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Search Results: 1 - 10 of 223673 matches for " Konwar R "
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E-endocrinology: An update
Konwar R,Singh M,Bid H
Indian Journal of Medical Sciences , 2008,
Abstract: Internet, from a long time, has opened up a myriad resource of knowledge and applications for academicians, researchers and clinicians alike in all health care professions across the globe. Basic endocrinologists are exploring through bench-top protocols to understand endocrine system and to design therapeutic interventions. Clinicians are required to continuously look for new developments relating to investigation, diagnosis and therapeutic options in their everyday practice for better quality of life of patients. All these require managing a large body of information. Now, these innovative technologies have opened up newer avenues for endocrinologists. As internet is serving the backbone for modern technologies, it is of utmost necessity to use and refine internet applications for future endocrinologists. Increasingly, easy access to internet has dramatically reduced barriers in sharing information among basic and clinical endocrinologists. Considering the growing scope for endocrinologists in the use of internet, it is necessary to understand internet as a source of information and backbone of modern applications. This review illustrates the expanding roles of the internet for endocrinologists and provides a ready-to-use compilation of useful academic, research, clinical resources, and is expected to introduce, stimulate and guide endocrinologists into the realm of WWW.
Endocrinological cancers and the internet
Bid H,Konwar R,Kumar S
Indian Journal of Cancer , 2009,
Abstract: Endocrine cancers are some of the commonest forms of cancer getting mention as early as in old papyruses of Egypt. Our current knowledge about this cluster of cancer has grown immensely with improved survival rates. In the era of specialization and super specialization, we started peeking into these conditions more elaborately and beyond microscopically. The growing awareness demanded categorization of information into disease basics like molecular pathology of initiation and progression; advanced diagnostics; new therapeutic options; patient awareness and involvement in clinical trials. Recent advances in genomics and hereditary counseling have delineated pre-disease forecasting possibilities. With advanced diagnostics and therapeutic modalities, we saw an increase in cancer survivors demanding extra care and moral support. Throughout these developments, we went through a boost in global information communications, the main thrust being the Internet. Networking of computers globally generated a platform that created a ripple of knowledge far and wide. The purpose of this review is to investigate how the Internet is supporting the growth and development of the field of endocrine cancer, and present and future scope of the Internet as a tool for professionals involved in this area. The information furnished here were collected from cited references as well as all websites mentioned in the tables.
A New less Expensive Method for Genome Size Determination of Plants
B.K. Konwar,D. Chowdhury,J. Buragohain,R. Kandali
Asian Journal of Plant Sciences , 2007,
Abstract: A new method has been developed for easy and inexpensive determination of nuclear DNA content or genome size of plants. This method requires the determination of average cell volume, the number of cells present in a leaf tissue with known weight and intercellular space of the plant species. The nuclear DNA content in a single cell can be calculated easily by dividing the amount of genomic DNA present in a tissue section by the total number of cells in the same tissue. The genome size of five plant species has been determined both by this method and by flow cytometry. The results were found comparable from the accuracy point of view.
Association of glutathione S-transferase (GSTM1, T1 and P1) gene polymorphisms with type 2 diabetes mellitus in north Indian population
Bid H,Konwar R,Saxena M,Chaudhari P
Journal of Postgraduate Medicine , 2010,
Abstract: Background: Diabetes mellitus is associated with an increased production of reactive oxygen species (ROS) and a reduction in antioxidant defense. The oxidative stress becomes evident as a result of accumulation of ROS in conditions of inflammation and Type 2 diabetes mellitus (T2DM). The genes involved in redox balance, which determines the susceptibility to T2DM remain unclear. In humans, the glutathione S-transferase (GST) family comprises several classes of GST isozymes, the polymorphic variants of GSTM1, T1 and P1 genes result in decreased or loss of enzyme activity. Aims: The present study evaluated the effect of genetic polymorphisms of the GST gene family on the risk of developing T2DM in the North Indian population. Settings and Design: GSTM1, T1 and P1 polymorphisms were genotyped in 100 T2DM patients and 200 healthy controls from North India to analyze their association with T2DM susceptibility. Materials and Methods: Analysis of GSTM1 and GSTT1 gene polymorphisms was performed by multiplex polymerase chain reaction (PCR) and GSTP1 by PCR-Restriction Fragment Length Polymorphism (RFLP). Statistical Analysis: Fisher′s exact test and χ2 statistics using SPSS software (Version-15.0). Results: We observed significant association of GSTM1 null (P=0.004, OR= 2.042, 95%CI= 1.254-3.325) and GSTP1 (I/V) (P=0.001, OR= 0.397, 95%CI=0.225-0.701) with T2DM and no significant association with GSTT1 (P=0.493). The combined analysis of the three genotypes GSTM1 null, T1 present and P1 (I/I) demonstrated an increase in T2DM risk (P= 0.005, OR= 2.431 95% CI=1.315-4.496). Conclusions: This is the first study showing the association of a combined effect of GSTM1, T1 and P1 genotypes in a representative cohort of Indian patients with T2DM. Since significant association was seen in GSTM1 null and GSTP1 (I/V) and multiple association in GSTM1 null, T1 present and P1 (I/I), these polymorphisms can be screened in the population to determine the diabetic risk.
A Possible Realization of Chlorophyll Lase  [PDF]
Mitali Konwar, G. D. Baruah
Optics and Photonics Journal (OPJ) , 2013, DOI: 10.4236/opj.2013.38060

The present work is concerned with a description of strong fluorescence from a sample of Alocasia culcullata schot (local name Kolia kasu) and possible realization of chlorophyll laser. The red florescence is most prominent when excited with broad band source like 30 mW green or blue solid state laser, but the acetone extract of plant leaves Allocasa cullcuta schot unusually exhibits the strong intensity in the red sector of the spectrum. A dark room can be easily illuminated with this red radiation. We have used this fact to explore a possible realization of chlorophyll laser which would be a natural environmental phenomenon.

Validating Global Competency Scale for Indian Business and Management Education
Revista Romaneasca pentru Educatie Multidimensionala , 2013,
Abstract: When the organizations started to expand their business across the globe, with the opening up of markets, the issues of international management strategies and competencies of international mangers got more and more attention. Researchers along with the business houses started their quest for identifying, defining and framing a set of competencies necessary for a successful international manager. In this process throughout the years a number of models and construct have been developed to address the issue of competencies required for globalized management era. In the context of management educations the issues global competency development is yet in the stage of infancy, developing very sluggishly, un-professionally and irrelevantly. Considering the state of pseudo showcasing the global competency development practices in the Bschools in India, the authors attempted to develop a scale for facilitating assessment among the students of b-schools for Indian educational set-up. The present attempt has identified the variables from various models and constructs and checked the validity and reliability of the scale proposed.
Competency Based Curriculum in Higher Education: A Necessity Grounded by Globalization
Revista Romaneasca pentru Educatie Multidimensionala , 2011,
Abstract: Ever demanding forces of globalisation have introduced new discourses into curriculum planning in the higher education. In order to sustain in the knowledge based economy and to deal with demand in job market, incorporation of competency based curriculum is emerging as a necessity in higher education sector. In order to develop competency based curriculum in higher education, determination of competencies for each discipline and subsequent development of means of measurement and performance assessment is a must. There are competency based models developed for specific discipline through intense research can serve as a guiding tool for this purpose. In this backdrop the present paper tries to draw an attention to the importance of competency based curriculum and its pros and cons.
Benign prostatic hyperplasia: Is it a growing public health concern for India?
Bid Hemant,Konwar Rituraj,Singh Vishwajeet
Indian Journal of Medical Sciences , 2008,
Association of IL-4 and IL-1RN (receptor antagonist) gene variants and the risk of type 2 diabetes mellitus: A study in the north Indian population
Bid Hemant,Konwar Rituraj,Agrawal C,Banerjee Monisha
Indian Journal of Medical Sciences , 2008,
Abstract: Background: Inflammation is a key event closely associated with the pathophysiology of type 2 diabetes mellitus (T2DM). Association of genetic polymorphisms of inflammatory cytokines with T2DM is largely unknown. Our objective was to investigate the relationship of polymorphism of IL-1RN and IL-4, two important biomarkers of inflammation, with the risk of T2DM. Setting and Design: We recruited 120 clinically diagnosed T2DM patients and 150 normal healthy controls for this study in order to evaluate the nature of polymorphisms of IL-1RN and IL-4. Materials and Methods: Genomic DNA was isolated from the blood of all subjects, and the variable number of tandem repeat (VNTR) polymorphisms of IL-1RN and IL-4 genes was identified by polymerase chain reaction. Statistical Analysis Used: Genotype distribution and allelic frequencies were compared between patients and control group. Means, as well as odds ratios (ORs) with 95% confidence intervals (CI), were calculated using SPSS software (version 11.5). Results: Our study revealed that distribution of both IL-4 and IL-1RN (VNTR) gene polymorphisms were significantly associated with T2DM subjects. We, however, failed to find any association of gene-gene (IL-4 and IL-1RN) interaction with T2DM. Conclusions: Both IL-4 and IL-1RN (VNTR) gene polymorphisms were significantly associated with T2DM subjects. This may suggest that the genetic polymorphisms of IL-4 and IL-1RN genes could serve as susceptibility indicators for T2DM in the Indian population, but the actual mechanism of these associations will require more elaborate investigations. Lack of association of gene-gene (IL-4 and IL-1RN) interaction with T2DM may indicate the independent nature of influence of both these genes on the risk of T2DM.
Vitamin D receptor (FokI, BsmI and TaqI) gene polymorphisms and type 2 diabetes mellitus : A North Indian study
Bid Hemant,Konwar Rituraj,Aggarwal C,Gautam Sunaina
Indian Journal of Medical Sciences , 2009,
Abstract: Background : The vitamin D receptor (VDR) gene is a candidate gene for susceptibility to several diseases. Studies on association between VDR polymorphisms and risk of type 2 diabetes (T2DM) in different ethnic populations are yet inconclusive. Aims : This study was conducted to evaluate association between VDR polymorphisms and genetic susceptibility to T2DM in the north Indian population. Settings and Design : One hundred clinically diagnosed T2DM patients and 160 healthy controls from the north Indian population were recruited for genetic association study. Materials and Methods : Genomic DNA was extracted from blood and genotyped for the single nucleotide polymorphism SNPs of FokI (T/C) [rs2228570], BsmI (A/G) [rs1544410] and TaqI (C/T) [rs731236] by polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) analysis. Statistical Analysis Used : Genotype distribution and allelic frequencies were compared between patients and controls. Mean values and odds ratios (ORs) with 95% confidence interval (CI) were calculated using SPSS software (version 15.0). Results : The genotype distribution, allele and haplotype frequencies of VDR polymorphism did not differ significantly between patients and controls. Mean age and waist-hip ratio of patients were found to be associated with VDR polymorphism. Combination studies showed FFBbtt increased the risk of T2DM in north Indians. Conclusions : Our data suggest that VDR gene polymorphism in combination of genotypes is associated with the risk of T2DM and thus requires further studies as a probable genetic risk marker for T2DM.
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