OALib Journal期刊

ISSN: 2333-9721




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匹配条件: “Khaniki M” ,找到相关结果约400146条。
Histopathological Study of Hysterectomy Operations in A University Clinic in Tehran From 2005 to 2009
Mahmoud Khaniki,Mahsa Shojaie,Azam M Tarafdari
Journal of Family and Reproductive Health , 2011,
Abstract: Objective: We intended to determine causes and histological pattern of hysterectomies in an Iranian population.Materials and methods: Archived reports of pathology department of a university hospital dated March 2005 to March 2009 were retrospectively reviewed. Age, chief complaint, type of operation including abdominal, vaginal and subtotal hysterectomy, the indication of the operation and the pathology of the specimen were retrieved from the records.Results: The average rate of hysterectomy was 219 per year. The average age of the patients was49.6±11.3. About 40% of cases aged 45-54 years. The main chief compliant was abnormal uterinebleeding (62.2%). The leading preoperative indication for hysterectomy operations were uterine leiomyoma (24.8%) and then abnormal uterine bleeding and abdominal/pelvic mass. The most frequentpathologic findings were leiomyoma (22.0%) and adenomyosis (12.1%). In 11.8% of hysterectomy specimens no pathologic lesion was found.Conclusion: The hysterectomy is rather common in Iran with age dependent pattern of indications and corresponding pathologies.
Heavy Metals in Edible Green Vegetables Grown Along the Sites of the Zanjanrood River in Zanjan, Iran
A. Eslami,Gh. R. Jahed Khaniki,M. Nurani,M. Mehrasbi
Journal of Biological Sciences , 2007,
Abstract: The study investigated the levels of five different heavy metals (Cd, Pb, Zn, Cr and As) in various vegetables including roots and leaves of radish (Raphanus sativus L.), leek (Allium ampeloprasum L.), sweet basil (Ocimum basilicum L.) and parsley (Petroselinum crispum) cultivated along the bank of river passing through the city of Zanjan. The contributions of the vegetable to the daily intake of the heavy metals from the vegetables were determined. Atomic absorption spectrometry was used to estimate and evaluate the levels of these metals in the vegetables. The results of this survey showed the following ranges (mg kgG1): 3.89-32.94, 3.15-27.68, 43.61-223.10, non-detectable and non-detectable for lead, cadmium, zinc, chromium and arsenic, respectively. Some vegetables contaminated high levels beyond the levels given by FAO and WHO for human consumption. When the mean levels of Lead and Cadmium (10.65 and 9.22 mg kgG1) were taken into account the daily intake contribution of the metals was found to be 2.32 and 2 mg for Lead and Cadmium. Increase in vegetable consumption by community the situation could worse in the future.
Protective Effect of Dendrosomal Curcumin Combination on Colon Cancer in Rat
Sarbolouki MN,Alizadeh AM,Khaniki M,Azizian S
Tehran University Medical Journal , 2012,
Abstract: Background: Cancer is a multistep process that develops very rapidly after its onset. Previous studies have confirmed antitumor effects of curcumin (1,7-bis (4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; diferuloylmethane) that can potentially prevent colon cancer development with low side-effects. Different methods have been performed to increase the efficiency and effectiveness of curcumin among which dendrosome, a nanoparticle created by Sarbolouki et al. was used in this study. The present study was undertaken to evaluate the effects of dendrosomal curcumin on rat colon cancer. Methods: In this study which was performed in Cancer Research Center of Tehran University of Medical Sciences in 2010 year, forty rats were equally divided into control, curcumin and curcumin-dendrosome groups. Animals received azoxymethane (15 mg/kg s.c.), a carcinogen, once a week for two weeks. Curcumin (0.2%) and curcumin-dendrosome were administered to the respective animals 2 weeks before the first and 14 weeks after the last azoxymethane injections. Eventually, colorectal specimens from tumoral and adjacent non-tumoral mucosal tissues were fixed in 10% formaldehyde, and passaged and embedded in paraffin. Histopathological and immunohistochemical studies were performed on the specimens. Results: The mean number of lesions, nuclear/cytoplasmic ratio, epithelial stratification, loss of nuclear polarity, goblet depletion, structural abnormality and beta-catenin expression were higher in the control group compared to curcumin and curcumin-dendrosome groups. These parameters had significantly decreased in the dendrosomal curcumin group (P<0.05). Conclusion: The present study shows that dendrosome can be used as a suitable nanoparticle to increase curcumin efficiency in the prevention or treatment of colon cancer.
M. Ghorbanli, Z. Bakand, G. Bakhshi khaniki, S. Bakand
Iranian Journal of Environmental Health Science & Engineering , 2007,
Abstract: The air pollution effects on the activity of antioxidant enzymes were investigated on Nerium oleander and Robinia pseudo acacia in Tehran. Considering the information obtained from the Department of the Environment of Iran, Sorkh Hesar Park as well as South Azadi were selected as two sampling sites representing the unpolluted and polluted area respectively. A number of plant leave samples were collected from both sampling sites simultaneously. The activity of plant enzymes including peroxidase, catalase and ascorbate peroxidase was investigated using spectrophotometric methods. A higher level of peroxidase and catalase enzymes were measured in both plant samples collected from polluted area. However, this higher level was only statistically significant for the activity of peroxidase enzyme in Robinia pseudo acacia plants compare of to the control group (p < 0.05). The lower level of ascorbate peroxidase was observed in Nerium oleander plant leaves collected from the contaminated sampling site (p < 0.05), but though, the activity of this enzyme in Robinia pseudo acacia did not change significantly. The overall plant injury symptoms found in this study demonstrated that both Nerium oleander and Robinia pseudo acacia have a potential to be considered as effective bioindicators to reflect the environmental air quality in polluted areas.
Investigation of Nitrate Concentrations in Some Bottled Water Avaliable in Tehran
GR Jahed Khaniki,M Mahdavi,A Ghasri,S Saeednia
Iranian Journal of Health and Environment , 2008,
Abstract: Background and Objectives: Bottled water is a main beverage at many developed and developing countries. It can be polluted with chemical agents. One of these agents is nitrate which affects the safety of bottled and mineral water and cause healthy effects on consumer health. Today's consumption of bottled water get a grate develop, thus infer of the quality of this matter is compulsive for each consumer."nMaterials and Methods: A descriptive-analytical and cross- sectional study was done with the aim of determination of nitrate in bottled water available in market of Tehran City in 2007. In this study, 18 samples of six various manufacturers of product were examined."nResults: Results showed that the mean of nitrate is 9.02 mg/L and all samples have nitrate bellow 50 mg/L and they are at the standard level. Also, the results of the examinations have good correspondence with the concentration of nitrate on bottled water labels and according to statistic meaningful relation, was considered."nConclusion: The nitrate content of these bottled water available in market of Tehran city is located at the level of national and global standards and it can not be a serious problem for health of consumer.
Release of the Phthalate Esters into Water Stored in Plastic Tumblers
G.H.R. Jahed Khaniki,M. Yunesian,K. Naddafi,J. Nouri
Journal of Applied Sciences , 2006,
Abstract: Phthalates are present in almost all plastic equipments. Phthalates are not chemically but only physically bound to the polymer chains, they may be leached into food and beverages from the packaging material. A study was determined DBP and DEHP release into water stored in plastic tumblers at different temperatures and times. Thirty five disposable plastic tumblers with 200 mL volume, which have manufactured for water and beverages, bought from plastic market. Then, deionized water with different degrees (10 and 80°C) was added into disposable plastic tumblers for a period of 10, 20 and 60 min. Extraction was done and all analyses were carried out on a HPLC system with UV detector. Results showed that the maximum of DBP and DEHP contents into water stored in disposable plastic tumblers are 1.5±0.48 and 0.15±0.08 μg L-1, respectively. Stored hot water with 80°C for 60 min had the highest concentrations of DBP in the other groups of water samples. It was showed that released DBP into water samples has increased at high temperatures and longer period. Also, there was a significant difference in DBP contents in stored water with 10°C for 10 min (p<0.023) and DEHP contents in stored water with 80°C for 20 min (p<0.023), while there wasn`t a significant difference in other DBP and DEHP contents in water samples (p>0.05). It was concluded that released DBP and DEHP levels into water samples has increased at high temperatures and longer times. Therefore, it can have been some concerns about the release of DBP and DEHP from plastic tumblers into hot drinks for consumer.
Detection of Baking Soda in Flat Bread by Direct pH Metery and Alkalinity Measurement
G.H.R. Jahed Khaniki,F. Vaezi,M. Yunesian,R. Nabizadeh
Journal of Applied Sciences , 2007,
Abstract: The objective of this study is evaluation of direct pH metery and alkalinity measurement methods for determination of baking soda in lavash bread (a kind of flat bread) in order to introduce and recommend a good practice of control. For running the experiments, various samples of lavash bread having different concentrations of baking soda were prepared. Ten grams of each sample were mixed with distilled water and then the prepared solutions were filtrated. The filtrates were then analyzed for pH and total alkalinity according to the distractions described in Standard Methods. Results show a significant correlation between the pH values of bread samples and the amount of baking soda. Also, a positive correlation has been observed between the alkalinity of bread samples and used baking soda. By comparing the R2-values specified for these two methods it could be concluded that the direct pH metery method is more reasonable. Furthermore, by this simple method it is possible to accelerate the detection of minute amounts of this chemical in bread.
The Prevalence of Coagulative – Positive Staphylococcus Aureus in Milk by Received in to the Milk Collecting Center of Garmsar City
GH.R Jahed Khaniki,A Kamkar,M.A Tehrani
Journal of School of Public Health and Institute of Public Health Research , 2005,
Abstract: A study was carried out to estimate the prevalence of Coagulase – Positive Staphylococcus aureus in milk collected in the milk collecting center in Garmsar city. Ninety-six raw milk samples (84 composite samples and 12 bulk samples) were collected from Garmsar milk collecting center. Raw milk samples were transferred to laboratory in safe conditions. After serial dilution, the appropriate concentrations (10 -2 to 10 -6) were cultured on Baired- Parker agar medium. The plates were incubated at 37 oC for 2 days (48h). After 48 hours' incubation, the colonies with black centers and light areas were used for staphylococcal assay. The coagulase test was done with rabbit plasma and coagulate- positive colonies were then counted. The results showed that mean counts of coagulate-positive Staphylococcus aureus in composite and bulk milk were 5.4 ×10 5 cfu/ml and 3.2 × 105 cfu/ml, respectively. The counts ranged from 8.6 × 10 4 to 2.1 × 10 6 cfu/ml and 1.4 ×10 5to 5.5 × 10 5 cfu/ ml. The standard deviations were 3.5 × 10 5 cfu/ml and 1.4 × 10 5 cfu/ml respectively. It is clear that the milk collected at this facility was rather heavily contaminated with S. aureus. Therefore, it may constitute a health hazard because of the possible production of enterotoxin in the milk consumed by the people. In order to reduce staphylococcal contamination in milk, it is recommended to treat cases of clinical and subclinical staphylococcal mastitis in livestock. Also, it is necessary to use hygienic procedures during the production process as well as transportation and storage.
Determination of Zinc Contents in Iranian Flat Breads
Gholam Reza Jahed Khaniki
Pakistan Journal of Nutrition , 2005,
Abstract: Zinc is an essential element for the maintenance of good health. It is necessary for the activity of several enzymes involved in energy changes and protein formation. Bread is one of the foods that have some zinc. Bread and other cereal products provide the most of calories and protein intakes of Iranian people in cities. Iranian flat breads such as lavash, taftoon, barbari and sangak generally are produced from soft white wheat flours of higher extraction levels compared to western type breads. The diet of Iranian people is more bread and other cereal products provide as much as 50-90 % of total caloric. For zinc monitoring in flat breads, 36 flat bread samples were collected from bakeries in Tehran city in 2004 and analyzed by flame atomic absorption spectrophotometry for zinc metal. The mean and standard deviation of zinc content in lavash, barbari, taftoon and sangak breads were 12.17 1.91, 10.75 2.64, 10.41 3.54 and 14.25 3.56 mg/kg, respectively. Estimated intake of zinc based on consumption of Iranian flat breads is 3.499 mg per person per day. Flat breads are good sources of zinc and they can supply some of zinc requirements of human body for preventing of zinc deficiency.
Shoot Micropropagation and Microtuberization in Potato (Solanum tuberosum L.) By the Semi-Continuous Bioreactor
Mostafa Ebadi,Alireza Iranbakhsh,Gholamreza Bakhshi Khaniki
Pakistan Journal of Biological Sciences , 2007,
Abstract: The research of Jimene et al. (2002) using semi-continuous fermentors has shown that inducing of tubers during two weeks is observed and their number is not increased after this period. So, it seems that tubers induction during the first two week, in inducing medium finishes. This means that the inducing tissues of tubers and the growth condition of tubers must be provided during this period. In contrast, the total weight of tubers increaser stably during the ten weeks of culture period, meanwhile, the total weight of culture, due to branch growth, roats and the microtubers will increase up to the end of the inductive period.

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