Smac/DIABLO to the cytosol; (4) the translocation of Bid and Bax to mitochondria; and (5) the downregulations of Bcl-2 and Bcl-xL. Furthermore, a caspase-8 inhibitor completely abolished caspase-3 activation, Bid cleavage, and subsequent DNA fragmentation by Compound K. Interestingly, the activation of caspase-3 and -8 and DNA fragmentation were significantly prevented in the presence of cycloheximide, suggesting that Compound K-induced apoptosis is dependent on de novo protein synthesis.The results indicate that caspase-8 plays a key role in Compound K-stimulated apoptosis via the activation of caspase-3 directly or indirectly through Bid cleavage, cytochrome c release, and caspase-9 activation.Ginseng, the root and rhizomes of different Panax species (Araliaceae), is one of the most commonly used as traditional medicines in East Asia. Furthermore, the saponins of ginseng (ginsenosides) are its major active components and have been shown to possess anti-inflammatory, anti-tumor, and neuroprotective activities [1]. The pharmacological actions of these ginsenosides have been attributed to their bio
Seven-dimensional considerations of Einstein's connection. III. The seven-dimensional Einstein's connection
Mi Ae Kim,Keum Sook So,Chung Hyun Cho,Kyung Tae Chung
International Journal of Mathematics and Mathematical Sciences , 2003, DOI: 10.1155/s0161171203104024
Abstract: The purpose of the present paper is to prove a necessary and sufficient condition for a unique Einstein's connection to exist in 7-g-UFT and to display a surveyable tensorial representation of seven-dimensional Einstein's connection in terms of the unified field tensor, employing the powerful recurrence relations of the third kind obtained in earlier papers. All considerations in this paper are restricted to the first and second classes of X7, since the case of the third class, the simplest case, was already studied by many authors.
Seven-dimensional considerations of Einstein's connection. I. The recurrence relations of the first kind in --UFT
Mi Ae Kim,Keum Sook So,Chung Hyun Cho,Kyung Tae Chung
International Journal of Mathematics and Mathematical Sciences , 2003, DOI: 10.1155/s0161171203012766
Abstract: Einstein's connection in a generalized Riemannian manifold Xn has been investigated by many authors for lower-dimensional cases n=2,…,6. In a series of papers, we obtain a surveyable tensorial representation of 7-dimensional Einstein's connection in terms of unified field tensor, with main emphasis on the derivation of powerful and useful recurrence relations which hold in X7. In this paper, we give a brief survey of Einstein's unified field theory and derive the recurrence relations of the first kind which hold in a general Xn. All considerations in this paper are restricted to the first and second classes only since the case of the third class, the simplest case, was already studied by many authors.
Seven-dimensional considerations of Einstein's connection. II. The recurrence relations of the second and third kind in --UFT
Mi Ae Kim,Keum Sook So,Chung Hyun Cho,Kyung Tae Chung
International Journal of Mathematics and Mathematical Sciences , 2003, DOI: 10.1155/s0161171203104012
Abstract: We present powerful recurrence relations of the second and third kind which hold in 7-dimensional Einstein's generalized Riemannian manifold X7. All considerations in this paper are restricted to the first and second classes of X7 only since the case of the third class, the simplest case, was already studied by many authors.
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