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OALib Journal期刊

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PHYTOCHEMICAL SCREENING AND THE EVALUATION OF THE ANTIOXIDANT, ANTIMICROBIAL AND ANALGESIC PROPERTIES OF THE PLANT IPOMOEA MAURITANA (FAMILY: CONVOVULACEAE)
Monjur-Al-Hossain A.S.M.,Mahadhi Hasan Md.,Khushi shamsunnahar,Dey Avijit
International Research Journal of Pharmacy , 2013,
Abstract: Ipomoea mauritiana is an important medicinal plant having widespread application in a variety of disorders. The aim of this study was the phytochemical investigation and evaluation of the anti-oxidant, anti-microbial and analgesic activities of the whole plant Ipomoea mauritiana. Phytochemical screening of the ethanolic extract of Ipomoea mauritiana ensured the presence of Alkaloids, Tannins, Steroids, Gums, Glycosides, Carbohydrate and Saponins. The anti-oxidant activity was measured by DPPH free radical scavenging activity (IC50 = 164 μg/ml). The crude ethanolic extract did not reveal any significant anti-microbial activity. The crude ethanolic extract of the tubers of Ipomoea mauritiana exhibited significant analgesic activity at a dose of 250 mg/kg and 500 mg/kg with 71.15% and 80.77 % inhibition of writhing respectively.
FACEBOOK STATUS UPDATES: A SPEECH ACT ANALYSIS
Sanaa Ilyas,Qamar Khushi
Academic Research International , 2012,
Abstract: The present study aimed at exploring the communicative functions of status updates on Facebook. Moreover, how identities were established and represented through language were also examined. For this purpose the status updates were analyzed through Searle’s Speech Act framework. The sample comprised 60 males and females in the age group of 18-24 years. A total of 171 status updates were collected for 5 consecutive days and then the data were categorized according to the devised coding. The results revealed that status messageswere most frequently constructed with expressive speech acts, followed by assertives and directives. In addition, a new category of poetic verses was also found in the data. The findings also showed that various socialization patterns emerge through the sharing offeelings, information and ideas.
Impact of Computer Aided Instruction on the Students Achievement in Educational Research and Statistics
Md. Aktaruzzaman,Khushi Muhammad
International Journal of Computer Science Research and Application , 2011,
Abstract: Teaching learning process may be so complex that it can be considered as a ‘black box’ whose mechanisms are not fully understood. However, research into the nature of the learning process has thrown some light on what happens inside the ‘black box’. This has enabled educational technologists to structure the input (teaching methods, curriculum, educational aids, etc.), to systems of this type in such a way that optimal assimilation of the knowledge and skills takes place during the learning process, hence maximize the quality of the output. Teaching method is one of the most important inputs to the teaching learning process which can be structured in various ways and with different dimensions. This study examined the effect of computer aided instruction on student achievement in educational research and statistics course as compared to traditional method of instruction. An experiment was conducted with the students of three different programs of session 2009-2010 studying at Islamic University of Technology (IUT). The study was conducted using post-test only equivalent group design with matched groups based on grade point average of the winter semester of the academic year 2009-2010. Perfectly matched fourteen pairs of students were selected and assigned randomly to the experimental and the control groups. Students of the experimental group received computer aided instruction, for a period of eight weeks in the form of presentation and tutorials and the control group was taught through the traditional method of instruction. Two null hypotheses were tested by analysing the data on achievement test. The results revealed that the experimental group outperformed the control group and there was no significant difference in the overall mean achievement scores of the three subgroups of the experimental group. The main objective of this study was to develop a well-structured computer aided instructional package for educational research and statistics course so that the learners both students and teachers can understand the theory and at the same time implement the theory into practice.
A COMPARISON OF TRADITIONAL METHOD AND COMPUTER AIDED INSTRUCTION ON STUDENTS ACHIEVEMENT IN EDUCATIONAL RESEARCH
Md. Aktaruzzaman,Dr. Khushi Muhammad
Academic Research International , 2011,
Abstract: Student learning is the focus of teaching learning process. Theorists and practitioners have always been made concerted efforts to facilitate students learning by enhancing the quality of learning experiences. Emergence of learning theories over time reflects the concern of educators to explore process, factors and conditions involved in human learning. Application of predominant learning theories have always been changing and modifying the methods of teaching and learning. This study examined the effect of computer aided instruction on student achievement in educational research course as compared to traditional method of instruction. An experimentwas conducted with the students of three different programs of session 2009-2010 studying at Islamic University of Technology (IUT). The study was conducted using posttest only equivalent group design with matched groups based on grade point average of the winter semester of the academic year 2009-2010. Perfectly matched fourteen pairs of students were selected and assigned randomly to the experimental and the control groups. Students of the experimental group received computer aided instruction, for a period of eight weeks in the form of presentation and tutorials and the control group was taught through the traditional method of instruction. Two null hypotheses were tested by analyzing the data on achievement test. The results revealed that the experimental group outperformed the control group and there was no significant difference in the overall mean achievement scores of the three subgroups of the experimental group. This study was an effort to see how CAI affects the achievement of students in social sciences especially in research and statistics. The main objective of this study was to develop a well structured computer aided instructional package for educational research course so that the learners both students and teachers can understand the theory and at the same time implement the theory into practice.
Studies on improved agrobacterium - mediated transformation in two indica rice (Oryza Sativa L.)
Vinod Saharan, Ram C Yadav, Neelam R Yadav, Khushi Ram
African Journal of Biotechnology , 2004,
Abstract: Agrobacterium tumefaciens strain EHA 105 carrying binary vector pCAMBIA 1301 was used for transformation in two economically important highly recalcitrant indica rice cultivars HKR-46 and HKR-126. High concentrations of acetosyringone in the agrobacterium culture and co-cultivation medium proved to be indispensable for successful transformation. Embryogenic scutellar calli were used for transformation studies. Binary vector pCAMBIA 1301 have been proved efficient for transformation. The percent transient GUS expression found to be higher in cutivar HKR-126 (44.4%) as compared to HKR-46 (28.9%). The percent recovery of hygromycin resistant calli after 4-6 weeks on selection medium was maximum in HKR-126 (52.6%). Key Words: Agrobacterium, indica rice, transformation, acetosyringone. African Journal of Biotechnology Vol.3(11) 2004: 572-575
4-(4-Octyloxybenzoyloxy)benzoic acid
Khushi Muhammad,M. Khawar Rauf,Masahiro Ebihara,Shahid Hameed
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536809003298
Abstract: The title compound, C22H26O5, is an important intermediate for the synthesis of side-chain ligands for polymeric liquid crystals. The octyl group is coplanar with the central C6O moiety, where the maximum deviation of a C atom in the octyl group from the C6O plane is 0.161 (5) . The crystal structure is stabilized by intermolecular O—H...O hydrogen bonds.
Physical Factors Affecting in Vitro Replication of Foot and Mouth Disease Virus (Serotype “O”)
Muhammad Taslim Ghori*, Khushi Muhammad and Masood Rabbani1
Pakistan Veterinary Journal , 2011,
Abstract: Effect of physical factors (temperature, pH and UV light) on replicating ability of “O” type of Foot and Mouth Disease (FMD) virus on Baby Hamster Kidney (BHK) cell line was determined. The freshly grown FMD virus containing 106 units of tissue culture infective dose (TCID50) was divided into aliquots. Each of the 9 virus aliquots was exposed to 37, 57 or 77 C for 15, 30 or 45 minutes, respectively. Each of the 5 virus aliquots was mixed with MEM-199 maintenance medium having pH 3, 5, 7, 9, or 11. Similarly, each of the 3 aliquots having 1 mm depth of the medium was exposed to ultraviolet light (252.7 nm wavelength: one foot distance) for 15, 30 or 45 minutes. Each of the virus aliquot exposed to either of the temperature, pH or ultraviolet light (UV) for either of the interaction time was inoculated to 8 wells of the 96-well cell culture plate containing complete monolayer of BHK cell line. One row of 8 wells served as virus control and other row of 8 wells served as control for monolayer of the BHK-21 cell line. The plates were incubated at 37°C for 48 hours. It was observed that temperature of 57 and 77 C inactivated the virus within 15 minutes. The virus when admixed in the MEM-199 maintenance medium having pH 3, 5, 9 or 11, of the medium inactivated the virus while pH 7 did not show any detrimental effect on its survival. The ultraviolet light for 15, 30 or 45 minutes showed undetectable effect on survival of the virus as either of the virus aliquot exposed to the UV light for either of the interaction time showed cytopathogenic effects (CPE). It was concluded that the temperature of 57°C or higher for 15 minutes, acidic pH (below 5) or basic pH (more than 9) may inactivate the FMD virus.
4-(4-Propoxybenzoyloxy)benzoic acid
Khushi Muhammad,M. Khawar Rauf,Masahiro Ebihara,Shahid Hameed
Acta Crystallographica Section E , 2008, DOI: 10.1107/s1600536808016942
Abstract: The title compound, C17H16O5, is an important intermediate for the synthesis of side-chain ligands for polymeric liquid crystals. The propoxy and benzoic acid groups subtend dihedral angles of 4.36 (6) and 55.35 (6)°, respectively, with the central benzoyloxy unit. The crystal structure is stabilized by an intermolecular O—H...O hydrogen bond.
Antigenic characterization of avian influenza H9 subtype isolated from desi and zoo birds
Farrukh Saleem,Muhammad Mahmood Mukhtar,Khushi Muhammad,Muhammad Javed Arshed
Microbiology Research , 2011, DOI: 10.4081/mr.2011.e13
Abstract: Avian influenza is a viral infection which affects mainly the respiratory system of birds. The H9N2 considered as low pathogenic avian influenza (LPAI) virus and continuously circulating in poultry flocks causing enormous economic losses to poultry industry of Pakistan. As these viruses have RNA genome and their RNA polymerase enzyme lacks proof reading activity which resulted in spontaneous mutation in surface glycoproteins (HA and NA) and reassortment of their genomic segments results in escape from host immune response produced by the vaccine. Efforts made for the isolation and identification of avian influenza virus from live desi and zoo birds of Lahore and performed antigenic characterization. The local vaccines although gives a little bit less titer when we raise the antisera against these vaccines but their antisera have more interaction with the local H9 subtype antigen so it gives better protective immune response. Infected chicken antisera are more reactive as compare to rabbit antisera. This shows that our isolates have highest similarity with the currently circulating viruses. These results guided us to devise a new control strategy against avian influenza viral infections. The antigenic characterization of these avian influenza isolates helped us to see the antigenic differences between the isolates of this study and H9 subtype avian influenza viruses used in vaccines. Therefore, this study clearly suggests that a new local H9 subtype avian influenza virus should be used as vaccinal candidate every year for the effective control of influenza viral infections of poultry.
A qualitative study of the aspirations and challenges of low-income mothers in feeding their preschool-aged children
Herman Allison N,Malhotra Khushi,Wright Gretchen,Fisher Jennifer O
International Journal of Behavioral Nutrition and Physical Activity , 2012, DOI: 10.1186/1479-5868-9-132
Abstract: Background The prevalence of obesity among preschool-aged children has increased, especially among those in low-income households. Two promising behavioral targets for preventing obesity include limiting children’s portion sizes and their intake of foods high in solid fats and/or added sugars, but these approaches have not been studied in low-income preschoolers in the home setting. The purpose of this study was to understand the contextual factors that might influence how low-income mothers felt about addressing these behavioral targets and mothers’ aspirations in feeding their children. Methods We recruited 32 English-speaking women in Philadelphia, Pennsylvania who were eligible for the Supplemental Nutrition Assistance Program and who were the biologic mothers of children 36 to 66 months of age. Each mother participated in 1 of 7 focus groups and completed a brief socio-demographic questionnaire. Focus group questions centered on eating occasions, foods and drinks consumed in the home, and portion sizes. Each focus group lasted 90 minutes and was digitally recorded and transcribed verbatim. Three authors independently identified key themes and supporting quotations. Themes were condensed and modified through discussion among all authors. Results Thirty-one mothers identified themselves as black, 15 had a high school education or less, and 22 lived with another adult. Six themes emerged, with three about aspirations mothers held in feeding their children and three about challenges to achieving these aspirations. Mothers’ aspirations were to: 1) prevent hyperactivity and tooth decay by limiting children’s sugar intake, 2) use feeding to teach their children life lessons about limit setting and structure, and 3) be responsive to children during mealtimes to guide decisions about portions. Especially around setting limits with sweets and snacks, mothers faced the challenges of: 1) being nagged by children’s food requests, 2) being undermined by other adults in the family, and 3) having bad memories from childhood that made it hard to deny children’s food requests. Conclusions Although the primary aspirations of low-income mothers in feeding their preschool-aged children were not focused on children’s weight, these aspirations were compatible with obesity prevention strategies to limit children’s portion sizes and their intake of solid fats and/or added sugars.
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