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Search Results: 1 - 2 of 2 matches for " Kursaklioglu Hurkan "
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Letter to the Editor
Kursaklioglu Hurkan,Iyisoy Atila,Demirtas Ertan
Arquivos Brasileiros de Cardiologia , 2002,
Abstract:
Ocular changes in primary hypothyroidism
Banu T Ozturk, Hurkan Kerimoglu, Oguz Dikbas, Hamiyet Pekel, Mustafa S Gonen
BMC Research Notes , 2009, DOI: 10.1186/1756-0500-2-266
Abstract: Thirty-three patients diagnosed to have primary overt hypothyroidism were enrolled in the study. All subjects were assigned to underwent central corneal thickness (CCT), anterior chamber volume, depth and angle measurements with the Scheimpflug camera (Pentacam, Oculus) and cup to disc ratio (C/D), mean retinal thickness and mean retinal nerve fiber layer (RNFL) thickness measurements with optical coherence tomography (OCT) in addition to ophthalmological examination preceeding the replacement therapy and at the 1st, 3rd and 6th months of treatment.The mean age of the patients included in the study were 40.58 ± 1.32 years. The thyroid hormone levels return to normal levels in all patients during the follow-up period, however the mean intraocular pressure (IOP) revealed no significant change. The mean CCT was 538.05 ± 3.85 μ initially and demonstrated no statistically significant change as the anterior chamber volume, depth and angle measurements did. The mean C/D ratio was 0.29 ± 0.03 and the mean retinal thickness was 255.83 ± 19.49 μ initially and the treatment did not give rise to any significant change. The mean RNFL thickness was also stable during the control visits, so no statistically significant change was encountered.Neither hypothyroidism, nor its replacement therapy gave rise to any change of IOP, CCT, anterior chamber parameters, RNFL, retinal thickness and C/D ratio.The eye is a unique sensory organ that is prone to the effects of various systemic disorders. Hypothyroidism is one of these, presenting frequently with chemosis, periorbital edema and blepharoptosis. These changes, described as orbitopathy are attributed to the accumulation of hydrophilic mucopolysaccharides in the ground substance of dermis and other tissues leading to thickening which is called myxoedema [1].Another proposed, ocular finding of hypothyroidism is the intraocular pressure (IOP) rise. There has been a number of reports regarding the higher prevalance of primary open angle gl
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