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Search Results: 1 - 10 of 461657 matches for " Khorsand A. "
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Amyloidosis Involving Only Periodontium:Report of a Case
A. Khorsand,G. Saaveh
Journal of Dentistry of Tehran University of Medical Sciences , 2007,
Abstract: Amyloidosis includes a wide range of disorders characterized by deposition of amyloid in different organs and tissues. Localized gingival enlargement due to accumulation of amyloid without involvement of other organs is a very rare condition. This article describes a 31-year-old male patient with amyloidosis involving only the periodontium of the anterior mandibular teeth with localized severe horizontal alveolar bone loss. To our knowledgethis is the first case report that documents this condition.
Association between Asthma and Periodontal Disease
S. Yaghobee,M. Paknejad,A. Khorsand
Journal of Dentistry of Tehran University of Medical Sciences , 2008,
Abstract: Objective: An association between poor oral health and chronic lung disease has recently been reported. The purpose of this study was to explore this potential association between asthma and periodontal disease.Materials and Methods: This is a descriptive case controlled study. The samples were selected from patients referred to respiratory disease clinic in a hospital in Tehran, Iran. The study population comprised of one hundred individuals: fifty asthmatics and fifty asthmatic controls evaluated for Plaque index (PI), Gingival index (GI), Papillary Bleed-ing index (PBI), Periodontal Disease index (PDI) and Calculus index (CI). The data were analyzed by SPSS software.Results: There were significant differences between asthmatics and non-asthmatic sam-ples in PI, GI, BOP, and PDI (P<0.01). However, there was no such differences in CI be-tween the two groups (P=0.084).Conclusion: The results of the present study support recent published reports advocating a relationship between respiratory disease and periodontal health status.
A comparative study on Benzydamine HCL 0.5% and Acetaminophen Codeine in pain reduction following periodontal surgery
Khoshkhoonejad AA.,Khorsand A.,Rastgar F. Dentist
Journal of Dental Medicine , 2004,
Abstract: Statement of Problem: Systemic analgesics are frequently prescribed for pain reduction following periodontal surgery. This type of treatment, however, brings about some disadvantages due to its late effect and inherent side effects. Benzydamine hydrochloride mouth wash is a non steroidal anti-inflammatory drug with local anaesthetic properties. Side effects of benzydamine are minor such as tissue numbness, burning and stinging. It brings relief to pain and inflammation rapidly. Purpose: The goal of this study was to compare benzydamine HCL 0.15% and Acetaminophen codeine as analgesics following periodontal surgery. Materials and Methods: This clinical study was performed on 18 patients referred to periodontics Department, Faculty of Dentistry, Tehran University of Medical Sciences. All patients were affected with chronic mild or moderate periodontitis and required surgery at least at two oral sites with similar lesions. Each patient received benzdamine HCL after first surgery and Acetaminophen codein following second operation. Pain reduction was evaluated by Visual Analog Scale (VAS). Data were analyzed with Wilcoxon-Signed and Mann-Whitney non-parametric tests. Results: Analgesic effect of Acetaminophene codeine was significantly more than that of benzydamine HCL following Reriodontal surgery (P=0.008). No significant difference was found between analgesic effects of Acetaminophene codeine and benzydamine HCL in patients with chronic mild periodontitis (P=0.9), and in cases that osteoplasty (P=0-31) or no osseous surgery (P=0.18) were performed. Conclusion: In cases with mild post-operative pain following periodontal surgery, Benzydamine HCL and be prescribed as an analgesic. However, in other cases this mouth wash should be prescribed along with Acetaminophene codein to reduce systemic drugs consumption.
Evaluation of periodontal condition of menopause women with osteoporosis and osteopenia and comparison with control group
Khorsand A.,Paknejad M.,Vakili F.
Journal of Dental Medicine , 2006,
Abstract: Background and Aim: Several risk factors directly affect the development of periodontal diseases. Also some systemic diseases act indirectly as predisposing and aggrevating factors. Osteoporosis is one of these factors and one of its main causes is lack of physical activity in postmenopause period. The incidence of osteoporosis is increasing in our country. The goal of this study was to evaluate the periodontal condition of women with osteoporosis and osteopenia referred to bone densitometric division of Loghman hospital in 2003 and compare to control group. Materials and Methods: In this case control study based on BMD (Bone Mineral Density) measurement of back and thigh using DEXA method, 60 patients referred to bone densitometric division of Loghman hospital, were randomly selected. Cases were divided into three groups, 20 with osteoporosis, 20 with osteopenia and 20 normal cases. Periodontal indices consisting of plaque index (PI), tooth loss (TL), gingival recession (GR), probing pocket depth (PPD) and papilla bleeding index (PBI) were evaluated by clinical and radiographic examination. Data were analyzed by Kruskall Wallis and Dunn tests with p<0.05 as the limit of significance. Results: PBI, PI and TL were significantly higher in osteoporotic group than osteopenic and normal group. PPD was not different in the three groups. Due to the low prevalence of recession in our study, this parameter was not included in the statistical analysis. Conclusion: It seems that osteoporosis does not increase the incidence of periodontal diseases because it affects bone quality rather than quantity. In osteoporosis calcium deficiency and increasing age lead to decreased physical activity and ultimately affect the patient's oral hygiene performance. Thus, periodontal manifestations are presented as gingival bleeding and gingivitis.
Comparative study of the possibility of interdental papilla reconstruction using connective tissue graft with and without Emdogain
Soleymani Shayesteh Y.,Khorsand A.,Habibi B.
Journal of Dental Medicine , 2008,
Abstract: Background and Aim: Improving esthetics is a major goal in periodontal treatments and specially reconstruction of dental papilla is of great importance. Different techniques have been developed, however the results are not completely predictable. The aim of the present study was to compare the possibility of papilla reconstruction using connective tissue graft with and without Emdogain.Materials and Methods: In this clinical trial, 40 class II lost interdental papilla (Nordland- Tarnow classification) in 18 patients (4 male and 14 female) were studied. Samples were randomly devided into two groups. Case group was treated by connective tissue graft and emdogain (Straumann-USA) and controls were treated using connective tissue graft only. Periodontal parameters including papilla height (PH), periodontal pocket depth (PPD) and clinical attachment level (CAL) were measured before surgery, and 3 and 6 months after treatment. At the tenth days and 1 month after treatment only the papilla height was measured. Repeated measures analysis was used for data analysis with p<0.05 as the level of significance.Results: In the control group the mean papilla height changed from 3.38 0.89 to 2.85 0.93 on the 3rd month and 2.90 0.95 on the 6th month. The mean PPD changed from 2.8 0.68 to 2.55 0.70 on the 3rd month and 3.06 1.25 on the 6th month. The mean CAL changed from 3.88 1.29 to 3.79 1.25 on the 3rd month and 4.11 1.44 on the 6th month. In test group the mean papilla height changed from 2.98 0.91 to 2.45 1.55 on the 3rd month and 2.55 1.48 on the 6th month. The mean PPD changed from 2.75 1.49 to 2.63 1.38 on the 3rd month and 2.88 1.39 on the 6th month. The mean CAL changed from 3.75 1.24 to 4.01 1.45 on the 3rd month and 4.28 1.63 on the 6th month. These differences were not significant between the studied groups (P>0.05).Conclusion: Based on the results of this study, use of connective tissue with or without emdogain is not effective in interdental papilla reconstruction.
Synthesis and characterization of a narrow size distribution of zinc oxide nanoparticles
Khorsand Zak A, Razali R, Abd Majid W, Darroudi M
International Journal of Nanomedicine , 2011, DOI: http://dx.doi.org/10.2147/IJN.S19693
Abstract: thesis and characterization of a narrow size distribution of zinc oxide nanoparticles Methodology (5969) Total Article Views Authors: Khorsand Zak A, Razali R, Abd Majid W, Darroudi M Published Date July 2011 Volume 2011:6 Pages 1399 - 1403 DOI: http://dx.doi.org/10.2147/IJN.S19693 A Khorsand Zak1,2, R Razali1, WH Abd Majid1, Majid Darroudi2 1Low Dimensional Material Research Center, Department of Physics, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia; 2Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran Abstract: Zinc oxide nanoparticles (ZnO-NPs) were synthesized via a solvothermal method in triethanolamine (TEA) media. TEA was utilized as a polymer agent to terminate the growth of ZnO-NPs. The ZnO-NPs were characterized by a number of techniques, including X-ray diffraction analysis, transition electron microscopy, and field emission electron microscopy. The ZnO-NPs prepared by the solvothermal process at 150°C for 18 hours exhibited a hexagonal (wurtzite) structure, with a crystalline size of 33 ± 2 nm, and particle size of 48 ± 7 nm. The results confirm that TEA is a suitable polymer agent to prepare homogenous ZnO-NPs.
The Effect of Piascledine in the Treatment of Chronic Periodontitis
M. Paknejad,A. Khorsand,S. Yaghobee,M. Nasiri
Journal of Dentistry of Tehran University of Medical Sciences , 2007,
Abstract: Objective: The aim of this study was to evaluate the clinical efficacy of an herbal medi-cine, Piascledine, on the treatment of chronic periodontitis.Materials and Methods: Twenty-four patients with chronic periodontitis participated in this interventional case control investigation. After initial screening the subjects were di-vided into case and control groups. Clinical measurements including plaque index (PI), bleeding on probing (BOP), probing pocket depth (PPD), bone level (BL) and clinical at-tachment level (CAL) were recorded for both groups, before and one month after scaling and root planing (SRP). The case group received 300 mg Piascledine capsules once a day for three months and the control group was only treated with SRP. The measurements were repeated in both groups at the 3 and 6 month recall visits.Results: Improvements were observed in all clinical parameters in both groups during the study period. PI as a covariate factor showed no significant difference between the two groups (P>0.05). On the other hand CAL, BOP, PPD and BL showed reduction in all pa-tients, but no significant difference was found between the two groups.Conclusion: According to the results obtained in the present study, Piascledine does not seem to have a favorable effect in the treatment of chronic periodontitis.
Evaluation of Platelet-Rich Plasma in Combination with Deproteinized Bovine Bone Mineral in the Rabbit Cranium; A Pilot Study
Y. Soleymani Shayesteh,A. Khorsand,P. Motahhary,M. Dehghan
Journal of Dentistry of Tehran University of Medical Sciences , 2005,
Abstract: Statement of Problem: Reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. Platelet-rich plasma (PRP) offers a new and potentially useful adjunct to bone substitute materials (e.g. Xenografts) inoral and maxillofacial bone and implant reconstructive surgery.Purpose: An animal study was carried out to investigate the influence of PRP on the regeneration of non-critical sized bony defects, treated with Deproteinized Bovine Bone Mineral (DBBM).Materials and Methods: Eight New Zealand white rabbits were included in this randomized, pilot study. Three equal cranial bone defects (3×6 mm) were created and immediately grafted with DBBM and PRP+DBBM; one of them was left unfilled to serve as a control. The defects were evaluated using histologic and histomorphometricanalysis at 2, 4, 8 and 12 weeks.Results: The histomorphometric findings showed a significant increase in bone area and trabecular maturity in experimental defects as compared to the control at 4, 8 and 12 week intervals. A significant increase in bone formation was seen with the additionof PRP to DBBM at 2, 4 and 8 week intervals. At 12 weeks, the level of bone formation was similar between the two groups. There was also a significant increase in the rate of biodegradation of the DBBM particles with the addition of PRP at 2, 4, 8 and 12 weeks.No foreign body reaction and severe inflammation was seen in any of specimens.Conclusion: Within the limitations of this pilot study, it was concluded that the addition of PRP to Xenogenic bone substitute material in non-critical-sized defects of the rabbit cranium showed a histomorphometric increase in bone formation (until the 8th week ofhealing) and a greater amount of biomaterial degradation throughout the study period.
Comparison of Systemic Ciprofloxacin in Elimination of A.a from Active Sites with Combination of Metronidzole and Amoxicillin in Patients with Aggressive Periodontitis: A Randomized Double Blind Controlled Trial
Y. Soleymani Shayesteh,A. Khorsand,MH. Salary,H. Mehrizy
Journal of Dentistry of Tehran University of Medical Sciences , 2004,
Abstract: Statement of Problem: The elimination of Actinobacillus actinomycetemcomitans (A.a) is a key factor for achieving a successful treatment in patients with aggressive periodontitis(AgP) whom harboring this organism. This micro organism’s capability to invade to host’s tissues, makes its eradication with mechanical therapy (eg. flap surgery, scaling, oral hygiene) very difficult, so there is no other way than using a systemic antibiotic. But whichantibiotic is the best one? The Ciprofloxacin is the only antibiotic which can suppress all strains of A.a.Purpose: The aim of this study was to compare the effectiveness of Ciprofloxacin in elimination of A.a in active sites of AgP patients with combination of Metronidazole and Amoxicillin.Materials and Methods: This study was a randomized double blind controlled clinical trial. Twenty four patients with clinical diagnosis of AgP and detection of A.a in their pockets were randomly divided into two groups. The 12 patients in test group receivedCiprofloxacin (10 days BID 1gr) plus the placebo capsules representing Metronidazole and Amoxicillin. The other 12 patients named control group, received Metronidazole (7 days TID 750mg) plus Amoxicillin (7 days TID 1.5gr) and the placebo tablet representingCiprofloxacin. Neither the patients nor the doctors knows the grouping sequences. Bacteria Culturing and measurement of Gingival Index (GI) and plaque Index (PI) were done at the baseline and repeated about 10 days after prescribing the medicines. T- test and chi-square test were used for Statistical analysis.Results: There was no difference between two groups in the A.a Positives sites, GI scores and PI scores at the baseline. Ciprofloxacin eliminates A.a from 91.7% of sites and Metronidazole plus Amoxicillin eliminate A.a from 81.3% of sites. There was nosignificant difference between the test and control groups. The mean PI score for test and control groups were 1.39±0.66 and 1.39±0.88 respectively at the baseline and these values were 1.27±0.6 and 1.43±0.81 after receiving the designed medicine. There were nodifferences inter and intra groups at any time (P>0.05).Conclusion: Ciprofloxacin is as effective as Metronidazole plus Amoxicillin in elimination of A.a from active sites in AgP patients. Their longitudinal effects on clinical parameters such as probing depth, clinical attachment level, bleeding on probing and microbial flora need to be investigated.
A clinical and radiographical evaluation on the treatment of grade II furcation involvement of mandibular molars by demineralized bone matrix (Dynagraft) as compared with coronally positioned flap (CPF)
Khorsand A.,Soleimani Shayesteh Y.,Talaci Pour AR.,Negaresh AH.
Journal of Dental Medicine , 2004,
Abstract: Statement of Problem: One of the problems associated with the treatment of periodontal diseases is caused through the extension of disease toward furcation area. Several techniques in Conservative, Resective and Regenerative categories have been suggested for the treatment of furcation involvement."nPurpose: The aim of this study was to compare the results of the treatment of grade II furcation involvement in mandibular molars using an allograft material named 'Dynagraft' (a type of demineralized bone matrix) and the coronally positioned flap. Materials and Methods: In this randomized controlled clinical trial study, twelve patients (9 females and 3 males), aged 25 to 40, suffering from bilaterally grade II furcation involvement of mandibular molars who referred to dental faculty Tehran University of medical Sciences, were investigated. The molars of one side were treated by Dynagraft whereas those of the opposite side underwent the CPF method. Measurements of the probing pocket depth (PPD), clinical attachment level (CAL), keratinized gingiva (KG) and horizontal probing depth (HPD) were recorded at baseline, 3 and 6 months after surgery. In order to investigate the bone radiographic changes, radiovisiography at the mentioned periods in addition to clinical investigation, were performed. For statistical analysis, Paired West was used."nResults: The mean PPD reduction three months and six months after the operation were 1.75 mm and 2.25mm, respectively in the Dynagraft (test) group whereas 1.26mm and 1.27mm in the CPF (control) group (P<0.005). The mean attachment gain three months and six months after the operation were 1.1 mm and 1.5mm respectively in the test group, and 0.2mm and 0.3mm in the control group (P<0.005). The mean KG reduction three months and six months after the operation were 0.5mm and 0.6mm respectively in the test group and those of the control group were 1.1mm and 1.1mm. The mean HPD reduction three months and six months after the operation were 1.55mm and 2mm respectively in the test group (P<0.005) and 0.55mm and 0.55mm in the control group (PO.01). Radiovisiography of the mentioned areas three months and six months after the operation confirmed the changes obtained from clinical measurements, showing appreciable reconstructive results (Bone filling) in the test group as compared with the control group. Moreover, root resorption was not observed."nConclusion: Based on the results of this study, Dynagraft can be used as an appropriate material in the treatment of grade II furcation involvement in mandibular molars. However, for a th
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