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Search Results: 1 - 10 of 139174 matches for " Kishore K "
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Trends in VLSI Technology - Rural Applications Perspective
Kishore K
IETE Technical Review , 2007,
Abstract: VLSI Technology has advanced rapidly since late 90s. Low cost, high performance Chips designed and fabricated made strong impact in systems development and resulted in applications to diversified fields like computers, communications, entertainment electronics, medicine, and rural necessities. Spreading of Internet globally, making this world as a ′global village" and rapid strides in mobile communications have a direct bearing on the progress made in VLSI technology. Research work is being done to further develop the technology in new dimensions like Silicon Photonics, Organic semi-conductors, Flexible displays etc. These developments take the technology further close to rural applications and can result in significant improvement in the quality of life in villages. Fibre optic connectivity, hosting of portals with useful information to rural folk, e-governance, energy conservation, wireless sensor networks, Telephone-TV can improve the standard of living in rural areas significantly. VLSI technology directly or indirectly is playing a vital role in this direction. This paper reviews various developments taking place in the technology, research work being done in this area, new devices and systems being developed and their applications. The application of the technology and systems developed for rural areas is also discussed. The projects implemented and possible developments to improve quality of life in rural areas is discussed. With the rapid strides being made in silicon device technology, efficient, low cost devices with high performance are being manufactured. The chip design methods, making use of the software tools are producing hardware for various applications like computers, communications, defence, household appliances, commercial toys etc. These developments are also making inroads into rural areas and changing the technological applications scenario there. Hosting of websites / portals with information useful to rural areas is proving to be a boon, for which the VLSI technology is contributing significantly.
The Heart of Structural Development: The Functional Basis of the Location and Morphology of the Human Vascular Pump
Kishore K
Journal of Postgraduate Medicine , 2003,
Molecular Profiling of Drug Resistant Isolates of Mycobacterium tuberculosis in North India  [PDF]
Dinesh K. Tripath, Kanchan Srivastava, Surya Kant, Kishore K. Srivastava
Advances in Microbiology (AiM) , 2012, DOI: 10.4236/aim.2012.23038
Abstract: Multidrug-resistant tuberculosis (MDR-TB) is a major public health problem because treatment is complicated, cure rates are well below those for drug susceptible tuberculosis (TB), and patients may remain infectious for months or years despite receiving the best available therapy. To gain a better understanding of MDR-TB, we characterized isolates recovered from 69 patients with MDR-TB, by use of IS6110 restriction fragment-length polymorphism (RFLP) analysis; spacer oligonucleotide genotyping (i.e. spoligotyping). Clinical isolates from patients with tuberculosis have been considered to contain clonally expanded Mycobacterium tuberculosis (MTB) strain. Over the years, the identification method based on IS6110 insertion sequences has been established as the standard for typing strains of MTB. IS6110 RFLP fingerprinting is very convincing when it is applied to classify MTB isolates harboring a large number of IS6110 in their chromosomes. Therefore, in the present study we have characterized the isolates from the patients suffering from MDR TB, on the basis of conserved Variable Number Tandem Repeats (VNTR), Direct Repeats (DR) and Insertion Sequences (IS) IS6110 elements. The polymorphic data showed significant level of dissimilarities among all the MDR isolates of MTB. Comparative studies with the DR and VNTR data substantiate that polymorphism occur among MDR-TB cases as shown by the number of repeats present in different clinical isolates.
Recognizing scientific excellence in the biology of cell adhesion
Kishore K Wary
Cell Communication and Signaling , 2005, DOI: 10.1186/1478-811x-3-7
Abstract: Well, why does our skin look so smooth on the surface? How do skin cells adhere to each other and the underlying connective tissue to resist wound and bruise? How do two 'unlike' or 'like' cells live side-by-side? How are muscles and tendons glued to the bones? How do endothelial and epithelial cells are separated from each other? What mechanisms divide astrocytes, neurons, and the endothelial cells that make up the neurovascular unit? The answer is "cell adhesion", which is because of the characteristic properties of proteins and molecules that act like 'glue' or 'sticky molecules'. If cells or tissues do not hold each other, like in blistering skin in which something as gentle as a human touch can cause the skin to blister and peel away, inviting fatal infection and wound that may never heal. Suffice to say, the chances of survival will be somewhat diminished.In the late 1970's two ideas were put forward. First, the chemoaffinity hypothesis proposed that cell-cell contacts are mediated by unique set of cell adhesion molecules presented by adjacent cells. Second, adhesion molecules are limited, but their affinity could switch from low to high and vice versa. Soon afterwards, several important cell adhesion molecules were discovered and described including the cadherins, neuronal cell adhesion molecules (NCAM), extracellular matrix (ECM) molecules, proteoglycans, the immunoglobulin cell adhesion molecules, junctional adhesion molecules (JAMs), connexins, and selectins. Those ideas are very much alive and many cell adhesion molecules discovered recently are being tested with stringent criteria with better technologies today.There may not be a unifying answer to that question. In one of the landmark articles, Dr. Masatoshi Takeichi [Fig. 1A] described calcium-dependent and -independent mechanisms of cell adhesion [1]. Cell-aggregation assays of disaggregated tissue and cells provided indication that the cadherins promote 'homophilic' interactions, a process that requi
Signaling through Raf-1 in the Neovasculature and Target Validation by Nanoparticles
Kishore K Wary
Molecular Cancer , 2003, DOI: 10.1186/1476-4598-2-27
Abstract: For tumors to survive, grow and disseminate, they must be able to secrete critical growth factors and cytokines. It is estimated that 15 to 20 different cytokines are secreted by various tumors. These cytokines determine the characteristics and behaviors of many solid tumors. Some of these cytokines can positively influence neovascularization or angiogenesis, and others negatively regulate this process. It is thought that an "angiogenic switch", or the balance between positive and negative regulators, regulates the process of angiogenesis. The neovascularization process ultimately serves as a conduit to bring in nutrients that promote growth and metastasis [1]. Thus, the angiogenic switch also determines tumor cell growth. Many of these cytokines are also used under normal physiological conditions in various cells and tissues; therefore, direct interference with these cytokines is not a viable option. It has been recently shown that signaling events mediated by bFGF in endothelial cells targets Raf-1 to the mitochondria, which protects these cells from apoptosis [2]. This provides a mechanism that effectively explains why targeting the tumor neovasculature with a mutant Raf-1 gene exerts anti-angiogenic effects [3].A number of cytokines and growth factor polypeptides have been shown to act as survival factors during angiogenesis, including the acidic and basic fibroblast growth factors (FGFs) and vascular endothelial growth factor (VEGF). Basic FGF (bFGF) and VEGF are two of the cytokines that have been most widely studied, because of their ability to induce many physiological responses, including survival and tumor growth. Both in vitro and in vivo studies suggest that these mediators play a role in angiogenesis. These studies showed that bFGF and VEGF induce mitogenesis and capillary morphogenesis. Furthermore, these factors and their receptors are up-regulated under ischemic conditions in vivo, and administration of these proteins in vivo enhances capillary morph
A new vision on audition: a comparative study of the apparatus concerned with equilibrium and hearing.
Shyam Kishore K
Journal of Postgraduate Medicine , 2003,
A Modified Epidemic Chain Binomial Model  [PDF]
Dilip C. Nath, Kishore K. Das, Tandrima Chakraborty
Open Journal of Statistics (OJS) , 2016, DOI: 10.4236/ojs.2016.61001

Discrete epidemic models are applied to describe the physical phenomena of spreading infectious diseases in a household. In this paper, an attempt has been made to develop a modified epidemic chain model by assuming a beta distribution of third kind for the probability of being infected by contact with a given infective from the same household with closed population. This paper emphasizes mainly on developing the probabilities of all possible epidemic chains with one introductory case for three, four and five member household. The key phenomenon towards developing this paper is to provide an alternative model of chain binomial model.

A Modified Epidemic Chain Binomial Model (MECBM) and Its 2,3-Introductory Probabilities  [PDF]
Dilip C. Nath, Kishore K. Das, Tandrima Chakraborty
Open Journal of Statistics (OJS) , 2017, DOI: 10.4236/ojs.2017.72018
Abstract: Through the ages, human life and happiness are affected much by wide spread diseases, an unpredictable phenomenon. And infectious disease spread is one of the most unsolvable problems. How infection evolves, how it spreads from person to person and mainly which pattern it follows are some questions which are always unanswerable. Out of many techniques, discrete epidemic models like the chain binomial model are ones which are applied to describe the physical phenomena of spreading infectious diseases in a household. In this paper, an attempt has been made to develop a modified epidemic chain model by assuming a beta distribution of third kind for the probability of being infected by contact with a given infection from the same household with closed population. This paper emphasized mainly on developing the probabilities of all possible epidemic chains with two introductory cases for three-, four- and five-member household and three introductory cases for four- and five-member household. The key phenomenon towards developing this paper was to provide an extension of the modified chain binomial model and its possible probabilities.
Investigation Into the Conductance, Micellization and Dissociation Behaviour of Terbium Caprylate and Caprate in 60/40 Benzene-methanol Mixture (v/v)
Kishore,Kamal; Upadhyaya,S. K.;
Portugaliae Electrochimica Acta , 2010,
Abstract: conductance measurements were employed to determine the critical micellar concentration, cmc, limiting molar conductance at infinite dilution, degree of dissociation and dissociation constant of terbium caprylate and caprate in 60/40 benzene-methanol (v/v). the results have shown that these soaps behave as a weak electrolyte in dilute solutions and debye-hückel-onsager’s equation is not applicable to these soap solutions. the thermodynamic parameters indicate that the micellization process is favoured over the dissociation process.
On the consistency of limitation methods for (N,pn) summable sequences
Nand Kishore,U. K. Misra
International Journal of Mathematics and Mathematical Sciences , 1981, DOI: 10.1155/s0161171281000112
Abstract: Two limitation methods, A and B, are said to be consistent for a class b of sequences, iff, every sequence belonging to b is limitable both by A and B and that the A-limit equals the B-limit. Any two regular limitation methods are consistent for the class-c of convergent sequences. However, this is not true in general and in fact, corresponding to every bounded non-convergent sequence it is possible to determine two T-matrices such that they limit the sequence to two different values. In this paper, we establish the necessary and sufficient conditions for the consistency of two limitation methods, for (N,pn) summable sequences.
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