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Search Results: 1 - 10 of 44177 matches for " Kun-Lin Lin "
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Phase Identification Using Series of Selected Area Diffraction Patterns and Energy Dispersive Spectrometry within TEM  [PDF]
Kun-Lin Lin
Microscopy Research (MR) , 2014, DOI: 10.4236/mr.2014.24008
Abstract: Transmission electron microscopy (TEM) is a very powerful technique for materials characteriza-tion, providing information relating to morphology, composition, and crystal structure. Selected area diffraction patterns (SADPs) are crystallographic data that can be obtained using a TEM in-strument. Conventional identification through SADP/TEM is tricky and tedious, thereby increasing the difficulty of phase identification. To establish a procedure for phase identification of known and unknown phases, in this study we examined two samples: one, a known phase, was Si with <100> alignment; the other, unknown, was the TixOy phase at the 96.4Au-3Ni-0.6Ti interlayer/ yttria-stabilized zirconia (YSZ) interface of a steel/96.4Au-3Ni-0.6Ti interlayer/YSZ joint. The procedures for phase identification of the known and unknown phases are described herein using a series of SADPs and energy dispersive spectrometry within TEM that would be useful for general researchers.
The Application of Value Analysis Based on Kano’s Two Dimensions Model and Value Expansion Model
Kun-Lin Hsieh
Information Technology Journal , 2009,
Abstract: How to obtain the useful Business Intelligence (BI) had known as an important work for most enterprises in Taiwanese, especial for the leisure industry. Hence, in this study, we will demonstrate a value analysis procedure based on the Kano’s two dimensions model and value expansion model to address such issue. Besides, an illustrative example owing to the leisure farming at Taitung area in Taiwan is also taken to demonstrate the feasibility and rationality of the proposed procedure. The important findings and conclusions in this study can be summarized as: (1) the Must-be values (keep health, self-satisfactory, leisure experience) for leisure farming case were mined by using the proposed Kano’s model; (2) the important products/services, benefits were obtained from the Must-be values by using the proposed value expansion model; (3) managers can know how to rationally and feasibly construct their corresponding competitive strategies for different customers’ clusters.
Employing Artificial Neural Networks into Achieving Parameter Optimization of Multi-Response Problem with Different Importance Degree Consideration
Kun-Lin Hsieh
Information Technology Journal , 2010,
Abstract: This study proposed a procedure based on Artificial Neural Networks (ANNs) technique with different importance degree consideration to address parameter optimization of a multiple responses problem. No matter what type of the experimental designs being employed, the proposed approach can be directly employed. Besides, the consistency and difference between those multiple responses can be also studied via the aggregation weight values in our proposed procedure. An illustrative example owing to the lead frame manufacturer in Taiwan is also employed to demonstrate the effectiveness and rationality of the proposed procedure.
Quantitative Evaluation of an Epitaxial Silicon-Germanium Layer on Silicon  [PDF]
Jie-Yi Yao, Kun-Lin Lin, Chiung-Chih Hsu
Microscopy Research (MR) , 2015, DOI: 10.4236/mr.2015.34006
Abstract: An epitaxial SixGey layer on a silicon substrate was quantitatively evaluated using rocking curve (RC) and reciprocal space map (RSM) obtained by powder X-ray diffraction (XRD), energy-dispersive X-ray spectroscopy (EDS) in conjunction with transmission electron microscopy (TEM), and EDS in conjunction with scanning electron microscopy (SEM). To evaluate the relative deviation of the quantitative analysis results obtained by the RC, RSM, SEM/EDS, and TEM/EDS methods, a standard sample comprising a Si0.7602Ge0.2398 layer on a Si substrate was used. The correction factor (K-factor) for each technique was determined using multiple measurements. The average and standard deviation of the atomic fraction of Ge in the Si0.7602Ge0.2398 standard sample, as obtained by the RC, RSM, TEM/EDS, and SEM/EDS methods, were 0.2463 ± 0.0016, 0.2460 ± 0.0015, 0.2350 ± 0.0156, and 0.2433 ± 0.0059, respectively. The correction factors for the RC, RSM, TEM/EDS, and SEM/EDS methods were 0.9740, 0.9740, 1.0206, and 0.9856, respectively. The SixGey layer on a silicon substrate was quantitatively evaluated using the RC, RSM, and EDS/TEM methods. The atomic fraction of Ge in the epitaxial SixGey layer, as evaluated by the RC and RSM methods, was 0.1833 ± 0.0007, 0.1792 ± 0.0001, and 0.1631 ± 0.0105, respectively. After evaluating the results of the atomic fraction of Ge in the epitaxial layer, the error was very small, i.e., less than 3%. Thus, the RC, RSM, TEM/EDS, and SEM/EDS methods are suitable for evaluating the composition of Ge in epitaxial layers. However, the thickness of the epitaxial layer, whether the layer is strained or relaxed, and whether the area detected in the TEM and SEM analyses is consistent must be considered.
Nanomechanical Characterization of Canine Femur Bone for Strain Rate Sensitivity in the Quasistatic Range under Dry versus Wet Conditions
Kun-Lin Lee,Marta Baldassarri,Nikhil Gupta,Dinesh Pinisetty
International Journal of Biomaterials , 2012, DOI: 10.1155/2012/415230
Identification of Grown-In Defects in CZ Silicon after Cu Decoration  [PDF]
Kun-Lin Lin, Yi-Ling Jian, Che-Yu Lin, Chien-Cheng Lin, Yih-Rong Luo, Chien-Chia Tseng
Microscopy Research (MR) , 2017, DOI: 10.4236/mr.2017.52002
Abstract: Bulk Czochralski silicon crystals were decorated with Cu and characterized by transmission electron microscopy (TEM) with energy-dispersive spectroscopy (EDS), atomic force microscopy (AFM), optical microscopy (OM), scanning electron microscopy (SEM), and photoluminescence spectroscopy (PL). The vacancy-type core, oxidation-induced stacking faults (OISF) ring, nearly defect-free ring, and self-interstitial-type rich outer ring were delineated in the Si crystal wafer. At the surface of the Si crystal, vertical-horizontal line (V-H line) defects and windmill defects (W-defects) were formed instead of OISF. The families of growth planes and directions were expressed as {011} and <110> for the V-H line and {010} and <010> for W-defects, respectively. In addition to V-H line defects and W-defects, pits or voids and Si oxide with dissolved Cu were found in the Si crystal wafer.
The Application of Structural Holes Theory to Supply Chain Network Information Flow Analysis
Chun-Nan Lin,Kun-Lin Hsieh,Jinsheng Roan,Chuan-Hung Kao
Information Technology Journal , 2011,
Abstract: This study used Honda supply chain as an illustrative case based on the social network perspective. We firstly examined the extent of structural holes of the chain members and then applied a heuristic approach to alleviate structural holes effects. Two important results were obtained as follows: (1) Many structural holes during the network structure for Honda supply chain because those members do not have many connections with each other. (2) A heuristic based on bridge-building concept was proposed to effectively resolve the structural holes problem of Honda supply chain.
Model Structure of Human APOBEC3G
Kun-Lin Zhang, Bastien Mangeat, Millan Ortiz, Vincent Zoete, Didier Trono, Amalio Telenti, Olivier Michielin
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000378
Abstract: Background APOBEC3G (apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G) has antiretroviral activity associated with the hypermutation of viral DNA through cytosine deamination. APOBEC3G has two cytosine deaminase (CDA) domains; the catalytically inactive amino-terminal domain of APOBEC3G (N-CDA) carries the Vif interaction domain. There is no 3-D structure of APOBEC3G solved by X-ray or nuclear magnetic resonance. Methodology/Principal Findings We predicted the structure of human APOBEC3G based on the crystal structure of APOBEC2. To assess the model structure, we evaluated 48 mutants of APOBEC3G N-CDA that identify novel variants altering ΔVif HIV-1 infectivity and packaging of APOBEC3G. Results indicated that the key residue D128 is exposed at the surface of the model, with a negative local electrostatic potential. Mutation D128K changes the sign of that local potential. In addition, two novel functionally relevant residues that result in defective APOBEC3G encapsidation, R122 and W127, cluster at the surface. Conclusions/Significance The structure model identifies a cluster of residues important for packaging of APOBEC3G into virions, and may serve to guide functional analysis of APOBEC3G.
Establishment of an early liver fibrosis model by the hydrodynamics-based transfer of TGF-β1 gene
Kun-Lin Yang, Kuo-Chen Hung, Wen-Teng Chang, Eric IC Li
Comparative Hepatology , 2007, DOI: 10.1186/1476-5926-6-9
Abstract: Using our hydrodynamics-based gene transfer model we found that upon induction by ZnSO4, the serum TGF-β1 level in Balb/c mice and Sp1 transcription factor binding activity peaked at 48 h and declined thereafter to a normal level on the 5th day. In addition, mRNA and protein levels of TGF-β1 in the liver were also upregulated at 48 h. Furthermore, induction of TGF-β1 increased the α-smooth muscle actin (α-SMA), p-Smad2/3, hydroxyproline and collagen 1A2 (Col 1A2) levels in the liver, suggesting a significant liver fibrosis.Our results show that TGF-β1 in pPK9a-transferred mice liver with ZnSO4 feeding can achieve a high expression level with significant fibrosis. However, since TGF-β1 induction is transient in our model, the fibrotic level does not reach a large scale (panlobular fibrosis) as seen in the CCl4-treated liver. Our model hence represents a dynamic and reversible liver fibrosis and could be a useful tool for studying early molecular mechanism of fibrogenesis or screening of antifibrotic drugs for clinical use.The development of liver fibrosis, particularly in the cirrhosis stage, is associated with high morbidity and mortality rates [1] and at present the only curative treatment for end stage liver cirrhosis is organ transplantation. The point at which cirrhosis or extensive fibrosis becomes irreversible has not been well defined [2], however, since liver fibrosis is a continuous process in both gene expression and histopathological alterations [3]. Generally accepted animal testing of liver fibrosis includes treatments with hepatotoxins such as carbon tetrachloride (CCl4). However, after the cessation of the long-term treatment of CCl4 for more than 4 weeks, pathological changes in the liver, such as inflammation, are reversed with the exception of fibrosis [3]. Many experimental long-term treatment models of liver fibrosis leading to cirrhosis have been useful for testing drug effectiveness but further studies are required to account for effects of dis
Growth and Flowering of the Regenerated Plsnta Induced by Zearalenone

Yao Kun-lin,Meng Fan-jing,

植物学报 , 1994,
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