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Search Results: 1 - 10 of 1087 matches for " Khatami GH "
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"Incidence And Epidemiology Of Esophagitis In Children Admitted To Endoscopy Unit Medical Center Of Children In Tehran "
Rafeey M,Khatami GH
Tehran University Medical Journal , 2004,
Abstract: Background: There has been a little attention to pediatrics esophagus problems until recent years. The term esoghagitis can be used to described chemical, infectious, inflammatory, ischemic, immunologic and degenerative abnormalities. Prevalence of reflux esophagitis varies between 2 to 5 percent of general population but little data about its incidence in pediatric age groups. The aim of this study was to evaluate the epidemiology and prevalence of esophagitis and study of symptom, diagnostic measures, therapeutic intervention and prevention of its complication. Materials and Methods: In this prospective and cross sectional study 500 patient under16 years with upper digestive complaints or alteration of their state of health under went upper endoscopy, with special attention paid to esophagus. Results: Among 500 children (205 male, 207 female), pathology reported esophagi is in 325 cases. Majority of the patient were 8 to12 years. Most common complaints was abdominal pain (45/7%) and the second complaints was vomiting (13%), but most common complaints in severe esophagitis was melena (66%) and hematemes(18/8%). Most of patient (63% ) had a mild grade of esophagitis. When difference between endoscopy and pathology compared: Mild esophagitis in endoscopy (67%) ,but in pathology was (63%), moderate esophagitis (14/7%) in endoscopy was (17%) in pathology and severe form 2/8% in endoscopy but (4/9%)in pathology. Conclusion: According to results of our study in children age group with chronic abdominal pain ,vomiting ,excessive regurgitation, failure to thrive, we noticed that esophagitis is common etiologic factor. Histological esophagitis frequently occur in the absence of gross endoscopic findings and we need biopsy and histological examination to confirm diagnosis.
GH.R Khatami
Iranian Journal of Pediatrics , 1985,
Abstract: Amebiasis, caused by Entamoeba histolytica, may be an acute or chronic disease. The organism is a protozoan and exists as trophozoite and in cystic form. The trophozoite remains harmless after colonization in the large intestine. The infection involves most frequently cecum and ascending colon and less frequently the rectosigmoid. Asymptomatic intraluminal Amebiasis is the most frequent form of infection. The diagnosis of Amebiasis is missed in more than 40% of the infected children as the physicians seldom think of it. If stool cultures and rectoscopy are negative for Amebiasis, serologic tests should be performed. Amebic colitis has to be differentiated from ulcerative colitis, corhn's disease and bacillary dysentery. Prophylactic measures consist of boiling of the drink water and eradication of the enteral Amebiasis. Nitroimidazole (Metronidazole) and its more recent derivative imidazole are effective in all three kinds of infection, i.e. itraluminal, intramural and systemic (Hepatic) Amebiasis.
Survey of Congenital Major Malformation in 10,000 Newborns
F Khatami,Gh A Mamuri
Iranian Journal of Pediatrics , 2005,
Abstract: Background: Congenital major malformations (CMM) are one of the most important causes of admission of newborns in hospitals, and neonatal morbidity and mortality. The incidence of CMM depends age of affected patients. In newborns infants, it is approximately 2-3%. The great majority of CMM occurs sporadic (86%), genetic and exogenic factors both play a role in their occurrence. The aim of this research is to determine the incidence and the associated factors with CMM in Iran. Methods: This is a prospective, analytical, and descriptive study. This study was performed with simple randomized sampling for two year, which involved all live born infants without no anomaly (control group) and all newborns with CMM (patients group). There was a total of 10450 infants. Stillbirth infants and those who died in few hours after birth were excluded and finally 9200 newborns were enrolled in our study. Findings: As a result, the incidence of CMM was approximately 1.8%, isolate malformation (74%) were more common than multiple malformations, musculoskeletal system were the most affected system, and multifactorial inheritance accounted the most etiologic factor. There was no predominance of the two sexes in patients group. Maternal age of over 30 years, consanguineous marriage and positive familial history of CMM, were associated with higher incidence of CMM. Rout of delivery and incidence of prematurity had no CMM incidence rate. Conclusions: Although we got the same result as other investigations, if we enrolled abortions, stillbirth infants and if we used screening tests and genetical studies, the incidence of CMM would be more than 1.8%. Smoking, using drugs, high fever, viral rash and ultrasonography during pregnancy may be probable etiologic factors in CMM. We recommend multicenteral and larger studies for CMM in Iran.
Tumors of the liver; a ten year study in Children Medical Center
Farahmand F,Khatami GH,Mehrabi V.A,Mahjoob F
Tehran University Medical Journal , 2007,
Abstract: Background: The aim of this study was to review the frequency, histopathology and outcome in children with tumors of the liver. Methods: Included in this retrospective/descriptive study were 30 children treated for liver tumors from 1375-1384 (ca. 1996-2005), at Children’s Hospital Medical Center, Tehran, Iran. We included the clinical, radiologic, and pathologic data of our patients, focusing on the frequency, etiology and outcome. Results: Patient ages ranged from three months to 12 years (median 3.8 years), with 18 males (60%) and 12 females (40%). Of these, 17 patients had hepatoblastoma (55.66%), including 13 males and four females, with an age range of six months to five years. Four cases (13.33%) had neuroblastoma. Hepatocellular carcinoma (HCC) was found in three cases (10%), all of whom were carriers of hepatitis B. Two cases (6.66%) were diagnosed with mesenchymal hamartoma, two cases (6.66%) with hemangioendothelioma and two cases (6.66%) with rhabdomyosarcoma and leiomyosarcoma of the biliary tract. Abdominal swelling and hepatomegaly were seen in all of patients. Jaundice was observed in two cases. Serum alpha-fetoprotein levels greater than 500 ng/ml were seen in 17 cases (56.66%). All patients were receiving specific treatment. The three-year survival rate was 65% for hepatoblastoma and 2% for HCC Conclusion: With the introduction of specific treatment, the survival rate for children with tumors of the liver has significantly increased. Further improvement can be achieved using diagnostic biopsy for hepatoblastoma, although it may result in complications, and preoperative chemotherapy followed by complete surgical excision (per International Society of Pediatric Oncology guidelines), yielding an outstanding survival rate of 80%.
Radiographic Findings of Pulmonary Tuberculosis in Tehran in Comparison with Other Institutional Studies
A. Jamzad,M. Shahnazi,A. Khatami,Gh. Azimi
Iranian Journal of Radiology , 2009,
Abstract: Background/Objective: Tuberculosis (TB) is one of the most common worldwide infections, especially in developing countries. Early diagnosis is very important for prevention of the chronic form of the disease and sequel formation. Chest x-ray (CXR) is an easy, feasible, non-expensive and quick tool for the diagnosis of pulmonary tuberculosis. "nPatients and Methods: We retrospectively evaluated 200 chest x-rays of secondary pulmonary TB cases in university-affiliated hospitals. These cases were all proved by a positive sputum smear or culture for mycobacterium tuberculosis. "nResults: In this study, we correlated CXR findings of 100 male and 100 female patients. The peak age of involvement in both groups was 61-80 years. None of the chest x-rays were normal. The main radiographic findings were consolidation-infiltration, fibrosis, pleural effusion, cavitation, pleural thickening and bronchiectasis. Mediastinal lymphadenopathy was detected in 9% of the cases. Pulmonary infiltration with consolidation was the most common finding (55%). Miliary shadowing, atelectasis and pneumomediastinum were the least common presentations. Lymphadenopathy was more common in 40 to 60-year-old women. Right lung involvement was more common than the left side and the upper zones were involved in most cases. The most common underlying diseases were hypertension and diabetes mellitus. Infiltration in diabetic patients and fibrotic appearances in hypertensive patients were common findings. "nConclusion: There was no significant difference between our data and the other studies carried out in Iran. The patients were younger in the studies from other countries. However, cavitary lesions were more common in other studies than this study, which seems to be due to the higher prevalence of underlying diseases such as HIV or diabetes.
Effectiveness of Combination Therapy with Honey in H.Pylori Eradication in Pediatrics Medical Centre
A. Khodadad,Gh.R. Khatami,Z.N. Hatmi,H. Karami
Tehran University Medical Journal , 2006,
Abstract: Background: There are several million new cases of peptic disease annually. The disease has a various range of presentations. Gram negative helicobacter pylori bacilli is considered as an etiologic factor in this disease. Goal of treatment in peptic disease is eradication of the helicobacter pylori (HP). Combination therapy has been implemented in the treatment of this disease. Different modalities have been recommended up to now. In order to lower adverse effects, cost and drug resistance, researchers have introduced a new combination therapy in which honey is substituted for metronidazole. Methods: A step II of clinical trial was designed. The sample size was 15 children. Diagnosis of HP infection was confirmed with histopathology. Treatment regimen consisted of omeprazole, amoxicillin, bismuth and honey. After a 3-4 week follow- up, eradication was evaluated. Results: 15 children completed the follow- up period. Mean age of patients was 9.4 years. Treatment effectiveness was 80 percent. Conclusion: Combination therapy with 3 drugs along with honey has significant effectiveness on HP eradication.
Iranian Journal of Child Neurology , 2012,
Evaluation of diagnostic test accuracy studies
Alireza Khatami
Dermatology and Cosmetic , 2011,
Abstract: "nIn the recent years, advances in different fields of technology have been resulted in a dramatic increase in the diagnostic methods and tests in different branches of clinical medicine with a consequent increase in the number of scientific publications related to the application of those tests and methods in the diagnosis or prevention of diseases. Dermatology is not an exception. Since, evidence-based medicine emphasizes on the appropriate use of the current best clinical research evidence in the diagnosis or treatment of each individual patient acknowledging his/her values, the capability of dermatologists in appraisal and application of the publications, which reports the results of diagnostic test accuracy studies cannot be ignored. In this article, after a brief review on basic issues in diagnostic test accuracy studies, principles of critical appraisal of these studies, from an evidence-based viewpoint, will be discussed. General strategies for evaluation of validity, applicability and quality assessment of a diagnostic test study will be provided.
A Note On Gorenstein Injective Dimension
Leila Khatami
Mathematics , 2006,
Abstract: The Chouinard's formula for injective dimension is extended to the Gorenstein injective dimension.
The smallest part of the generic partition of the nilpotent commutator of a nilpotent matrix
Leila Khatami
Mathematics , 2013,
Abstract: Let $k$ be an infinite field. Fix a Jordan nilpotent $n$ by $n$ matrix $B = J_P$ with entries in $k$ and associated Jordan type $P$. Let $Q(P)$ be the Jordan type of a generic nilpotent matrix commuting with $B$. In this paper, we use the combinatorics of a poset associated to the partition $P$, to give an explicit formula for the smallest part of $Q(P)$, which is independent of the characteristic of $k$. This, in particular, leads to a complete description of $Q(P)$ when it has at most three parts.
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