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Search Results: 1 - 10 of 4593 matches for " Klaus Heese "
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MAGNITUDE OF THYMINE IN DIFFERENT FRAMES OF MESSENGER RNAs
Rajasekaran E.,Asha Jacob,Klaus Heese
International Journal of Bioinformatics Research , 2012,
Abstract: Thymine is the one and only base transcribed into uracil during production of proteins. Thymine in DNA and uracil in mRNA plays a major role in producing proteins with appropriate carbon content for stability and activity. Thymine distribution is different frames of coding nucleic acids are investigated statistically. The results confirm that frame 1 supposed to have definite thymine content. Frame 3 prefers to have least thymine content. Frames 4 & 5 maintain some degree of thymine while 2 & 6 have a variable fraction of thymine
Acute-Phase Serum Amyloid A as a Marker of Insulin Resistance in Mice
Ludger Scheja,Barbara Heese,Heike Zitzer,Mervyn D. Michael,Angela M. Siesky,Heike Pospisil,Ulrike Beisiegel,Klaus Seedorf
Experimental Diabetes Research , 2008, DOI: 10.1155/2008/230837
Abstract: Acute-phase serum amyloid A (A-SAA) was shown recently to correlate with obesity and insulin resistance in humans. However, the mechanisms linking obesity-associated inflammation and elevated plasma A-SAA to insulin resistance are poorly understood. Using high-fat diet- (HFD-) fed mice, we found that plasma A-SAA was increased early upon HFD feeding and was tightly associated with systemic insulin resistance. Plasma A-SAA elevation was due to induction of Saa1 and Saa2 expression in liver but not in adipose tissue. In adipose tissue Saa3 was the predominant isoform and the earliest inflammatory marker induced, suggesting it is important for initiation of adipose tissue inflammation. To assess the potential impact of A-SAA on adipose tissue insulin resistance, we treated 3T3-L1 adipocytes with recombinant A-SAA. Intriguingly, physiological levels of A-SAA caused alterations in gene expression closely resembling those observed in HFD-fed mice. Proinflammatory genes (Ccl2, Saa3) were induced while genes critical for insulin sensitivity (Irs1, Adipoq, Glut4) were down-regulated. Our data identify HFD-fed mice as a suitable model to study A-SAA as a biomarker and a novel possible mediator of insulin resistance.
Entropic uncertainty bound for open pointer-based simultaneous measurements of conjugate observables
Raoul Heese,Matthias Freyberger
Mathematics , 2015, DOI: 10.1088/1751-8113/48/13/135304
Abstract: We discuss the information entropy for a general open pointer-based simultaneous measurement and show how it is bound from below. This entropic uncertainty bound is a direct consequence of the structure of the entropy and can be obtained from the formal solution of the measurement dynamics. Furthermore, the structural properties of the entropy allow us to give an intuitive interpretation of the noisy influence of the pointers and the environmental heat bath on the measurement results.
Essentials of a Bariatric Patient Handling Program
Marylou Muir,Gail Archer-Heese
Online Journal of Issues in Nursing , 2009,
Abstract: There is a noticeable increase in the number of bariatric admissions to healthcare facilities. This trend presents a challenge to healthcare providers and facilities striving to provide dignified care that is effective and safe both for the patient and the provider. Many bariatric patients, due to their size and difficulty with mobility, require assistance with numerous activities of daily living. The more mobility-dependent the patient is, the greater the risk for injury for those providing the care. The additional myriad of bariatric patients' co-morbidities makes these patients especially vulnerable for health complications during their hospital stay. The authors of this article provide definitions related to bariatrics and describe specific health concerns of bariatric patients. They also discuss the risks of injury for providers caring for bariatric patients, explain the components of a bariatric safe patient handling program, and conclude with a discussion of current issues related to the care of bariatric patients.
Ceilometer lidar comparison: backscatter coefficient retrieval and signal-to-noise ratio determination
B. Heese, H. Flentje, D. Althausen, A. Ansmann,S. Frey
Atmospheric Measurement Techniques (AMT) & Discussions (AMTD) , 2010,
Abstract: The potential of a new generation of ceilometer instruments for aerosol monitoring has been studied in the Ceilometer Lidar Comparison (CLIC) study. The used ceilometer was developed by Jenoptik, Germany, and is designed to find both thin cirrus clouds at tropopause level and aerosol layers at close ranges during day and night-time. The comparison study was performed to determine up to which altitude the ceilometers are capable to deliver particle backscatter coefficient profiles. For this, the derived ceilometer profiles are compared to simultaneously measured lidar profiles at the same wavelength. The lidar used for the comparison was the multi-wavelengths Raman lidar PollyXT. To demonstrate the capabilities and limits of ceilometers for the derivation of particle backscatter coefficient profiles from their measurements two examples of the comparison results are shown. Two cases, a daytime case with high background noise and a less noisy night-time case, are chosen. In both cases the ceilometer profiles compare well with the lidar profiles in atmospheric structures like aerosol layers or the boundary layer top height. However, the determination of the correct magnitude of the particle backscatter coefficient needs a calibration of the ceilometer data with an independent measurement of the aerosol optical depth by a sun photometer. To characterizes the ceilometers signal performance with increasing altitude a comprehensive signal-to-noise ratio study was performed. During daytime the signal-to-noise ratio is higher than 1 up to 4–5 km depending on the aerosol content. In our night-time case the SNR is higher than 1 even up to 8.5 km, so that also aerosol layers in the upper troposphere had been detected by the ceilometer.
Description of Meloidoderita salina sp. n. (Nematoda, Sphaeronematidae) from a micro-tidal salt marsh at Mont-Saint-Michel Bay in France
Samad Ashrafi,Didier Mugniery,Evelyn van Heese,Adriaan van Aelst
ZooKeys , 2012, DOI: 10.3897/zookeys.249.4138
Abstract: Meloidoderita salina sp. n. is described and illustrated from the halophytic plant Atriplex portulacoides L. (sea purslane) growing in a micro-tidal salt marsh in the Mont-Saint-Michel Bay in France. This new species is the first member of Meloidoderita Poghossian, 1966 collected from a saline environment, and is characterized by the following features: sedentary mature femalesa small swollen body with a clear posterior protuberance; slightly dorsally curved stylet, 19.9 μm long, with posteriorly sloping knobs; neck region irregular in shape and twisted; well developed secretory-excretory (S–E) pore, with markedly sclerotized S-E duct running posteriorly; prominent uterus bordered by a thick hyaline wall and filled with eggs. The adult female transforms into a cystoid. Eggs are deposited in both egg-mass and cystoid. Cystoids of Meloidoderita salina sp. n. display a unique sub-cuticular hexagonal beaded pattern.Male without stylet, pharyngeal region degenerated, S-E duct prominent, deirids small, developed testis 97.5 μm long, spicules 18.4 μm long, cloacal opening ventrally protruded, small phasmids posterior to cloaca opening and situated at 5.9 (3.2–7.7) μm from tail end, and conical tail ending in a rounded terminus marked with one (rarely two) ventrally positioned mucro. Additionally, some young males of the new species were observed enveloped in the last J2 cuticle. Second-stage juvenile body 470 μm long, with a 16.4 μm long stylet, prominent rounded knobs set off from the shaft, hemizonid anterior and adjacent to S-E pore, small deirids located just above S-E pore level, genital primordium located at 68–77% of body length, phasmids small and located at about 19 μm from tail tip, and tail 38.7 μm long, tapering to finely pointed terminus with a finger-like projection. Phylogenetic analyses based on the nearly full length small subunit ribosomal DNA sequences of Meloidoderita salina sp. n. revealed a close relationships of the new species with Sphaeronema alni Turkina & Chizhov, 1986 and placed these two species sister to the rest of Criconematina.
On the species status of the root-knot nematode Meloidogyne mayaguensis Rammah & Hirschmann, 1988
Gerrit Karssen,Jinling Liao,Zhuo Kan,Evelyn van Heese
ZooKeys , 2012, DOI: 10.3897/zookeys.181.2787
Abstract: Holo- and paratypes of the root-knot nematodes Meloidogyne mayaguensis Rammah & Hirschmann, 1988 and M. enterolobii Yang & Eisenback, 1983 were morphometrically and morphologically compared. All observed female, male and second-stage juvenile morphometrical and morphological characters are identical for the two studied species. Additionally, contradictions between the original species descriptions were unravelled.The present study of holo- and paratypes confirms the taxonomical status of Meloidogyne mayaguensis as a junior synonym for M. enterolobii.
Ceilometer-lidar inter-comparison: backscatter coefficient retrieval and signal-to-noise ratio determination
B. Heese,H. Flentje,D. Althausen,A. Ansmann
Atmospheric Measurement Techniques Discussions , 2010, DOI: 10.5194/amtd-3-3907-2010
Abstract: The potential of a new generation of ceilometer instruments for aerosol monitoring has been studied in the Ceilometer-Lidar Inter- Comparison (CLIC) study. The ceilometer is of type CHM15k from Jenoptik, Germany, which uses a solid state laser at the wavelength of 1064 nm and an avalanche photodiode for photon counting detection. The German Meteorological Service is in progress of setting up a ceilometer network for aerosol monitoring in Germany. The intercomparison study was performed to determine whether the ceilometers are capable to deliver quality assured particle backscatter coefficient profiles. For this, the derived ceilometer profiles were compared to simultaneously measured lidar profiles at the same wavelength. The lidar used for this intercomparison was IfTs multi-wavelengths Raman lidar PollyXT. During the EARLINET lidar intercomparison campaign EARLI 09 in Leipzig, Germany, a new type of the Jenoptik ceilometer, the CHM15k-X, took part. This new ceilometer has a new optical setup resulting in a complete overlap at 150 m. The derived particle backscatter profiles were compared to profiles derived from PollyXTs measurements, too. The elastic daytime particle backscatter profiles as well as the less noisy night-time Raman particle backscatter profiles compare well with the ceilometers profiles in atmospheric structures like aerosol layers or the boundary layer top height. The calibration of the ceilometer profiles by an independent measurement of the aerosol optical depth (AOD) by a sun photometer is necessary to determine the correct magnitude of the particle backscatter coefficient profiles. A comprehensive signal-to-noise ratio study was carried out to characterize the ceilometers signal performance with increasing altitude.
Aerosol profiling using the ceilometer network of the German Meteorological Service
H. Flentje,B. Heese,J. Reichardt,W. Thomas
Atmospheric Measurement Techniques Discussions , 2010, DOI: 10.5194/amtd-3-3643-2010
Abstract: The German Meteorological Service (DWD) operates about 52 lidar ceilometers within its synoptic observations network, covering Germany. These affordable low-power lidar systems provide spatially and temporally high resolved aerosol backscatter profiles which can operationally provide quasi 3-D distributions of particle backscatter intensity. Intentionally designed for cloud height detection, recent significant improvements allow following the development of the boundary layer and to detect denser particle plumes in the free tropospere like volcanic ash, Saharan dust or fire smoke. Thus the network builds a powerful aerosol plume alerting and tracking system. If auxiliary aerosol information is available, the particle backscatter coefficient, the extinction coefficient and even particle mass concentrations may be estimated, with however large uncertainties. Therefore, large synergistic benefit is achieved if the ceilometers are linked to existing lidar networks like EARLINET or integrated into WMO's envisioined Global Aerosol Lidar Observation Network GALION. To this end, we demonstrate the potential and limitations of ceilometer networks by means of three representative aerosol episodes over Europe, namely Sahara dust, Mediterranean fire smoke and, more detailed, the Icelandic Eyjafjoll volcano eruption from mid April 2010 onwards. The DWD (Jenoptik CHM15k) lidar ceilometer network tracked the Eyjafjoll ash layers over Germany and roughly estimated peak extinction coefficients and mass concentrations on 17 April of 4–6(± 2) 10-4 m 1 and 500–750(± 300) μg/m 3, respectively, based on co-located aerosol optical depth, nephelometer (scattering coefficient) and particle mass concentration measurements. Though large, the uncertainties are small enough to let the network suit for example as aviation advisory tool, indicating whether the legal flight ban threshold of presently 2 mg/m3 is imminent to be exceeded.
An Enduring Concept for Security Council Reform  [PDF]
Klaus Schlichtmann
Beijing Law Review (BLR) , 2011, DOI: 10.4236/blr.2011.22010
Abstract: UN Security Council reform has been lingering over the years, since it was first seriously considered in the 1990s, after the collapse of the Soviet Union. This paper argues that enlarging the Security Council by adding new permanent and non-permanent members, while many of the Charter provisions vital for the maintenance of international peace and security and disarmament are not in effect, would be counterproductive. Instead, the composition of the Council should be reshuffled and expanded by giving a seat to a prominent member of the Global South, i.e. India, and replacing the seats of France and Britain with a single European representation. While there would be no increase or change in the number of permanent and non-permanent members, the result will be a dramatic increase in the numbers of people represented by the Permanent Five, which then will, in effect, comprise half of the world’s population projected for 2012. The underlying logic is that increasing the number of permanent members (P5) would make the Security Council not only less effective, but also prevent the realization of a fundamental purpose of the United Nations, i.e. the transition from an armed to an unarmed peace. By maintaining the number 5, the effective operation of the consensus principle required for the maintenance of international peace and security during the transition is ensured. It is maintained that the changes proposed in this paper may be regarded as “purely procedural” under Article 27 paragraph 2 of the Charter. It will be seen, however, that to trigger the process of the transition, UN Member states (other than the P5, who bear responsibility under the Charter to guarantee safe passage during the transition) must begin, one by one, to delegate “Security Sovereignty” to the Council.
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