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Search Results: 1 - 10 of 193635 matches for " Krishna Mohan G* "
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HEPATOPROTECTIVE EFFECT OF SOLENA AMPLEXICAULIS (TUBER) ON ACUTE CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY
Krishna Mohan G*
International Journal of Pharmacy and Technology , 2010,
Abstract: The hepatoprotective activity of methanolic extract of Solena amplexicaulis (SAME) (Lam.)Gandhi (Cucurbitaceae) at doses of 250 mg/kg and 500 mg/kg were evaluated by carbon tetrachloride(CCl4) intoxication in rats. The toxic group which received CCl4 (0.3 ml/kg of CCl4 dissolved in 1:1 ratio in olive oil by subcutaneous (s.c) alone exhibited significant increase in serum alanine aminotransferase(ALT), aspartate amino transferase (AST), alkaline phosphatase (ALP) and total bilirubin (TB) levels. It also caused significant (P<0.001) decrease in protein levels. The groups receivedpretreatment of SAME at a dose of 500 mg/kg b.w.p.o. had controlled the AST, ALT, ALP and total bilirubin levels and the effects were comparable with standard drug (silymarin 100 mg/kg b.w.p.o).The total protein (TP) and albumin (ALB) levels were significantly increased in the animals received pretreatment of the extract at the higher dose level. The animals received pretreatment of the extractshown decreased necrotic zones and hepatocellular degeneration when compared to the liver exposed to CCl4 intoxication alone. Thus the histopathalogical studies also supported the protective effect ofthe extract.
Network of Earthquakes and Recurrences Therein
T. R. Krishna Mohan,P. G. Revathi
Physics , 2010, DOI: 10.1007/s10950-010-9208-5
Abstract: We quantify the correlation between earthquakes and use the same to distinguish between relevant causally connected earthquakes. Our correlation metric is a variation on the one introduced by Baiesi and Paczuski (2004). A network of earthquakes is constructed, which is time ordered and with links between the more correlated ones. Data pertaining to the California region has been used in the study. Recurrences to earthquakes are identified employing correlation thresholds to demarcate the most meaningful ones in each cluster. The distribution of recurrence lengths and recurrence times are analyzed subsequently to extract information about the complex dynamics. We find that the unimodal feature of recurrence lengths helps to associate typical rupture lengths with different magnitude earthquakes. The out-degree of the network shows a hub structure rooted on the large magnitude earthquakes. In-degree distribution is seen to be dependent on the density of events in the neighborhood. Power laws are also obtained with recurrence time distribution agreeing with the Omori law.
Earthquake Correlations and Networks- A Comparative Study
T. R. Krishna Mohan P. G.,Revathi
Physics , 2010,
Abstract: We quantify the correlation between earthquakes and use the same to distinguish between relevant causally connected earthquakes. Our correlation metric is a variation on the one introduced by Baiesi and Paczuski (2004). A network of earthquakes is constructed, which is time ordered and with links between the more correlated ones. Recurrences to earthquakes are identified employing correlation thresholds to demarcate the most meaningful ones in each cluster. Data pertaining to three different seismic regions, viz. California, Japan and Himalayas, are comparatively analyzed using such a network model. The distribution of recurrence lengths and recurrence times are two of the key features analyzed to draw conclusions about the universal aspects of such a network model. We find that the unimodal feature of recurrence length distribution, which helps to associate typical rupture lengths with different magnitude earthquakes, is robust across the different seismic regions. The out-degree of the networks shows a hub structure rooted on the large magnitude earthquakes. In-degree distribution is seen to be dependent on the density of events in the neighborhood. Power laws, with two regimes having different exponents, are obtained with recurrence time distribution. This is in agreement with the Omori law for aftershocks and extends it to spatial recurrences. The crossover to the second power law regime can be taken to be signalling the end of aftershock regime in an objective fashion.
A CONCEPTUAL DESIGN OF WIND FRICTION REDUCTION ATTACHMENTS TO THE REAR PORTION OF A CAR FOR BETTER FUEL ECONOMY AT HIGH SPEEDS
D.Krishna Mohan Raju,Dr. G.Jayachandra Reddy
International Journal of Engineering Science and Technology , 2012,
Abstract: Normally all the car bodies are streamlined for very less wind drag coefficient, but still due to the length of car as constraint the rear portion of the car was not fully streamlined. The present paper objective is to design the wind friction reduction attachments to the rear portion of a car which can be opened and closed depending onthe requirement, thereby mileage of the vehicle at high speeds will be improved and the car can travel at higher speeds without increasing the engine capacity. The rear attachments of car can be closed in traffic and parking periods and when the vehicle is travelling on highways at high speed, the attachments are opened. To open and close the wind friction reduction attachments a hydraulic system is designed. The wind friction reduction attachments are designed to be inside the rear door in the closed condition so that there won’t be any problem in aesthetic point of view.
Effect of Root Extract Fractions of Kyllinga triceps Rottb on Streptozotocin Induced Diabetic Rats
Swaroopa Rani Vanapatla,G Krishna Mohan,B Ravi Kumar
Stamford Journal of Pharmaceutical Sciences , 2011,
Abstract: The present study was aimed to evaluate the root extract fractions of Kyllinga triceps (KT) for their antidiabetic potential on streptozotocin induced diabetes in neonatal rats. Diabetes was induced by a single intraperitoneal injection of Streptozotocin (90mg/kg) to 48±2h old neonatal rats. Effect of root extract fractions (toluene, ethyl acetate, 1- butanol at 50 &100 mg/kg.) were tested for their antihyperglycemic activity by measuring their fasting blood glucose level in diabetic rats at 0,2,4,6,8,12 & 24 h after the treatment. In sub acute study ethyl acetate fraction of KT (EAKT) was administered daily to diabetic rats orally at a dose of 100mg/kg for 28 days. Body weight of the animals and blood glucose level were observed at weekly interval during the study. Cholesterol, triglycerides, insulin, SGPT, ALP, creatinine and total proteins level in serum were also estimated at the initial and after 28 days of the treatment. As the preliminary investigation conducted in our lab on methanolic extract of the roots of KT had showed significant oral glucose tolerance with 200 mg/kg in normal rats. Oral administration of fractions of the plant significantly reduced the fasting blood glucose level in diabetic rats. Among the fractions, EAKT was found to be more effective. Further, in sub-acute study, EAKT, showed a significant anti diabetic activity by reversal of the altered afore said serum biochemical parameters. The results of the study are substantiating the traditional claim of the roots of Kyllinga triceps in the treatment of diabetes with a scope for development of antidiabetic herbal drug from EAKT.
SPC for Software Reliability-Imperfect Software Debugging Model
R Satya Prasad,N Supriya,G Krishna Mohan
International Journal of Computer Science Issues , 2011,
Abstract: Software reliability process can be monitored efficiently by using Statistical Process Control (SPC). It assists the software development team to identify failures and actions to be taken during software failure process and hence, assures better software reliability. In this paper, we consider a software reliability growth model of Non-Homogenous Poisson Process (NHPP) based, that incorporates imperfect debugging problem. The proposed model utilizes the failure data collected from software development projects to analyze the software reliability. The maximum likelihood approach is derived to estimate the unknown point estimators of the model. We investigate the model and demonstrate its applicability in the software reliability engineering field.
ANTI-FERTILITY ACTIVITY OF WHOLE PLANT EXTRACT OF SARCOSTEMMA SECAMONE (L) BENNET ON MALE ALBINO RATS
Thanga Krishna Kumari S,Sakthidevi G,Muthukumaraswamy S,Mohan VR
International Research Journal of Pharmacy , 2012,
Abstract: Anti-fertility effect of ethanol extract of whole plant extract of Sarcostemma secamone was observed in male albino rats. The relative weight of the testes and epididymis were decreased. The epididymal sperm count, motility and sperm abnormality were reduced significantly in treated rats. There was an increase in serum protein, albumin, globulin, urea, creatinine and the activity of liver marker enzymes (SGOT, SGPT and ALP) levels of control and treated rats. The activities of serum antioxidants (CAT, SOD, GPx, GST and GRD) in plant extract treated rats were decreased. The results of the hormonal assay showed that increased serum levels of FSH and estrogen but decreased in the serum levels of LH and testosterone compared to control. The results of fertility test indicated that the treated adult male rats reduced the number of female’s impregnation. In addition, the number of implantations and the number of viable featuses were also decreased. The results of the present study concluded that, ethanol extract of whole plant of Sarcostemma secamone inhibited sperm concentration, motility and testosterone which might result in a male fertility.
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF FAROPENEM IN BULK AND PHARMACEUTICAL FORMULATION USING THE RP-HPLC METHOD
Iffath Rizwana,K. Vanitha Prakash,G. Krishna Mohan
International Research Journal of Pharmacy , 2012,
Abstract: A simple, specific and accurate reverse phase high performance liquid chromatographic method was developed for the determination Faropenem in Bulk and pharmaceutical dosage form. The column used was Symmetry C18 (4.6 x 150mm, 5 m, Make: ODS) or equivalent in isocratic mode, with mobile phase containing phosphate buffer adjusted the pH-4.0 with orthophosphoric acid and Acetonitrile in the ratio (70:30%v/v) the flow rate was 0.9 mL/ min and eluents was monitored at 317 nm. The retention time Faropenem was 3.051 min, respectively. The linearity for Faropenem was in the range of 40-120 μg/ml respectively. The recovery of Faropenem was found to be 100.1%, respectively. The proposed method was validated and successfully applied to the estimation of Faropenem in tablet dosage form.
Integer Wavelet Transform and Predictive Coding Technique for Lossless Medical Image Compression
Vineeta Gupta,A.G. Rao,Krishna Mohan Pandey
International Journal of Technological Exploration and Learning , 2013,
Abstract: Lossless image compression has one of its important application in the field of medical images. Enormous amount of data is created by the information present in the medical images either in multidimensional or multiresolution form.Efficient storage, transmission, management and retrieval of the voluminous data produced by the medical images has nowadays become increasingly complex.Solution to the complex problem lies in the lossless compression of the medical data .Medical data is compressed in such a way so that the diagnostics capabilities are not compromised or no medical information is lost.This paper proposes a hybrid technique for lossless medical image compression that combines integer wavelet transforms and predictive coding to enhance the performance of lossless compression. Here we will first apply the integer wavelet transform and then predictive coding to each subband of the image obtained as an output to lifting scheme.Measures such as entropy,scaled entropy and compression ratio are used to evaluate the performance of the proposed technique.
Distributed Video Coding: CODEC Architecture and Implementation
Vijay Kumar Kodavalla,P.G. Krishna Mohan
Signal & Image Processing , 2011,
Abstract: Distributed Video Coding (DVC) is a new coding paradigm for video compression, based on Slepian-Wolf (lossless coding) and Wyner-Ziv (lossy coding) information theoretic results. DVC is useful foremerging applications such as wireless video cameras, wireless low-power surveillance networks anddisposable video cameras for medical applications etc. The primary objective of DVC is low-complexityvideo encoding, where bulk of computation is shifted to the decoder, as opposed to low-complexitydecoder in conventional video compression standards such as H.264 and MPEG etc. There are couple ofearly architectures and implementations of DVC from Stanford University[2][3] in 2002, BerkeleyUniversity PRISM (Power-efficient, Robust, hIgh-compression, Syndrome-based Multimedia coding)[4][5]in 2002 and European project DISCOVER (DIStributed COding for Video SERvices)[6] in 2007.Primarily there are two types of DVC techniques namely pixel domain and transform domain based.Transform domain design will have better rate-distortion (RD) performance as it exploits spatialcorrelation between neighbouring samples and compacts the block energy into as few transformcoefficients as possible (aka energy compaction). In this paper, architecture, implementation details and“C” model results of our transform domain DVC are presented.
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