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Search Results: 1 - 10 of 406743 matches for " Katherine M. Henry "
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Does the inclusion of 'professional development' teaching improve medical students' communication skills?
Katherine Joekes, Lorraine M Noble, Angela M Kubacki, Henry WW Potts, Margaret Lloyd
BMC Medical Education , 2011, DOI: 10.1186/1472-6920-11-41
Abstract: Eighty-two medical students from two consecutive cohorts at a UK medical school completed two videoed consultations with a simulated patient: one at the beginning of year 1 and one at the end of year 2. Group 1 (n = 35) received a traditional pre-clinical curriculum. Group 2 (n = 47) received a curriculum that included communication skills training integrated into a 'professional development' vertical module. Videoed consultations were rated using the Evans Interview Rating Scale by communication skills tutors. A subset of 27% were double-coded. Inter-rater reliability is reported.Students who had received the professional development teaching achieved higher ratings for use of silence, not interrupting the patient, and keeping the discussion relevant compared to students receiving the traditional curriculum. Patient-centred attitudes were not related to observed communication. Students who were less nervous and felt they knew how to listen were rated as better communicators. Students receiving the traditional curriculum and who had been rated as better communicators when they entered medical school performed less well in the final year clinical examination.Students receiving the professional development training showed significant improvements in certain communication skills, but students in both cohorts improved over time. The lack of a relationship between observed communication skills and patient-centred attitudes may be a reflection of students' inexperience in working with patients, resulting in 'patient-centredness' being an abstract concept. Students in the early years of their medical course may benefit from further opportunities to practise basic communication skills on a one-to-one basis with patients.The General Medical Council states that doctors have a duty to 'work in partnership with patients' [1], combining effective clinical communication skills with an attitude towards patients which is respectful and supportive. The national core curriculum for c
The impact of tailored diabetes registry report cards on measures of disease control: a nested randomized trial
Henry H Fischer, Sheri L Eisert, M Josh Durfee, Susan L Moore, Andrew W Steele, Kevin McCullen, Katherine Anderson, Lara Penny, Thomas D Mackenzie
BMC Medical Informatics and Decision Making , 2011, DOI: 10.1186/1472-6947-11-12
Abstract: 5,457 low-income adults with diabetes at eight federally-qualified community health centers participated in this nested randomized trial. Half of the patients received report card mailings quarterly; patients at 4 of 8 clinics received report cards at every clinic visit; and providers at 4 of 8 clinics received quarterly performance feedback with targeted patient-level data. Expert-recommended glycemic, lipid, and blood pressure outcomes were assessed. Assessment of report card utility and patient and provider satisfaction was conducted through mailed patient surveys and mid- and post-intervention provider interviews.Many providers and the majority of patients perceived the patient report card as being an effective tool. However, patient report card mailings did not improve process outcomes, nor did point-of-care distribution improve intermediate outcomes. Clinics with patient-level provider performance feedback achieved a greater absolute increase in the percentage of patients at target for glycemic control compared to control clinics (6.4% vs 3.8% respectively, Generalized estimating equations Standard Error 0.014, p < 0.001, CI -0.131 - -0.077). Provider reaction to performance feedback was mixed, with some citing frustration with the lack of both time and ancillary resources.Patient performance report cards were generally well received by patients and providers, but were not associated with improved outcomes. Targeted, patient-level feedback to providers improved glycemic performance. Provider frustration highlights the need to supplement provider outreach efforts.ClinicalTrials.gov: NCT00827710There is a call for individualization of diabetes outcome targets [1,2] given potential cardiovascular harm in aggressive risk factor modification in subgroups of diabetic patients observed the ACCORD, ACCORD-BP, and INVEST studies [3-5] At the same time, most diabetic patients at our institution and nationwide fall well short of diabetes targets [6] recommended by the Am
PhagoSight: An Open-Source MATLAB? Package for the Analysis of Fluorescent Neutrophil and Macrophage Migration in a Zebrafish Model
Katherine M. Henry, Luke Pase, Carlos Fernando Ramos-Lopez, Graham J. Lieschke, Stephen A. Renshaw, Constantino Carlos Reyes-Aldasoro
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0072636
Abstract: Neutrophil migration in zebrafish larvae is increasingly used as a model to study the response of these leukocytes to different determinants of the cellular inflammatory response. However, it remains challenging to extract comprehensive information describing the behaviour of neutrophils from the multi-dimensional data sets acquired with widefield or confocal microscopes. Here, we describe PhagoSight, an open-source software package for the segmentation, tracking and visualisation of migrating phagocytes in three dimensions. The algorithms in PhagoSight extract a large number of measurements that summarise the behaviour of neutrophils, but that could potentially be applied to any moving fluorescent cells. To derive a useful panel of variables quantifying aspects of neutrophil migratory behaviour, and to demonstrate the utility of PhagoSight, we evaluated changes in the volume of migrating neutrophils. Cell volume increased as neutrophils migrated towards the wound region of injured zebrafish. PhagoSight is openly available as MATLAB? m-files under the GNU General Public License. Synthetic data sets and a comprehensive user manual are available from http://www.phagosight.org.
Evolution of Genome Size and Complexity in Pinus
Alison M. Morse, Daniel G. Peterson, M. Nurul Islam-Faridi, Katherine E. Smith, Zenaida Magbanua, Saul A. Garcia, Thomas L. Kubisiak, Henry V. Amerson, John E. Carlson, C. Dana Nelson, John M. Davis
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0004332
Abstract: Background Genome evolution in the gymnosperm lineage of seed plants has given rise to many of the most complex and largest plant genomes, however the elements involved are poorly understood. Methodology/Principal Findings Gymny is a previously undescribed retrotransposon family in Pinus that is related to Athila elements in Arabidopsis. Gymny elements are dispersed throughout the modern Pinus genome and occupy a physical space at least the size of the Arabidopsis thaliana genome. In contrast to previously described retroelements in Pinus, the Gymny family was amplified or introduced after the divergence of pine and spruce (Picea). If retrotransposon expansions are responsible for genome size differences within the Pinaceae, as they are in angiosperms, then they have yet to be identified. In contrast, molecular divergence of Gymny retrotransposons together with other families of retrotransposons can account for the large genome complexity of pines along with protein-coding genic DNA, as revealed by massively parallel DNA sequence analysis of Cot fractionated genomic DNA. Conclusions/Significance Most of the enormous genome complexity of pines can be explained by divergence of retrotransposons, however the elements responsible for genome size variation are yet to be identified. Genomic resources for Pinus including those reported here should assist in further defining whether and how the roles of retrotransposons differ in the evolution of angiosperm and gymnosperm genomes.
Proteasome Inhibition Promotes Parkin-Ubc13 Interaction and Lysine 63-Linked Ubiquitination
Grace G. Y. Lim, Katherine C. M. Chew, Xiao-Hui Ng, Adeline Henry-Basil, Roy W. X. Sim, Jeanne M. M. Tan, Chou Chai, Kah-Leong Lim
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0073235
Abstract: Disruption of the ubiquitin-proteasome system, which normally identifies and degrades unwanted intracellular proteins, is thought to underlie neurodegeneration. Supporting this, mutations of Parkin, a ubiquitin ligase, are associated with autosomal recessive parkinsonism. Remarkably, Parkin can protect neurons against a wide spectrum of stress, including those that promote proteasome dysfunction. Although the mechanism underlying the preservation of proteasome function by Parkin is hitherto unclear, we have previously proposed that Parkin-mediated K63-linked ubiquitination (which is usually uncoupled from the proteasome) may serve to mitigate proteasomal stress by diverting the substrate load away from the machinery. By means of linkage-specific antibodies, we demonstrated here that proteasome inhibition indeed promotes K63-linked ubiquitination of proteins especially in Parkin-expressing cells. Importantly, we further demonstrated that the recruitment of Ubc13 (an E2 that mediates K63-linked polyubiquitin chain formation exclusively) by Parkin is selectively enhanced under conditions of proteasomal stress, thus identifying a mechanism by which Parkin could promote K63-linked ubiquitin modification in cells undergoing proteolytic stress. This mode of ubiquitination appears to facilitate the subsequent clearance of Parkin substrates via autophagy. Consistent with the proposed protective role of K63-linked ubiquitination in times of proteolytic stress, we found that Ubc13-deficient cells are significantly more susceptible to cell death induced by proteasome inhibitors compared to their wild type counterparts. Taken together, our study suggests a role for Parkin-mediated K63 ubiquitination in maintaining cellular protein homeostasis, especially during periods when the proteasome is burdened or impaired.
Genetic Diversity of Arginine Catabolic Mobile Element in Staphylococcus epidermidis
Maria Miragaia,Herminia de Lencastre,Francoise Perdreau-Remington,Henry F. Chambers,Julie Higashi,Paul M. Sullam,Jessica Lin,Kester I. Wong,Katherine A. King,Michael Otto,George F. Sensabaugh,Binh An Diep
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0007722
Abstract: The methicillin-resistant Staphylococcus aureus clone USA300 contains a novel mobile genetic element, arginine catabolic mobile element (ACME), that contributes to its enhanced capacity to grow and survive within the host. Although ACME appears to have been transferred into USA300 from S. epidermidis, the genetic diversity of ACME in the latter species remains poorly characterized.
Riemann and Euler Sum Investigation in an Introductory Calculus Class  [PDF]
Michael M. Henry, Dennis M. Cates
Open Journal of Discrete Mathematics (OJDM) , 2011, DOI: 10.4236/ojdm.2011.12007
Abstract: This paper provides a detailed outline of a mathematical research exploration for use in an introductory high school or college Calculus class and is directed toward teachers of such courses. The discovery is accomplished by introducing a novel method to generate a polynomial expression for each of the Euler sums, ΣNk=0kn,n∈Z+ . The described method flows simply from initial discussions of the Riemann sum definition of a definite integral and is readily accessible to all new calculus students. Students investigate the Bernoulli numbers and the interesting connections with Pascal's Triangle. Advice is offered throughout as to how the project can be assigned to students and offers multiple suggestions for additional exploration for any motivated student.
An Analysis of Fights in the National Hockey League  [PDF]
Henry L. Castillo, Paul M. Sommers
Open Journal of Statistics (OJS) , 2017, DOI: 10.4236/ojs.2017.74047
Abstract: The authors use data from fight logs during the 2016-2017 regular National Hockey League (NHL) season to test for a difference in the proportion of games with and without fights for each of the thirty NHL teams. Only one team (Toronto Maple Leafs) was more likely to be involved in a fight at a home game than at an away game. Teams that fought proportionally more often in the second half of the season made the playoffs; teams that fought significantly less often did not. And, long distance air travel (flights involving more than 1000 miles or trips that required crossing at least one time zone) resulted in disproportionately more games with fights for eight different NHL teams.
Consumo patológico de alcohol entre los estudiantes de la Universidad de Cartagena, 2008
Arrieta Vergara,Katherine M.;
Revista de Salud Pública , 2009, DOI: 10.1590/S0124-00642009000600004
Abstract: objective determining the frequency of pathological alcohol consumption and characterising the variables related to such consumption in students taking daytime programmes at the university of cartagena. methods a descriptive cross-sectional design was used; 1,031 students from daytime programmes at the university of cartagena participated in it (480 males and 551 females). they were selected by randomly sampling responses to a questionnaire which included the alcohol use disorders identification test (audit). stata 9.1 software was used for single variable analysis. results 34.5 % of the students displayed a high risk of consumption, mainly males (41.1 %). total consumption was 83.6 %, median age for the most frequent consumption was 15/16 (38 %), beer being the preferred drink (65 %). reported problems included alcohol poisoning (68 %), physical ailments (58 %), light headedness (30 %), having sex without protection (19 %) and family problems (12 %). conclusions alcohol consumption amongst college students was high, as was their tendency to consume dangerous quantities, mainly males having low-consumption characteristics (once a month or less) but consuming large amounts (5 drinks or more) on such occasions.
Los usos del sexo
Franke,Katherine M;
Revista de Estudios Sociales , 2007,
Abstract: this article analyzes how the social and legal classification of certain injuries as "sexual" or "sexbased" risks telling us too much and not enough about the kind of harm these injuries inflict. this classification both overdetermines the conduct and the injury as sexual and underdetermines other aspects of the conduct and the injury that get crowded out once the "sexual" label is applied - aspects such as racial, nationalistic or religious. using three examples - the interpretations by some anthropologists of the seminal practices of the sambia in new guinea as a kind of "ritualized homosexuality," the attack against haitian immigrant abner louima by new york city police officers, and the rapes and other assaults against men and women by soldiers in the former yugoslavia - the article shows how the notion of "sexual practices" or "sexual crime" can hide gender, racial, and religious discrimination. with this in mind, it proposes a move from the discretionary legal use of the "sexual" towards a revision of violence from the perspective of international human rights law. we cannot, the article concludes, lose sight of "the uses of sex in the construction of men, masculinity and nations and in the destruction of women, men and the people."
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