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Search Results: 1 - 10 of 1931 matches for " Kimberley Edwards "
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Joint disease mapping using six cancers in the Yorkshire region of England
Amy Downing, David Forman, Mark S Gilthorpe, Kimberley L Edwards, Samuel OM Manda
International Journal of Health Geographics , 2008, DOI: 10.1186/1476-072x-7-41
Abstract: Data on the incidence of oesophagus, stomach, pancreas, lung, kidney, and bladder cancers between 1983 and 2003 were extracted from the Northern & Yorkshire Cancer Registry database for the 532 electoral wards in the Yorkshire region. Using postcode of residence, each case was assigned an area-based measure of SEB using the Townsend index. Standardised incidence ratios (SIRs) were calculated for each cancer site and their correlations investigated. The joint analysis of the spatial variation in incidence used a Bayesian shared-component model. Three components were included to represent differences in smoking (for all six sites), bodyweight/obesity (for oesophagus, pancreas and kidney cancers) and diet/alcohol consumption (for oesophagus and stomach cancers).The incidence of cancers of the oesophagus, pancreas, kidney, and bladder was relatively evenly distributed across the region. The incidence of stomach and lung cancers was more clustered around the urban areas in the south of the region, and these two cancers were significantly associated with higher levels of area deprivation. The incidence of lung cancer was most impacted by adjustment for SEB, with the rural/urban split becoming less apparent. The component representing smoking had a larger effect on cancer incidence in the eastern part of the region. The effects of the other two components were small and disappeared after adjustment for SEB.This study demonstrates the feasibility of joint disease modelling using data from six cancer sites. Incidence estimates are more precise than those obtained without smoothing. This methodology may be an important tool to help authorities evaluate healthcare system performance and the impact of policies.Mapping of the geographical distribution of cancer incidence, survival, or mortality rates can help us understand spatial patterns of disease and identify differences in disease burden across an area. These maps can be used by those involved in the planning of services or
Advances in Microsimulation Modeling of Population Health Determinants, Diseases, and Outcomes
Jacek A. Kopec,Kimberley Edwards,Douglas G. Manuel,Carolyn M. Rutter
Epidemiology Research International , 2012, DOI: 10.1155/2012/584739
Abstract:
Advances in Microsimulation Modeling of Population Health Determinants, Diseases, and Outcomes
Jacek A. Kopec,Kimberley Edwards,Douglas G. Manuel,Carolyn M. Rutter
Epidemiology Research International , 2012, DOI: 10.1155/2012/584739
Abstract:
Advances Towards Personalised Medicine: What is the Cost of Knowing your Genome?
Kimberley Byron
Opticon1826 , 2011, DOI: 10.5334/opt.111110
Abstract: Since the completion of the Human Genome Project (HGP) in 2003, scientists have been working towards making whole genome sequencing a useful clinical diagnostic tool. The aim of many of the big biotechnology companies is to make this technique affordable and accessible so that it can be routinely used to diagnose rare genetic disorders and tailor medical treatment to an individual’s genetic code – a practice called personalised medicine.
écriture et plurilinguisme dans _Traversée de la mangrove_
Kimberley Bruno
Voix Plurielles , 2011,
Abstract: L’hétérolinguisme dans le texte littéraire et le fait plurilinguistique sont, non seulement des caractéristiques fondamentales des écritures francophones, mais constituent des paradigmes importants pour la description des effets de langue qui fondent ces écritures. Les réflexions proposées ici visent à étudier les modalités d’inscription et la signification du fait plurilinguistique dans le roman Traversée de la mangrove de Maryse Condé.
Significant contributing causes of cancer deaths among Hispanics in Colorado, USA, 1983-1992
Sweitzer, Kimberley;Stallones, Lorann;
Cadernos de Saúde Pública , 1998, DOI: 10.1590/S0102-311X1998000700020
Abstract: cancer deaths in the state of colorado, u.s.a., totaled 53,921 between 1983 and 1992. death certificates for this period were used to evaluate hispanic cancer deaths by contributing causes of death and primary occupation of the decedent. the relative risks for diabetes and liver disease as contributing causes of death were significantly higher among hispanics when compared to non-hispanics who had also died of cancer (rr for diabetes = 1.90; 95% c.i. (1.64,2.19) and rr for liver disease = 1.44; 95% c.i. (1.23,1.68)). hispanics who had died of cancer were significantly less likely to have drug abuse as a contributing cause of death when compared to non-hispanics (rr for drug abuse = 0.69; 95% c.i. (0.52,0.91)). laborers, service workers, and clerical workers who were hispanic, were significantly more likely to die of cancer with either diabetes or liver disease as a contributing cause of death than were non-hispanics in the same occupational category (p<0.05). chronic diseases, such as diabetes and liver disease, may be reducing the survivability of cancer among hispanics.
Significant contributing causes of cancer deaths among Hispanics in Colorado, USA, 1983-1992
Sweitzer Kimberley,Stallones Lorann
Cadernos de Saúde Pública , 1998,
Abstract: Cancer deaths in the state of Colorado, U.S.A., totaled 53,921 between 1983 and 1992. Death certificates for this period were used to evaluate Hispanic cancer deaths by contributing causes of death and primary occupation of the decedent. The relative risks for diabetes and liver disease as contributing causes of death were significantly higher among Hispanics when compared to non-Hispanics who had also died of cancer (RR for diabetes = 1.90; 95% C.I. (1.64,2.19) and RR for liver disease = 1.44; 95% C.I. (1.23,1.68)). Hispanics who had died of cancer were significantly less likely to have drug abuse as a contributing cause of death when compared to non-Hispanics (RR for drug abuse = 0.69; 95% C.I. (0.52,0.91)). Laborers, service workers, and clerical workers who were Hispanic, were significantly more likely to die of cancer with either diabetes or liver disease as a contributing cause of death than were non-Hispanics in the same occupational category (p<0.05). Chronic diseases, such as diabetes and liver disease, may be reducing the survivability of cancer among Hispanics.
Battling Phages: How Bacteria Defend against Viral Attack
Kimberley D. Seed
PLOS Pathogens , 2015, DOI: 10.1371/journal.ppat.1004847
Abstract:
Predicting the Outcome of Nerve Conduction Studies in Patients with Suspected Carpal Tunnel Syndrome: Using an Existing Carpal Tunnel Assessment Tool  [PDF]
Carl Edwards, Ian Frampton
Open Journal of Therapy and Rehabilitation (OJTR) , 2014, DOI: 10.4236/ojtr.2014.22010
Abstract: This service evaluation and pilot study was designed to establish whether a clinical questionnaire could be incorporated within our Secondary Care Carpal Tunnel Service. The purpose of the questionnaire is to predict the positive and negative results of Nerve Conduction Studies (NCS) in those patients with suspected Carpal Tunnel Syndrome. The hand specialist, preceding NCS administered the questionnaire; it was then scored at a later date. Results showed a sensitivity of 86% and specificity of 84% referring to the ability to predict a positive NCS when using a predetermined cut-off score. When analysed with Receiver Operating Characteristics, a threshold score could be determined in order to obtain 100% sensitivity/specificity. This questionnaire can be used as a useful adjunct to assessment of those presenting with suspected Carpal Tunnel Syndrome. Using the questionnaire to identify those patients scoring outside a predetermined threshold range would reduce the need for NCS by nearly 50%, with significant cost and clinical practice implications.
Men, appearance, and cosmetic surgery: The role of confidence, self-esteem, and comfort with the body
Rosemary Ricciardelli,Kimberley Ann Clow
The Canadian Journal of Sociology , 2009,
Abstract: This paper situates male perceptions of the body within Bourdieu’s theories of human practice. Recent research (Bordo 1999; Featherstone 1991; Giddens 1991; Gill, Henwood, and McLean 2005) has suggested that perceptions of the body are important to men’s sense of confidence and that men see the body as a vehicle for personal improvement. To build on this research, an online survey investigated Canadian men’s perspectives on their appearance and their attitudes toward cosmetic surgery. A two-component approach to self-esteem was used, where self-confidence (the positive aspect) and self-deprecation (the negative aspect) were seen as independent but related concepts that underlie one’s feelings of self-worth. Self-deprecation, self-confidence, and comfort with one’s body uniquely predicted different aspects of men’s experiences, including attitudes about body shape, perceptions of others, pressures to lose weight, and perspectives regarding cosmetic surgery. For example, participants who were more comfortable with their bodies and lower in self-deprecation were happier with their current body shape and features, whereas participants who were less comfortable with their bodies and lower in confidence put more pressure on themselves to lose weight. In addition, lower confidence significantly predicted willingness to undergo cosmetic surgery.
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