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Search Results: 1 - 10 of 27193 matches for " Kyoung Jin Nho "
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Ethanol Extract of Dianthus chinensis L. Induces Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells In Vitro
Kyoung Jin Nho,Jin Mi Chun,Ho Kyoung Kim
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/573527
Abstract: Dianthus chinensis L. is used to treat various diseases including cancer; however, the molecular mechanism by which the ethanol extract of Dianthus chinensis L. (EDCL) induces apoptosis is unknown. In this study, the apoptotic effects of EDCL were investigated in human HepG2 hepatocellular carcinoma cells. Treatment with EDCL significantly inhibited cell growth in a concentration- and time-dependent manner by inducing apoptosis. This induction was associated with chromatin condensation, activation of caspases, and cleavage of poly (ADP-ribose) polymerase protein. However, apoptosis induced by EDCL was attenuated by caspase inhibitor, indicating an important role for caspases in EDCL responses. Furthermore, EDCL did not alter the expression of bax in HepG2 cells but did selectively downregulate the expression of bcl-2 and bcl-xl, resulting in an increase in the ratio of bax:bcl-2 and bax:bcl-xl. These results support a mechanism whereby EDCL induces apoptosis through the mitochondrial pathway and caspase activation in HepG2 cells.
Binary Ethylenimine Inactivated Japanese Encephalitis Virus Antigen Reveals Hemagglutination  [PDF]
Dong Kun Yang, Ha Hyun Kim, Jin Ju Nah, Kyoung Woo Lee, Jae Young Song
Open Journal of Veterinary Medicine (OJVM) , 2012, DOI: 10.4236/ojvm.2012.23020
Abstract: Severe climate change and global warming may impact significantly on vector-borne disease including Japanese encephalitis (JE) infection in human and animals. Thus, veterinary authority requires large quantity of diagnostic tools to survey vector-borne diseases. New producing method having a relation with JE antigen is needed to substitute conventional sucrose-acetone extraction method using suckling mouse. So, we developed new manufacturing method using polyethylene glycol (PEG) precipitation. Japanese encephalitis virus (JEV) was propagated in roller bottle containing Vero cell and inactivated with two kinds of inactivating reagents. Viability of the supernatant of bulk containing antigen was checked using Vero cell after inactivation. The supernatant did not show hemagglutination (HA) activity with goose erythrocytes. The antigen inactivated by binary ethylenimine (BEI) and concentrated by PEG precipitation method was found to be 2048 HA, but the antigen inactivated by 0.3% formaldehyde solution and concentrated by PEG precipitation method did not show HA titer. The antigen prepared from mice brain using sucrose-acetone extraction method showed 256 HA titer. This BEI inactivation method does not evoke animal welfare problem and can replace the conventional method that required biological hazardous reagents and suckling mice in preparing HA antigen. This new BEI inactivation method was safe in producing HA antigen against JEV in laboratory and can reduce environmental contamination of acetone.
One-Dimensional Oxide Nanostructures as Gas-Sensing Materials: Review and Issues
Kyoung Jin Choi,Ho Won Jang
Sensors , 2010, DOI: 10.3390/s100404083
Abstract: In this article, we review gas sensor application of one-dimensional (1D) metal-oxide nanostructures with major emphases on the types of device structure and issues for realizing practical sensors. One of the most important steps in fabricating 1D-nanostructure devices is manipulation and making electrical contacts of the nanostructures. Gas sensors based on individual 1D nanostructure, which were usually fabricated using electron-beam lithography, have been a platform technology for fundamental research. Recently, gas sensors with practical applicability were proposed, which were fabricated with an array of 1D nanostructures using scalable micro-fabrication tools. In the second part of the paper, some critical issues are pointed out including long-term stability, gas selectivity, and room-temperature operation of 1D-nanostructure-based metal-oxide gas sensors.
Cultural Omnivores’ Consumption: Strategic and Inclusively Exclusive
Yoo Jin Kwon,Kyoung-Nan Kwon
International Journal of Marketing Studies , 2013, DOI: 10.5539/ijms.v5n1p118
Abstract: This study explores cultural dispositions and consumption practices of cultural omnivores whose tastes align with those of high-status people in the U.S. Peterson and colleagues first identified the shift in status markers from snobbish and highbrow tastes to eclectic and omnivorous ones. Our findings suggest that cultural omnivores are characterized by two traits: superior self-perception in taste and cultural tolerance. These traits indicate that their prestige is sustained by their cultural styles, which are simultaneously broad and exclusive. Cultural omnivores also tend to engage in multifaceted experiences in food consumption and appearance-related goods (i.e., clothing), as well as Internet usage. We believe that the multiplicity observed in the current study reflects the highly strategic nature of the everyday consumption practices of cultural omnivores. We conclude that the qualities of elite consumers (i.e., cultural capital) are translated into omnivorous cultural consumption and a strategic and practical type of everyday consumption. The findings of this study have implications for marketing to high-status consumer segments characterized by a strong buying power and opinion leadership.
Effect of zinc injection on the corrosion products in nuclear fuel assembly  [PDF]
Jin-Soo Choi, Seung-Chul Park, Kyoung-Rok Park, Ho-Yeon Yang, O-Bong Yang
Natural Science (NS) , 2013, DOI: 10.4236/ns.2013.52027

The accumulation of corrosive and radioactive wastes in the primary system, including nuclear fuel assembly, significantly increases workers’ exposure to radiation. Zinc injection from 5 to 40 ppb into the Reactor Coolant System (RCS) of Pressurized Water Reactors (PWRs) has been known as an effective method to decrease the radiation fields and Primary Water Stress Corrosion Cracking (PWSCC). Zinc injection affects both corrosion product concentrations and characteristics of the deposited crud on oxide layers, because zinc is incorporated into the oxide films by displacing nickel, cobalt, and iron in primary systems. Radiation fields and corrosion might be mitigated as radioactive products, such as Co, which are removed by zinc injection. However, the zinc injection effects on fuel assembly in Nuclear Power Plants (NPPs) have not been much reported yet, even though some lab tests were carried out in USA and France. In this paper, we studied effects of zinc injection on the fuel assemblies in the Ulchin 1 NPP. The chemical and radiation analysis of radioactive corrosion products was performed to evaluate zinc injection effects on the fuel assembly in the Ulchin 1 NPP. Gamma spectroscopy was used to analyze crud samples for radioisotope contents. The Inductively Coupled Plasma-Atomic Emission Spectrometry (ICP-AES) was used to analyze crud samples for elemental contents. The concentration of radioisotope Co-58 was decreased after zinc injection to 1/22 times that before the zinc injection. 1% - 2% wt% of zinc was incorporated through the substitution of Ni in the crud oxide layer. The Ni/Fe ratio was decreased to 0.69 from 1.12 after the injection, due to the Ni substitution by zinc. It was found that NiO and NiFe2O4 were converted to ZnO and ZnFe2O4, respectively. In conclusion, zinc injecttion was found to be an essential method to reduce the amount of radioactive Co-58 in the fuel assemblies of primary systems in NPPs.

Biomass and Community Structure of Epilithic Biofilm on the Yellow and East Coasts of Korea  [PDF]
Bo Yeon Kim, Seo Kyoung Park, Jin Suk Heo, Han Gil Choi, Young Sik Kim, Ki Wan Nam
Open Journal of Marine Science (OJMS) , 2014, DOI: 10.4236/ojms.2014.44026
Abstract: Spatial biomass variation and community structure of epilithic biofilms were examined using cell counts, chlorophyll a extraction, and remote-sensing techniques. Samples were collected at two levels of wave exposure along the Yellow and East Coasts of Korea in December 2010. Cyanobacteria were dominant, occupying about 88% of biofilm, irrespective of wave exposure levels. The cyanobacteria species, Aphanotece spp. was abundant in the Yellow Coast location and Lyngbya spp. was abundant in the East coast location. The representative diatoms were Navicula spp. and Achnanthes spp. on the rocky shores of all study sites. Average Normalized Difference Vegetation Index (NDVI) was significantly greater in the Yellow Coast (mean 0.46) than that in the East Coast (mean 0.21); a similar pattern was observed in Vegetation Index (VI). Chlorophyll a content was three times greater on the Yellow Coast (20.50 μg/cm2) than that on the East Coast (8.21 μg/cm2), and it was greater at the Gosapo and Bangpo shore sites than that at the Gyeokpo site, on the Yellow Coast. However, chlorophyll a contents were not different between 23.33 and 17.66 μg/cm2 at exposed- and sheltered-shores of Yellow Coast, and were 9.62 μg/cm2 and 6.80 μg/cm2 on the East Coast. Vegetation indices were positively correlated with chlorophyll a contents. In conclusion, biofilm of Korean upper rocky shore was mainly composed of cyanobacteria and biofilm biomass that differed between the Yellow and East Coast.
Comparison of Depth Dose Distributions Using Cerenkov Fiber-Optic Dosimeter and Monte Carlo Simulation for HDR Brachytherapy  [PDF]
Sang Hun Shin, Young Beom Song, Mingeon Kim, Hye Jin Kim, Wook Jae Yoo, Kyoung Won Jang, Bongsoo Lee
Journal of Applied Mathematics and Physics (JAMP) , 2016, DOI: 10.4236/jamp.2016.48157
In this study, we fabricated a Cerenkov fiber-optic dosimeter (CFOD) without any scintillator to measure Cerenkov radiation signals owing to gamma-rays. The relative depth dose (RDD) distributions of Ir-192 HDR brachytherapy source were obtained by using the CFOD based on a subtraction method and the RDD curve was compared with the simulation result of Monte Carlo N-particle extended transport code (MCNPX). Finally, we demonstrated that the CFOD can be used to measure real-time dose information for HDR brachytherapy.
Antimicrobial activity and chemical components of two plants, Artemisia capillaris and Artemisia iwayomogi, used as Korean herbal Injin
Kyoung Sun Seo,Hyung Jin Jeong,Kyeong Won Yun
Journal of Ecology and Field Biology , 2010,
Abstract: This study compared the antimicrobial activity and chemical composition of two plants used as “Injin” (Korean herbalmedicine), namely, Injinho (Artemisia capillaris Thunberg) and Haninjin (Artemisia iwayomogi Kitamura). The ethyl acetateand ether fractions of crude methanol extracts from A. capillaris and A. iwayomogi were tested against three grampositivebacteria (Bacillus cereus, Bacillus subtilis, Staphylococcus aureus), two gram-negative bacteria (Escherichia coli,Pseudomonas fluorescens), and a yeast (Saccharomyceus cerevisiae). The antimicrobial activity of the ethyl acetate andether fraction of both plants was strong, but that of A. iwayomogi extracts was higher than that of A. capillaris extract forthe microbes tested. The minimum inhibitory concentration of the ether and ethyl acetate fraction of A. iwayomogi washighest for P. fluorescens and lowest for S. aureus and E. coli. We analyzed the chemical composition of the ethyl acetatefraction of A. capillaris and A. iwayomogi using gas chromatography-mass spectrometry. The main components of A.capillaris and A. iwayomogi were escoparone (86.82%) and scopoletin (20.47%), respectively.
Gluonic Structures of Tetraquarks
Jin Dong Kim,Su Kyoung Lee,Jong B. Choi
Physics , 2006,
Abstract: We formulate quantitative flux-tube overlap functions to account for the nonperturbative gluonic behaviors. In order to deduce systematic functional form, we introduce connection amplitude which can be defined between two boundary points occupied by quark or antiquark. With the deduced flux-tube overlap function, we can figure out long range gluonic structures of various quark combinations. In this paper, we report our calculated results for tetraquarks, $q^2 \bar{q}^2$, by considering two different configurations of boundary points for possible explanations of X(3872).
Atomic Scale Design and Three-Dimensional Simulation of Ionic Diffusive Nanofluidic Channels
Jin Kyoung Park,Kelin Xia,Guo-Wei We
Quantitative Biology , 2015,
Abstract: Recent advance in nanotechnology has led to rapid advances in nanofluidics, which has been established as a reliable means for a wide variety of applications, including molecular separation, detection, crystallization and biosynthesis. Although atomic and molecular level consideration is a key ingredient in experimental design and fabrication of nanfluidic systems, atomic and molecular modeling of nanofluidics is rare and most simulations at nanoscale are restricted to one- or two-dimensions in the literature, to our best knowledge. The present work introduces atomic scale design and three-dimensional (3D) simulation of ionic diffusive nanofluidic systems. We propose a variational multiscale framework to represent the nanochannel in discrete atomic and/or molecular detail while describe the ionic solution by continuum. Apart from the major electrostatic and entropic effects, the non-electrostatic interactions between the channel and solution, and among solvent molecules are accounted in our modeling. We derive generalized Poisson-Nernst-Planck (PNP) equations for nanofluidic systems. Mathematical algorithms, such as Dirichlet to Neumann mapping and the matched interface and boundary (MIB) methods are developed to rigorously solve the aforementioned equations to the second-order accuracy in 3D realistic settings. Three ionic diffusive nanofluidic systems, including a negatively charged nanochannel, a bipolar nanochannel and a double-well nanochannel are designed to investigate the impact of atomic charges to channel current, density distribution and electrostatic potential. Numerical findings, such as gating, ion depletion and inversion, are in good agreements with those from experimental measurements and numerical simulations in the literature.
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