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Search Results: 1 - 10 of 244 matches for " Kazunari Momma "
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Rimmed Vacuoles in Becker Muscular Dystrophy Have Similar Features with Inclusion Myopathies
Kazunari Momma, Satoru Noguchi, May Christine V. Malicdan, Yukiko K. Hayashi, Narihiro Minami, Keiko Kamakura, Ikuya Nonaka, Ichizo Nishino
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0052002
Abstract: Rimmed vacuoles in myofibers are thought to be due to the accumulation of autophagic vacuoles, and can be characteristic in certain myopathies with protein inclusions in myofibers. In this study, we performed a detailed clinical, molecular, and pathological characterization of Becker muscular dystrophy patients who have rimmed vacuoles in muscles. Among 65 Becker muscular dystrophy patients, we identified 12 patients who have rimmed vacuoles and 11 patients who have deletions in exons 45–48 in DMD gene. All patients having rimmed vacuoles showed milder clinical features compared to those without rimmed vacuoles. Interestingly, the rimmed vacuoles in Becker muscular dystrophy muscles seem to represent autophagic vacuoles and are also associated with polyubiquitinated protein aggregates. These findings support the notion that rimmed vacuoles can appear in Becker muscular dystrophy, and may be related to the chronic changes in muscle pathology induced by certain mutations in the DMD gene.
Distribution of Myxomycetes on Varied Leaf Litter Types in a Mixed Forest in Warm-Temperate Western Japan  [PDF]
Kazunari Takahashi
Open Journal of Forestry (OJF) , 2015, DOI: 10.4236/ojf.2015.57061
Abstract: Myxomycete assemblages were compared on various leaf litters of different vegetation types in a local mixed forest consisting of deciduous and evergreen trees in western Japan. A total of 33 myxomycete species were recorded and associated with the chemical and biological environments of leaf litters under natural condition of the forest floor. Different myxomycete assemblages were found on different sites under the dominant trees in a short distance apart (300 m). A site of Prunus jamasakura tree yielded 21 species, a Quercus glauca tree yielded 20 species, an Ilex pedunculosa tree yielded 12 species, and two Quercus serrata trees yielded 13 and 14 species, respectively. Non-metric multidimensional scaling demonstrated that the myxomycete assemblages were closely related to the litter types of deciduous and evergreen trees, and both litter pH and cellulolytic activity influenced distribution of myxomycete species. Species richness was higher in leaf litters with higher pH than in leaf litters with more acidic pH such as I. pedunculosa litter. The dominant tree litter and litter pH strongly influenced the species distribution of foliicolous myxomycetes in a local mixed forest.
Sport Skill Evaluation with Wearable Sensors and Statistical Analysis  [PDF]
Kazunari Ishida
Open Journal of Social Sciences (JSS) , 2019, DOI: 10.4236/jss.2019.73019
Abstract:
This research discusses sport skill evaluation with wearable sensor and statistical analysis. Skateboarding is selected as the target sport to analyze because it will be an official competition in Tokyo 2020 Olympic Games. Skateboarding is one of the difficult sports because of controlling balance to move forward and to get speed on flat ground. The balance control is a basic trick named Tic-Tac, while the trick is difficult for beginners. To make data set for analyzing Tic-Tac skill, we have provided a basic lesson to research participants. After giving them enough self-training time, we put two inertial sensors on a skateboard and waist of a research participant and got total 41 running data with Tic-Tac. According to the result of statistical analysis on the data, we confirmed that swinging a skateboard left and right is the most important motion to generate moving forward driving forth. This result means that inertial sensors are one of the effective tools to evaluate sport skill for sports science and physical education.
Undifferentiated Pleomorphic Sarcoma of the Cheek with Surface Ulceration: Mimicking Spindle Cell Squamous Cell Carcinoma  [PDF]
Fumiko Momma, Chihiro Onami, Takayuki Konno, Tamio Suzuki
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2013, DOI: 10.4236/jcdsa.2013.33A2001
Abstract:

Undifferentiated pleomorphic sarcoma (UPS), also called malignant fibrous histiocytoma (MFH), belongs to the soft tissue tumors and is more likely in elder patients. UPS currently accounts for approximately 18% of cutaneous soft tissue sarcoma except Kaposi sarcoma. The most common sites are the extremities and head and neck. UPS is rapidly enlarging, and easily invades subcutaneous tissue and muscle without overlying skin changes. UPS tumors, which are confined to subcutaneous tissue, have been reported to be less than 10%. On the other hand, the involvement of the epidermis, occasionally with ulceration, is rare. Here, we describe a case of UPS of the cheek with surface ulceration. An 83-year-old man presented with a 1-year history of a red nodule on his left cheek. The size of the nodule gradually increased. Clinical examination revealed a 55 × 45 mm red, hard mass in the center of his left cheek with a large cratershaped ulcer involving the subcutaneous tissue. The bottom of the ulcer contained necrotic tissue. No cervical lymph nodes were palpable. A biopsy revealed a high-grade, pleomorphic spindle cell neoplasm and frequent abnormal mitotic figures within the dermis. We temporarily diagnosed and suspected a soft tissue sarcoma, but we could not rule out spindle cell squamous cell carcinoma (SCSCC). The patient underwent tumor resection and skin grafting. The tumor had reached the muscle layer of his left cheek with invasion and ulceration of the overlying skin. Histopathological examination of the totally resected tumor revealed a neoplasm of mesenchymal origin, rich in cells with morphology and immunohistochemical characteristics compatible with UPS. Malignant cells were not found in the epidermis. Immunohistochemical analyses were positive for vimentin, α-anti-trypsin, α-smooth muscle actin (α-SMA), and CD10,

Supersymmetric Structure of Spacetime and Matter -Superon Quintet Hypothesis-
Kazunari Shima
Physics , 1998,
Abstract: A unified description of spacetime and matter at the Planck scale is proposed by using the irreducible representation of N=10 extended Super-Poincar\'e algebra, where all matters and all forces except the graviton are the supersymmetric composites made of the fundamental objects with spin 1/2, superon quintet. All the local gauge interactions in GUTs are investigated systematically by using the superon diagrams. The proton is stable and the flavor changing neutral current process is suppressed in the superon pictures of GUTs. The fundamental action of the superon model is proposed. The characteristic predictions which can be tested in the (coming) high energy experiments are discussed briefly.
New Einstein-Hilbert Type Action for Unity of Nature
Kazunari Shima
Physics , 2001, DOI: 10.1002/1521-3978(200205)50:5/7<717::AID-PROP717>3.0.CO;2-B
Abstract: The fundamental action of superon-graviton model(SGM) for space-time and matter is written down explicitly in terms of the fields of the graviton and superons by using the affine and the spin connection formalisms, alternatively. Some characteristic structures including some hidden symmetries of the gravitational coupling of superons are manifested (in two dimensional space-time) with some details of the calculations. SGM cosmology is discussed briefly.
Supersymmetric structure of spacetime and matter -superon-graviton model-
Kazunari Shima
Physics , 2000, DOI: 10.1016/S0370-2693(01)00121-6
Abstract: A unified description of spacetime and matter is proposed by using a single irreducible representation of SO(10) Super-Poincare algebra(SO(10)SPA). All (observed) elementary particles except the graviton are the (massless) eigenstates of SO10)SPA composed of fundamental Nambu-Goldstone fermions with spin 1/2, superons, associating with the spontaneous breakdown of the supertranslation of the spacetime. The systematic investigations of the standard model(SM) and SU(5)GUT by using superon diagrams may reveal the generation structure, the stability of the proton, K-, B-, D- mixings, CP-violation, the atmospheric and solar neutrino deficits and the absence of the electroweak lepton-flavor-mixing. The fundamental action of the superon-graviton model(SGM) for spacetime and matter is proposed, which is invariant under a new supersymmetry.
Minimizing Dispersive Errors in Smoothed Particle Magnetohydrodynamics for Strongly Magnetized Medium
Kazunari Iwasaki
Physics , 2015,
Abstract: In this study, we investigate the dispersive properties of smoothed particle magnetohydrodynamics (SPM) in a strongly magnetized medium by using linear analysis. In modern SPM, a correction term proportional to the divergence of the magnetic fields is subtracted from the equation of motion to avoid a numerical instability arising in a strongly magnetized medium. From the linear analysis, it is found that SPM with the correction term suffer from significant dispersive errors, especially for slow waves propagating along magnetic fields. The phase velocity for all wave numbers is significantly larger than the exact solution and has a peak at a finite wavenumber. These excessively large dispersive errors occur because magnetic fields contribute an unphysical repulsive force along magnetic fields. The dispersive errors cannot be reduced, even with a larger smoothing length and smoother kernel functions such as the Gaussian or quintic spline kernels. We perform the linear analysis for this problem and find that the dispersive errors can be removed completely while keeping SPM stable if the correction term is reduced by half. These findings are confirmed by several simple numerical experiments.
b-Functions associated with quivers of type A
Kazunari Sugiyama
Mathematics , 2010,
Abstract: We study the b-functions of relative invariants of the prehomogeneous vector spaces associated with quivers of type A. By applying the decomposition formula for b-functions, we determine explicitly the b-functions of one variable for each irreducible relative invariant. Moreover, we give a graphical algorithm to determine the b-functions of several variables.
Identifier Migration for Identity Continuance in Single Sign-On  [PDF]
Yoshio Kakizaki, Kazunari Maeda, Keiichi Iwamura
Journal of Information Security (JIS) , 2012, DOI: 10.4236/jis.2012.34037
Abstract: Single sign-on (SSO) is an identity management technique that provides the ability to use multiple Web services with one set of credentials. However, when the authentication server is down or unavailable, users cannot access these Web services, regardless of whether they are operating normally. Therefore, it is important to enable continuous use alongside SSO. In this paper, we present an identity continuance method for SSO. First, we explain four such continuance methods and identify their limitations and problems. Second, we propose a new solution based on an identifier migration approach that meets the requirement for identity continuance. Finally, we discuss these methods from the viewpoint of continuity, security, efficiency, and feasibility.
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