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Search Results: 1 - 10 of 1216 matches for " Kay Katrochan "
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O uso da semente de tremo?o como fertilizante azotado
Teixeira,Gon?alo; Katrochan,Kay; Varennes,Amarilis de; Martins,Jo?o Neves; Stuetzel,Hartmut;
Revista de Ciências Agrárias , 2010,
Abstract: we studied the use of lupine seeds as fertilizer to provide a slow release n source. the main objective was to compare different strategies to apply lupine seeds (lupinus angustifolius l. cv. azuro and cv. boruta) as n-fertilizers for a white cabbage crop (brassica oleracea capitata l. cv. impuls). since during the germination process the seedlings use storage carbohydrates as an energy source by respiration, the amount of carbon in the plant and hence the c:n ratio decreases with time. with leaf expansion and the onset of photosynthesis the flow of carbon will invert. thus the main hypothesis of this research was that incorporating germinated lupine seeds after a certain time of growth (when the c:n ratio reached its minimum value) could increase the n release of this plant-derived fertilizer. the incorporation of lupine seeds with a short germination period of 12 days increased the n released from this plant-derived fertilizer. however, n release and cabbage yield were similar in this treatment and when shredded lupine seeds were used, which represent a more practical fertilizing method. the use of shredded does not imply soil tillage needed to prepare the seed bed, sowing, and incorporating of seedlings.
O uso da semente de tremo o como fertilizante azotado The use of lupine seeds as nitrogen fertilizer
Gon?alo Teixeira,Kay Katrochan,Amarilis de Varennes,Jo?o Neves Martins
Revista de Ciências Agrárias , 2010,
Abstract: Neste trabalho, estudou-se o uso de sementes de tremo o como fertilizante para fornecer gradualmente o azoto. O principal objectivo foi comparar diferentes estratégias de aplica o das sementes de tremo o (Lupinus angustifolius L. cv. Azuro e cv. Boruta) na cultura de couve-branca (Brassica oleracea capitata L. cv. Impuls). Uma vez que durante o processo de germina o as plantulas utilizam os seus glúcidos de reserva como fonte de energia na respira o, a quantidade de carbono nas plantulas e consequentemente a sua raz o C:N decresce ao longo do tempo. Com a expans o das folhas e o come o da actividade fotossintética esta tendência inverte-se. Assim, a principal hipótese desta pesquisa foi que a incorpora o de plantulas de tremo o germinadas após um determinado período de tempo (quando a raz o C:N atingia o seu valor mínimo) pode aumentar a liberta o de azoto deste fertilizante azotado de origem vegetal. Com esta pesquisa, descobriu-se que a incorpora o de plantulas de tremo o após 12 dias de germina o pode aumentar a liberta o de azoto. Comparando o referido método de fertiliza o com a incorpora o de sementes de tremo o trituradas, concluiu-se também que uma vez que n o levaram a diferen as entre as liberta es de azoto nem entre a produ o de couve-branca, a incorpora o de sementes de tremo o trituradas deverá ser um método de fertiliza o mais prático, uma vez que este método n o implica os trabalhos de mobiliza o do solo necessários para a prepara o da cama da semente, sementeira e incorpora o das plantulas de tremo o. We studied the use of lupine seeds as fertilizer to provide a slow release N source. The main objective was to compare different strategies to apply lupine seeds (Lupinus angustifolius L. cv. Azuro and cv. Boruta) as N-fertilizers for a white cabbage crop (Brassica oleracea capitata L. cv. Impuls). Since during the germination process the seedlings use storage carbohydrates as an energy source by respiration, the amount of carbon in the plant and hence the C:N ratio decreases with time. With leaf expansion and the onset of photosynthesis the flow of carbon will invert. Thus the main hypothesis of this research was that incorporating germinated lupine seeds after a certain time of growth (when the C:N ratio reached its minimum value) could increase the N release of this plant-derived fertilizer. The incorporation of lupine seeds with a short germination period of 12 days increased the N released from this plant-derived fertilizer. However, N release and cabbage yield were similar in this treatment and when shredded lupine se
Osteoporosis: A Disease of Men  [PDF]
Anu Garg, Samantha Kay
Health (Health) , 2018, DOI: 10.4236/health.2018.101005
Abstract: Objective: The goal of this study was to evaluate osteoporosis screening practices in male patients aged 70 and older. Methods: A survey-based study was carried out over six months at an academic primary care institution in the Midwest. Results: Seventy-nine male patients and fifteen primary care physicians were surveyed. Less than 10% of males recalled being screened for osteoporosis. Two-thirds of physicians reported regularly screening males for osteoporosis. Conclusion: Elderly male patients are overwhelmingly under-screened and undertreated for osteoporosis.
Difficult-to-Treat-Depression and GPs’ Role: Perceptions of Psychiatry Registrars  [PDF]
Kay M. Jones, Leon Piterman
Open Journal of Psychiatry (OJPsych) , 2014, DOI: 10.4236/ojpsych.2014.44037
Abstract: Introduction: For patients, GPs are the most accessible medical resource in the community and are the gatekeepers to other community resources including psychiatrists. Qualifying as a psychiatrist in Australia involves completing a five-year training program that includes rotations in hospitals and community settings. The aims of this research were to 1) explore psychiatry registrars’ perceptions of difficult-to-treat-depression (DTTD) and 2) what they thought about the GPs’ role in this regard. Methods: A semi-structured interview schedule comprising six questions was used; 10 psychiatry registrars (6 females, 4 males) participated in a one-and-half-hour focus group. All were in their final year of training and undertaking a training post in a public hospital in Melbourne, Australia. Data were analysed using the Framework Method. Findings: Similar to GPs and GP trainees, psychiatry registrars’ perceptions and understanding of DTTD varied. While acknowledging limited experience in diagnosis and management, issues important to them included the utility of labels such as DTTD; patients distressed because of another diagnosis, substance abuse and/or life problems, the importance of accurate histories and notes, cost and limited availability of services particularly in the private sector, prescribing regimens, referring to allied health professionals, and suggesting/prescribing non pharmacological and/or complementary treatment. Also what was of concern was communication, both between health professionals and between health professionals and patients. Consensus was that treating depression in general practice is one of the hardest things for GPs to manage but there was value in using mental health plans. Discussion and Conclusion: While this cohort was small in number with limited experience, this study is the first to contribute to the literature that provides some insight into psychiatry registrars’ experiences and perceptions of DTTD. Outcomes may have implications for thepsychiatry training program and GPs who diagnose and manage patients with mental health problems.
Difficult-to-Treat-Depression and GPs’ Role: Perceptions of Psychologists  [PDF]
Kay M. Jones, Leon Piterman
Open Journal of Psychiatry (OJPsych) , 2015, DOI: 10.4236/ojpsych.2015.51005
Abstract: Introduction: Since the Australian Government introduced the “Better Access to Mental Health Services” program in 2006, psychiatrists, psychologists and general practitioners (GPs) have become increasingly involved in service provision for people seeking help with mental health problems. The aim of this research was to a) explore psychologists’ perceptions of difficult to treat depression (DTTD) and b) explore what they thought about the GPs’ role in managing these patient given that most patients are referred to psychologist by GPs. Methods: A previously developed semi-structured interview schedule comprising six questions was used. Seven psychologists participated in a focus group held in Melbourne. Data were analysed using the framework method. Findings, including Discussion: While psychologists understood the term DTTD it was suggested that using different terms may limit understanding between health professionals. Rather than diagnosing, psychologists were more likely to conduct further assessment contextually to confirm GPs’ diagnosis. Communication with GPs was important, particularly when managing “long-term” and suicidal patients. Management included cognitive and behavioural interventions and referring to other mental health services, psychiatrists and/or other allied health professionals. Referral to psychiatrists could be difficult because of limited availability and for some patients, prohibitive costs. Although psychologists discussed non-pharmacological and/or complementary treatment options with patients, they were more likely to rely on GPs to discuss/prescribe these options. Conclusion: While generalisability may be limited, this study is the first to document some understanding of psychologists perceptions of DTTD and the importance of GPs and other health professionals’ role in managing this patient cohort.
Interprofessional Communication and Relationships in the Management of “Difficult to Treat” Depression: Perceptions of the Role of General Practitioners  [PDF]
Kay M. Jones, Leon Piterman
Open Journal of Psychiatry (OJPsych) , 2015, DOI: 10.4236/ojpsych.2015.53029
Abstract: Background: Team based care is an essential ingredient of chronic disease management including chronic mental illness. Effective health care teams include members who have defined, yet intersecting roles, where mutual respect characterises professional interaction and the patient’s well-being is central. The aim was to explore the perception of psychologists, psychiatry registrars and psychiatrists with respect to GPs’ role in managing difficult-to-treat-depression (DTTD). Methods: A previously developed semi-structured interview schedule comprising six questions was used. Thirty-two health professionals participated. Data were analysed using the Framework method. Findings: Four main themes emerged: 1) The team approach was important, particularly to ensure information accuracy and/or when responding to patient needs and pressures; 2) Referrals, usually generated by GPs can be a vehicle for other health professionals to provide advice to the GP; 3) Availability and accessibility often depended on health professionals work location and knowing how to navigate the system; 4) Limited availability of government funding impacts on patients’ accessibility to health professionals. Discussion: Interprofessional relationships were described as paramount. Appropriate and timely referrals are integral to patient management, regardless of challenges. Ongoing challenges include program funding, workforce numbers and costs to patients. Improvement to mental health care access was noted, even for patients among relatively disadvantaged groups and those receiving Medicare Benefits Schedule-subsidised services. Conclusion: Despite adequate GP/specialist communication, the delivery of optimal team based care to patients with difficult-to-treat depression is compromised by lack of access to specialised services and inadequate funding.
Pathobiochemical Changes in Diabetic Skeletal Muscle as Revealed by Mass-Spectrometry-Based Proteomics
Kay Ohlendieck
Journal of Nutrition and Metabolism , 2012, DOI: 10.1155/2012/893876
Abstract: Insulin resistance in skeletal muscle tissues and diabetes-related muscle weakness are serious pathophysiological problems of increasing medical importance. In order to determine global changes in the protein complement of contractile tissues due to diabetes mellitus, mass-spectrometry-based proteomics has been applied to the investigation of diabetic muscle. This review summarizes the findings from recent proteomic surveys of muscle preparations from patients and established animal models of type 2 diabetes. The potential impact of novel biomarkers of diabetes, such as metabolic enzymes and molecular chaperones, is critically examined. Disease-specific signature molecules may be useful for increasing our understanding of the molecular and cellular mechanisms of insulin resistance and possibly identify new therapeutic options that counteract diabetic abnormalities in peripheral organ systems. Importantly, the biomedical establishment of biomarkers promises to accelerate the development of improved diagnostic procedures for characterizing individual stages of diabetic disease progression, including the early detection of prediabetic complications.
Biosimilars: a regulatory perspective from America
Jonathan Kay
Arthritis Research & Therapy , 2011, DOI: 10.1186/ar3310
Abstract: Over the past decade, the availability of targeted biological therapies has revolutionized the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis and holds promise to expand treatment options for patients with systemic lupus erythematosus or other systemic autoimmune diseases. However, the significant cost of these medications creates a major barrier that limits universal access to these effective therapeutic agents. Whereas generic equivalents are commercially available for many small-molecule medications, such lower-cost alternatives to targeted biological therapies are not yet available in the US or the European Union.Biopharmaceuticals are medications, predominantly proteins, that are manufactured using live organisms. These include blood and plasma products, non-recombinant proteins purified from their natural sources, recombinant proteins and monoclonal antibodies produced in cell culture, vaccines, and cultured cellular and tissue products [1]. 'Follow-on' protein products are those 'manufactured using biotechnology or derived from natural sources that are intended to be sufficiently similar to a' biopharmaceutical 'product or products' already approved by a regulatory agency [2]. These are called biosimilars and also have been referred to as biogenerics or biocomparables. A biosimilar product is defined in Section 351 of the Public Health Service (PHS) Act (42 USC § 262) as one which is 'highly similar to the reference product notwithstanding minor differences in clinically inactive components' and for which there are 'no clinically meaningful differences between the bio-logical product and the reference product in terms of safety, purity and potency of the product' [1]. The term 'biogeneric' is now obsolete because, unlike small-molecule generic drugs, a biosimilar is never identical to its reference product.A biosimilar etanercept, manufactured in China by CP Guojian Pharmaceutical Co., Ltd. (Shanghai), is already being mark
Skeletal muscle proteomics: current approaches, technical challenges and emerging techniques
Kay Ohlendieck
Skeletal Muscle , 2011, DOI: 10.1186/2044-5040-1-6
Abstract: Skeletal muscle proteomics attempts to establish the global identification and biochemical characterisation of all members of the muscle-associated protein complement. A considerable number of proteomic studies have employed large-scale separation techniques, such as high-resolution two-dimensional gel electrophoresis or liquid chromatography, and combined them with mass spectrometry as the method of choice for high-throughput protein identification. Muscle proteomics has been applied to the comprehensive biochemical profiling of developing, maturing and aging muscle, as well as the analysis of contractile tissues undergoing physiological adaptations seen in disuse atrophy, physical exercise and chronic muscle transformation. Biomedical investigations into proteome-wide alterations in skeletal muscle tissues were also used to establish novel biomarker signatures of neuromuscular disorders. Importantly, mass spectrometric studies have confirmed the enormous complexity of posttranslational modifications in skeletal muscle proteins.This review critically examines the scientific impact of modern muscle proteomics and discusses its successful application for a better understanding of muscle biology, but also outlines its technical limitations and emerging techniques to establish new biomarker candidates.Proteomics is an unbiased and technology-driven approach for the comprehensive cataloging of entire protein complements and represents an ideal analytical tool for the high-throughput discovery of protein alterations in health and disease [1]. Mass spectrometry-based proteomics is concerned with the global analysis of protein composition, posttranslational modifications and the dynamic nature of expression levels [2-4]. The generation of large data sets on protein expression levels makes proteomics a preeminent hypothesis-generating approach in modern biology [5]. Proteomics has now been accepted as a key technology in biochemistry, cell biology, systems biology and drug
Succession planning for advanced nursing practice; contingency or continuity? The Scottish experience
Kay Currie
Journal of Healthcare Leadership , 2010, DOI: http://dx.doi.org/10.2147/JHL.S7856
Abstract: ccession planning for advanced nursing practice; contingency or continuity? The Scottish experience Review (5454) Total Article Views Authors: Kay Currie Published Date April 2010 Volume 2010:2 Pages 17 - 24 DOI: http://dx.doi.org/10.2147/JHL.S7856 Kay Currie Department of Adult Nursing and Health, Glasgow Caledonian University, Glasgow, Scotland, UK Aim: Succession planning involves identifying key posts within an organization and supporting the ongoing development of individuals ready to move into these roles, thus ensuring continuity of the service. This paper presents an analysis of the succession planning process and illustrates the ways in which key principles may by applied in the case of advanced nursing practice. Background: An array of national policy documents has sought to provide guiding frameworks for effective role development within the National Health Service in Scotland. The growing importance of advanced practice in the contemporary care context might support the assumption that succession planning for these roles would be an integral part of organizational strategy. Key issues: The introduction of advanced practice roles in Scotland has been fragmented and seems largely contingent upon a variety of financial, managerial, and workforce drivers with limited evidence of organizational planning to support role development. Consideration of the elements of the succession planning process, as described in the literature, may improve the sustainability of future initiatives. A variety of flexible educational solutions are available to support staff development for advanced practice, however, the appropriateness of these must be determined in context. Conclusions: The formulation of organizational strategies and operational policies for succession planning is needed to maintain the continuity of advanced practice roles. Research to develop and test implementation models for effective succession planning for advanced practice is required.
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