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Search Results: 1 - 10 of 2159 matches for " Koichi Murakami "
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Lorentz Symmetry of Supermembrane in Light Cone Gauge Formulation
Kiyoshi Ezawa,Yutaka Matsuo,Koichi Murakami
Physics , 1997, DOI: 10.1143/PTP.98.485
Abstract: We prove the Lorentz symmetry of supermembrane theory in the light cone gauge to complete the program initiated by de Wit, Marquard and Nicolai. We give some comments on extending the formulation to the M(atrix) theory.
C-reactive protein in patients with advanced metastatic renal cell carcinoma: Usefulness in identifying patients most likely to benefit from initial nephrectomy
Ito Hiroki,Shioi Koichi,Murakami Takayuki,Takizawa Akitoshi
BMC Cancer , 2012, DOI: 10.1186/1471-2407-12-337
Abstract: Objective C-reactive protein (CRP) is considered a useful serum marker for patients with RCC. However, its clinical utility in advanced metastatic renal cell carcinoma (AM-RCC), particularly in deciding whether to perform nephrectomy at the onset, is not well studied. Patients and methods We retrospectively evaluated 181 patients with AM-RCC, including 18 patients underwent potentially curative surgery, 111 underwent cytoreductive nephrectomy, and 52 received medical treatment only. CRP cutoff points were determined by receiver operating characteristic (ROC) curve analysis. Kaplan-Meier and Cox regression analyses were used for survival tests. Results ROC analysis suggested that grouping patients according to 3 CRP ranges was a rational model. Patients with highly elevated CRP (≥67.0 mg/L) presented remarkably poor prognosis despite treatment (nephrectomy or medical treatment only). Cox regression models demonstrated that risk factors of overall survival for patients who underwent nephrectomy were the CRP ranges defined in this study (≤18.0 mg/L, >18.0 and <67.0 mg/L, and ≥67.0 mg/L), ECOG PS (0, 1, and ≥2), and number of metastatic organ sites (0–1 and ≥2). The retrospective design is a limitation of this study. Conclusion Our study demonstrated that the serum CRP level is a statistically significant prognostic parameter for patients with AM-RCC. The data also indicated that pretreatment serum CRP level provides useful prognostic information that helps in deciding whether to perform initial nephrectomy for patients with AM-RCC.
MRI-Based Identification of an Appropriate Point of Needle Insertion for Patients with Idiopathic Carpal Tunnel Syndrome to Avoid Median Nerve Injury
Shigeharu Uchiyama,Toshiro Itsubo,Koichi Nakamura,Hironori Murakami
ISRN Orthopedics , 2011, DOI: 10.5402/2011/528147
Development of Cerebellar Neurons and Glias Revealed by in Utero Electroporation: Golgi-Like Labeling of Cerebellar Neurons and Glias
Yoshiaki Kita, Koichi Kawakami, Yoshiko Takahashi, Fujio Murakami
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0070091
Abstract: Cerebellar cortical functions rely on precisely arranged cytoarchitectures composed of several distinct types of neurons and glias. Studies have indicated that cerebellar excitatory and inhibitory neurons have distinct spatial origins, the upper rhombic lip (uRL) and ventricular zone (VZ), respectively, and that different types of neurons have different birthdates. However, the spatiotemporal relationship between uRL/VZ progenitors and their final phenotype remains poorly understood due to technical limitations. To address this issue, we performed in utero electroporation (IUE) of fluorescent protein plasmids using mouse embryos to label uRL/VZ progenitors at specific developmental stages, and observed labeled cells at maturity. To overcome any potential dilution of the plasmids caused by progenitor division, we also utilized constructs that enable permanent labeling of cells. Cerebellar neurons and glias were labeled in a Golgi-like manner enabling ready identification of labeled cells. Five types of cerebellar neurons, namely Purkinje, Golgi, Lugaro and unipolar brush cells, large-diameter deep nuclei (DN) neurons, and DN astrocytes were labeled by conventional plasmids, whereas plasmids that enable permanent labeling additionally labeled stellate, basket, and granule cells as well as three types of glias. IUE allows us to label uRL/VZ progenitors at different developmental stages. We found that the five types of neurons and DN astrocytes were labeled in an IUE stage-dependent manner, while stellate, basket, granule cells and three types of glias were labeled regardless of the IUE stage. Thus, the results indicate the IUE is an efficient method to track the development of cerebellar cells from uRL/VZ progenitors facing the ventricular lumen. They also indicate that while the generation of the five types of neurons by uRL/VZ progenitors is regulated in a time-dependent manner, the progenitor pool retains multipotency throughout embryonic development.
Changes in Joint Gap Balances between Intra- and Postoperation in Total Knee Arthroplasty
Arata Nakajima,Yasuchika Aoki,Masazumi Murakami,Koichi Nakagawa
Advances in Orthopedics , 2014, DOI: 10.1155/2014/790806
Abstract: Achieving correct soft tissue balance and preparing equal and rectangular extension and flexion joint gaps are crucial goals of TKA. Intraoperative gap balances would change postoperatively; however, changes in joint gap balances between pre- and postoperation remain unclear. To explore these changes associated with TKA, we prospectively investigated 21 posterior cruciate ligament retaining TKAs for varus knees. Intraoperative extension gap balance (iEGB) was 2.6 ± 2.0° varus versus postoperative extension gap balance (pEGB) of 0.77 ± 1.8° valgus ( ), while no significant difference between intraoperative flexion gap balance (iFGB) and postoperative flexion gap balance (pFGB) was observed. We also explored correlations between intraoperative and postoperative gap balances but found no significant correlations. These observations indicate that (i) surgeons should avoid excessive release of the medial soft tissue during TKA for varus knees and (ii) intraoperative gap balance may not be necessarily reflected on postoperative gap balance. 1. Introduction Achieving correct soft tissue balance of the knee is fundamental to the success of TKA [1], and an equal joint gap during extension and flexion is a prerequisite for satisfactory soft tissue balance [2–4]. In addition, equalizing the distance from the femoral component to the tibial surface (i.e., the joint gap) throughout the full range of knee motion prevents lift-off of the tibial component and theoretically assists in achieving proper contact pressure and kinematics. Thus, preparing equal and rectangular extension and flexion joint gaps is the most important goal of TKA. Meanwhile, most surgeons agree that accurate ligament balancing of the knee with varus deformity is difficult especially during posterior cruciate ligament retaining (CR)-TKA. The standard procedure for ligament balancing of the medial side of the knees uses subperiosteal release of the medial collateral ligament (MCL) [5–7]. Despite performing such release of MCL, varus balance is likely to remain in most CR-TKAs because posterior cruciate ligament (PCL) is an important component of the medial supporting mechanism of the knee [8]. Recently, Sekiya et al. reported that residual lateral ligamentous laxity immediately after surgery subsequently corrected itself spontaneously in some instances [9]. This finding suggests that some degree of residual lateral laxity, namely, varus balance, may be tolerable for varus knees so long as proper valgus alignment is maintained. However, it has not been explored whether remaining varus balance is
Salmonella in Liquid Eggs and Other Foods in Fukuoka Prefecture, Japan
Koichi Murakami,Tamie Noda,Daisuke Onozuka,Nobuyuki Sera
International Journal of Microbiology , 2013, DOI: 10.1155/2013/463095
Abstract: The study aimed to evaluate the prevalence of Salmonella in retail and wholesale foods in Fukuoka Prefecture, Japan. A total of 2,021 samples collected between 1999 and 2010 were tested using a culture method. Samples consisted of liquid eggs ( ), meat (beef and pork) ( ), offal ( ), processed meats ( ), seafood ( ), processed seafood (dried fish) ( ), vegetables ( ), processed vegetables ( ), fruits ( ), and herbs ( ) from 574 outlets and wholesale agents in 15 areas (five samples were undocumented regarding outlets). Overall, liquid egg showed significantly ( ) higher frequencies of Salmonella contamination (13.3%) than beef (1/423, 0.2%) and pork (3/235, 1.3%). Salmonella enterica subsp. enterica serovar Enteritidis, the most common serovar as a human pathogen, were isolated from two liquid egg samples. No Salmonella were isolated from seafood and vegetable-related samples including seed sprouts ( ). In conclusion, liquid egg is a significant Salmonella vehicle, showing a need to continue the vaccination of chickens to prevent S. Enteritidis contamination in Japanese eggs. Moreover, further study is needed to evaluate Salmonella contamination in seed sprouts with more sampling from retailers there. 1. Introduction The surveillance of Salmonella in retail and wholesale foods is essential for the prevention of nontyphoidal salmonellosis, which is one of the most important problems for public health in the world [1], including Japan [2]. Salmonella frequently enter the food chain, thereby triggering either sporadic cases or outbreaks of human salmonellosis [1]. Livestock and their products are the most significant foods as vehicles of Salmonella [1, 3]. In other foods, such as vegetables [4] and fish [5], Salmonella can also be present naturally and cause human salmonellosis. Recent data on the prevalence of Salmonella in retail and wholesale foods in Fukuoka Prefecture, Japan, are unavailable; therefore, surveillance is needed for reasons of public health. The aim of the present study is to evaluate the prevalence of Salmonella in retail and wholesale foods in Fukuoka Prefecture, Japan. 2. Materials and Methods 2.1. Sampling Area A total of 2,021 samples were collected from Fukuoka Prefecture between May 1999 and June 2010 (Table 1). These samples consisted of liquid eggs ( ), meat (beef and pork) ( ), offal ( ), processed meats ( ), seafood ( ), processed seafood (dried fish) ( ), vegetables ( ), processed vegetables (shop-prepared salad and pickled vegetable) ( ), fruits ( ), and herbs ( ). The samples were collected from 563 retail outlets and 11
Clinical significance of provoked coronary spasm at chronic stage in patients who underwent successful complete coronary revascularization with first-generation drug-eluting stents  [PDF]
Shigenori Ito, Kosuke Nakasuka, Satoru Sekimoto, Kazuyuki Miyata, Masahiko Inomata, Takayuki Yoshida, Nozomu Tamai, Tomoaki Saeki, Shin Suzuki, Yoshimasa Murakami, Akihiro Morino, Yoshiyuki Shimizu, Koichi Sato
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.34A005
Abstract: Background: Provoked spasm might have influence on cardiovascular events even after successful DES implantation. Methods and results: A consecutive 122 patients who underwent first-generation DES (CypherTM, and TaxusTM) implantation and had no residual stenosis at follow-up coronary angiography were included. All patients also underwent acetylcholine provocation test (ACh) at follow-up angiography. Age, sex, coronary risk factors (smoking, hypertension, diabetes mellitus, dyslipidemia), medication (calcium channel blockers, angiotensin receptor blockers, angiotensin converting enzyme inhibitors, nitrates, β blockers, statins), duration from stent implantation to follow-up angiography (15.5 ± 14.5 months), old myocardial infarction, Ach + were included as variables for multivariate analysis for cardiovascular events (angina pectoris without intervention, target lesion revascularization, acute myocardial infarction, definite or probable stent thrombosis, cardiac death, and stroke). ACh provocation test was positive in 64.8%. The following events occurred during a mean follow-up period of 26.9 ± 9.5 months; angina pectoris without intervention in 12, very late stent thrombosis in 1, acute myocardial infarction in 1, sudden death in 1, and stroke in 4. By Adjusted Cox hazard model, age was the independent predictor of future cardiovascular events. ACh was unbalanced data for Cox hazard model, and by logistic regression model, ACh was the strongest predictor. Conclusions: Coronary endothelial dysfunction at chronic stage is the strongest predictor of further prognosis in patients with first-generation DES.
Multi-locus sequence typing of Salmonella enterica subsp. enterica serovar Enteritidis strains in Japan between 1973 and 2004
Tamie Noda, Koichi Murakami, Tetsuo Asai, Yoshiki Etoh, Tomoe Ishihara, Toshiro Kuroki, Kazumi Horikawa, Shuji Fujimoto
Acta Veterinaria Scandinavica , 2011, DOI: 10.1186/1751-0147-53-38
Abstract: Salmonella enterica subsp. enterica serovar Enteritidis (S. Enteritidis) was responsible for a worldwide pandemic during the 1980s and 1990s; however, changes in the dominant lineage before and after this event remain unknown. It is also difficult to explain why multiple clones of S. Enteritidis (defined by phage types, (PTs)) infecting chicken reproductive tissues emerged simultaneously in geographically separate countries during this pandemic. For example, PT 4 emerged in some European countries during the late 1980s, including England and Wales [1], France [2] and Germany [3], while PT 6 dominated Denmark [4]. PT 8, PT 13a and PT 13 were most common in the USA [5] and in Japan, PT 1 and PT 4 were dominant [6]. To understand the simultaneous emergence of this pathogen, it is necessary to deduce whether these multiple lineages co-instantaneously acquired the ability to colonize chicken reproductive tissues or a single clone that possessed this ability evolved into multiple lineages before the pandemic.Multi-locus sequence typing (MLST) can be used to accurately identify bacterial lineages [7,8]. The genetic distance between two strains can be quantitatively estimated as allelic differences in the nucleotide sequences of housekeeping or virulent genes among bacterial strains [8]. MLST data have been used in evolutionary and population analyses that estimate recombination and mutation rates and also in the investigation of evolutionary relationships among bacteria classified within the same genus [8]. Using MLST, our study aimed to determine the lineages of S. Enteritidis before and after the pandemic during the 1980s and/or 1990s in Fukuoka Prefecture, Japan.Salmonella strains used in this study are listed in Table 1. Human strains from individual food-borne disease outbreaks in 1973-1981 were isolated in the Kanagawa Prefectural Institute of Public Health. Other human strains (isolated from individual outbreaks), the liquid egg strain and the eggshell strain were i
Double chambered right ventricle with severe calcification of the tricuspid valve in an elderly woman: a case report
Nozomu Tamai, Shigenori Ito, Kotaro Morimoto, Masahiko Inomata, Takayuki Yoshida, Shin Suzuki, Yoshimasa Murakami, Koichi Sato
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-210
Abstract: We report a rare case of a 71-year-old Japanese woman who presented with chest discomfort, and was found to have a double chambered right ventricle with severe calcification of the tricuspid valve. This abnormality was found by echocardiography, and the diagnosis was confirmed by multislice cardiac computerized tomography, cardiac magnetic resonance imaging, and cardiac catheterization. Our patient rejected surgical repair, and medical therapy with carvedilol was effective to reduce her symptoms.Calcification of the tricuspid valve is extremely rare, and considered to be due to high pressure in the right ventricle. To the best of our knowledge, there are no other reported cases of this combination of double chambered right ventricle and calcification of the tricuspid valve.Double chambered right ventricle (DCRV) is a rare congenital cardiac anomaly in which the right ventricle is divided into two chambers of high pressure proximal and low pressure distal portion, by an anomalous muscle bundle. DCRV is described to be associated with different congenital disorders, most commonly with a membranous or malalignment type ventricular septal defect (VSD). An association with sub-aortic stenosis, pulmonary valve stenosis, atrial septal defect, double outlet right ventricle, and tetralogy of Fallot has also been reported [1]. Most patients with DCRV are diagnosed and repaired in childhood or adolescence; in contrast, the diagnosis is sometimes difficult in adults [2,3].Calcification of the tricuspid valve is rare, and very few cases have been reported [4-7]. The mechanism of calcification of the tricuspid valve is considered to be due to the high pressure or volume overload of the right ventricle associated with congenital disorder.A 71-year-old Japanese woman was referred to our institution for further evaluation of chest discomfort, heavy dizziness and nausea after the use of nitroglycerin prescribed by a general practitioner.On physical examination, cardiac auscultation r
Dynamic Effect of Low-Cost Entry on the Conduct Parameter: An Early-Stage Analysis of Southwest Airlines and America West Airlines  [PDF]
Hideki Murakami
Modern Economy (ME) , 2013, DOI: 10.4236/me.2013.44032

The purpose of this research is to investigate the dynamic changes in the competition between air carriers by applying a revised conduct parameter method. We examine the cases of Southwest Airlines and America West Airlines due to the availability of data. Our interests are in what fashion a low-cost carrier entered the market, how the rival reacted, and whether the fashions of competition between two types of air carrier remained stable as time passed. Our empirical results show that the fashions of competition fell between Cournot and “P = MC” competition, and competitive fashions were sometimes stable but sometimes not.

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