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Search Results: 1 - 10 of 33 matches for " Kondaveeti Sureshbabu "
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STUDY OF ANTIOXIDANT POTENTIAL IN LEAVES, STEMS, NUTS OF JUGLANS REGIA L.
G Raja, Ivvala Anand Shaker,Inampudi sailaja,R Swaminathan,S Saleem Basha,Kondaveeti Sureshbabu
International Journal of Bioassays , 2012,
Abstract: Natural antioxidants can protect the human body from free radicals and retard the progress of many chronic diseases as well as lipid oxidative rancidity in foods. The role of antioxidants has protected effect against free radical damage that may cause many diseases including cancer. Primary sources of naturally occurring antioxidants are known as whole grains, fruits, and vegetables. Several studies suggest that regular consumption of nuts, mostly walnuts, may have beneficial effects against oxidative stress mediated diseases such as cardiovascular disease and cancer. The role of antioxidants has attracted much interest with respect to their protective effect against free radical damage that may cause many diseases including cancer. Juglans regia L. (walnut) contains antioxidant compounds, which are thought to contribute to their biological properties. Polyphenols, flavonoids and flavonols concentrations and antioxidant activity of Leaves, Stems and Nuts extract of Juglans regia L. as evaluated using DPPH, ABTS, Nitric acid, hydroxyl and superoxide radical scavenging activity, lipid peroxidation and total oxidation activity were determined. The antioxidant activities of Leaves, Stems and Nuts extract of Juglans regia L. were concentration dependent in different experimental models and it was observed that free radicals were scavenged by the test compounds in all the models.
2,2′-[(4-Ethoxyphenyl)methylene]bis(3-hydroxy-5,5-dimethylcyclohex-2-en-1-one)
N. Sureshbabu,V. Sughanya
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812033934
Abstract: In the title compound, C25H32O5, the two cyclohexenone rings have envelope conformations with the C atom bearing two methyl groups as the flap atom in each ring. Relatively strong intramolecular O—H...O hydrogen bonds are observed.
9-(2,4-Dinitrophenyl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione
N. Sureshbabu,V. Sughanya
Acta Crystallographica Section E , 2013, DOI: 10.1107/s1600536813001384
Abstract: In the title compound, C23H24N2O7, the central 4H-pyran ring adopts a flattened boat conformation, whereas both cyclohexenone rings adopt envelope conformations, the C atom bearing the dimethyl substituent being the flap atom in each case. The mean and maximum deviation of the pyran ring are 0.0379 (4) and 0.0605 (3) . The mean plane of the pyran ring and the dinitrobenzene ring make a dihedral angle of 85.88 (2)°.
2,2′-[(3-Bromo-4-hydroxy-5-methoxyphenyl)methylidene]bis(3-hydroxy-5,5-dimethylcyclohex-2-en-1-one)
V. Sughanya,N. Sureshbabu
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812037853
Abstract: In the title compound, C24H29BrO6, the dihedral angle between the cyclohexenone mean planes is 57.63 (2)° while the dihedral angles between the benzene ring and the cyclohexenone mean planes are 58.42 (2) and 69.08 (3)°. The two cyclohexenone rings both show an envelope conformation, with the C atom bearing two methyl groups as the flap atom in each ring. Two intramolecular O—H...O hydrogen bonds occur. In the crystal, molecules are linked via pairs of O—H...O hydrogen bonds, forming inversion dimers.
10-Benzyl-9-(4-ethoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione
V. Sughanya,N. Sureshbabu
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812036094
Abstract: In the title compound, C32H37NO3, the central dihydropyridine ring adopts a nearly planar flattened-boat conformation, whereas both cyclohexenone rings adopt half-chair conformations. The mean and maximum deviations from the mean plane of the dihydropyridine ring are 0.1252 (9) and 0.188 (1) , respectively. The 4-ethoxyphenyl and phenyl rings form dihedral angles of 75.20 (4) and 82.14 (5)° with the dihydropyridine mean plane, respectively.
9-(4-Hydroxy-3,5-dimethoxyphenyl)-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione
V. Sughanya,N. Sureshbabu
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812010410
Abstract: In the title compound, C25H30O6, the two fused cyclohexanone rings have envelope conformations, whereas the central pyran ring is roughly planar [mximum deviation = 0.045 (2) ]. The pyran and benzene rings are almost perpendicular to each other, making a dihedral angle of 86.32 (2)°. In the crystal, molecules are linked via pairs of O—H...O hydrogen bonds, forming inversion dimers.
Aerosol Properties over Ranchi Measured from Aethalometer  [PDF]
Manoj Kumar, Kumari Lipi, S Sureshbabu, N C Mahanti
Atmospheric and Climate Sciences (ACS) , 2011, DOI: 10.4236/acs.2011.13010
Abstract: Continuous and near-real-time measurements of the mass concentration of Aerosol Black Carbon (BC) were carried out 1st to 31st July 2010 of rainy season and compare with data of July-2010 to March-2011 using an Aethalometer (model AE-31 of Magee Scientific, USA). The principle of the Aethalometer is to measure the attenuation of a beam of light transmitted through a filter, while the filter is continuously collecting an aero-sol sample. This measurement is made at successive regular intervals of a time base period has been. the BC mass concentration is estimated by measuring the change in the transmittance of a quartz filter tape, on to which the particles impinge. The instrument was operated at a time base of 5 min, round the clock with a flow rate of 4-liter min–¹, to study the impact of rainy season on black carbon concentrations over a typical urban environment namely Ranchi, India. BC concentrations were high during morning (0600 to 0900 h) and evening hours (1900 to 2300 h) compared to afternoon hours. During early morning hours, high values of BC are attributed to the turbulence set-in by the solar heating which breaks the night-time stable layer and aero-sols in the nocturnal residual layer are mixed up with those near the surface.
Identification, Synthesis, Isolation and Spectral Characterization of Multidrug-Resistant Tuberculosis (MDR-TB) Related Substances  [PDF]
Sureshbabu Jayachandra, Madhuresh Kumar Sethi, Vipin Kumar Kaushik, Vijayakrishna Ravi, Saiprasad Kottolla, Vikas Chandra Dev, Purbita Chakraborty
Green and Sustainable Chemistry (GSC) , 2018, DOI: 10.4236/gsc.2018.82014
Abstract: Several related substances were detected at trace level in (2R)-2,3-dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl] phenoxy] methyl]imidazo[2,
1-b]oxazole drug substance by a newly developed high-performance liquid chromatography method. All related substances were characterized rapidly but some impurities were found to be intermediates. Proposed structures were further confirmed by characterization using NMR, FT-IR, and HRMS techniques. Based on the spectroscopic data; unknown related sub-stances were characterized as 1-(Methylsulfonyl)-4-[4-(trifluoromethoxy) phenoxy]piperidine; 4-{4-[4-(Tri-fluoromethoxy)-phenoxy]piperidin-1-yl}phenol and 4-{4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl}phenyl methane sulfonate; 4-Bromophenyl methane sulfonate, Ethyl 3,6-dihydro-1(2H)-pyridine carboxylate, (2S)-3-(4-Bromophenoxy)-2-hydroxy-2-methylpropyl methane sulfonate, (2S)-3-(4-Bromophenoxy)-2-methylpropane-1,2-diyldimethane-sulfonate, (2S)-2-Methyl-3-(4-{4-[4-(trifluoromethoxy) phenoxy]-piperidin-1-yl} phenoxy)-propane-1,2-diyldimethane sulfonate, (S)-3-(4-Bromophenoxy)-2-methyl-propane-1,2-diol and corresponding Enantiomer, (2R)-2-[(4-Bromo-phenoxy)methyl]-2-methyloxirane and (2R)-2-[(4-bromophenoxy)methyl]-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b][1,3]
oxazole. A possible mechanism for the formation of these related substances is also proposed.
EVALUATION OF GLYCATED ALBUMIN AND DYSLIPIDEMIA IN TYPE-2 DIABETES MELLITUS
Suresh Babu Kondaveeti, Ivvala Anand Shaker, Aravind Kumar R, Hemraz Palwan, Raja G
International Journal of Bioassays , 2012,
Abstract: Diabetic patients with accompanied (but often unnoticed) dyslipidemia are soft targets of cardiovascular deaths. An early intervention to normalize circulating lipids shown to reduce cardiovascular complications and mortality. Now a day’s Glycated albumin (GA) is a routinely used marker for short-term glycemic control. This investigation is an attempt to evaluate the association between GA and various lipid parameters. Venous blood samples collected from 100 type-2 diabetic patients (46 males, 44 females) and serum analyzed for GA, Fasting blood glucose, Total Cholesterol, Triacylglycerols, HDL-C and LDL-C. L/H risk ratio is also calculated. The levels of GA (%) did not differ significantly between males (8.51 ± 1.17) and females (8.24 ± 1.89), whereas male patients had higher mean values of FBG and various lipid parameters than in females. Patients with GA value >17.0 % showed direct and significant correlation with FBG, TC, LDL-C, L/H risk ratio as compared to patients with GA ≤ 17.0%. There was no significant difference in TG, HDL-C between two groups of glycated albumin. These findings indicate that GA is utilized for screening high risk diabetic patients for early diagnosis of dyslipidemia and timely intervention with lipid lowering drugs.
INDIGENOUS EFFECT OF CYNODON DACTYLON IN EXPERIMENTAL INDUCED ULCERS AND GASTRIC SECRETIONS
Kondaveeti Suresh Babu,Ivvala Anand Shaker,Dabburu Kumaraswamy,S.Saleem Basha
International Research Journal of Pharmacy , 2012,
Abstract: Cynodon dactylon is a perinneal grass,the plant is a rich source of metabolites such as proteins,carbohydrates mineral constituents, β-sitosterols, flavinoids, alkaloids, glycosides and triterpenoids the plant has been long used in traditional medicines to treat various alignments it also has antiviral and antimicrobial properties but none has proved its efficacy in evaluating gastro protective activity so we had made an attempt to evaluate the gastroprotective effect of extract of Cynodon dactylon in albino rats. The experiment was set up using male albino wistar rats weighing 150-180gms. These were further divided evenly into different treatment groups. The extract of Cynodon dactylon was investigated for its anti- ulcer activity against pylorus ligation, aspirin induced and ethanol induced gastric ulcer in rats at 100,200, 300mg/kg body weight. Histopathological assessment of rat stomach was carried out. A significant reduction (p<0.01) in ulcer index was seen in Cynodon dactylon extract treated rats of pylorus ligation, aspirin induced and ethanol induced gastric ulcer models. The gastroprotective effect was further confirmed by histopathological examination of rat stomach. Thus the present study concludes the Cynodon dactylon extract having potential gastroprotective effect in the three models tested.
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