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Search Results: 1 - 10 of 839 matches for " Kaushik Gopalan "
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Competent Smart Car Parking: An OSGi Approach
Kaushik Gopalan,K. Sairam,R. Nandakrishnan,Veeramuthu Venkatesh
Journal of Artificial Intelligence , 2013,
Abstract: In cosmopolitan expanses, parking of vehicles has become a major problem as it is becoming unproductive. It is also one of the key causes of city traffic congestion. A mechanism is needed to monitor the parking area. Other associated issues such as lighting of large parking lots and tracking availability of parking spots need to be addressed. The proposed study discussed these issues and gave a solution by employing Open Source Gate Initiative (OSGi), a middleware that helps in efficient communication. The parking system discussed here integrates various communication standards such as the SMS features of a standardized mobile, ZigBee enabled proximity sensors and a system meant for storage and processing of the data. The proposed architecture eliminates the hassles of searching empty parking spots and thus can save a lot of time on a daily basis for the general public who own and use a vehicle for commuting. The merits of this study compared with the existing models are emphasized here. This study also highlighted the advantages of using a standardized middleware such as OSGi for the communication between sensors and a system meant for the storage and processing of the obtained data.
Open Journal of Applied Biosensor: Point-of-Care Biosensing and Environment Monitoring  [PDF]
Ajeet Kaushik
Open Journal of Applied Biosensor (OJAB) , 2013, DOI: 10.4236/ojab.2013.24012
Abstract: Open Journal of Applied Biosensor: Point-of-Care Biosensing and Environment Monitoring
Papillary Cystadenoma of Larynx: A Case Report  [PDF]
Tammam Abou Ali, Basel Al Sabah, Kavitha Gopalan, Kavitha Gopalan
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2013, DOI: 10.4236/ijohns.2013.26058
Abstract:

An uncommon clinical entity of papillary cystadenoma of the larynx in a lady of 37-year-old is presented. The diagnosis after clinical examination was achieved by video-stroboscopy, CT scan of the neck, biopsy and histopathological examination. This case study emphasizes the importance of recognition of this lesion by the clinician as the differential diagnosis includes lesions with similar clinical appearance.

 

A Multidirectional Non-Cell Autonomous Control and a Genetic Interaction Restricting Tobacco Etch Virus Susceptibility in Arabidopsis
Suresh Gopalan
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000985
Abstract: Background Viruses constitute a major class of pathogens that infect a variety of hosts. Understanding the intricacies of signaling during host-virus interactions should aid in designing disease prevention strategies and in understanding mechanistic aspects of host and pathogen signaling machinery. Methodology/Principal Findings An Arabidopsis mutant, B149, impaired in susceptibility to Tobacco etch virus (TEV), a positive strand RNA virus of picoRNA family, was identified using a high-throughput genetic screen and a counterselection scheme. The defects include initiation of infection foci, rate of cell-to-cell movement and long distance movement. Conclusions/Significance The defect in infectivity is conferred by a recessive locus. Molecular genetic analysis and complementation analysis with three alleles of a previously published mutant lsp1 (loss of susceptibility to potyviruses) indicate a genetic interaction conferring haploinsufficiency between the B149 locus and certain alleles of lsp1 resulting in impaired host susceptibility. The pattern of restriction of TEV foci on leaves at or near the boundaries of certain cell types and leaf boundaries suggest dysregulation of a multidirectional non-cell autonomous regulatory mechanism. Understanding the nature of this multidirectional signal and the molecular genetic mechanism conferring it should potentially reveal a novel arsenal in the cellular machinery.
ResurfP: a response surface aided parametric test for identifying differentials in GeneChip based oligonucleotide array experiments
Suresh Gopalan
Genome Biology , 2004, DOI: 10.1186/gb-2004-5-11-p14
Abstract: A response surface was plotted by formulating an equation that captures the effect varying threshold of probe-pairs and t-statistic on true positives and false positives identified. The resulting response surface indicate that a wide range of probe-pair and t-statistic combinations yield comparative results. The toplology of the surface was used to define one form of additive cost-based approach - involving t and number of probe-pairs used - to determine the optimum threshold to achieve a good balance of true positives and false positives when comparing two datasets at the probe-level. In addition a data scaling approach was used to study the impact of a selected threshold on the number of false negatives of differing magnitude of differentials in a given dataset.The results indicate that this response surface assisted approach (termed ResurfP) would be effective in determining optimal data-specific threshold for number of probe-pairs used and of the t-statistic when analyzing differentials between two datasets using probe-level data.
Reversal of an immunity associated plant cell death program by the growth regulator auxin
Suresh Gopalan
BMC Research Notes , 2008, DOI: 10.1186/1756-0500-1-126
Abstract: The HR programmed cell death initiated by a bacterial type III secretion system dependent proteinaceous elicitor harpin (from Erwinia amylovora) can be reversed till very late in the process by the plant growth regulator auxin. Early inhibition or late reversal of this cell death program does not affect marker genes correlated with local and systemic resistance. Transgenic plants constitutively modulated in endogenous levels of auxin are not affected in ability or timing of cell death initiated by harpin.These data indicate that the cell death program initiated by harpin can be reversed till late in the process without effect on markers strongly correlated with local and systemic immunity. The constitutive modulation of endogenous auxin does not affect equivalent signaling processes affecting cell death or buffers these signals. The concept and its further study has utility in choosing better strategies for treating mammalian and agricultural diseases.A well studied form of immunity against pathogens in the plant kingdom involves a rapid programmed cell death at the site of infection by the pathogen, associated with restriction of multiplication and spread of the pathogen, termed the hypersensitive response (HR) [1]. Often this HR cell death is accompanied by induction of broad spectrum resistance in uninfected parts of the plants, which is referred to as systemic acquired resistance (SAR). This process is conceptually similar to the requirement of immune activation accompanying apoptosis in some cell types [2]. Apoptosis and many other forms of programmed cell death and many of the components have been identified and extensively studied in different kingdoms [3]. The cell death program and its constituent components in plants is less well understood than the corresponding phenomena (e.g., of aptoptosis) in mammals and other organisms, though existence of mechanistic parallels has been demonstrated [4,5]. The point until which the cell death program can be reversed
Mass fractionation correction of spiked Sr and Nd ratios in dynamic triple collection
K. Gopalan
Chinese Science Bulletin , 1998, DOI: 10.1007/BF02891436
Abstract:
Implementing the Fundamental Right of the Child to Education: The Case of the Andaman and Nicobar Islands
Raghuvaran Gopalan
Socio-Legal Review , 2009,
Abstract: Children have always been a vulnerable group in society. Their needs are secondary in the agenda of the policy maker, and even when these needs are taken into consideration, it is usually done as a token gesture. This note explores an example of this apathy by examining the status of child rights, with a particular focus on education, in the Andaman and Nicobar islands. While the essay primarily relies on information gathered from the ground in January-February, 2005, the issues discussed here have longer shadows. The issue of rights of the child in the Andaman and Nicobar islands has never been closely examined before and the fault lines have never been apparent. The tsunami of 24.12.2004 is not the only source of all the problems that children in the Andaman and Nicobar islands face today; it merely added to the problems that had already existed.
Cultures of Protest in Transnational Contexts: Indian Seamen Abroad, 1885-1945
Gopalan Balachandran
Transforming Cultures , 2008,
Abstract: This paper offers a preliminary exploration of contexts and forms of protest and defiance of authority by Indian seafarers employed on ocean-going steam vessels over six decades to the end of World War II. Though relatively small in numbers and apparently untypical in many respects of a ‘modern’ industrial workforce, the study of Indian seafarers can shed interesting light on several wider aspects of Indian labour history. The transnational and trans-cultural context of employment of Indian seamen also helps illuminate their subjectivities, knowledges, and agencies in ways that are obscured in more insular histories, while their encounters with bosses and others in authority invite us to re-examine pervasive notions of cultural difference–‘owned’ as well as attributed. This paper is not about union-led protests, nor about ‘everyday’ forms of resistance. It dwells instead on a potentially vast and apparently uncharted middle ground of collective resistance by ships’ crews. Such resistance, perhaps simmering for weeks at sea, came to head at key moments, usually upon arrival at a foreign port, close to sailing, or when seamen were being transferred from one vessel to another. It could involve, besides the seamen themselves and their ships’ officers, a swathe of state agencies including local authorities, the police, and the judiciary, though rarely if ever, unions of local seamen. On the evidence here, the culture of work and protest of Indian seamen appears to have been informed by a certain rationality–a certain careful weighing of costs, benefits, and opportunities for engagement and disengagement, including through protest–that is altogether at odds with characteristic representations of Calcutta jute workers and British maritime workers enduring similar circumstances or facing similar ‘choices’. At the same time this culture was open to modern, secular, and transnational solidarities grounded in universalist values. Paradoxes of this nature demand a sustained effort to recover and re-interpret the complex but immensely creative subjectivities that Indian workers and seafarers (and needless to add other Asian, African, and Caribbean workers and seamen) developed and articulated within the fluid and liminal spaces they inhabited.
Quantifying the information of the prior and likelihood in parametric Bayesian modeling
Giri Gopalan
Mathematics , 2015,
Abstract: I suggest using a pair of metrics to quantify the information of the prior and likelihood functions within a parametric Bayesian model, one of which is closely related to the reference prior of Berger and Bernardo. A Monte Carlo algorithm to estimate these metrics is developed and their properties are explored via a combination of theoretical results, simulations, and applications on public medical data sets. I argue that these metrics may be useful diagnostic tools when performing a Bayesian analysis.
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