oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2020 ( 3 )

2019 ( 206 )

2018 ( 275 )

2017 ( 294 )

Custom range...

Search Results: 1 - 10 of 224048 matches for " Kazi R "
All listed articles are free for downloading (OA Articles)
Page 1 /224048
Display every page Item
Enigma of the unknown primary in head, neck cancers
Kazi R
Indian Journal of Cancer , 2009,
Abstract:
Perspectives on QOL in India
Kazi R
Indian Journal of Cancer , 2008,
Abstract:
The enigma of proton therapy for head and neck cancers
Kazi R
Journal of Cancer Research and Therapeutics , 2009,
Abstract:
The Life and Times of George Washington Crile
Kazi R
Journal of Postgraduate Medicine , 2003,
Abstract:
Theodor E. Kocher (1841-1917): Nobel Surgeon of the Last Century
Kazi R
Journal of Postgraduate Medicine , 2003,
Abstract:
Christian Albert Theodor Billroth: Master of surgery
Kazi R,Peter R
Journal of Postgraduate Medicine , 2004,
Abstract:
Investigating the Transmission Channels of the Global Financial Crisis to Tanzania  [PDF]
Maduhu Kazi
Modern Economy (ME) , 2014, DOI: 10.4236/me.2014.54032
Abstract:

This paper uses a series of Tanzania’s annual real GDP data for the period of 1970 to 2010, to investigate the transmission channels through which the ongoing financial crisis is affecting the economy. The channels which were examined are foreign aid, export earnings and Foreign Direct Investment (FDI). The paper also investigated how an increase in government expenditure, as popularly known as the stimulus package can boost the Tanzanian economy. Foreign aid was found to possess the positive sign as was expected and is statistically significant. Therefore there is a possibility that the ongoing global crisis has impacted the economy via a reduced foreign aid which is associated with recession in the developed economies; aid donors in this context. It was also found that the global financial crisis had a significant effect on Tanzania’s economic growth through other transmission channels namely FDI and exports. However, all the coefficients were small, indicating the little impact of the global financial crisis to Tanzania’s economy.

Clinical importance of quality of life measures in head and neck cancer
Kazi R,Sayed S,Dwivedi R
Indian Journal of Cancer , 2010,
Abstract:
Src-Like Adaptor Protein (SLAP) Binds to the Receptor Tyrosine Kinase Flt3 and Modulates Receptor Stability and Downstream Signaling
Julhash U. Kazi, Lars R?nnstrand
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0053509
Abstract: Fms-like tyrosine kinase 3 (Flt3) is an important growth factor receptor in hematopoiesis. Gain-of-function mutations of the receptor contribute to the transformation of acute myeloid leukemia (AML). Src-like adaptor protein (SLAP) is an interaction partner of the E3 ubiquitin ligase Cbl that can regulate receptor tyrosine kinases-mediated signal transduction. In this study, we analyzed the role of SLAP in signal transduction downstream of the type III receptor tyrosine kinase Flt3. The results show that upon ligand stimulation SLAP stably associates with Flt3 through multiple phosphotyrosine residues in Flt3. SLAP constitutively interacts with oncogenic Flt3-ITD and co-localizes with Flt3 near the cell membrane. This association initiates Cbl-dependent receptor ubiquitination and degradation. Depletion of SLAP expression by shRNA in Flt3-transfected Ba/F3 cells resulted in a weaker activation of FL-induced PI3K-Akt and MAPK signaling. Meta-analysis of microarray data from patient samples suggests that SLAP mRNA is differentially expressed in different cancers and its expression was significantly increased in patients carrying the Flt3-ITD mutation. Thus, our data suggest a novel role of SLAP in different cancers and in modulation of receptor tyrosine kinase signaling apart from its conventional role in regulation of receptor stability.
Suppressed response to hormonal contraceptives in women of Khairpur, Sindh, Pakistan  [PDF]
Yasmeen Faiz Kazi, Sobia Saleem, Nasreen Kazi
Health (Health) , 2013, DOI: 10.4236/health.2013.511248
Abstract:

Objective: Contraception has gained gradual popularity in many parts of the developing world including Pakistan. Despite this increase in acceptance, the birth rate remains high. Failure of contraception has been reported in the literature, which made us aim to conduct this study. The efficiency of hormonal contraceptives in the study area was assessed and this is the first report from Pakistan. Methods: A total of 200 women (aged 20-30 and 31-40 years; n = 100 each) with minimum consistent use of hormonal contraceptives in the form of pills (Combined oral contraceptives) for 12 months were enrolled in this study. Blood samples were collected from women of each age group and corresponding control groups (n = 100) from local hospitals and reproductive health service center. Serum levels of the fertility hormones viz leutinizing and follicle stimulating hormones were measured through ELISA technique. Results: Our data revealed that over all in the both age groups, 72% women had normal, 16% increased and 12% showed decreased levels of leutinizing hormone (p > 0.05) and 67% women showed normal, 33% showed decreased and no increased levels were found for follicle stimulating hormone (p > 0.05). No age-wise significant difference in response was observed among both the age groups tested. Conclusion: Statistically insignificant difference in serum leutinizing hormone and follicle stimulating hormone seen among both the age groups of hormonal contraceptive users and control group indicates less effective hormonal contraception response in the study area.

Page 1 /224048
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.