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Search Results: 1 - 10 of 367 matches for " Krystyna Keleman "
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The Impact of High Temperature during Growing Season on Potato Cultivars with Different Response to Environmental Stresses  [PDF]
Krystyna Rykaczewska
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.412295
Abstract: Potato crop is the fourth main food crops in the world after maize, rice and wheat. It is characterized by specific temperature requirements and develops best at about 20°C. Forecasts of global warming prompt us to study the tolerance of potato genotypes to heat during the growing season. The aim of this work was to assess the response of chosen potato cultivars to high temperature during the different stages of plant growth under conditions of good soil moisture and drought. The impact of high temperature 32°C/25°C on potato plants was determined in pot experiment in three growth stages. A main measure of tolerance of the potato cultivars to high temperature during the growing season was an evaluation of the yield in relation to the Control combination. Here we demonstrated that tested potato cultivar’s response to high temperature during the growing season is dependent on the growth stage. The earlier it occurs, the more negative its impact on the growth and yield of potatoes is.
Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a
Jamie M. Kramer,Korinna Kochinke,Merel A. W. Oortveld,Hendrik Marks,Daniela Kramer,Eiko K. de Jong,Zoltan Asztalos,J. Timothy Westwood,Hendrik G. Stunnenberg,Marla B. Sokolowski,Krystyna Keleman,Huiqing Zhou,Hans van Bokhoven,Annette Schenck
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.1000569
Abstract: The epigenetic modification of chromatin structure and its effect on complex neuronal processes like learning and memory is an emerging field in neuroscience. However, little is known about the “writers” of the neuronal epigenome and how they lay down the basis for proper cognition. Here, we have dissected the neuronal function of the Drosophila euchromatin histone methyltransferase (EHMT), a member of a conserved protein family that methylates histone 3 at lysine 9 (H3K9). EHMT is widely expressed in the nervous system and other tissues, yet EHMT mutant flies are viable. Neurodevelopmental and behavioral analyses identified EHMT as a regulator of peripheral dendrite development, larval locomotor behavior, non-associative learning, and courtship memory. The requirement for EHMT in memory was mapped to 7B-Gal4 positive cells, which are, in adult brains, predominantly mushroom body neurons. Moreover, memory was restored by EHMT re-expression during adulthood, indicating that cognitive defects are reversible in EHMT mutants. To uncover the underlying molecular mechanisms, we generated genome-wide H3K9 dimethylation profiles by ChIP-seq. Loss of H3K9 dimethylation in EHMT mutants occurs at 5% of the euchromatic genome and is enriched at the 5′ and 3′ ends of distinct classes of genes that control neuronal and behavioral processes that are corrupted in EHMT mutants. Our study identifies Drosophila EHMT as a key regulator of cognition that orchestrates an epigenetic program featuring classic learning and memory genes. Our findings are relevant to the pathophysiological mechanisms underlying Kleefstra Syndrome, a severe form of intellectual disability caused by mutations in human EHMT1, and have potential therapeutic implications. Our work thus provides novel insights into the epigenetic control of cognition in health and disease.
Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a
Jamie M. Kramer,Korinna Kochinke,Merel A. W. Oortveld,Hendrik Marks,Daniela Kramer,Eiko K. de Jong,Zoltan Asztalos,J. Timothy Westwood,Hendrik G. Stunnenberg,Marla B. Sokolowski,Krystyna Keleman,Huiqing Zhou,Hans van Bokhoven ,Annette Schenck
PLOS Biology , 2011, DOI: 10.1371/journal.pbio.1000569
Abstract: The epigenetic modification of chromatin structure and its effect on complex neuronal processes like learning and memory is an emerging field in neuroscience. However, little is known about the “writers” of the neuronal epigenome and how they lay down the basis for proper cognition. Here, we have dissected the neuronal function of the Drosophila euchromatin histone methyltransferase (EHMT), a member of a conserved protein family that methylates histone 3 at lysine 9 (H3K9). EHMT is widely expressed in the nervous system and other tissues, yet EHMT mutant flies are viable. Neurodevelopmental and behavioral analyses identified EHMT as a regulator of peripheral dendrite development, larval locomotor behavior, non-associative learning, and courtship memory. The requirement for EHMT in memory was mapped to 7B-Gal4 positive cells, which are, in adult brains, predominantly mushroom body neurons. Moreover, memory was restored by EHMT re-expression during adulthood, indicating that cognitive defects are reversible in EHMT mutants. To uncover the underlying molecular mechanisms, we generated genome-wide H3K9 dimethylation profiles by ChIP-seq. Loss of H3K9 dimethylation in EHMT mutants occurs at 5% of the euchromatic genome and is enriched at the 5′ and 3′ ends of distinct classes of genes that control neuronal and behavioral processes that are corrupted in EHMT mutants. Our study identifies Drosophila EHMT as a key regulator of cognition that orchestrates an epigenetic program featuring classic learning and memory genes. Our findings are relevant to the pathophysiological mechanisms underlying Kleefstra Syndrome, a severe form of intellectual disability caused by mutations in human EHMT1, and have potential therapeutic implications. Our work thus provides novel insights into the epigenetic control of cognition in health and disease.
Ultrastructural changes in chloroplasts of mesophyll cells of chlorotic and prematurely yellowed leaves of Betula pendula Rothr
Krystyna Przyby?,Krystyna Idzikowska
Acta Societatis Botanicorum Poloniae , 2003, DOI: 10.5586/asbp.2003.037
Abstract: The ultrastructure of chloroplasts was studied in mesophyll cells of the leaves of silver birch (Betula pendula) showing interveinal chlorosis or premature yellowing, in comparison with leaves without symptoms or exhibiting symptoms of natural senescence. The leaves were collected between May 26 to June 7 and additionally in the September 10-12 from the upper part of the crown, from increments of the past four years. No major difference in ultrastructure of chloroplasts was found between spongy and palisade mesophyll cells. The following senescencerelated changes were observed in chloroplasts of prematurely yellowed leaves and showing inteveinal chlorosis: reduced chloroplast size, degeneration of the membrane systems of thylakoids and increased electron density of plastoglobuli. The most electron dark globules (lipid droplets) were found together with starch grains in cells of spongy mesophyll of leaves showing interveinal chlorosis. Abnormal, spherical and rounded chloroplasts with electron-dark inside of thylakoids or the electron-dark stroma between thylakoids were found only in yellowed and chlorotic leaves in spring.
Participatory System Dynamics Modeling for Sustainable Environmental Management: Observations from Four Cases
Krystyna Stave
Sustainability , 2010, DOI: 10.3390/su2092762
Abstract: Sustainable environmental management requires a decision support approach that accounts for dynamic connections between social and ecological systems, integrates stakeholder deliberation with scientific analysis, incorporates diverse stakeholder knowledge, and fosters relationships among stakeholders that can accommodate changing information and changing social and environmental conditions. Participatory system dynamics modeling provides such a framework. It supports stakeholder learning about the system and the perspectives of other stakeholders, and can help build social capital among stakeholders. Four cases of participatory system dynamics modeling, which range from no to full participant involvement in model development, support the idea that greater social capital development results from greater participation in model development, but also suggest that even the simplest use of simulation models in a group fosters stakeholder learning about the system through surprise and discovery. To maximize the learning value of simulation models, it is important to allow enough time for debriefing the “aha!” moments that lead to curiosity about system behavior. To maximize social capital development, it is important to build enough time into the problem structuring and model conceptualization phases for stakeholders to articulate their mental models and examine those of other participants.
A New Locality of Macrogastra ventricosa (Draparnaud, 1801) (Gastropoda: Pulmonata: Clausiliidae) in Wielkopolska (Poland)
Krystyna Szybiak
Folia Malacologica , 2009, DOI: 10.2478/v10125-009-0004-1
Abstract: Macrogastra ventricosa, previously known only as subfossil in central Poland, was found in an alder forest in the erkowsko-Czeszewski Landscape Park.
An Unusual Preferences Among Regression Designs
Krystyna Maciagxxn'
The Open Statistics & Probability Journal , 2009, DOI: 10.2174/1876527000901010001]
Abstract: Consider the classical regression design with one explanatory variable taking values x = (x1 ,…, xn )' and an alternative design based on Tx, where We reveal an interesting phenomenon that the second design is better, from many reasonable points of view, than the initial one.
The Course and Didactic Results of Master's Studies in Physical Education
Krystyna Buchta
Polish Journal of Sport and Tourism , 2011, DOI: 10.2478/v10197-011-0006-6
Abstract: Introduction. The aim of the study was to analyse the effect of Physical Education (PE) studies at the Faculty of Physical Education and Sport (FPE&S) of the University of Physical Education (UPE) in Warsaw. Material and methods. The study was carried out among the students and graduates of two unified education cycles by means of the documents analysis and the diagnostic poll method with the use of a posted questionnaire. The analysis encompassed the level of preparation for undertaking the studies, academic merits, sport achievements, other experience gained by the examined in the course of the studies and the "output effect" in the form of gained competences. Results. As a result of the study, it was established that the PE studies were undertaken mostly by physically well-prepared graduates of secondary schools whose level of theoretical knowledge was quite low. In the course of the studies, the examined scored average academic merits. The studies constituted for them an opportunity to gain new competences, mainly in the field of physical education. Sporadically, students' activities were directed at educational, organisational and social spheres. Conclusions. In the light of the obtained results, amendments in the national curriculum and changes in physical education teaching methodology seem crucial. Apart from gaining competences pertaining to a particular graduate's profile, development of creative skills, and shaping the proper attitude and behaviour seem vital.
Choroba trzewna, wspó czesny obraz kliniczny i diagnostyka
Krystyna Karczewska
Pediatria Wspó?czesna , 2006,
Abstract: Celiakia jest chorob uwarunkowan genetycznie, wywo an nieprawid ow odpowiedzi immunologiczn na spo ywany gluten, zawart w nim gliadyn i inne prolaminy.
Leczenie ywieniowe w nieswoistych zapaleniach jelit u dzieci
Krystyna Grzybowska
Pediatria Wspó?czesna , 2007,
Abstract: Nieswoiste zapalenia jelit (n.z.j.) to grupa chorób o przewlek ym procesie zapalnym, w ród których najcz ciej mamy do czynienia z wrzo-dziej cym zapaleniem jelita grubego (w.z.j.g.) i chorob Le niowskiego-Crohna (ch. L-C). Obydwie choroby o nieustalonej etiopatogene-zie. Udzia czynnika ywieniowego wskazywany jest w patomechanizmie tych chorób. W leczeniu n.z.j. prócz post powania farmakologicznego wa n rol odgrywa leczenie ywieniowe, którego mo liwo ci w zale no ci od przebiegu klinicznego chorób przedstawiono w pracy.
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